Theoretical and Computational Biophysics

Theoretical and Computational Biophysics

Our research aims at an understanding of the physics and function of proteins, protein complexes, and other biomolecular structures at the atomic level. For this purpose, complex computer simulations of the atomistic dynamics are carried out. Read more about our research projects at our RESEARCH website.

Open Positions

Open Postdoc Position in Free Energy Calculations
... in the research group of Bert de Groot more

Our Research Groups


Helmut's scientific writing guidelines

Scientific Writing: The Art of Programming Brains
Struggling with writing your paper draft or thesis? Here’s advice my students found helpful over the years. It’s version 1.0 -- Comments, suggestions, corrections highly appreciated! more

Press releases & research news 

Research Group of Helmut Grubmüller

Helmut Grubmüller elected as member of the Leopoldina

The German National Academy of Sciences Leopoldina honors the biophysicist for his outstanding scientific achievements and the special expertise in his field of research. (in German) more

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Research Group of Bert de Groot

Discovery in Parkinson’s research: Lipids influence the formation of protein clumps

In Parkinson’s patients, alpha-synuclein proteins clump together to form fibrils, which presumably damage nerve cells. A research team has now shown how lipids bind to these fibrils and influence their arrangement. They also demonstrated how the drug candidate anle138b attaches to the lipidic fibrils. The findings could open up new diagnostic and therapeutic approaches. more

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Research Group of Aljaz Godec

Cell Adhesion Explained Through Many-Body Physics

Kristian Blom and Aljaž Godec at the MPI for Biophysical Chemistry successfully exploited the Ising model – which was originally used to describe ferromagnetism – to understand how the avidity of adhesion receptors and the strength of cellular adhesion can be regulated by mechanics. more

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