Publications
Journal Article (9)
1.
Journal Article
23 (12), pp. 1770 - 1779 (2017)
Yeast Prp2 liberates the 5' splice site and the branch site adenosine for catalysis of pre-mRNA splicing. RNA 2.
Journal Article
31 (23-24), pp. 2416 - 2429 (2017)
The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex. Genes and Development 3.
Journal Article
170 (4), pp. 701 - 713, e1 - e4 (2017)
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation. Cell 4.
Journal Article
2 (7), 17062 (2017)
Structural basis for λN-dependent processive transcription antitermination. Nature Microbiology 5.
Journal Article
45 (7), pp. 4068 - 4080 (2017)
Regulation of Prp43-mediated disassembly of spliceosomes by its cofactors Ntr1 and Ntr2. Nucleic Acids Research 6.
Journal Article
6, e23533 (2017)
Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. eLife 7.
Journal Article
542 (7641), pp. 318 - 323 (2017)
Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature 8.
Journal Article
6, e21510 (2017)
Structural insights into the mechanism of the DEAH-box RNA helicase Prp43. eLife 9.
Journal Article
45 (11), pp. 6729 - 6745 (2017)
SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing. Nucleic Acids Research