Publications (Department Neurogenetics)

Belvindrah, R.; Graus-Porta, D.; Goebbels, S.; Nave, K.-A.; Mueller, U.: β1 Integrins in Radial Glia But Not in Migrating Neurons Are Essential for the Formation of Cell Layers in the Cerebral Cortex. The Journal of Neuroscience 27 (50), pp. 13854 - 13865 (2007)

Dhaunchak, A.-S.; Nave, K.-A.: A common mechanism of PLP/DM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher disease. Proceedings of the National Academy of Sciences of the United States of America 104 (45), pp. 17813 - 17818 (2007)

Krämer-Albers, E.-M.; Bretz, N.; Tenzer, S.; Winterstein, C.; Möbius, W.; Berger, H.; Nave, K.-A.; Schild, H.; Trotter, J.: Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Proteomics Clinical Applications 1 (11), pp. 1446 - 1461 (2007)

Leder, C.; Schwab, N.; Ip, C. W.; Kroner, A.; Nave, K.-A.; Dornmair, K.; Martini, R.; Wiendl, H.: Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice. Molecular and Cellular Neuroscience 36 (3), pp. 416 - 424 (2007)

Newrzella, D.; Pahlavan, P. S.; Krüger, C.; Boehm, C.; Sorgenfrei, O.; Schröck, H.; Eisenhardt, G.; Bischoff, N.; Vogt, G.; Wafzig, O. et al.; Rossner, M. J.; Maurer, M. H.; Hiemisch, H.; Bach, A.; Kuschinsky, W.; Schneider, A.: The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia. BMC Genomics 8, 370 (2007)

Winter, S. M.; Hirrlinger, J.; Kirchhoff, F.; Hülsmann, S.: Transgenic expression of fluorescent proteins in respiratory neurons. Respiratory Physiology & Neurobiology 159 (1), pp. 108 - 114 (2007)

Ehrenreich, H.; Fischer, B.; Norra, C.; Schellenberger, F.; Stender, N.; Stiefel, M.; Sirén, A.-L.; Paulus, W.; Nave, K.-A.; Gold, R. et al.; Bartels, C.: Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis. Brain 130 (10), pp. 2577 - 2588 (2007)

Wu, Q.; Butzkueven, H.; Gresle, M.; Kirchhoff, F.; Friedhuber, A.; Yang, Q.; Hong, W.; Fang, K.; Lei, H.; Egan, G. F. et al.; Kilpatrick, T. J.: MR diffusion changes correlate with ultra-structurally defined axonal degeneration in murine optic nerve. NeuroImage 37 (4), pp. 1138 - 1147 (2007)

Kassmann, C. M.; Lappe-Siefke, C.; Baes, M.; Brugger, B.; Mildner, A.; Werner, H. B.; Natt, O.; Michaelis, T.; Prinz, M.; Frahm, J. et al.; Nave, K.-A.: Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nature Genetics 39 (8), pp. 969 - 976 (2007)

Nadrigny, F.; Li, D.; Kemnitz, K.; Ropert, N.; Koulakoff, A.; Rudolph, S.; Vitali, M.; Giaume, C.; Kirchhoff, F.; Oheim, M.: Systematic colocalization errors between acridine orange and EGFP in astrocyte vesicular organelles. Biophysical Journal 93 (3), pp. 969 - 980 (2007)

Nave, K.-A.; Sereda, M. W.; Ehrenreich, H.: Mechanisms of Disease: inherited demyelinating neuropathies - from basic to clinical research. Nature Clinical Practice Neurology 3 (8), pp. 453 - 464 (2007)

He, Y.; Dupree, J.; Wang, J.; Sandoval, J.; Li, J.; Liu, H.; Shi, Y.; Nave, K.-A.; Casaccia-Bonnefil, P.: The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron 55 (2), pp. 217 - 230 (2007)

Werner, H. B.; Kuhlmann, K.; Shen, S.; Uecker, M.; Schardt, A.; Dimova, K.; Orfaniotou, F.; Dhaunchak, A.; Brinkmann, B. G.; Möbius, W. et al.; Guarente, L.; Casaccia-Bonnefil, P.; Jahn, O.; Nave, K.-A.: Proteolipid Protein Is Required for Transport of Sirtuin 2 into CNS Myelin. The Journal of Neuroscience 27 (29), pp. 7717 - 7730 (2007)

Giaume, C.; Kirchhoff, F.; Matute, C.; Reichenbach, A.; Verkhratsky, A.: Glia: the fulcrum of brain diseases. Cell Death and Differentiation 14 (7), pp. 1324 - 1335 (2007)

Benninger, Y.; Thurnherr, T.; Pereira, J. A.; Wu, X.; Chrostek-Grashoff, A.; Herzog, D.; Nave, K.-A.; Franklin, R. J. M.; Meijer, D.; Brakebusch, C. et al.; Suter, U.; Relvas, J. B.: Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. Journal of Cell Biology 177 (6), pp. 1051 - 1061 (2007)

Chvatal, A.; Anderova, M.; Kirchhoff, F.: Three-dimensional confocal morphometry - a new approach for studying dynamic changes in cell morphology in brain slices. Journal of Anatomy 210 (6), pp. 671 - 683 (2007)

Verkhratsky, A.; Kirchhoff, F.: Glutamate-mediated neuronal-glial transmission. Journal of Anatomy 210 (6), pp. 651 - 660 (2007)

Wigley, R.; Hamilton, N.; Nishiyama, A.; Kirchhoff, F.; Butt, A. M.: Morphological and physiological interactions of NG2-glia with astrocytes and neurons. Journal of Anatomy 210 (6), pp. 661 - 670 (2007)

Ivanova, N.; Claeys, K. G.; Deconinck, T.; Litvinenko, I.; Jordanova, A.; Auer-Grumbach, M.; Haberlova, J.; Löfgren, A.; Smeyers, G.; Nelis, E. et al.; Mercelis, R.; Plecko, B.; Priller, J.; Zamecnik, J.; Ceulemans, B.; Erichsen, A. K.; Björck, E.; Nicholson, G.; Sereda, M. W.; Seeman, P.; Kremensky, I.; Mitev, V.; De Jonghe, P.: Hereditary spastic paraplegia 3A associated with axonal neuropathy. Archives of Neurology 64 (5), pp. 706 - 713 (2007)

Karim, S. A.; Barrie, J. A.; McCulloch, M. C.; Montague, P.; Edgar, J. M.; Kirkham, D.; Anderson, T. J.; Nave, K.-A.; Griffiths, I. R.; Mclaughlin, M.: PLP overexpression perturbs myelin protein composition and myelination in a mouse model of Pelizaeus-Merzbacher disease. Glia 55 (4), pp. 341 - 351 (2007)

Zeger, M.; Popken, G.; Zhang, J.; Xuan, S.; Lu, Q. R.; Schwab, M. H.; Nave, K.-A.; Rowitch, D.; D'Ercole, A. J.; Ye, P.: Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination. Glia 55 (4), pp. 400 - 411 (2007)

Oertel, J.; Villmann, C.; Kettenmann, H.; Kirchhoff, F.; Becker, C.-M.: A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology: Assembly into heteromeric receptor complexes. Journal of Biological Chemistry 282 (5), pp. 2798 - 2807 (2007)

Chvatal, A.; Anderova, M.; Hock, M.; Prajerova, I.; Neprasova, H.; Chvatal, V.; Kirchhoff, F.; Sykova, E.: Three-dimensional confocal morphometry reveals structural changes in astrocyte morphology in situ. Journal of Neuroscience Research 85 (2), pp. 260 - 271 (2007)

Verkhratsky, A.; Kirchhoff, F.: NMDA receptors in glia. The Neuroscientist 13 (1), pp. 28 - 37 (2007)

Grove, M.; Komiyama, N. H.; Nave, K.-A.; Grant, S. G.; Sherman, D. L.; Brophy, P. J.: FAK is required for axonal sorting by Schwann cells. Journal of Cell Biology 176 (3), pp. 277 - 282 (2007)

Fünfschilling, U.; Saher, G.; Xiao, L.; Möbius, W.; Nave, K.-A.: Survival of adult neurons lacking cholesterol synthesis in vivo. BMC Neuroscience 8, 1 (2007)

Ip, C. W.; Kroner, A.; Crocker, P. R.; Nave, K.-A.; Martini, R.: Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice. Neurobiology of Disease 25 (1), pp. 105 - 111 (2007)

Kippert, A.; Trajkovic, K.; Rajendran, L.; Ries, J.; Simons, M.: Rho regulates membrane transport in the endocytic pathway to control plasma membrane specialization in oligodendroglial cells. Journal of Neuroscience 27 (13), pp. 3560 - 3570 (2007)

Meyer zu Hörste, G.; Prukop, T.; Liebetanz, D.; Möbius, W.; Nave, K.-A.; Sereda, M. W.: Antiprogesterone therapy uncouples axonal loss from demyelination in a transgenic rat model of CMT1A neuropathy. Annals of Neurology 61 (1), pp. 61 - 72 (2007)