Publications
Journal Article (11)
1.
Journal Article
29 (24), pp. 2576 - 2587 (2015)
The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes and Development 2.
Journal Article
34 (24), pp. 3059 - 3073 (2015)
Protein localisation by electron microscopy reveals the architecture of the yeast spliceosomal B complex. EMBO Journal 3.
Journal Article
11 (9), e1005539 (2015)
Dynamic contacts of U2, RES, Cwc25, Prp8 and Prp45 proteins with the Pre-mRNA branch-site and 3' splice site during catalytic activation and step 1 catalysis in yeast spliceosomes. PLoS Genetics 4.
Journal Article
21 (11), pp. 1993 - 2005 (2015)
Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5‘ splice site. RNA 5.
Journal Article
125 (9), pp. 3572 - 3584 (2015)
HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models. Journal of Clinical Investigation 6.
Journal Article
162 (3), pp. 690 - 690.e1 (2015)
Snapshot: Spliceosome dynamics III. Cell 7.
Journal Article
162 (2), pp. 456 - 456.e1 (2015)
SnapShot: Spliceosome dynamics II. Cell 8.
Journal Article
4, e07320 (2015)
A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. eLife 9.
Journal Article
161 (6), pp. 1474 - 1474.e1 (2015)
SnapShot: Spliceosome dynamics I. Cell 10.
Journal Article
22 (2), pp. 138 - 144 (2015)
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology 11.
Journal Article
29 (1), pp. 94 - 107 (2015)
The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes and Development