Publications

Landthaler, M.; Yalcin, A.; Tuschl, T.: The human DiGeorge syndrome critical region gene 8 and its D-melanogaster homolog are required for miRNA biogenesis. Current Biology 14 (23), pp. 2162 - 2167 (2004)

Watkins, N. J.; Lemm, I.; Ingelfinger, D.; Schneider, C.; Hossbach, M.; Urlaub, H.; Luehrmann, R.: Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Molecular Cell 16 (5), pp. 789 - 798 (2004)

Doenmez, G.; Hartmuth, K.; Luehrmann, R.: Modified nucleotides at the 5 ' end of human U2 snRNA are required for spliceosomal E-complex formation. RNA 10 (12), pp. 1925 - 1933 (2004)

Hernandez, G.; Vazquez-Pianzola, P.; Sierra, J. M.; Rivera-Pomar, R.: Internal ribosome entry site drives cap-independent translation of reaper and heat shock protein 70 mRNAs in Drosophila embryos. RNA 10 (11), pp. 1783 - 1797 (2004)

Narayanan, U.; Achsel, T.; Luehrmann, R.; Matera, A. G.: Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein. Molecular Cell 16 (2), pp. 223 - 234 (2004)

Granneman, S.; Vogelzangs, J.; Luehrmann, R.; van Venrooij, W. J.; Pruijn, G. J. M.; Watkins, N. J.: Role of pre-rRNA base pairing and 80S complex formation in subnucleolar localization of the U3 snoRNP. Molecular and Cellular Biology 24 (19), pp. 8600 - 8610 (2004)

Medenbach, J.; Schreiner, S.; Liu, S.; Luehrmann, R.; Bindereif, A.: Human U4/U6 snRNP recycling factor p110: Mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling. Molecular and Cellular Biology 24 (17), pp. 7392 - 7401 (2004)

Strasser, A.; Dickmanns, A.; Schmidt, U.; Penka, E.; Urlaub, H.; Sekine, M.; Luehrmann, R.; Ficner, R.: Purification, crystallization and preliminary crystallographic data of the m(3)G cap-binding domain of human snRNP import factor snurportin 1. Acta Crystallographica Section D-Biological Crystallography 60, pp. 1628 - 1631 (2004)

Schaffert, N.; Hossbach, M.; Heintzmann, R.; Achsel, T.; Luehrmann, R.: RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies. EMBO Journal 23, pp. 3000 - 3009 (2004)

Ben Abdelkhalek, H.; Beckers, A.; Schuster-Gossler, K.; Pavlova, M. N.; Burkhardt, H.; Lickert, H.; Rossant, J.; Reinhardt, R.; Schalkwyk, L. C.; Mueller, I. et al.; Herrmann, B. G.; Ceolin, M.; Rivera-Pomar, R.; Gossler, A.: The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes and Development 18 (14), doi:10.1101/gad.303504, pp. 1725 - 1736 (2004)

Yuan, B. B.; Latek, R.; Hossbach, M.; Tuschl, T.; Lewitter, F.: siRNA Selection Server: an automated siRNA oligonucleotide prediction server. Nucleic Acids Research 32, pp. W-130 - W-134 (2004)

Schneider, C.; Will, C. L.; Brosius, J.; Frilander, M. J.; Luehrmann, R.: Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 101 (26), pp. 9584 - 9589 (2004)

Hernandez, G.; Vazquez-Pianzola, P.; Zurbriggen, M.; Altmann, M.; Sierra, J. M.; Rivera-Pomar, R.: Two functionally redundant isoforms of Drosophila melanogaster eukaryotic initiation factor 4B are involved in cap-dependent translation, cell survival and proliferation. European Journal of Biochemistry 271 (14), doi:10.1111/j.1432-1033.2004.04217.x, pp. 2923 - 2926 (2004)

Makarova, O.; Makarov, E. M.; Urlaub, H.; Will, C. L.; Gentzel, M.; Wilm, M.; Luehrmann, R.: A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO Journal 23 (12), pp. 2381 - 2391 (2004)

Peng, J. H.: A chemically designed enzymatic cleavage site for phosphoproteome analysis. ChemBioChem 5 (6), pp. 768 - 770 (2004)

Will, C. L.; Schneider, C.; Hossbach, M.; Urlaub, H.; Rauhut, R.; Elbashir, S. M.; Tuschl, T.; Luehrmann, R.: The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA 10 (6), pp. 929 - 941 (2004)

Boehringer, D.; Makarov, E. M.; Sander, B.; Makarova, O.; Kastner, B.; Luehrmann, R.; Stark, H.: Three-dimensional structure of a pre-catalytic human spliceosomal complex B. Nature Structural and Molecular Biology 11 (5), pp. 463 - 468 (2004)

Hartmuth, K.; Vornlocher, H. P.; Luehrmann, R.: Tobramycin affinity-tag purification of spliceosomes. In: mRNA processing and metabolism; methods and protocols, pp. 47 - 64 (Ed. Schoenberg, D. R.). Humana Pr., Totowa, N.J. (2004)