Publications

Pawellek, A.; McElroy, S.; Samatov, T.; Mitchell, L.; Woodland, A.; Ryder, U.; Gray, D.; Lührmann, R.; Lamond, A.: Identification of small molecule inhibitors of pre-mRNA splicing. The Journal of Biological Chemistry 289 (50), pp. 34683 - 34698 (2014)

Alló, M.; Agirre, E.; Bessonov, S.; Bertucci, P.; Acuña, L. G.; Buggiano, V.; Bellora, N.; Singh, B.; Petrilloa, E.; Blaustein, M. et al.; Miñana, B.; Dujardin, G.; Pozzi, B.; Pelisch, F.; Bechara, E.; Agafonov, D. E.; Srebrow, A.; Lührmann, R.; Valcárcel, J.; Eyras, E.; Kornblihtt, A. R.: Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells. Proceedings of the National Academy of Sciences of the United States of America 111 (44), pp. 15622 - 15629 (2014)

Kramer, K.; Sachsenberg, T.; Beckmann, B. M.; Qamar, S.; Boon, K. L.; Hentze, M. W.; Kohlbacher, O.; Urlaub, H.: Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins. Nature Methods 11 (10), pp. 1064 - 1070 (2014)

Wysoczanski, P.; Schneider, C.; Xiang, S. Q.; Munari, F.; Trowitzsch, S.; Wahl, M. C.; Lührmann, R.; Becker, S.; Zweckstetter, M.: Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 21 (10), pp. 911 - 918 (2014)

Möhlmann, S.; Mathew, R.; Neumann, P.; Schmitt, A.; Lührmann, R.; Ficner, R.: Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallographica D 70 (6), pp. 1622 - 1630 (2014)

Mozaffari-Jovin, S.; Wandersleben, T.; Santos, K. F.; Will, C. L.; Lührmann, R.; Wahl, M. C.: Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans. RNA Biology 11 (4), pp. 298 - 312 (2014)

Schmidt, C.; Groenborg, M.; Deckert, J.; Bessonov, S.; Conrad, T.; Lührmann, R.; Urlaub, H.: Mass spectrometry–based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count. RNA 20 (3), pp. 406 - 420 (2014)

Schmidt, C.; Raabe, M.; Lührmann, R.; Urlaub, H.: Analyzing the protein assembly and dynamics of the human spliceosome with SILAC. In: Stable isotope labeling by amino acids in cell culture (SILAC): Methods and protocols, pp. 227 - 244 (Ed. Warscheid, B.). Springer, New York, N.Y (2014)