Zeitschriftenartikel (274)
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117 (6), S. 2948 - 2956 (2020)
Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proceedings of the National Academy of Sciences of the United States of America 52.
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1868 (1), 140298 (2020)
Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies. Biochimica et Biophysica Acta-Proteins and Proteomics 53.
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10, 5535 (2019)
Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts. Nature Communications 54.
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269 (8), S. 973 - 984 (2019)
Evaluation of the methoxy-X04 derivative BSC4090 for diagnosis of prodromal and early Alzheimer's disease from bioptic olfactory mucosa. European Archives of Psychiatry and Clinical Neuroscience 55.
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107, S. 3 - 5 (2019)
Towards a consensus on developmental regression. Neuroscience and Biobehavioral Reviews 56.
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138 (3), S. 415 - 441 (2019)
Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. Acta Neuropathologica 57.
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28 (9), S. 1545 - 1551 (2019)
Dynamic Aha1 co-chaperone binding to human Hsp90. Protein Science 58.
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10 (26), S. 6503 - 6507 (2019)
Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau. Chemical Science 59.
Zeitschriftenartikel
10 (1), 2909 (2019)
Lysine/RNA-interactions drive and regulate biomolecular condensation. Nature Communications 60.
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10, S. 3369 - 3375 (2019)
Reorientational dynamics of amyloid-β from NMR spin relaxation and molecular simulation. Journal of Physical Chemistry Letters 61.
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46 (6), S. 1208 - 1211 (2019)
In response to: The validity of 18F-GE180 as a TSPO imaging agent. European Journal of Nuclear Medicine and Molecular Imaging 62.
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39 (19), S. 3752 - 3769 (2019)
Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism. Journal of Neuroscience 63.
Zeitschriftenartikel
9 (3), 105 (2019)
Structure and functions of microtubule associated proteins tau and MAP2c: Similarities and differences. Biomolecules 64.
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98, S. 1 - 9 (2019)
Upregulated levels and pathological aggregation of abnormally phosphorylated Tau-Protein in children with neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews 65.
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24 (66), S. 17606 - 17611 (2018)
Insights into cholesterol/membrane protein interactions using paramagnetic solid-state NMR. Chemistry - A European Journal 66.
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57 (46), S. 15262 - 15266 (2018)
Local and global dynamics in intrinsically disordered synuclein. Angewandte Chemie International Edition 67.
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9, 4532 (2018)
Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 68.
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10 (10), S. 1383 - 1389 (2018)
Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: Binding ligands, affinity and structural features. Metallomics 69.
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25 (9), S. 833 - 840 (2018)
RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 70.
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293 (34), S. 13297 - 13309 (2018)
Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics. Journal of Biological Chemistry 71.
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285 (11), S. 1988 - 2003 (2018)
The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5. FEBS Journal 72.
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75 (12), S. 2137 - 2151 (2018)
Challenges and approaches to understand cholesterol-binding impact on membrane protein function: An NMR view. Cellular and Molecular Life Sciences 73.
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10 (19), S. 9174 - 9185 (2018)
The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. Nanoscale 74.
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25 (5), S. 384 - 393 (2018)
Mapping interactions with the chaperone network reveals factors that protect against tau aggregation. Nature Structural and Molecular Biology 75.
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57 (12), S. 3246 - 3250 (2018)
The binding mode of a repeat-like Tau sequence with tubulin. Angewandte Chemie International Edition 76.
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11, 49 (2018)
Pathophysiological consequences of neuronal alpha-Synuclein overexpression: Impacts on ion homeostasis, stress signaling, mitochondrial integrity, and electrical activity. Frontiers in Molecular Neuroscience 77.
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25 (4), S. 462 - 477 (2018)
Monitoring interactions inside cells by advanced spectroscopies: Overview of copper transporters and cisplatin. Current Medicinal Chemistry 78.
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10 (1), S. 32 - 47 (2018)
The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology. EMBO Molecular Medicine 79.
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8, 1981 (2017)
Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau. Nature Communications 80.
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21 (8), S. 2118 - 2133 (2017)
Capture of dense core vesicles at synapses by JNK-dependent phosphorylation of Synaptotagmin-4. Cell Reports 81.
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23 (53), S. 13010 - 13014 (2017)
Small molecule-induced soluble oligomers of α-synuclein with helical structure. Chemistry. A European Journal 82.
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56 (17), S. 10387 - 10395 (2017)
Bioinorganic chemistry of Parkinson's disease: Affinity and structural features of Cu(I) binding to the full-length β-synuclein protein. Inorganic Chemistry 83.
Zeitschriftenartikel
629, S. 8 - 18 (2017)
Histidine substitution in the most flexible fragments of firefly luciferase modifies its thermal stability. Archives of Biochemistry and Biophysics 84.
Zeitschriftenartikel
8, 275 (2017)
Liquid-liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau. Nature Communications 85.
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426, S. 134 - 139 (2017)
Reverse allostasis in biological systems: Minimal conditions and implications. Journal of Theoretical Biology 86.
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15 (6), e2001336 (2017)
Human cyclophilin 40 unravels neurotoxic amyloids. PLoS Biology 87.
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140 (5), S. 1399 - 1419 (2017)
Glycation potentiates alpha-synuclein-associated neurodegeneration in synucleinopathies. Brain 88.
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13 (4), e1006229 (2017)
Elucidating the structure of an infectious protein. PLoS Pathogens 89.
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24 (4), S. 407 - 413 (2017)
Mechanistic basis for the recognition of a misfolded protein by the molecular chaperone Hsp90. Nature Structural and Molecular Biology 90.
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15 (3), e2000374 (2017)
The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biology 91.
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55 (52), S. 16168 - 16171 (2016)
Structure of monomeric transthyretin carrying the clinically important T119M mutation. Angewandte Chemie International Edition 92.
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7, 13343 (2016)
BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization. Nature Communications 93.
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113 (42), S. E6506 - E6515 (2016)
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America 94.
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113 (41), S. 11465 - 11470 (2016)
Surfactant adsorption kinetics in microfluidics. Proceedings of the National Academy of Sciences of the United States of America 95.
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113 (42), S. E6506 - E6515 (2016)
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of Amerca 96.
Zeitschriftenartikel
111 (6), S. 1223 - 1234 (2016)
Voltage dependence of conformational dynamics and subconducting states of VDAC-1. Biophysical Journal 97.
Zeitschriftenartikel
291 (37), S. 19487 - 19501 (2016)
ASC pyrin domain self-associates and binds NLRP3 protein using equivalent binding interfaces. Journal of Biological Chemistry 98.
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55 (35), S. 101518 - 10521 (2016)
High-resolution NMR determination of the dynamic structure of membrane proteins. Angewandte Chemie International Edition 99.
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25 (8), S. 1563 - 1567 (2016)
The protonation state of histidine 111 regulates the aggregation of the evolutionary most conserved region of the human prion protein. Protein Science 100.
Zeitschriftenartikel
291 (31), S. 16059 - 16067 (2016)
Phosphorylation interferes with maturation of amyloid-β fibrillar structure in the N terminus. Journal of Biological Chemistry