Selected publications

Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L.; Schlaphoff, L.; Depp, C.; Düking, T.; Winchenbach, J.; Neuber, J.; Ewers, D. et al.; Scholz, P.; van der Meer, F.; Cantuti-Castelvetri, L.; Sasmita, A. O.; Meschkat, M.; Ruhwedel, T.; Möbius, W.; Sankowski, R.; Prinz, M.; Huitinga, I.; Sereda, M. W.; Odoardi, F.; Ischebeck, T.; Simons, M.; Stadelmann-Nessler, C.; Edgar, J. M.; Nave, K.-A.; Saher, G.: Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis. Nature Neuroscience 24, pp. 47 - 60 (2021)

Trevisiol, A.; Kusch, K.; Steyer, A. M.; Gregor, I.; Nardis, C.; Winkler, U.; Köhler, S.; Restrepo, A.; Möbius, W.; Werner, H. B. et al.; Nave, K.-A.; Hirrlinger, J.: Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia. PLoS Biology 18 (11), e3000943 (2020)

Moore, S.; Meschkat, M.; Ruhwedel, T.; Trevisiol, A.; Tzvetanova, I.; Battefeld, A.; Kusch, K.; Kole, M. H. P.; Strenzke, N.; Möbius, W. et al.; de Hoz, L.; Nave, K.-A.: A role of oligodendrocytes in information processing. Nature Communications 11 (1), 5497 (2020)

Werner, H. B.; Nave, K. A.: Enhanced actin dynamics: A therapeutic strategy for axonal regeneration? Neuron 103 (6), pp. 949 - 950 (2019)

Janova, H.; Arinrad, S.; Balmuth, E.; Mitjans, M.; Hertel, J.; Habes, M.; Bittner, R. A.; Pan, H.; Goebbels, S.; Begemann, M. et al.; Gerwig, U. C.; Langner, S.; Werner, H. B.; Kittel-Schneider, S.; Homuth, G.; Davatzikos, C.; Völzke, H.; West, B. L.; Reif, A.; Grabe, H. J.; Boretius, S.; Ehrenreich, H.; Nave, K.-A.: Microglia ablation alleviates myelin-associated catatonic signs in mice. The Journal of Clinical Investigation 128 (2), pp. 734 - 745 (2018)

Saab, A. S.; Nave, K.-A.: Myelin dynamics: protecting and shaping neuronal functions. Current Opinion in Neurobiology 47, pp. 104 - 112 (2017)

Trevisiol, A.; Saab, A. S.; Winkler, U.; Marx, G.; Imamura, H.; Möbius, W.; Kusch, K.; Nave, K.-A.; Hirrlinger, J.: Monitoring ATP dynamics in electrically active white matter tracts. eLife 6, e24241 (2017)

Goebbels, S.; Wieser, G. L.; Pieper, A.; Spitzer, S.; Weege, B.; Yan, K.; Edgar, J. M.; Yagensky, O.; Wichert, S. P.; Agarwal, A. et al.; Karram, K.; Renier, N.; Tessier-Lavigne, M.; Rossner, M. J.; Káradóttir, R. T.; Nave, K.-A.: A neuronal PI(3,4,5)P₃-dependent program of oligodendrocyte precursor recruitment and myelination. Nature Neuroscience 20 (1), pp. 10 - 15 (2017)

Snaidero, N.; Velte, C.; Myllykoski, M.; Raasakka, A.; Ignatev, A.; Werner, H. B.; Erwig, M. S.; Möbius, W.; Kursula, P.; Nave, K.-A. et al.; Simons, M.: Antagonistic functions of MBP and CNP establish cytosolic channels in CNS myelin. Cell Reports 18 (2), pp. 314 - 323 (2017)

Quintes, S.; Brinkmann, B. G.; Ebert, M.; Fröb, F.; Kungl, T.; Arlt, F. A.; Tarabykin, V.; Huylebroeck, D.; Meijer, D.; Suter, U. et al.; Wegner, M.; Sereda, M. W.; Nave, K.-A.: Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair. Nature Neuroscience 19 (8), pp. 1050 - 1059 (2016)

Saab, A. S.; Tzvetanova, I. D.; Trevisiol, A.; Baltan, S.; Dibaj, P.; Kusch, K.; Möbius, W.; Goetze, B.; Jahn, H. M.; Huang, W. et al.; Steffens, H.; Schomburg, E. D.; Pérez-Samartín, A.; Pérez-Cerdá, F.; Bakhtiari, D.; Matute, C.; Löwel, S.; Griesinger, C.; Hirrlinger, J.; Kirchhoff, F.; Nave, K.-A.: Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism. Neuron 91 (1), pp. 119 - 132 (2016)

Simons, M.; Nave, K.-A.: Oligodendrocytes: myelination and axonal support. Cold Spring Harbor Perspectives in Biology 8 (1), a020479 (2015)

Nave, K.-A.; Werner, H. B.: Myelination of the Nervous System: Mechanisms and Functions. Annual Review of Cell and Developmental Biology 30, pp. 503 - 533 (2014)

Fledrich, R.; Stassart, R. M.; Klink, A.; Rasch, L. M.; Prukop, T.; Haag, L.; Czesnik, D.; Kungl, T.; Abdelaal, T. A. M.; Keric, N. et al.; Stadelmann, C.; Brück, W.; Nave, K.-A.; Sereda, M. W.: Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A. Nature Medicine 20 (9), pp. 1055 - 1061 (2014)

Mei, L.; Nave, K.-A.: Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases. Neuron 83 (1), pp. 27 - 49 (2014)

Nave, K.-A.; Ehrenreich, H.: Myelination and oligodendrocyte functions in psychiatric diseases. JAMA Psychiatry 71 (5), pp. 582 - 584 (2014)

Snaidero, N.; Möbius, W.; Czopka, T.; Hekking, L. H. P.; Mathisen, C.; Verkleij, D.; Goebbels, S.; Edgar, J.; Merkler, D.; Lyons, D. A. et al.; Nave, K.-A.; Simons, M.: Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue. Cell 156 (1-2), pp. 277 - 290 (2014)

Saab, A. S.; Tzvetanova, I. D.; Nave, K.-A.: The role of myelin and oligodendrocytes in axonal energy metabolism. Current Opinion in Neurobiology 23 (6), pp. 1065 - 1072 (2013)

Stassart, R. M.; Fledrich, R.; Velanac, V.; Brinkmann, B. G.; Schwab, M. H.; Meijer, D.; Sereda, M. W.; Nave, K.-A.: A role for Schwann cell-derived neuregulin-1 in remyelination. Nature Neuroscience 16 (1), pp. 48 - 54 (2013)

Saher, G.; Rudolphi, F.; Corthals, K.; Ruhwedel, T.; Schmidt, K.-F.; Löwel, S.; Dibaj, P.; Barrette, B.; Möbius, W.; Nave, K.-A.: Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet. Nature Medicine 18 (7), pp. 1130 - 1135 (2012)