Journal Article (280)
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Journal Article
17 (2), pp. 216 - 222 (2010)
Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nature Structural and Molecular Biology 102.
Journal Article
29, pp. 749 - 760 (2010)
The intronic splicing code: Multiple factors involved in ATM pseudoexon definition. The EMBO Journal 103.
Journal Article
82 (7), pp. 2784 - 2796 (2010)
Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring. Analytical Chemistry 104.
Journal Article
29, pp. 4172 - 4184 (2010)
Functional organization of the Sm core in the crystal structure of human U1 snRNP. EMBO Journal 105.
Journal Article
16 (12), pp. 1237 - 1243 (2009)
Reconstitution of both steps of S. cerevisiae splicing with purified spliceosomal components. Nature Structural and Molecular Biology 106.
Journal Article
37 (20), e133 (2009)
In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic Acids Research 107.
Journal Article
29 (13), pp. 3700 - 3709 (2009)
HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in Caenorhabditis elegans germ line. Molecular and Cellular Biology 108.
Journal Article
28, pp. 2283 - 2292 (2009)
Exon, intron and splice site locations in the spliceosomal B complex. EMBO Journal 109.
Journal Article
136 (4), pp. 701 - 718 (2009)
The spliceosome: design principles of a dynamic RNP machine. Cell 110.
Journal Article
36 (4), pp. 593 - 608 (2009)
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Molecular Cell 111.
Journal Article
385 (2), pp. 531 - 541 (2009)
Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. Journal of Molecular Biology 112.
Journal Article
60, pp. 2418 - 2427 (2009)
Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells. Arthritis & Rheumatism 113.
Journal Article
29 (1), pp. 281 - 301 (2009)
Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Molecular and Cellular Biology 114.
Journal Article
8, pp. 2461 - 2473 (2009)
Proline-rich sequence recognition I: Marking GYF and WW domain assembly sites in early spliceosomal complexes. Molecular and Cellular Proteomics 115.
Journal Article
15 (1), pp. 153 - 175 (2009)
Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA 116.
Journal Article
19, pp. 96 - 102 (2009)
Structural mapping of spliceosomes by electron microscopy. Current Opinion in Structural Biology 117.
Journal Article
35 (4), pp. 454 - 466 (2009)
Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Molecular Cell 118.
Journal Article
135 (7), pp. 1224 - 1236 (2008)
Dynamic regulation of alternative splicing by silencers that modulate 5´ splice site competition. Cell 119.
Journal Article
14, pp. 2528 - 2537 (2008)
Structure of yeast U6 snRNPs: arrangement of Prp24p and the LSm complex as revealed by electron microscopy. RNA 120.
Journal Article
283 (47), pp. 32317 - 32327 (2008)
An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex. The Journal of Biological Chemistry 121.
Journal Article
15 (11), pp. 1206 - 1212 (2008)
Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Nature Structural and Molecular Biology 122.
Journal Article
27 (21), pp. 2929 - 2940 (2008)
Structure and function of an RNase H domain at the heart of the spliceosome. The EMBO Journal 123.
Journal Article
14 (8), pp. 1532 - 1538 (2008)
3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins. RNA 124.
Journal Article
105, pp. 8655 - 8660 (2008)
Minor spliceosome components are predominantly localized in the nucleus. Proceedings of the National Academy of Sciences of the United States of America 125.
Journal Article
28 (10), pp. 3386 - 3400 (2008)
Abnormal sympathoadrenal development and systemic hypotension in PHD3–/– mice. Molecular and Cellular Biology 126.
Journal Article
15 (5), pp. 435 - 443 (2008)
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nature Structural & Molecular Biology 127.
Journal Article
28 (10), pp. 3548 - 3560 (2008)
The U11-48K protein contacts the 5' splice site of U12-Type introns and the U11-59K protein. Molecular and Cellular Biology 128.
Journal Article
452 (7189), pp. 846 - 850 (2008)
Isolation of an active step I spliceosome and composition of its RNP core. Nature 129.
Journal Article
5 (1), pp. 53 - 55 (2008)
GraFix: sample preparation for single-particle electron cryomicroscopy. Nature Methods 130.
Journal Article
3 (10), e201, pp. 2019 - 2031 (2007)
A stochastic view of spliceosome assembly and recycling in the nucleus. PLoS Computational Biology 131.
Journal Article
27 (20), pp. 7018 - 7027 (2007)
Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis. Molecular and Cellular Biology 132.
Journal Article
35 (15), e95 (2007)
Improved identification of enriched peptide–RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry. Nucleic Acids Research 133.
Journal Article
369 (4), pp. 902 - 908 (2007)
Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). Journal of Molecular Biology 134.
Journal Article
316, 5821, pp. 115 - 120 (2007)
Binding of the human Prp31 nop domain to a composite RNA-protein platform in U4 snRNP. Science 135.
Journal Article
26 (6), pp. 1737 - 1748 (2007)
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. The EMBO Journal 136.
Journal Article
25 (4), pp. 615 - 624 (2007)
Structure of a multipartite protein-protein interaction domain in splicing factor Prp8 and its link to retinitis pigmentosa. Molecular Cell 137.
Journal Article
25 (3), pp. 399 - 411 (2007)
The 5′ end of U2 snRNA is in close proximity to U1 and functional sites of the Pre-mRNA in early spliceosomal complexes. Molecular Cell 138.
Journal Article
14 (2), pp. 286 - 295 (2007)
Different modes of translation for hid, grim and sickle mRNAs in Drosophila. Cell Death and Differentiation 139.
Journal Article
13, pp. 116 - 128 (2007)
Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA 140.
Journal Article
24 (2), pp. 267 - 278 (2006)
Organization of Core Spliceosomal Components U5 snRNA Loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as Revealed by Electron Cryomicroscopy. Molecular Cell 141.
Journal Article
281 (38), pp. 28278 - 28286 (2006)
RNA structural requirements for the association of the spliceosomal hPrp31 protein with the U4 and U4atac small nuclear ribonucleoprotein. Journal of Biological Chemistry 142.
Journal Article
103 (31), pp. 11440 - 11445 (2006)
Macromolecular-scale resolution in biological fluorescence microscopy. Proceedings of the National Academy of Sciences of the United States of America 143.
Journal Article
12 (8), pp. 1494 - 1504 (2006)
Identification, cloning and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA 144.
Journal Article
26 (14), pp. 5528 - 5543 (2006)
Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Molecular and Cellular Biology 145.
Journal Article
17, pp. 3221 - 3231 (2006)
Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies. Molecular Biology of the Cell 146.
Journal Article
26 (13), pp. 5146 - 5154 (2006)
Protein-protein and protein-RNA contacts both contribute to the 15.5K-mediated assembly of the U4/U6 snRNP and the box C/D snoRNPs. Molecular and Cellular Biology 147.
Journal Article
25 (11), pp. 2475 - 2486 (2006)
Proximity of conserved U6 and U2 snRNA elements to the 5' splice site region in activated spliceosomes. EMBO Journal 148.
Journal Article
107 (8), pp. 3229 - 3234 (2006)
U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Blood 149.
Journal Article
26 (7), pp. 2803 - 2816 (2006)
U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes. Molecular and Cellular Biology 150.
Journal Article
12 (3), pp. 410 - 425 (2006)
Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA