Publikationen
Zeitschriftenartikel (276)
1.
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Conformational diversity of human HP1α. Protein Science 33 (7), e5079 (2024)
2.
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Impact of distinct FG nucleoporin repeats on Nup98 self-association. Nature Communications 15, 3797 (2024)
3.
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Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions. Nature Communications 15 (1), 1925 (2024)
4.
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Regulation of tau by peptidyl-prolyl isomerases. Current Opinion in Structural Biology 84, 102739 (2024)
5.
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Multimodal interactions drive chromatin phase separation and compaction. Proceedings of the National Academy of Sciences of the United States of America 120 (50), e2308858120 (2023)
6.
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Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density. Nature Communications 14, 6839 (2023)
7.
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Role of aberrant phase separation in pathological protein aggregation. Current Opinion in Structural Biology 82, 102678 (2023)
8.
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Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology. Nature Communications 14, 5444 (2023)
9.
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Alpha-synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain. Brain Pathology 33 (5), e13196 (2023)
10.
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Parkinson's disease-linked V15A mutation facilitates α-synuclein aggregation by reducing membrane affinity. Protein Science 32 (8), e4693 (2023)
11.
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Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane. Nature Structural and Molecular Biology 30, S. 926 - 934 (2023)
12.
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Molecular-level interplay between intrinsically disordered clients and Hsp90. Current Opinion in Chemical Biology 74, 102304 (2023)
13.
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Tenth International Symposium on the Hsp90 chaperone machine. Cell Stress and Chaperones 28, S. 231 - 237 (2023)
14.
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Determining the Physico-Chemical Composition of Biomolecular Condensates from Spatially-Resolved NMR. Angewandte Chemie International Edition 62 (17), e202218078 (2023)
15.
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Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage. Nature Communications 14, 1918 (2023)
16.
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Fast Motions Dominate Dynamics of Intrinsically Disordered Tau Protein at High Temperatures. Chemistry – A European Journal 29 (17), e202203493 (2023)
17.
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Phase Separation in Biology and Disease; Current Perspectives and Open Questions. Journal of Molecular Biology 435 (5), 167971 (2023)
18.
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Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress. Science Advances 9 (5), eadd9789 (2023)
19.
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Acetylation discriminates disease-specific tau deposition. Nature Communications 14 (1), 5919 (2023)
20.
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Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II. Nature Communications 14 (1), 5979 (2023)
21.
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Structure and phase separation of the C-terminal domain of RNA polymerase II. Biological Chemistry 404 (8-9), S. 839 - 844 (2023)
22.
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Phase separation of the microtubule-associated protein tau. Essays in Biochemistry 66 (7), S. 1013 - 1021 (2022)
23.
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Polyphenols-Based Nanosheets of Propolis Modulate Cytotoxic Amyloid Fibril Assembly of α-Synuclein. ACS Chemical Neuroscience 13 (22), S. 3168 - 3179 (2022)
24.
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Metal Binding to Sodium Heparin Monitored by Quadrupolar NMR. International Journal of Molecular Sciences 23 (21), 13185 (2022)
25.
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Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98. International Journal of Molecular Sciences 23 (7), 3495 (2022)
26.
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Dynamical component exchange in a model phase separating system: an NMR-based approach. PhysChemChemPhys 24 (10), S. 6169 - 6175 (2022)
27.
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The calcium-free form of atorvastatin inhibits amyloid-β(1–42) aggregation in vitro. Journal of Biological Chemistry 298 (3), 101662 (2022)
28.
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Brain iron enrichment attenuates α-synuclein spreading after injection of preformed fibrils. Journal of Neurochemistry 159 (3), S. 554 - 573 (2021)
29.
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Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. NPJ Parkinsons Disease 7, 65 (2021)
30.
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Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils. Nature Communications 12, 4231 (2021)
31.
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Liquid–liquid phase separation of tau: From molecular biophysics to physiology and disease. Protein Science 30 (7), S. 1294 - 1314 (2021)
32.
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Low-Expressing synucleinopathy mouse models based on oligomer-forming mutations and C-terminal truncation of α-synuclein. Frontiers in Neuroscience 15, 643391 (2021)
33.
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Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis. Nature Communications 12, 3396 (2021)
34.
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Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity. Frontiers in Aging Neuroscience 13, 635760 (2021)
35.
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Special issue: Multicomponent lipid membranes—how molecular organisation leads to function. European Biophysics Journal 50 (2), S. 107 - 108 (2021)
36.
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Cooperativity of membrane-protein and protein–protein interactions control membrane remodeling by epsin 1 and affects clathrin-mediated endocytosis. Cellular and Molecular Life Sciences 78 (5), S. 2355 - 2370 (2021)
37.
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Structure, gating and interactions of the voltage-dependent anion channel. European Biophysics Journal 50 (2), S. 159 - 172 (2021)
38.
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Membrane-embedded TSPO: an NMR view. European Biophysics Journal 50 (2), S. 173 - 180 (2021)
39.
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A novel SNCA A30G mutation causes familial Parkinsonʼs disease. Movement Disorders, In Press (2021)
40.
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Structural Flexibility of Cyclosporine A Is Mediated by Amide Cis–Trans Isomerization and the Chameleonic Roles of Calcium. Journal of Physical Chemistry B 125 (5), S. 1378 - 1391 (2021)
41.
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Interplay between tau and α‐synuclein liquid–liquid phase separation. Protein Science, In Press (2021)
42.
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Disease‐associated tau phosphorylation hinders tubulin assembly within tau condensates. Angewandte Chemie International Edition 60 (2), S. 726 - 730 (2021)
43.
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Solid-state NMR investigation of the involvement of the P2 region in tau amyloid fibrils. Scientific Reports 10, 21210 (2020)
44.
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Molecular basis of the interaction of Hsp90 with its co‐chaperone Hop. Protein Science 29 (12), S. 2422 - 2432 (2020)
45.
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Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war. Nature Communications 11, 6046 (2020)
46.
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Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates. Nature Communications 11, 6041 (2020)
47.
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Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization. Scientific Reports 10, 12827 (2020)
48.
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Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 6 (30), eaba3916 (2020)
49.
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A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol. Nature Communications 11, 2729 (2020)
50.
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Determination of complex small molecule structures using molecular alignment simulation. Angewandte Chemie International Edition 59 (15), S. 6172 - 6176 (2020)