Publikationen
Zeitschriftenartikel (294)
1.
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Using temperature coefficients to support resonance assignment of intrinsically disordered proteins. Journal of Biomolecular NMR 79, S. 59 - 65 (2025)
2.
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Interplay of p23 with FKBP51 and their chaperone complex in regulating tau aggregation. Nature Communications 16, 669 (2025)
3.
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Deep learning empowered sensor fusion boosts infant movement classification. Communications Medicine 5, 16 (2025)
4.
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Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons. Molecular Neurodegeneration 19, 100 (2024)
5.
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GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments. Proceedings of the National Academy of Sciences of the United States of America 121 (52), e2414176121 (2024)
6.
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Conformational diversity of human HP1α. Protein Science 33 (7), e5079 (2024)
7.
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Impact of distinct FG nucleoporin repeats on Nup98 self-association. Nature Communications 15, 3797 (2024)
8.
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Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions. Nature Communications 15 (1), 1925 (2024)
9.
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Regulation of tau by peptidyl-prolyl isomerases. Current Opinion in Structural Biology 84, 102739 (2024)
10.
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Multimodal interactions drive chromatin phase separation and compaction. Proceedings of the National Academy of Sciences of the United States of America 120 (50), e2308858120 (2023)
11.
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Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density. Nature Communications 14, 6839 (2023)
12.
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Role of aberrant phase separation in pathological protein aggregation. Current Opinion in Structural Biology 82, 102678 (2023)
13.
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Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology. Nature Communications 14, 5444 (2023)
14.
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Alpha-synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain. Brain Pathology 33 (5), e13196 (2023)
15.
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Parkinson's disease-linked V15A mutation facilitates α-synuclein aggregation by reducing membrane affinity. Protein Science 32 (8), e4693 (2023)
16.
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Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane. Nature Structural and Molecular Biology 30, S. 926 - 934 (2023)
17.
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Molecular-level interplay between intrinsically disordered clients and Hsp90. Current Opinion in Chemical Biology 74, 102304 (2023)
18.
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Tenth International Symposium on the Hsp90 chaperone machine. Cell Stress and Chaperones 28, S. 231 - 237 (2023)
19.
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Determining the Physico-Chemical Composition of Biomolecular Condensates from Spatially-Resolved NMR. Angewandte Chemie International Edition 62 (17), e202218078 (2023)
20.
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Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage. Nature Communications 14, 1918 (2023)
21.
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Fast Motions Dominate Dynamics of Intrinsically Disordered Tau Protein at High Temperatures. Chemistry – A European Journal 29 (17), e202203493 (2023)
22.
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Phase Separation in Biology and Disease; Current Perspectives and Open Questions. Journal of Molecular Biology 435 (5), 167971 (2023)
23.
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Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress. Science Advances 9 (5), eadd9789 (2023)
24.
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Acetylation discriminates disease-specific tau deposition. Nature Communications 14 (1), 5919 (2023)
25.
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Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II. Nature Communications 14 (1), 5979 (2023)
26.
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Structure and phase separation of the C-terminal domain of RNA polymerase II. Biological Chemistry 404 (8-9), S. 839 - 844 (2023)
27.
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Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity. Journal of Parkinson's Disease: JPD 12, S. 2397 - 2422 (2022)
28.
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Phase separation of the microtubule-associated protein tau. Essays in Biochemistry 66 (7), S. 1013 - 1021 (2022)
29.
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Molecular interactions of FG nucleoporin repeats at high resolution. Nature Chemistry 14, S. 1278 - 1285 (2022)
30.
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Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding. Molecular Cell 82 (19), S. 3693 - 3711.e10 (2022)
31.
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Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology 5 (1), 1040 (2022)
32.
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Peptidyl Prolyl Isomerase A Modulates the Liquid–Liquid Phase Separation of Proline-Rich IDPs. Journal of the American Chemical Society 144 (35), S. 16157 - 16163 (2022)
33.
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Contributions of the N-terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA-induced phase separation. Protein Science 31 (9), e4409 (2022)
34.
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Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations. Protein Science 31 (7), e4360 (2022)
35.
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A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity. Science Advances 8 (17), eabn0044 (2022)
36.
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Chicago sky blue 6B inhibits α-synuclein aggregation and propagation. Molecular Brain 15, 27 (2022)
37.
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Global Structure of the Intrinsically Disordered Protein Tau Emerges from Its Local Structure. JACS Au 2 (3), S. 673 - 686 (2022)
38.
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Conformational Dynamics of Intrinsically Disordered Proteins Regulate Biomolecular Condensate Chemistry. Chemical Reviews 122 (6), S. 6719 - 6748 (2022)
39.
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Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98. International Journal of Molecular Sciences 23 (7), 3495 (2022)
40.
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Dynamical component exchange in a model phase separating system: an NMR-based approach. PhysChemChemPhys 24 (10), S. 6169 - 6175 (2022)
41.
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The calcium-free form of atorvastatin inhibits amyloid-β(1–42) aggregation in vitro. Journal of Biological Chemistry 298 (3), 101662 (2022)
42.
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Molecular Basis of Small-Molecule Binding to α-Synuclein. Journal of the American Chemical Society 144 (6), S. 2501 - 2510 (2022)
43.
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The pathogenic R5L mutation disrupts formation of Tau complexes on the microtubule by altering local N-terminal structure. Proceedings of the National Academy of Sciences of the United States of America 119 (7), e2114215119 (2022)
44.
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A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro. Alzheimer's Research & Therapy 14, 15 (2022)
45.
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Hsp multichaperone complex buffers pathologically modified Tau. Nature Communications 13, 3668 (2022)
46.
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Brain iron enrichment attenuates α-synuclein spreading after injection of preformed fibrils. Journal of Neurochemistry 159 (3), S. 554 - 573 (2021)
47.
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Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. NPJ Parkinsons Disease 7, 65 (2021)
48.
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Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils. Nature Communications 12, 4231 (2021)
49.
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Liquid–liquid phase separation of tau: From molecular biophysics to physiology and disease. Protein Science 30 (7), S. 1294 - 1314 (2021)
50.
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Low-Expressing synucleinopathy mouse models based on oligomer-forming mutations and C-terminal truncation of α-synuclein. Frontiers in Neuroscience 15, 643391 (2021)