Journal Article (243)

199.
Journal Article
Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M.; Becker, S.: The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A. Journal of Biological Chemistry 282 (7), pp. 5015 - 5025 (2007)
200.
Journal Article
Kim, H. Y.; Heise, H.; Fernandez, C. O.; Baldus, M.; Zweckstetter, M.: Correlation of amyloid fibril beta-structure with the unfolded state of alpha-synuclein. ChemBioChem 8 (14), pp. 1671 - 1674 (2007)
201.
Journal Article
Korukottu, J.; Bayrhuber, M.; Montaville, P.; Jung, Y. S.; Vijayan, V.; Becker, S.; Zweckstetter, M.: Fast high-resolution protein structure determination by using unassigned NMR data. Angewandte Chemie International Edition 46 (7), pp. 1176 - 1179 (2007)
202.
Journal Article
Mukrasch, M.; Markwick, P.; Biernat, J.; von Bergen, M.; Bernado, P.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.; Blackledge, M.: Highly populated turn conformations in natively unfolded Tau protein identified from residual dipolar couplings and molecular simulation. Journal of the American Chemical Society 129 (16), pp. 5235 - 5243 (2007)
203.
Journal Article
Iwahara, J.; Zweckstetter, M.; Clore, G. M.: NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA. Proceedings of the National Academy of Sciences of the United States of America 103 (41), pp. 15062 - 15067 (2006)
204.
Journal Article
Watzlawik, J.; Skora, L.; Frense, D.; Griesinger, C.; Zweckstetter, M.; Schulz-Schaeffer, W.; Kramer, M. L.: Prion protein helix1 promotes aggregation but is not converted into beta-sheet. Journal of Biological Chemistry 281 (40), pp. 30242 - 30250 (2006)
205.
Journal Article
Ab, E.; Atkinson, A. R.; Banci, L.; Bertini, I.; Ciofi-Baffoni, S.; Brunner, K.; Diercks, T.; Dötsch, V.; Engelke, F.; Folkers, G. E. et al.; Griesinger, C.; Gronwald, W.; Günther, U.; Habeck, M.; De Jong, R. N.; Kalbitzer, H. R.; Kieffer, B.; Leeflang, B. R.; Loss, S.; Luchinat, C.; Marquardsen, T.; Moskau, D.; Neidig, K. P.; Nilges, M.; Piccioli, M.; Pierattelli, R.; Rieping, W.; Schippmann, T.; Schwalbe, H.; Travé, G.; Trenner, J.; Wöhnert, J.; Zweckstetter, M.; Kaptein, R.: NMR in the SPINE structural proteomics project. Acta Crystallographica Section D-Biological Crystallography 62 (10), pp. 1150 - 1161 (2006)
206.
Journal Article
Jauch, R.; Cho, M. K.; Jaekel, S.; Netter, C.; Schreiter, K.; Aicher, B.; Zweckstetter, M.; Jaeckle, H.; Wahl, M. C.: Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment. The EMBO Journal 25 (17), pp. 4020 - 4032 (2006)
207.
Journal Article
Binolfi, A.; Rasia, R. M.; Bertoncini, C. W.; Ceolin, M.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Interaction of alpha-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement. Journal of the American Chemical Society 128 (30), pp. 9893 - 9901 (2006)
208.
Journal Article
Bayrhuber, M.; Graf, R.; Ferber, M.; Zweckstetter, M.; Imperial, J.; Garrett, J. E.; Olivera, B. M.; Terlau, H.; Becker, S.: Production of recombinat Conkunitzin-S1 in Escherichia coli. Protein Expression and Purification 47 (2), pp. 640 - 644 (2006)
209.
Journal Article
Skora, L.; Cho, M. K.; Kim, H. Y.; Becker, S.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Charge-induced molecular alignment of intrinsically disordered proteins. Angewandte Chemie-International Edition 45 (42), pp. 7012 - 7015 (2006)
210.
Journal Article
Zweckstetter, M.: Prediction of charge-induced molecular alignment: Residual dipolar couplings at pH 3 and alignment in surfactant liquid crystalline phases. European Biophysics Journal 35 (2), pp. 170 - 180 (2006)
211.
Journal Article
Bertoncini, C. W.; Fernandez, C. O.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation. Journal of Biological Chemistry 280, pp. 30649 - 30652 (2005)
212.
Journal Article
Schnell, J. R.; Zhou, G. P.; Zweckstetter, M.; Rigby, A. C.; Chou, J. J.: Rapid and accurate structure determination of coiled-coil domains using NMR dipolar couplings: Application to cGMP-dependent protein kinase I alpha. Protein Science 14 (9), pp. 2421 - 2428 (2005)
213.
Journal Article
Zweckstetter, M.; Schnell, J. R.; Chou, J. J.: Determination of the packing mode of the coiled-coil domain of cGMP-dependent protein kinase I alpha in solution using charge-predicted dipolar couplings. Journal of the American Chemical Society 127 (34), pp. 11918 - 11919 (2005)
214.
Journal Article
Mukrasch, M.; Biernat, J.; von Bergen, M.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Sites of tau important for aggregation populate beta-structure and bind to microtubules and polyanions. Journal of Biological Chemistry 280 (26), pp. 24978 - 24986 (2005)
215.
Journal Article
Bayrhuber, M.; Vijayan, V.; Ferber, M.; Graf, R.; Korukottu, J.; Imperial, J.; Garrett, J. E.; Olivera, B. M.; Terlau, H.; Zweckstetter, M. et al.; Becker, S.: Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family - Structural and functional characterization. Journal of Biological Chemistry 280 (25), pp. 23766 - 23770 (2005)
216.
Journal Article
Vijayan, V.; Zweckstetter, M.: Simultaneous measurement of protein one-bond residual dipolar couplings without increased resonance overlap. Journal of Magnetic Resonance 174 (2), pp. 245 - 253 (2005)
217.
Journal Article
Kneuper, H.; Janausch, I. G.; Vijayan, V.; Zweckstetter, M.; Bock, V.; Griesinger, C.; Unden, G.: The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli. Journal of Biological Chemistry 280 (21), pp. 20596 - 20603 (2005)
218.
Journal Article
Rumpel, S.; Kim, H. Y.; Vijayan, V.; Becker, S.; Zweckstetter, M.: Letter to the editor: Backbone resonance assignment of the homodimeric, 35 kDa chaperone CesT from enteropathogenic Escherichia coli. Journal of Biomolecular NMR 31 (4), pp. 377 - 378 (2005)
219.
Journal Article
Rasia, R. M.; Bertoncini, C. W.; Marsh, D.; Hoyer, W.; Cherny, D. I.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Structural characterization of copper(II) binding to α-Synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 102, 10.1073/pnas.0407881102, pp. 4294 - 4299 (2005)
220.
Journal Article
Bertoncini, C. W.; Jung, Y. S.; Fernandez, C. O.; Hoyer, W.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein. Proceedings of the National Academy of Sciences of the United States of America 102 (5), pp. 1430 - 1435 (2005)
221.
Journal Article
Bernado, P.; Bertonconi, C. W.; Griesinger, C.; Zweckstetter, M.; Blackledge, M.: Defining long-range order and local disorder in native α-synuclein using residual dipolar couplings. Journal of the American Chemical Society 127 (51), pp. 17968 - 17969 (2005)
222.
Journal Article
Rumpel, S.; Razeto, A.; Pillar, C. M.; Vijayan, V.; Taylor, A.; Giller, K.; Gilmore, M. S.; Becker, S.; Zweckstetter, M.: Structure and DNA-binding properties of the cytolysin regulator CylR2 from Enterococcus faecalis. EMBO Journal 23 (18), pp. 3632 - 3642 (2004)
223.
Journal Article
Jung, Y. S.; Zweckstetter, M.: Mars - robust automatic backbone assignment of proteins. Journal of Biomolecular NMR 30 (1), pp. 11 - 23 (2004)
224.
Journal Article
Jung, Y. S.; Zweckstetter, M.: Backbone assignment of proteins with known structure using residual dipolar couplings. Journal of Biomolecular NMR 30 (1), pp. 25 - 35 (2004)
225.
Journal Article
Zweckstetter, M.; Hummer, G.; Bax, A.: Prediction of charge-induced molecular alignment of biomolecules dissolved in dilute liquid-crystalline phases. Biophysical Journal 86 (6), pp. 3444 - 3460 (2004)
226.
Journal Article
Fernandez, C. O.; Hoyer, W.; Zweckstetter, M.; Jares-Erijman, E. A.; Subramaniam, V.; Griesinger, C.; Jovin, T. M.: NMR of α-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation. EMBO Journal 23, doi:10.1038/sj.emboj.7600211, pp. 2039 - 2046 (2004)
227.
Journal Article
Razeto, A.; Giller, K.; Haas, W.; Gilmore, M. S.; Zweckstetter, M.; Becker, S.: Expression, purification, crystallization and preliminary crystallographic studies of the Enterococcus faecalis cytolysin repressor CylR2. Acta Crystallographica Section D-Biological Crystallography 60, pp. 746 - 748 (2004)
228.
Journal Article
Jung, Y. S.; Sharma, M.; Zweckstetter, M.: Simultaneous assignment and structure determination of protein backbones by using NMR dipolar couplings. Angewandte Chemie-International Edition 43 (26), pp. 3479 - 3481 (2004)
229.
Journal Article
Pappalardo, L.; Janausch, I. G.; Vijayan, V.; Zientz, E.; Junker, J.; Peti, W.; Zweckstetter, M.; Unden, G.; Griesinger, C.: The NMR structure of the sensory domain of the membranous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli. Journal of Biological Chemistry 278 (40), pp. 39185 - 39188 (2003)
230.
Journal Article
Zweckstetter, M.: Determination of molecular alignment tensors without backbone resonance assignment: Aid to rapid analysis of protein-protein interactions. Journal of Biomolecular NMR 27 (1), pp. 41 - 56 (2003)
231.
Journal Article
Verdier, L.; Sakhaii, P.; Zweckstetter, M.; Griesinger, C.: Measurement of long range H,C couplings in natural products in orienting media: a tool for structure elucidation of natural products. Journal of Magnetic Resonance 163 (2), pp. 353 - 359 (2003)
232.
Journal Article
Zweckstetter, M.; Bax, A.: Evaluation of uncertainty in alignment tensors obtained from dipolar couplings. Journal of Biomolecular NMR 23 (2), pp. 127 - 137 (2002)
233.
Journal Article
Zweckstetter, M.; Bax, A.: Characterization of molecular alignment in aqueous suspensions of Pf1 bacteriophage. Journal of Biomolecular NMR 20 (4), pp. 365 - 377 (2001)
234.
Journal Article
Stoll, R.; Renner, C.; Zweckstetter, M.; Brüggert, M.; Ambrosius, D.; Palme, S.; Engh, R. A.; Golob, M.; Breibach, I.; Buettner, R. et al.; Voelter, W.; Holak, T. A.; Bosserhoff, A. K.: The extracellular human melanoma inhibitory activity (MIA) protein adopts an SH3 domain-like fold. EMBO Journal 20 (3), pp. 340 - 349 (2001)
235.
Journal Article
Zweckstetter, M.; Bax, A.: Single-step determination of protein substructures using dipolar couplings: Aid to structural genomics. Journal of the American Chemical Society 123 (38), pp. 9490 - 9491 (2001)
236.
Journal Article
Zweckstetter, M.; Bax, A.: Prediction of sterically induced alignment in a dilute liquid crystalline phase: Aid to protein structure determination by NMR. Journal of the American ChemicaL Society 122 (15), pp. 3791 - 3792 (2000)
237.
Journal Article
Zweckstetter, M.; Holak, T. A.: Robust refocusing of 13C magnetization in multidimensional NMR experiments by adiabatic fast passage pulses. Journal of Biomolecular NMR 15 (4), pp. 331 - 334 (1999)
238.
Journal Article
Pfänder, R.; Neumann, L.; Zweckstetter, M.; Seger, C.; Holak, T. A.; Tampé, R.: Structure of the active domain of the herpes simplex virus protein ICP47 in water/sodium dodecyl sulfate solution determined by nuclear magnetic resonance spectroscopy. Biochemistry 38 (41), pp. 13692 - 13698 (1999)
239.
Journal Article
Kalus, W.; Zweckstetter, M.; Renner, C.; Sanchez, Y.; Georgescu, J.; Grol, M.; Demuth, D.; Schumacher, R.; Dony, C.; Lang, K. et al.; Holak, T. A.: Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): Implications for IGF and IGF-I receptor interactions. EMBO Journal 17 (22), pp. 6558 - 6572 (1998)
240.
Journal Article
Mühlhahn, P.; Zweckstetter, M.; Georgescu, J.; Ciosto, C.; Renner, C.; Lanzendörfer, M.; Lang, K.; Ambrosius, D.; Baier, M.; Kurth, R. et al.; Holak, T. A.: Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site. Nature Structural and Molecular Biology 5, pp. 682 - 686 (1998)
241.
Journal Article
Zweckstetter, M.; Holak, T. A.: An adiabatic multiple spin-echo pulse sequence: removal of systematic errors due to pulse imperfections and off-resonance effects. Journal of Magnetic Resonance 133 (1), pp. 134 - 147 (1998)
242.
Journal Article
Kohfeldt, E.; Göhring, W.; Mayer, U.; Zweckstetter, M.; Holak, T. A.; Chu, M. L.; Timp, R.: Conversion of the Kunitz-type module of collagen VI into a highly active trypsin inhibitor by site-directed mutagenesis. FEBS Journal 238 (2), pp. 333 - 340 (1996)
243.
Journal Article
Zweckstetter, M.; Czisch, M.; Mayer, U.; Chu, M. L.; Zinth, W.; Timpl, R.; Holak, T. A.: Structure and multiple conformations of the Kunitz-type domain from human type VI collagen alpha3(VI) chain in solution. Structure 4 (2), pp. 195 - 209 (1996)

Patent (1)

244.
Patent
Zweckstetter, M.; Karpinar, P.; Griesinger, C.: Mutant alpha-synuclein with increased toxicity. WO/2010/015714 (2010)
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