Publications Neurogenetics

1.

Journal Article

Nave, K.-A.; Asadollahi, E.; Sasmita, A. O.: Expanding the function of oligodendrocytes to brain energy metabolism. Current Opinion in Neurobiology 83, 102782 (2023)

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2.

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Ehrenreich, H.; Gassmann, M.; Poustka, L.; Burtscher, M.; Hammermann, P.; Sirén, A.-L.; Nave, K.-A.; Miskowiak, K.: Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress. Neuroprotection 1 (1), pp. 9 - 19 (2023)

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3.

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Michanski, S.; Kapoor, R.; Steyer, A. M.; Möbius, W.; Früholz, I.; Ackermann, F.; Gueltas, M.; Garner, C. C.; Hamra, F. K.; Neef, J. et al.; Strenzke, N.; Moser, T.; Wichmann, C.: Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing. EMBO Reports 24 (9), e56702 (2023)

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4.

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Singh, M.; Zhao, Y.; Daguano Gastaldi, V.; Wojcik, S. M.; Curto, Y.; Kawaguchi, R.; Merino, R.M.; Garcia-Agudo, L. F.; Taschenberger, H.; Brose, N. et al.; Geschwind, D.; Nave, K.-A.; Ehrenreich, H.: Erythropoietin re-wires cognition-associated transcriptional networks. Nature Communications 14, 4777 (2023)

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5.

Journal Article

Michanski, S.; Henneck, T.; Mukhopadhyay, M.; Steyer, A. M.; Gonzalez, P.A.; Grewe, K.; Ilgen, P.; Gültas, M.; Fornasiero, E.F.; Jakobs, S. et al.; Möbius, W.; Vogl, C.; Pangršič, T.; Rizzoli, S.O.; Wichmann, C.: Age-dependent structural reorganization of utricular ribbon synapses. Frontiers in Cell and Developmental Biology 11, 1178992 (2023)

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6.

Journal Article

Bai, X.; Zhao, N.; Koupourtidou, C.; Fang, L.-P.; Schwarz, V.; Caudal, L. C.; Zhao, R.; Hirrlinger, J.; Walz, W.; Bian, S. et al.; Huang, W.; Ninkovic, J.; Kirchhoff, F.; Scheller, A.: In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury. Developmental Cell 58 (13), pp. 1153 - 1169.e5 (2023)

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7.

Journal Article

Saher, G.: Cholesterol Metabolism in Aging and Age-Related Disorders. Annual Review of Neuroscience 46, pp. 59 - 78 (2023)

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8.

Journal Article

Schäffner, E.; Bosch-Queralt, M.; Edgar, J. M.; Lehning, M.; Strauß, J.; Fleischer, N.; Kungl, T.; Wieghofer, P.; Berghoff, S. A.; Reinert, T. et al.; Krueger, M.; Morawski, M.; Möbius, W.; Barrantes-Freer, A.; Stieler, J.; Sun, T.; Saher, G.; Schwab, M. H.; Wrede, C.; Frosch, M.; Prinz, M.; Reich, D. S.; Flügel, A.; Stadelmann, C.; Fledrich, R.; Nave, K.-A.; Stassart, R. M.: Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease. Nature Neuroscience 26, pp. 1218 - 1228 (2023)

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9.

Journal Article

Nave, K.-A.; Stassart, R. M.: Lack of myelin improves axon survival in inflammatory lesions in the CNS. Nature Neuroscience 26, pp. 1145 - 1146 (2023)

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10.

Journal Article

Sadigurschi, N.; Scrift, G.; Hirrlinger, J.; Golan, H. M. M.: Genetic impairment of folate metabolism regulates cortical interneurons and social behavior. Frontiers in Neuroscience 17, 1203262 (2023)

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11.

Journal Article

Chen, C.; de Hoz, L.: The perceptual categorization of multidimensional stimuli is hierarchically organized. iScience 26 (6), 106941 (2023)

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12.

Journal Article

Depp, C.; Sun, T.; Sasmita, A. O.; Spieth, L.; Berghoff, S. A.; Nazarenko, T.; Overhoff, K.; Steixner-Kumar, A. A.; Subramanian, S.; Arinrad, S. et al.; Ruhwedel, T.; Möbius, W.; Göbbels, S.; Saher, G.; Werner, H. B.; Damkou, A.; Zampar, S.; Wirths, O.; Thalmann, M.; Simons, M.; Saito, T.; Saido, T.; Krueger-Burg, D.; Kawaguchi, R.; Willem, M.; Haass, C.; Geschwind, D.; Ehrenreich, H.; Stassart, R. M.; Nave, K.-A.: Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease. Nature 618, pp. 349 - 357 (2023)

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13.

Journal Article

Schilling, S.; Pradhan, A.; Heesch, A.; Helbig, A.; Blennow, K.; Koch, C.; Bertgen, L.; Koo, E. H.; Brinkmalm, G.; Zetterberg, H. et al.; Kins, S.; Eggert, S.: Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity. Acta Neuropathologica Communications 11, 87 (2023)

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14.

Journal Article

Krämer-Albers, E.-M.; Werner, H. B.: Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles. Nature Reviews Neuroscience 24, pp. 474 - 486 (2023)

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15.

Journal Article

Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian Oocytes Store mRNAs in a Mitochondria-Associated Membraneless Compartment. Obstetrical & Gynecological Survey 78 (5), pp. 280 - 281 (2023)

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16.

Journal Article

Pour, N. J. A.; Zabihi-Mahmoudabadi, H.; Ebrahimi, R.; Yekaninejad, M. S.; Hashemnia, S. M. R.; Meshkani, R.; Emamgholipour, S.: Principal component analysis of adipose tissue gene expression of lipogenic and adipogenic factors in obesity. BMC Endocrine Disorders 23 (1), 94 (2023)

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17.

Journal Article

Chatterjee, M.; Özdemir, S.; Kunadt, M.; Koel-Simmelink, M.; Boiten, W.; Piepkorn, L.; Pham, T. V.; Chiasserini, D.; Piersma, S. R.; Knol, J. C. et al.; Möbius, W.; Mollenhauer, B.; van der Flier, W. M.; Jimenez, C. R.; Teunissen, C. E.; Jahn, O.; Schneider, A.: C1q is increased in cerebrospinal fluid-derived extracellular vesicles in Alzheimer's disease: A multi-cohort proteomics and immuno-assay validation study. Alzheimer's & Dementia, in press (2023)

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18.

Journal Article

Kapell, H.; Fazio, L.; Dyckow, J.; Schwarz, S.; Cruz-Herranz, A.; Mayer, C.; Campos, J.; D´Este, E.; Möbius, W.; Cordano, C. et al.; Pröbstel, A.-K.; Gharagozloo, M.; Zulji, A.; Naik, V. N.; Delank, A.-K.; Cerina, M.; Müntefering, T.; Lerma-Martin, C.; Sonner, J. K.; Sin, J. H.; Disse, P.; Rychlik, N.; Sabeur, K.; Chavali, M.; Srivastava, R.; Heidenreich, M.; Fitzgerald, K. C.; Seebohm, G.; Stadelmann, C.; Hemmer, B.; Platten, M.; Jentsch, T. J.; Engelhardt, M.; Budde, T.; Nave, K.-A.; Calabresi, P. A.; Friese, M. A.; Green, A. J.; Acuna, C.; Rowitch, D. H.; Meuth, S. G.; Schirmer, L.: Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination. The Journal of Clinical Investigation 133 (7), e164223 (2023)

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19.

Journal Article

van den Bosch, A. M. R.; Hümmert, S.; Steyer, A.; Ruhwedel, T.; Hamann, J.; Smolders, J.; Nave, K.-A.; Stadelmann, C.; Kole, M. H. P.; Möbius, W. et al.; Huitinga, I.: Ultrastructural Axon–Myelin Unit Alterations in Multiple Sclerosis Correlate with Inflammation. Annals of Neurology 93 (4), pp. 856 - 870 (2023)

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20.

Journal Article

Arinrad, S.; Depp, C.; Siems, S. B.; Sasmita, A. O.; Eichel, M. A.; Ronnenberg, A.; Hammerschmidt, K.; Lüders, K. A.; Werner, H. B.; Ehrenreich, H. et al.; Nave, K.-A.: Isolated catatonia-like executive dysfunction in mice with forebrain-specific loss of myelin integrity. eLife 12, e70792 (2023)

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21.

Journal Article

Bohmbach, K.; Henneberger, C.; Hirrlinger, J.: Astrocytes in memory formation and maintenance. Essays in Biochemistry 67 (1), pp. 107 - 117 (2023)

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22.

Journal Article

Schoknecht, K.; Hirrlinger, J.; Eilers, J.: Transient astrocytic accumulation of fluorescein during spreading depolarizations. Neurobiology of Disease 178, 106026 (2023)

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23.

Journal Article

Steyer, A. M.; Buscham, T. J.; Lorenz, C.; Hümmert, S.; Eichel‐Vogel, M. A.; Schadt, L. C.; Edgar, J. M.; Köster, S.; Möbius, W.; Nave, K.-A. et al.; Werner, H. B.: Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag. Glia 71 (3), pp. 509 - 523 (2023)

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24.

Journal Article

Daguano Gastaldi, V.; Wilke, J. B. H.; Weidinger, C. A.; Walter, C.; Barnkothe, N.; Teegen, B.; Luessi, F.; Stöcker, W.; Lühder, F.; Begemann, M. et al.; Zipp, F.; Nave, K.-A.; Ehrenreich, H.: Factors predisposing to humoral autoimmunity against brain-antigens in health and disease Analysis of 49 autoantibodies in over 7000 subjects. Brain, Behavior, and Immunity 108, pp. 135 - 147 (2023)

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25.

Journal Article

Köhler, S.; Winkler, U.; Junge, T.; Lippmann, K.; Eilers, J.; Hirrlinger, J.: Gray and white matter astrocytes differ in basal metabolism but respond similarly to neuronal activity. Glia 71 (2), pp. 229 - 244 (2023)

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26.

Journal Article

Schoger, E.; Bleckwedel, F.; Germena, G.; Rocha, C.; Tucholla, P.; Sobitov, I.; Möbius, W.; Sitte, M.; Lenz, C.; Samak, M. et al.; Hinkel, R.; Varga, Z. V.; Giricz, Z.; Salinas, G.; Gross, J. C.; Zelarayan, L. C.: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling. Communications Biology 6 (1), 79 (2023)

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27.

Journal Article

Djannatian, M.; Radha, S.; Weikert, U.; Safaiyan, S.; Wrede, C.; Deichsel, C.; Kislinger, G.; Rhomberg, A.; Ruhwedel, T.; Campbell, D. S. et al.; van Ham, T.; Schmid, B.; Hegermann, J.; Möbius, W.; Schifferer, M.; Simons, M.: Myelination generates aberrant ultrastructure that is resolved by microglia. Journal of Cell Biology 222 (3), e202204010 (2023)

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28.

Journal Article

Oke, Y.; Miwakeichi, F.; Oku, Y.; Hirrlinger, J.; Hülsmann, S.: Cell types and synchronous-activity patterns of inspiratory neurons in the preBötzinger complex of mouse medullary slices during early postnatal development. Scientific Reports 13, 586 (2023)

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29.

Journal Article

Martens, A.-K.; Erwig, M. S.; Patzig, J.; Fledrich, R.; Füchtbauer, E.; Werner, H. B.: Targeted inactivation of the Septin2 and Septin9 genes in myelinating Schwann cells of mice. Cytoskeleton 80 (7-8), pp. 290 - 302 (2023)

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30.

Journal Article

Petersen, G. C.; Amirkhizi, M.; Brockmann, K.; Dibaj, P.: Hemifacial spasm through changes of cerebrospinal fluid pressure in idiopathic intracranial hypertension. Baylor University Medical Center Proceedings 36 (1), pp. 114 - 115 (2023)

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31.

Journal Article

Brás, I. C.; Khani, M. H.; Vasili, E.; Möbius, W.; Riedel, D.; Parfentev, I.; Gerhardt, E.; Fahlbusch, C.; Urlaub, H.; Zweckstetter, M. et al.; Gollisch, T.; Outeiro, T. F.: Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity. Journal of Parkinson's Disease: JPD 12, pp. 2397 - 2422 (2022)

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32.

Journal Article

Lutomska, L. M.; Miok, V.; Krahmer, N.; García, I. G.; Gruber, T.; Le Thuc, O.; Murat, C. D.; Legutko, B.; Sterr, M.; Saher, G. et al.; Lickert, H.; Müller, T. D.; Ussar, S.; Tschöp, M. H.; Lutter, D.; García-Cáceres, C.: Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner. Glia 70 (11), pp. 2062 - 2078 (2022)

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33.

Journal Article

Busch, L.; Eggert, S.; Endres, K.; Bufe, B.: The Hidden Role of Non-Canonical Amyloid beta Isoforms in Alzheimer's Disease. Cells 11 (21), 3421 (2022)

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34.

Journal Article

Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment. Science 378 (6617), eabq4835 (2022)

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35.

Journal Article

Düking, T.; Spieth, L.; Berghoff, S. A.; Piepkorn, L.; Schmidke, A. M.; Mitkovski, M.; Kannaiyan, N.; Hosang, L.; Scholz, P.; Shaib, A. H. et al.; Schneider, L. V.; Hesse, D.; Ruhwedel, T.; Sun, T.; Linhoff, L.; Trevisiol, A.; Köhler, S.; Pastor, A. M.; Misgeld, T.; Sereda, M.; Hassouna, I.; Rossner, M. J.; Odoardi, F.; Ischebeck, T.; de Hoz, L.; Hirrlinger, J.; Jahn, O.; Saher, G.: Ketogenic diet uncovers differential metabolic plasticity of brain cells. Science Advances 8 (37), eabo7639 (2022)

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36.

Journal Article

Linnemannstöns, K.; Karuna M, P.; Witte, L.; Choezom, D.; Honemann-Capito, M.; Lagurin, A. S.; Schmidt, C. V.; Shrikhande, S.; Steinmetz, L.-K.; Möbius, W. et al.; Lenz, C.; Gross, J. C.: Microscopic and biochemical monitoring of endosomal trafficking and extracellular vesicle secretion in an endogenous in vivo model. Journal of extracellular vesicles 11 (9), 12263 (2022)

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37.

Journal Article

Jablonska, B.; Adams, K. L.; Kratimenos, P.; Li, Z.; Strickland, E.; Haydar, T. F.; Kusch, K.; Nave, K.-A.; Gallo, V.: Sirt2 promotes white matter oligodendrogenesis during development and in models of neonatal hypoxia. Nature Communications 13, 4771 (2022)

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38.

Journal Article

Schepanski, S.; Chini, M.; Sternemann, V.; Urbschat, C.; Thiele, K.; Sun, T.; Zhao, Y.; Poburski, M.; Woestemeier, A.; Thieme, M.-T. et al.; Zazara, D. E.; Alawi, M.; Fischer, N.; Heeren, J.; Vladimirov, N.; Woehler, A.; Puelles, V. G.; Bonn, S.; Gagliani, N.; Hanganu-Opatz, I. L.; Arck, P. C.: Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice. Nature Communications 13 (1), 4571 (2022)

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39.

Journal Article

Hirrlinger, J.; Nimmerjahn, A.: A perspective on astrocyte regulation of neural circuit function and animal behavior. Glia 70 (8), pp. 1554 - 1580 (2022)

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40.

Journal Article

Paes de Faria, J.; Vale-Silva, R. S.; Fässler, R.; Werner, H. B.; Relvas, J. B.: Pinch2 regulates myelination in the mouse central nervous system. Development 149 (13), dev200597 (2022)

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41.

Journal Article

Garg, P.; Maass, F.; Sundaram, S. M.; Mollenhauer, B.; Mahajani, S.; van Riesen, C.; Kuegler, S.; Baehr, M.: The relevance of synuclein autoantibodies as a biomarker for Parkinson's disease. Molecular and Cellular Neuroscience 121, 103746 (2022)

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Journal Article

Gargareta, V.-I.; Reuschenbach, J.; Siems, S. B.; Sun, T.; Piepkorn, L.; Mangana, C.; Späte, E.; Goebbels, S.; Huitinga, I.; Möbius, W. et al.; Nave, K.-A.; Jahn, O.; Werner, H. B.: Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. eLife 11, e77019 (2022)

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43.

Journal Article

Berghoff, S. A.; Spieth, L.; Saher, G.: Local cholesterol metabolism orchestrates remyelination. Trends in Neurosciences 45 (4), pp. 272 - 283 (2022)

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44.

Journal Article

Heo, D.; Ling, J. P.; Molina-Castro, G. C.; Langseth, A. J.; Waisman, A.; Nave, K.-A.; Möbius, W.; Wong, P. C.; Bergles, D. E.: Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43. eLife 11, e75230 (2022)

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45.

Journal Article

Buscham, T. J.; Eichel-Vogel, M. A.; Steyer, A. M.; Jahn, O.; Strenzke, N.; Dardawal, R.; Memhave, T. R.; Siems, S. B.; Müller, C.; Meschkat, M. et al.; Sun, T.; Ruhwedel, T.; Möbius, W.; Krämer-Albers, E.-M.; Boretius, S.; Nave, K.-A.; Werner, H. B.: Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5. eLife 11, e75523 (2022)

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46.

Journal Article

Haupt, L. P.; Rebs, S.; Maurer, W.; Huebscher, D.; Tiburcy, M.; Pabel, S.; Maus, A.; Koehne, S.; Tappu, R.; Haas, J. et al.; Li, Y.; Sasse, A.; Santos, C. C. X.; Dressel, R.; Wojnowski, L.; Bunt, G.; Moebius, W.; Shah, A. M.; Meder, B.; Wollnik, B.; Sossalla, S.; Hasenfuss, G.; Streckfuss-Boemeke, K.: Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients. Basic Research in Cardiology 117 (1), 13 (2022)

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47.

Journal Article

Hösli, L.; Binini, N.; Ferrari, K. D.; Thieren, L.; Looser, Z. J.; Zuend, M.; Zanker, H. S.; Berry, S.; Holub, M.; Möbius, W. et al.; Ruhwedel, T.; Nave, K.-A.; Giaume, C.; Weber, B.; Saab, A. S.: Decoupling astrocytes in adult mice impairs synaptic plasticity and spatial learning. Cell Reports 38 (10), 110484 (2022)

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48.

Journal Article

Meschkat, M.; Steyer, A. M.; Weil, M.-T.; Kusch, K.; Jahn, O.; Piepkorn, L.; Agüi-Gonzalez, P.; Phan, N. T. N.; Ruhwedel, T.; Sadowski, B. et al.; Rizzoli, S. O.; Werner, H. B.; Ehrenreich, H.; Nave, K.-A.; Möbius, W.: White matter integrity in mice requires continuous myelin synthesis at the inner tongue. Nature Communications 13, 1163 (2022)

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49.

Journal Article

So, C.; Menelaou, K.; Uraji, J.; Harasimov, K.; Steyer, A. M.; Seres, K. B.; Bucevičius, J.; Lukinavicius, G.; Möbius, W.; Sibold, C. et al.; Tandler-Schneider, A.; Eckel, H.; Moltrecht, R.; Blayney, M.; Elder, K.; Schuh, M.: Mechanism of spindle pole organization and instability in human oocytes. Science 375 (6581), eabj3944 (2022)

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Rivellini, C.; Porrello, E.; Dina, G.; Mrakic-Sposta, S.; Vezzoli, A.; Bacigaluppi, M.; Gullotta, G. S.; Chaabane, L.; Leocani, L.; Marenna, S. et al.; Colombo, E.; Farina, C.; Newcombe, J.; Nave, K.-A.; Pardi, R.; Quattrini, A.; Previtali, S. C.: JAB1 deletion in oligodendrocytes causes senescence-induced inflammation and neurodegeneration in mice. Journal of Clinical Investigation 132 (3), e145071 (2022)

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Publications (Department Neurogenetics)

Journal Article (661)