Publications (Department Neurogenetics)

Frühbeis, C.; Kuo-Elsner, W. P.; Müller, C.; Barth, K.; Peris, L.; Tenzer, S.; Möbius, W.; Werner, H. B.; Nave, K.-A.; Fröhlich, D. et al.; Krämer-Albers, E.-M.: Oligodendrocytes support axonal transport and maintenance via exosome secretion. PLoS Biology 18, e3000621 (2020)

Trevisiol, A.; Kusch, K.; Steyer, A. M.; Gregor, I.; Nardis, C.; Winkler, U.; Köhler, S.; Restrepo, A.; Möbius, W.; Werner, H. B. et al.; Nave, K.-A.; Hirrlinger, J.: Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia. PLoS Biology 18 (11), e3000943 (2020)

Moore, S.; Meschkat, M.; Ruhwedel, T.; Trevisiol, A.; Tzvetanova, I.; Battefeld, A.; Kusch, K.; Kole, M. H. P.; Strenzke, N.; Möbius, W. et al.; de Hoz, L.; Nave, K.-A.: A role of oligodendrocytes in information processing. Nature Communications 11 (1), 5497 (2020)

Wu, S.; Stone, S.; Nave, K.-A.; Lin, W.: The integrated UPR and ERAD in oligodendrocytes maintains myelin thickness in adults by regulating myelin protein translation. The Journal of Neuroscience 40 (43), pp. 8214 - 8232 (2020)

Brebner, L. S.; Ziminski, J. J.; Margetts‐Smith, G.; Sieburg, M. C.; Hall, C. N.; Heintz, T. G.; Lagnado, L.; Hirrlinger, J.; Crombag, H. S.; Koya, E.: Extinction of cue‐evoked food‐seeking recruits a GABAergic interneuron ensemble in the dorsal medial prefrontal cortex of mice. European Journal of Neuroscience 52 (7), pp. 3723 - 3737 (2020)

Prukop, T.; Wernick, S.; Boussicault, L.; Ewers, D.; Jäger, K.; Adam, J.; Winter, L.; Quintes, S.; Linhoff, L.; Barrantes‐Freer, A. et al.; Bartl, M.; Czesnik, D.; Zschüntzsch, J.; Schmidt, J.; Primas, G.; Laffaire, J.; Rinaudo, P.; Brureau, A.; Nabirotchkin, S.; Schwab, M. H.; Nave, K.-A.; Hajj, R.; Cohen, D.; Sereda, M. W.: Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot–Marie–Tooth disease type 1A (CMT1A) rats. Journal of Neuroscience Research 98 (10), pp. 1933 - 1952 (2020)

Eichel, M. A.; Gargareta, V.-I.; D’Este, E.; Fledrich, R.; Kungl, T.; Buscham, T. J.; Lüders, K. A.; Miracle, C.; Jung, R. B.; Distler, U. et al.; Kusch, K.; Möbius, W.; Hülsmann, S.; Tenzer, S.; Nave, K.-A.; Werner, H. B.: CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves. Nature Communications 11 (1), 4514 (2020)

Natsubori, A.; Tsunematsu, T.; Karashima, A.; Imamura, H.; Kabe, N.; Trevisiol, A.; Hirrlinger, J.; Kodama, T.; Sanagi, T.; Masamoto, K. et al.; Takata, N.; Nave, K.-A.; Matsui, K.; Tanaka, K.F.; Honda, M.: Intracellular ATP levels in mouse cortical excitatory neurons varies with sleep–wake states. Communications Biology 3 (1), 491 (2020)

Jahn, O.; Siems, S. B.; Kusch, K.; Hesse, D.; Jung, R. B.; Liepold, T.; Uecker, M.; Sun, T.; Werner, H. B.: The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay. Frontiers in Cellular Neuroscience 14, 249 (2020)

Mukherjee, C.; Kling, T.; Russo, B.; Miebach, K.; Kess, E.; Schifferer, M.; Pedro, L. D.; Weikert, U.; Fard, M. K.; Kannaiyan, N. et al.; Rossner, M.; Aicher, M.-L.; Goebbels, S.; Nave, K.-A.; Krämer-Albers, E.-M.; Schneider, A.; Simons, M.: Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain. Cell Metabolism 32 (2), pp. 259 - 272.e10 (2020)

Rudnik‐Schöneborn, S.; Thiele, S.; Walter, M. C.; Reinecke, L.; Sereda, M. W.; Schöneborn, R.; Elbracht, M.: Pregnancy outcome in Charcot–Marie–Tooth disease: results of the CMT‐NET cohort study in Germany. European Journal of Neurology 27 (8), pp. 1390 - 1396 (2020)

Stephan, T.; Brüser, C.; Deckers, M.; Steyer, A. M.; Balzarotti, F.; Barbot, M.; Behr, T. S.; Heim, G.; Hübner, W.; Ilgen, P. et al.; Lange, F.; Pacheu‐Grau, D.; Pape, J. K.; Stoldt, S.; Huser, T.; Hell, S. W.; Möbius, W.; Rehling, P.; Riedel, D.; Jakobs, S.: MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation. The EMBO Journal 39 (14), e104105 (2020)

Marshall-Phelps, K. L. H.; Kegel, L.; Baraban, M.; Ruhwedel, T.; Almeida, R. G.; Rubio-Brotons, M.; Klingseisen, A.; Benito-Kwiecinski, S. K.; Early, J. J.; Bin, J. M. et al.; Suminaite, D.; Livesey, M. R.; Möbius, W.; Poole, R. J.; Lyons, D. A.: Neuronal activity disrupts myelinated axon integrity in the absence of NKCC1b. Journal of Cell Biology 219 (7), e201909022 (2020)

Fredrickx, E.; Colombo, E.; Canevazzi, P.; La Marca, R.; Pellegatta, M.; Dina, G.; Podini, P.; Nave, K.-A.; Quattrini, A.; Taveggia, C.: Ablation of neuronal ADAM17 impairs oligodendrocyte differentiation and myelination. Glia 68 (6), pp. 1148 - 1164 (2020)

Gruenenfelder, F. I.; McLaughlin, M.; Griffiths, I. R.; Garbern, J.; Thomson, G.; Kuzman, P.; Barrie, J. A.; McCulloch, M.-l.; Penderis, J.; Stassart, R. et al.; Nave, K.-A.; Edgar, J. M.: Neural stem cells restore myelin in a demyelinating model of Pelizaeus-Merzbacher disease. Brain 143 (5), pp. 1383 - 1399 (2020)

Steyer, A. M.; Ruhwedel, T.; Nardis, C.; Werner, H. B.; Nave, K.-A.; Möbius, W.: Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy. Journal of Structural Biology 210 (2), 107492 (2020)

Luo, L.; Ambrozkiewicz, M.; Benseler, F.; Chen, C.; Dumontier, E.; Falkner, S.; Furlanis, E.; Gomez, A. M.; Hoshina, N.; Huang, W.-H. et al.; Hutchison, M. A.; Itoh-Maruoka, Y.; Lavery, L. A.; Li, W.; Maruo, T.; Motohashi, J.; Pai, E. L.-L.; Pelkey, K. A.; Pereira, A.; Philips, T.; Sinclair, J. L.; Stogsdill, J. A.; Traunmüller, L.; Wang, J.; Wortel, J.; You, W.; Abumaria, N.; Beier, K. T.; Brose, N.; Burgess, H. A.; Cepko, C. L.; Cloutier, J.-F.; Eroglu, C.; Goebbels, S.; Kaeser, P. S.; Kay, J. N.; Lu, W.; Luo, L.; Mandai, K.; McBain, C. J.; Nave, K.-A.; Prado, M. A.M.; Prado, V. F.; Rothstein, J.; Rubenstein, J. L.R.; Saher, G.; Sakimura, K.; Sanes, J. R.; Scheiffele, P.; Takai, Y.; Umemori, H.; Verhage, M.; Yuzaki, M.; Zoghbi, H. Y.; Kawabe, H.; Craig, A. M.: Optimizing nervous system-specific gene targeting with Cre driver lines: prevalence of germline recombination and influencing factors. Neuron 106 (1), pp. 37 - 65.e5 (2020)

Tasche, D.; Weber, M.; Mrotzek, J.; Gerhard, C.; Wieneke, S.; Möbius, W.; Höfft, O.; Viöl, W.: In Situ Investigation of the Formation Kinematics of Plasma-Generated Silver Nanoparticles. Nanomaterials 10 (3), 555 (2020)

Stone, S.; Wu, S.; Nave, K.-A.; Lin, W.: The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP. JCI Insight 5 (5), e132364 (2020)

Wakhloo, D.; Scharkowski, F.; Curto, Y.; Butt, U. J.; Bansal, V.; Steixner-Kumar, A. A.; Wüstefeld, L.; Rajput, A.; Arinrad, S.; Zillmann, M. R. et al.; Seelbach, A.; Hassouna, I.; Schneider, K.; Qadir Ibrahim, A.; Werner, H. B.; Werner, H. B.; Martens, H.; Miskowiak, K.; Wojcik, S. M.; Wojcik, S. M.; Bonn, S.; Nacher, J.; Nave, K. A.; Ehrenreich, H.: Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin. Nature Communications 11, 1313 (2020)

Siems, S. B.; Jahn, O.; Eichel, M. A.; Kannaiyan, N.; Wu, L. M. N.; Sherman, D. L.; Kusch, K.; Hesse, D.; Jung, R. B.; Fledrich, R. et al.; Sereda, M. W.; Rossner, M. J.; Brophy, P. J.; Werner, H. B.: Proteome profile of peripheral myelin in healthy mice and in a neuropathy model. eLife 9, e51406 (2020)

Kalinin, S.; Meares, G. P.; Lin, S. X.; Pietruczyk, E. A.; Saher, G.; Spieth, L.; Nave, K.-A.; Boullerne, A. I.; Lutz, S. E.; Benveniste, E. N. et al.; Feinstein, D. L.: Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis. Glia 68 (3), pp. 600 - 616 (2020)

Rosiewicz, K. S.; Crowley, T.; Saher, G.; Kerkering, J.; Alisch, M.; Siffrin, V.: Comparison of RNA isolation procedures for analysis of adult murine brain and spinal cord astrocytes. Journal of Neuroscience Methods 333, 108545 (2020)

Cohen, C. C. H.; Popovic, M. A.; Klooster, J.; Weil, M.-T.; Möbius, W.; Nave, K.-A.; Kole, M. H. P.: Saltatory Conduction along Myelinated Axons Involves a Periaxonal Nanocircuit. Cell 180 (2), pp. 311 - 322.e15 (2020)

Brebner, L. S.; Ziminski, J. L.; Margetts-Smith, G.; Sieburg, M. C.; Reeve, H. M.; Nowotny, T.; Hirrlinger, J.; Heintz, T.; Lagnado, L.; Kato, S. et al.; Kobajashi, K.; Ramsey, L. A.; Hall, C.; Crombag, H. S.; Koya, E.: The emergence of a stable neuronal ensemble from a wider pool of activated neurons in the dorsal medial prefrontal cortex during appetitive learning in mice. The Journal of Neuroscience 40 (2), pp. 395 - 410 (2020)

Hennies, J.; Lleti, J. M. S.; Schieber, N. L.; Templin, R. M.; Steyer, A. M.; Schwab, Y.: AMST: Alignment to Median Smoothed Template for Focused Ion Beam Scanning Electron Microscopy Image Stacks. Scientific Reports 10, 2004 (2020)