Theoretical and Computational Biophysics

Our research aims at an understanding of the physics and function of proteins, protein complexes, and other biomolecular structures at the atomic level. For this purpose, complex computer simulations of the atomistic dynamics are carried out. Read more about our research projects at our RESEARCH website.

Upcoming Events

Hünfeld 2023: Hybrid Workshop on Computer Simulation and Theory of Macromolecules

More information and the registration link are available on our workshop website. Join us and sign up now! Registration deadline for online-only participation is March 28, 2023. more

EBSA Congress 2023 in Stockholm, Sweden

You are welcome to join one of the largest Biophysics Congresses in Europe organized under the patronage of the European Biophysical Societies’ Association (EBSA) in close collaboration with local Swedish and other renowned international societies happening on July 31 to August 4, 2023. more

Open Positions

Student assistant wanted to support the development of our Linux cluster (22-23)

Open Postdoc Positions (11-23) in Mathematical bioPhysics

... in the research group of Aljaz Godec more

Open PhD Student Positions (12-23) in Mathematical bioPhysics

... the research group of Aljaz Godec more

Open PhD or Postdoc position for the project Theory and Algorithms for Structure Determination from Ultrafast Single Molecule XFEL Diffraction and Fluctuation Correlation X-Ray Scattering Experiments (45-22)

... in the research group of Helmut Grubmüller more

Our Research Groups

Theoretical and Computational Biophysics

Group leader: Helmut Grubmüller

Computational Biomolecular Dynamics

Group leader: Bert de Groot

Mathematical bioPhysics

Group leader: Aljaz Godec

Helmut's scientific writing guidelines

Scientific Writing: The Art of Programming Brains

Struggling with writing your paper draft or thesis? Here’s advice my students found helpful over the years. It’s version 1.0 -- Comments, suggestions, corrections highly appreciated! more

Press releases & research news

Research Group of Helmut Grubmüller

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Helmut Grubmüller elected as member of the Leopoldina

June 07, 2022

The German National Academy of Sciences Leopoldina honors the biophysicist for his outstanding scientific achievements and the special expertise in his field of research. (in German) more

Research Group of Bert de Groot

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Discovery in Parkinson’s research: Lipids influence the formation of protein clumps

November 15, 2022

In Parkinson’s patients, alpha-synuclein proteins clump together to form fibrils, which presumably damage nerve cells. A research team has now shown how lipids bind to these fibrils and influence their arrangement. They also demonstrated how the drug candidate anle138b attaches to the lipidic fibrils. The findings could open up new diagnostic and therapeutic approaches. more

Research Group of Aljaz Godec

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EU funding for novel mathematical approaches in biophysical research

February 15, 2023

Aljaz Godec. leader of the Mathematical bioPhysics research group, receives a Consolidator Grant from the European Research Council (ERC). The competition for the funding is fierce: The ERC selected only 371 of 2,222 applications in this round. more