Publications
Journal Article (13)
1.
Journal Article
40 (6), pp. 927 - 938 (2010)
3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core. Molecular Cell 2.
Journal Article
16 (12), pp. 2384 - 2403 (2010)
Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis. RNA 3.
Journal Article
18 (6), pp. 667 - 676 (2010)
An approach for de novo structure determination of dynamic molecular assemblies by electron cryomicroscopy. Structure 4.
Journal Article
30 (9), pp. 2105 - 2119 (2010)
Molecular architecture of the human Prp19/CDC5L complex. Molecular and Cellular Biology 5.
Journal Article
38 (16), pp. 5581 - 5593 (2010)
Mapping the binding site of snurportin 1 on native U1 snRNP by cross-linking and mass spectrometry. Nucleic Acids Research 6.
Journal Article
38 (2), pp. 223 - 235 (2010)
Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes. Molecular Cell 7.
Journal Article
5, e10013 (2010)
The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein. PLoS ONE 8.
Journal Article
17 (4), pp. 403 - 409 (2010)
Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis. Nature Structural and Molecular Biology 9.
Journal Article
37 (6), pp. 821 - 833 (2010)
An ancient mechanism for splicing control: U11 snRNP as an activator of alternative splicing. Molecular Cell 10.
Journal Article
17 (2), pp. 216 - 222 (2010)
Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nature Structural and Molecular Biology 11.
Journal Article
29, pp. 749 - 760 (2010)
The intronic splicing code: Multiple factors involved in ATM pseudoexon definition. The EMBO Journal 12.
Journal Article
82 (7), pp. 2784 - 2796 (2010)
Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring. Analytical Chemistry 13.
Journal Article
29, pp. 4172 - 4184 (2010)
Functional organization of the Sm core in the crystal structure of human U1 snRNP. EMBO Journal