Journal Article (280)

201.
Journal Article
Hartmuth, K.; Urlaub, H.; Vornlocher, H. P.; Will, C. L.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proceedings of the National Academy of Sciences of the United States of America 99 (26), pp. 16719 - 16724 (2002)
202.
Journal Article
Granneman, S.; Pruijn, G. J. M.; Horstman, W.; van Venrooij, W. J.; Luehrmann, R.; Watkins, N. J.: The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in vitro. Journal of Biological Chemistry 277 (50), pp. 48490 - 48500 (2002)
203.
Journal Article
Makarov, E. M.; Makarova, O.; Urlaub, H.; Gentzel, M.; Will, C. L.; Wilm, M.; Luehrmann, R.: Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science 298 (5601), pp. 2205 - 2208 (2002)
204.
Journal Article
Ingelfinger, D.; Arndt-Jovin, D. J.; Luehrmann, R.; Achsel, T.: The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci. RNA-A Publication of the RNA Society 8 (12), pp. 1489 - 1501 (2002)
205.
Journal Article
Watkins, N. J.; Dickmanns, A.; Luehrmann, R.: Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP. Molecular and Cellular Biology 22 (23), pp. 8342 - 8352 (2002)
206.
Journal Article
De Antoni, A.; Schmitzova, J.; Trepte, H. H.; Gallwitz, D.; Albert, S.: Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs. Journal of Biological Chemistry 277 (43), pp. 41023 - 41031 (2002)
207.
Journal Article
Nottrott, S.; Urlaub, H.; Luehrmann, R.: Hierarchical, clustered protein interact ions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. EMBO Journal 21 (20), pp. 5527 - 5538 (2002)
208.
Journal Article
Will, C. L.; Urlaub, H.; Achsel, T.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO Journal 21 (18), pp. 4978 - 4988 (2002)
209.
Journal Article
Martinez, J.; Patkaniowska, A.; Urlaub, H.; Luehrmann, R.; Tuschl, T.: Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110 (5), pp. 563 - 574 (2002)
210.
Journal Article
Bartels, C.; Klatt, C.; Luehrmann, R.; Fabrizio, P.: The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome. EMBO Reports 3 (9), pp. 875 - 880 (2002)
211.
Journal Article
Dellaire, G.; Makarov, E. M.; Cowger, J. J. M.; Longman, D.; Sutherland, H. G. E.; Luehrmann, R.; Torchia, J.; Bickmore, W. A.: Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes. Molecular and Cellular Biology 22 (14), pp. 5141 - 5156 (2002)
212.
Journal Article
Schneider, C.; Will, C. L.; Makarova, O.; Makarov, E. M.; Luehrmann, R.: Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions. Molecular and Cellular Biology 22 (10), pp. 3219 - 3229 (2002)
213.
Journal Article
Lagos-Quintana, M.; Rauhut, R.; Yalcin, A.; Meyer, J.; Lendeckel, W.; Tuschl, T.: Identification of tissue-specific microRNAs from mouse. Current Biology 12 (9), pp. 735 - 739 (2002)
214.
Journal Article
Makarova, O.; Makarov, E. M.; Liu, S.; Vornlocher, H. P.; Luehrmann, R.: Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6 center dot U5 tri-snRNP formation and pre-mRNA splicing. EMBO Journal 21 (5), pp. 1148 - 1157 (2002)
215.
Journal Article
Huber, J.; Dickmanns, A.; Luehrmann, R.: The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro. Journal of Cell Biology 156 (3), pp. 467 - 479 (2002)
216.
Journal Article
Urlaub, H.; Hartmuth, K.; Luehrmann, R.: A two-tracked approach to analyze RNA-protein crosslinking sites in native, nonlabeled small nuclear ribonucleoprotein particles. Methods 26 (2), pp. 170 - 181 (2002)
217.
Journal Article
Mougin, A.; Gottschalk, A.; Fabrizio, P.; Luehrmann, R.; Branlant, C.: Direct probing of RNA structure and RNA-protein interactions in purifies HeLa cells and yeast spliceosomal U4/U6.U5 tri-snRNP particles. Journal of Biological Chemistry 317 (5), pp. 631 - 649 (2002)
218.
Journal Article
Meister, G.; Eggert, C.; Buehler, D.; Brahms, H.; Kambach, C.; Fischer, U.: Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln. Current Biology 11 (24), pp. 1990 - 1994 (2001)
219.
Journal Article
Achsel, T.; Stark, H.; Luehrmann, R.: The Sm domain is an ancient RNA binding motif with oligo[U] specificity. Proceedings of the National Academy of Sciences USA 98, pp. 3685 - 3689 (2001)
220.
Journal Article
Brahms, H.; Meheus, L.; De Brabandere, V.; Fischer, U.; Luehrmann, R.: Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein. RNA 7, pp. 1531 - 1542 (2001)
221.
Journal Article
Elbashir, S. M.; Harborth, J.; Lendeckel, W.; Yalcin, A.; Weber, K.; Tuschl, T.: Duplexes of 21-nucleotide RNAs mediate RNA interference in mammalian cell culture. Nature 411, pp. 494 - 498 (2001)
222.
Journal Article
Gottschalk, A.; Kastner, B.; Luehrmann, R.; Fabrizio, P.: The yeast U5 snRNP co-isolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7, pp. 1554 - 1566 (2001)
223.
Journal Article
Gottschalk, A.; Neubauer, G.; Luehrmann, R.; Fabrizio, P.: A novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly. Molecular and Cellular Biology 21, pp. 3037 - 3046 (2001)
224.
Journal Article
Kues, T.; Dickmanns, A.; Luehrmann, R.; Peters, R.; Kubitscheck, U.: High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking. Proceedings of the National Academy of Sciences USA 98, pp. 12021 - 12026 (2001)
225.
Journal Article
Lagos-Quintana, M.; Rauhut, R.; Lendeckel, W.; Tuschl, T.: Identification of novel genes coding for small expressed RNAs. Science 294, pp. 853 - 858 (2001)
226.
Journal Article
Makarova, O.; Makarov, E. M.; Luehrmann, R.: The 65-kD and 110-kD SR-related proteins of the human [U4/U6.U5] tri-snRNP are essential for association of the tri-snRNP with pre-spliceosomes. EMBO Journal 10, pp. 2553 - 2563 (2001)
227.
Journal Article
Pillai, R. S.; Will, C. L.; Luehrmann, R.; Schuemperli, D.; Mueller, B.: Purified U7 snRNPs lack the Sm proteins D 1 and D 2 but contain Lsm 10, a new 14-kDa Sm D 1-like protein. EMBO Journal 20, pp. 5470 - 5479 (2001)
228.
Journal Article
Stark, H.; Dube, P.; Luehrmann, R.; Kastner, B.: Arrangement of RNA and Proteins in the spliceosomal U1 snRNP. Nature 409, pp. 539 - 542 (2001)
229.
Journal Article
Stark, H.; Dube, P.; Luehrmann, R.; Kastner, B.: The 3-D arrangement for RNA and Proteins in the spliceosomal U1 snRNP. Nature 409, pp. 539 - 542 (2001)
230.
Journal Article
Subramaniam, V.; Jovin, T. M.; Rivera-Pomar, R.: Aromatic amino acids are critical for stability of the bicoid homeodomain. Journal of Biological Chemistry 276, DOI 10.1074/jbc.M102292200, pp. 21506 - 21511 (2001)
231.
Journal Article
Tortorici, M. A.; Albarino, C. G.; Posik, D. M.; Ghiringhelli, P. D.; Lozano, M. E.; Rivera-Pomar, R.; Romanowski, V.: Arenavirus nucleocapsid protein displays a transcriptional antitermination activity in vivo. Virus Research 73, pp. 41 - 55 (2001)
232.
Journal Article
Urlaub, H.; Raker, V. A.; Kostka, S.; Luehrmann, R.: Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. EMBO Journal 20, pp. 187 - 196 (2001)
233.
Journal Article
Vidovic, I.; Nottrott, S.; Hartmuth, K.; Luehrmann, R.; Ficner, R.: Crystal structure of the spliceosomal 15.5 kD protein bound to a U4 snRNA fragment. Molecular Cell 6, pp. 1331 - 1342 (2001)
234.
Journal Article
Will, C. L.; Luehrmann, R.: Spliceosomal U snRNP biogenesis, structure and function. Current Opinion in Cell Biology 13, pp. 290 - 301 (2001)
235.
Journal Article
Will, C. L.; Luehrmann, R.: RNP remodeling with DExH/D Boxes. Science 291, pp. 1916 - 1917 (2001)
236.
Journal Article
Will, C. L.; Schneider, C.; MacMilan, A. M.; Neubauer, G.; Wilm, M.; Luehrmann, R.; Query, C. C.: A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. EMBO Journal 20, pp. 4536 - 4546 (2001)
237.
Journal Article
Brahms, H.; Raymackers, J.; Union, A.; de Keyser, F.; Meheus, L.; Luehrmann, R.: The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D 1 and D 3 contain symmetrical dimethylarginines which form a major B-cell epitope for anti-Sm autoantibodies. Journal of Biological Chemistry 275, pp. 17122 - 17129 (2000)
238.
Journal Article
Makarov, E. M.; Makarova, O.; Achsel, T.; Luehrmann, R.: The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. Journal of Molecular Biology 298, pp. 567 - 575 (2000)
239.
Journal Article
Niessing, D.; Driever, W.; Sprenger, F.; Taubert, H.; Jaeckle, H.; Rivera-Pomar, R.: Homeodomain position 54 specifies transcriptional versus translational control by Bicoid. Molecular Cell 5, pp. 395 - 401 (2000)
240.
Journal Article
Reidt, U.; Reuter, K.; Achsel, T.; Ingelfinger, D.; Luehrmann, R.; Ficner, R.: Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin. Journal of Biological Chemistry 275, pp. 7439 - 7442 (2000)
241.
Journal Article
Urlaub, H.; Hartmuth, K.; Kostka, S.; Grelle, G.; Luehrmann, R.: A general approach for identification of RNA-protein crosslinking sites within native human spliceosomal snRNPs: Analysis of RNA-protein contacts in native U 1 and [U 4/U 6.U 5] snRNPs. Journal of Biological Chemistry 275, pp. 41458 - 41468 (2000)
242.
Journal Article
vanderVen, P. F. M.; Obermann, W.; Lemke, B.; Gautel, M.; Weber, K.; Fuerst, D. O.: Characterization of muscle filamin isoforms suggests a possible role of γ-filamin/ABP-L in sarcomeric Z-disc formation. Cell Motility and the Cytoskeleton 45, pp. 149 - 162 (2000)
243.
Journal Article
Watkins, N. J.; Segault, V.; Carpentier, B.; Nottrott, S.; Fabrizio, P.; Bachi, A.; Wilm, M.; Rosbash, M.; Branlant, C.; Luehrmann, R.: A common core RNP structure shared between the small nuclear box C/D RNPs and the spliceosomal U 4 snRNP. Cell 103, pp. 457 - 466 (2000)
244.
Journal Article
Achsel, T.; Brahms, H.; Kastner, B.; Bachi, A.; Wilm, M.; Luehrmann, R.: A doughnut-shaped heteromer of human Sm-like proteins binds to the 3′end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO Journal 18, pp. 5789 - 5802 (1999)
245.
Journal Article
Buehler, D.; Raker, V. A.; Luehrmann, R.; Fischer, U.: Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy. Human Molecular Genetics 8, pp. 2351 - 2357 (1999)
246.
Journal Article
Hartmuth, K.; Raker, V. A.; Huber, J.; Branlant, C.; Luehrmann, R.: An unusual chemical reactivity of Sm site adenosines strongly correlates with proper assembly of core U snRNP particles. Journal of Molecular Biology 285, pp. 133 - 147 (1999)
247.
Journal Article
Kambach, C.; Walke, S.; Young, R.; Avis, J. M.; Fortelle, E. D. l.; Raker, V. A.; Luehrmann, R.; Li, J.; Nagai, K.: Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell 96, pp. 375 - 387 (1999)
248.
Journal Article
Kleene, R.; Kastner, B.; Roesser, R.; Kern, H. F.: Complex formation among rat pancreatic secretory proteins under mild alkaline pH conditions. Digestion 60, pp. 305 - 313 (1999)
249.
Journal Article
Kraemer, A.; Grueter, P.; Groening, K.; Kastner, B.: Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP. Journal of Cell Biology 145, pp. 1355 - 1368 (1999)
250.
Journal Article
Niessing, D.; Dostatni, N.; Jaeckle, H.; Rivera-Pomar, R.: Sequence interval within the PEST domain of Bicoid is important for translational repression of caudal mRNA in the anterior region of the Drosophila embryo. EMBO Journal 18, pp. 1966 - 1973 (1999)
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