Publications of Hiroshi Kawabe

Blackburn, D. M.; Sahinyan, K.; Hernández-Corchado, A.; Lazure, F.; Richard, V.; Raco, L.; Perron, G.; Zahedi, R. P.; Borchers, C. H.; Lepper, C. et al.; Kawabe, H.; Jahani-Asl, A.; Najafabadi, H. S.; Soleimani, V. D.: The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation. iScience 27 (7), 110241 (2024)

Altas, B.; Rhee, H. J.; Ju, A.; Solis, H. C.; Karaca, S.; Winchenbach, J.; Kaplan-Arabaci, O.; Schwark, M.; Ambrozkiewicz, M.; Lee, C. et al.; Spieth, L.; Wieser, G. L.; Chaugule, V. K.; Majoul, I.; Hassan, M. A.; Goel, R.; Wojcik, S. M.; Koganezawa, N.; Hanamura, K.; Rotin, D.; Pichler, A.; Mitkovski, M.; de Hoz, L.; Poulopoulos, A.; Urlaub, H.; Jahn, O.; Saher, G.; Brose, N.; Rhee, J.; Kawabe, H.: Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology 223 (1), e201902050 (2024)

Dhume, S. H.; Connor, S. A.; Mills, F.; Tari, P. K.; Au-Yeung, S. H.; Karimi, B.; Oku, S.; Roppongi, R. T.; Kawabe, H.; Bamji, S. X. et al.; Wang, Y. T.; Brose, N.; Jackson, M. F.; Craig, A. M.; Siddiqui, T. J.: Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits. eLife 11, e64742 (2022)

Ambrozkiewicz, M.; Borisova, E.; Schwark, M.; Ripamonti, S.; Schaub, T.; Smorodchenko, A.; Weber, A. I.; Rhee, H. J.; Altas, B.; Yilmaz, R. et al.; Mueller, S.; Piepkorn, L.; Horan, S. T.; Straussberg, R.; Zaqout, S.; Jahn, O.; Dere, E.; Rosário, M.; Boehm-Sturm, P.; Borck, G.; Willig, K. I.; Rhee, J. S.; Tarabykin, V.; Kawabe, H.: The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc. Molecular Psychiatry 26, pp. 1980 - 1995 (2021)

Luo, L.; Ambrozkiewicz, M.; Benseler, F.; Chen, C.; Dumontier, E.; Falkner, S.; Furlanis, E.; Gomez, A. M.; Hoshina, N.; Huang, W.-H. et al.; Hutchison, M. A.; Itoh-Maruoka, Y.; Lavery, L. A.; Li, W.; Maruo, T.; Motohashi, J.; Pai, E. L.-L.; Pelkey, K. A.; Pereira, A.; Philips, T.; Sinclair, J. L.; Stogsdill, J. A.; Traunmüller, L.; Wang, J.; Wortel, J.; You, W.; Abumaria, N.; Beier, K. T.; Brose, N.; Burgess, H. A.; Cepko, C. L.; Cloutier, J.-F.; Eroglu, C.; Goebbels, S.; Kaeser, P. S.; Kay, J. N.; Lu, W.; Luo, L.; Mandai, K.; McBain, C. J.; Nave, K.-A.; Prado, M. A.M.; Prado, V. F.; Rothstein, J.; Rubenstein, J. L.R.; Saher, G.; Sakimura, K.; Sanes, J. R.; Scheiffele, P.; Takai, Y.; Umemori, H.; Verhage, M.; Yuzaki, M.; Zoghbi, H. Y.; Kawabe, H.; Craig, A. M.: Optimizing nervous system-specific gene targeting with Cre driver lines: prevalence of germline recombination and influencing factors. Neuron 106 (1), pp. 37 - 65.e5 (2020)

Hoshino, S.; Kobayashi, M.; Tagawa, R.; Konno, R.; Abe, T.; Furuya, K.; Miura, K.; Wakasawa, H.; Okita, N.; Sudo, Y. et al.; Mizunoe, Y.; Nakagawa, Y.; Nakamura, T.; Kawabe, H.; Higami, Y.: WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism. Febs Open Bio (2020)

Ambrozkiewicz, M.; Schwark, M.; Kishimoto-Suga, M.; Borisova, E.; Hori, K.; Salazar-Lázaro, A.; Rusanova, A.; Altas, B.; Piepkorn, L.; Bessa, P. et al.; Schaub, T.; Zhang, X.; Rabe, T.; Ripamonti, S.; Rosário, M.; Akiyama, H.; Jahn, O.; Kobayashi, T.; Hoshino, M.; Tarabykin, V.; Kawabe, H.: Polarity acquisition in cortical neurons is driven by synergistic action of Sox9-regulated Wwp1 and Wwp2 E3 ubiquitin ligases and intronic miR-140. Neuron 100 (5), p. 1097 (2018)

Ogawa, M.; Matsuda, R.; Takada, N.; Tomokiyo, M.; Yamamoto, S.; Shizukusihi, S.; Yamaji, T.; Yoshikawa, Y.; Yoshida, M.; Tanida, I. et al.; Koike, M.; Murai, M.; Morita, H.; Takeyama, H.; Ryo, A.; Guan, J.-L.; Yamamoto, M.; Inoue, J.-i.; Yanagawa, T.; Fukuda, M.; Kawabe, H.; Ohnishi, M.: Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination. Cellular Microbiology 20 (8), e12846 (2018)

Bhouri, M.; Morishita, W.; Temkin, P.; Goswami, D.; Kawabe, H.; Brose, N.; Südhof, T. C.; Craig, A. M.; Siddiqui, T. J.; Malenka, R.: Deletion of LRRTM1 and LRRTM2 in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons. Proceedings of the National Academy of Sciences of the United States of America 115 (23), pp. E5382 - E5389 (2018)

Crosby, J. R.; Zhao, C.; Jiang, C.; Bai, D.; Katz, M.; Greenlee, S.; Kawabe, H.; McCaleb, M.; Rotin, D.; Guo, S. et al.; Monia, B. P.: Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice. Journal of cystic fibrosis 16 (6), pp. 671 - 680 (2017)

Henshall, T. L.; Manning, J. A.; Alfassy, O. S.; Goel, P.; Boase, N. A.; Kawabe, H.; Kumar, S.: Deletion of Nedd4-2 results in progressive kidney disease in mice. Cell Death and Differentiation 24, pp. 2150 - 2160 (2017)

Zhou, Z.; Kawabe, H.; Suzuki, A.; Shinmyozu, K.; Saga, Y.: NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes. Nature Communications 8, 15662 (2017)

Sigler, A.; Oh, W. C.; Imig, C.; Altas, B.; Kawabe, H.; Cooper, B. H.; Kwon, H.-B.; Rhee, J.-S.; Brose, N.: Formation and maintenance of functional spines in the absence of presynaptic glutamate release. Neuron 94, pp. 304 - 311 (2017)

Kawabe, H.; Mitkovski, M.; Kaeser, P. S.; Hirrlinger, J.; Opazo, F.; Nestvogel, D.; Kalla, S.; Fejtova, A.; Verrier, S. E.; Bungers, S. R. et al.; Cooper, B. H.; Varoqueaux, F.; Wang, Y.; Nehring, R. B.; Gundelfinger, E. D.; Rosenmund, C.; Rizzoli, S. O.; Südhof, T. C.; Rhee, J.-S.; Brose, N.: ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones. The Journal of Cell Biology 216 (4), pp. 1143 - 1161 (2017)

Ripamonti, S.; Ambrozkiewicz, M.; Guzzi, F.; Gravati, M.; Biella, G.; Bormuth, I.; Hammer, M.; Tuffy, L.; Sigler, A.; Kawabe, H. et al.; Nishimori, K.; Toselli, M.; Brose, N.; Parenti, M.; Rhee, J.: Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. eLife 6, e22466 (2017)

Altas, B.; Jahn, O.; Kawabe, H.: Biochemical purification of binding partners of synaptic scaffold proteins. Methods in molecular biology 1538, pp. 69 - 82 (2017)

Jiang, C.; Kawabe, H.; Rotin, D.: The ubiquitin ligase Nedd4L regulates the Na/K/2Cl co-transporter NKCC1/SLC12A2 in the colon. The Journal of Biological Chemistry 292 (8), pp. 3137 - 3145 (2017)

Pei, G.; Buijze, H.; Liu, H.; Moura-Alves, P.; Goosmann, C.; Brinkmann, V.; Kawabe, H.; Dorhoi, A.; Kaufmann, S. H.E.: The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy. Autophagy 13 (12), pp. 2041 - 2055 (2017)

Lee, J.-H.; Jeon, S.-A.; Kim, B.-G.; Takeda, M.; Cho, J.-J.; Kim, D.-I.; Kawabe, H.; Cho, J.-Y.: Nedd4 deficiency in vascular smooth muscle promotes vascular calcification by stabilizing pSmad1. Journal of Bone and Mineral Research 32 (5), pp. 927 - 938 (2016)

Canal, M.; Martín-Flores, N.; Pérez-Sisqués, L.; Romaní-Aumedes, J.; Altas, B.; Man, H.-Y.; Kawabe, H.; Alberch, J.; Malagelada, C.: Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease. Oncotarget 7 (37), pp. 58813 - 58831 (2016)