Publications
Journal Article (12)
1.
Journal Article
64 (2), pp. 307 - 319 (2016)
Molecular architecture of SF3b and structural consequences of its cancer-related mutations. Molecular Cell 2.
Journal Article
353 (6306), pp. 1399 - 1405 (2016)
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 3.
Journal Article
22 (9), pp. 1329 - 1337 (2016)
ATPγS stalls splicing after B complex formation but prior to spliceosome activation. RNA 4.
Journal Article
22 (9), pp. 1427 - 1440 (2016)
A protein map of the yeast activated spliceosome as obtained by electron microscopy. RNA 5.
Journal Article
6, 31393 (2016)
U6atac snRNA stem-loop interacts with U12 p65 RNA binding protein and is functionally interchangeable with the U12 apical stem-loop III. Scientific Reports 6.
Journal Article
7, 11997 (2016)
A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity. Nature Communications 7.
Journal Article
5, e15564 (2016)
The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction. eLife 8.
Journal Article
351 (6280), pp. 1416 - 1420 (2016)
Molecular architecture of the human U4/U6.U5 tri-snRNP. Science 9.
Journal Article
13 (3), pp. 320 - 330 (2016)
Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways. RNA Biology 10.
Journal Article
22 (2), pp. 265 - 277 (2016)
Multiple protein-protein interactions converging on the Prp38 protein during activation of the human spliceosome. RNA 11.
Journal Article
72 (2), pp. 112 - 120 (2016)
Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum. Acta Crystallographica Section F 12.
Journal Article
59 (22), pp. 10190 - 10197 (2016)
Rational design of cyclic peptide inhibitors of U2AF homology motif (UHM) domains to modulate pre-mRNA splicing. Journal of Medicinal Chemistry Book (1)
13.
Book
The spliceosome and the regulation of alternative splicing. Cold Spring Harbor Lab. Pr., Cold Spring Harbor, N.Y. (accepted)