Journal Article (243)

100.
Journal Article
Miotto, M. C.; Valiente-Gabioud, A. A.; Rossetti, G.; Zweckstetter, M.; Carloni, P.; Selenko, P.; Griesinger, C.; Binolfi, A.; Fernández, C. O.: Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding. Journal of the American Chemical Society 137 (20), pp. 6444 - 6447 (2015)
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101.
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Fonseca-Ornelas, L.; Eisbach, S. E.; Paulat, M.; Giller, K.; Fernandez, C. O.; Outeiro, T. F.; Becker, S.; Zweckstetter, M.: Small molecule-mediated stabilization of vesicle-associated helical alpha-synuclein inhibits pathogenic misfolding and aggregation. Nature Communications 5, 5857 (2014)
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102.
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Bajaj, R.; Munari, F.; Becker, S.; Zweckstetter, M.: Interaction of the intermembrane space domain of Tim23 protein with mitochondrial membranes. Journal of Biological Chemistry 289 (50), pp. 34620 - 34626 (2014)
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103.
Journal Article
Miotto, M. C.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions. Journal of Inorganic Biochemistry 141, pp. 208 - 211 (2014)
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104.
Journal Article
Yao, X.; Becker, S.; Zweckstetter, M.: A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins. Journal of Biomolecular NMR 60 (4), pp. 231 - 240 (2014)
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105.
Journal Article
Parigi, G.; Rezaei-Ghaleh, N.; Giachetti, A.; Becker, S.; Fernandez, C.; Blackledge, M.; Griesinger, C.; Zweckstetter, M.; Luchinat, C.: Long-range correlated dynamics in intrinsically disordered proteins. Journal of the American Chemical Society 136 (46), pp. 16201 - 16209 (2014)
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106.
Journal Article
Yao, X.; Dürr, U. H. N.; Gattin, Z.; Laukat, Y.; Narayanan, R.L.; Brückner, A. K.; Meisinger, C.; Lange, A.; Becker, S.; Zweckstetter, M.: NMR-based detection of hydrogen/deuterium exchange in liposome-embedded membrane proteins. PLOS One 9 (11), e112374 (2014)
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107.
Journal Article
Bajaj, R.; Jaremko, L.; Jaremko, M.; Becker, S.; Zweckstetter, M.: Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure 22 (10), pp. 1501 - 1511 (2014)
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108.
Journal Article
Wysoczanski, P.; Schneider, C.; Xiang, S. Q.; Munari, F.; Trowitzsch, S.; Wahl, M. C.; Lührmann, R.; Becker, S.; Zweckstetter, M.: Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 21 (10), pp. 911 - 918 (2014)
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109.
Journal Article
Yin, G.; Lopes da Fonseca, T.; Eisbach, S. E.; Anduaga, A. M.; Breda, C.; Orcellet, M. L.; Szegő, E. M.; Guerreiro, P.; Lázaro, D. F.; Braus, G. H. et al.; Fernandez, C. O.; Griesinger, C.; Becker, S.; Goody, R. S.; Itzen, A.; Giorgini, F.; Outeiro, T. F.; Zweckstetter, M.: α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner. Neurobiology of Disease 70, pp. 149 - 161 (2014)
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110.
Journal Article
Jaremko, L.; Jaremko, M.; Becker, S.; Zweckstetter, M.: Toward the functional oligomerization state of tryptophan-rich sensory proteins. Protein Science 23 (8), pp. 1154 - 1160 (2014)
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111.
Journal Article
Jensen, M. R.; Zweckstetter, M.; Huang, J.; Blackledge, M.: Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy. Chemical Reviews 114 (13), pp. 6632 - 6660 (2014)
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112.
Journal Article
Xiang, S. Q.; Zweckstetter, M.: Detection of a transient intramolecular hydrogen bond using (l)J(NH) scalar couplings. Journal of Magnetic Resonance 243, pp. 93 - 97 (2014)
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113.
Journal Article
Villinger, S.; Giller, K.; Bayrhuber, M.; Lange, A.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Nucleotide interactions of the human voltage-dependent anion channel. Journal of Biological Chemistry 289 (19), pp. 13397 - 13406 (2014)
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114.
Journal Article
Miotto, M. C.; Rodriguez, E. E.; Valiente-Gabioud, A. A.; Torres-Monserrat, V.; Binolfi, A.; Quintanar, L.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific copper-catalyzed oxidation of alpha-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson's disease. Inorganic Chemistry 53 (9), pp. 4350 - 4358 (2014)
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115.
Journal Article
Munari, F.; Gajda, M. J.; Hiragami-Hamada, K.; Fischle, W.; Zweckstetter, M.: Characterization of the effects of phosphorylation by CK2 on the structure and binding properties of human HP1 beta. FEBS Letters 588 (7), pp. 1094 - 1099 (2014)
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116.
Journal Article
Rezaei-Ghaleh, N.; Amininasab, M.; Giller, K.; Kumar, S.; Stuendl, A.; Schneider, A.; Becker, S.; Walter, J.; Zweckstetter, M.: Turn plasticity distinguishes different modes of amyloid-beta aggregation. Journal of the American Chemical Society 136 (13), pp. 4913 - 4919 (2014)
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117.
Journal Article
Jaremko, L.; Jaremko, M.; Giller, K.; Becker, S.; Zweckstetter, M.: Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science 343 (6177), pp. 1363 - 1366 (2014)
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118.
Journal Article
Karagoz, G. E.; Duarte, A. M. S.; Akoury, E.; Ippel, H.; Biernat, J.; Luengo, T. M.; Radli, M.; Didenko, T.; Nordhues, B. A.; Veprintsev, D. B. et al.; Dickey, C. A.; Mandelkow, E.; Zweckstetter, M.; Boelens, R.; Madl, T.; Rudiger, S. G. D.: Hsp90-Tau complex reveals molecular basis for specificity in chaperone action. Cell 156 (5), pp. 963 - 974 (2014)
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119.
Journal Article
Schwalbe, M.; Ozenne, V.; Bibow, S.; Jaremko, M.; Jaremko, L.; Gajda, M. J.; Jensen, M. R.; Biernat, J.; Becker, S.; Mandelkow, E. et al.; Zweckstetter, M.; Blackledge, M.: Predictive atomic resolution descriptions of intrinsically disordered hTau40 and alpha-synuclein in solution from NMR and small angle scattering. Structure 22 (2), pp. 238 - 249 (2014)
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120.
Journal Article
Buhl, T.; Braun, A.; Forkel, S.; Moebius, W.; van Werven, L.; Jahn, O.; Rezaei-Ghaleh, N.; Zweckstetter, M.; Mempel, M.; Schoen, M. P. et al.; Haennssle, H. A.: Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells. Experimental Dermatology 23 (1), pp. 20 - 26 (2014)
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121.
Journal Article
Schwalbe, M.; Biernat, J.; Bibow, S.; Ozenne, V.; Jensen, M. R.; Kadavath, H.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Phosphorylation of human Tau protein by microtubule affinity-regulating kinase 2. Biochemistry 52 (50), pp. 9068 - 9079 (2013)
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122.
Journal Article
Xiang, S. Q.; Gapsys, V.; Kim, H. Y.; Bessonov, S.; Hsiao, H. H.; Möhlmann, S.; Klaukien, V.; Ficner, R.; Becker, S.; Urlaub, H. et al.; Lührmann, R.; de Groot, B.; Zweckstetter, M.: Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 21 (12), pp. 2162 - 2174 (2013)
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123.
Journal Article
Rezaei-Ghaleh, N.; Klama, F.; Munari, F.; Zweckstetter, M.: Predicting the rotational tumbling of dynamic multidomain proteins and supramolecular complexes. Angewandte Chemie International Edition 52 (43), pp. 11410 - 11414 (2013)
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124.
Journal Article
Taschenberger, G.; Toloe, J.; Tereshchenko, J.; Akerboom, J.; Wales, P.; Benz, R.; Becker, S.; Outeiro, T. F.; Looger, L. L.; Bähr, M. et al.; Zweckstetter, M.; Kügler, S.: Beta-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Annals of Neurology 74 (1), pp. 109 - 118 (2013)
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125.
Journal Article
Bouter, I.; Dittrich, K.; Wittnam, J. L.; Rezaei-Ghaleh, N.; Pillot, T.; Papot-Coutourier, S.; Lefebvre, T.; Sprenger, F.; Wirths, O.; Zweckstetter, M. et al.; Bayer, T. A.: N-truncated amyloid beta (A beta) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits. Acta Neuropathologica 126 (2), pp. 189 - 205 (2013)
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126.
Journal Article
Aggarwal, S.; Snaidero, N.; Pähler, G.; Frey, S.; Sanchez, P.; Zweckstetter, M.; Janshoff, A.; Schneider, A.; Weil, M. T.; Schaap, I. A. T. et al.; Görlich, D.; Simons, M.: Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 11 (6), e1001577 (2013)
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127.
Journal Article
Wagner, J.; Ryazanov, S.; Leonov, A.; Levin, J.; Shi, S.; Schmidt, F.; Prix, C.; Pan-Montojo, F.; Bertsch, U.; Mitteregger-Kretzschmar, G. et al.; Geissen, M.; Eiden, M.; Leidel, F.; Hirschberger, T.; Deeg, A. A.; Krauth, J.; Zinth, W.; Tavan, P.; Pilger, J.; Zweckstetter, M.; Frank, T.; Baehr, M.; Weishaupt, J. H.; Uhr, M.; Urlaub, H.; Teichmann, U.; Samwer, M.; Bötzel, K.; Groschup, M.; Kretzschmar, H.; Griesinger, C.; Giese, A.: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), pp. 795 - 813 (2013)
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128.
Journal Article
Zweckstetter, M.: Conserved amyloid core structure of stop mutants of the human prion protein. Prion 7 (3), pp. 193 - 197 (2013)
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129.
Journal Article
Munari, F.; Rezaei-Ghaleh, N.; Xiang, S. Q.; Fischle, W.; Zweckstetter, M.: Structural plasticity in human heterochromatin protein 1 beta. PLoS One 8 (4), e60887 (2013)
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130.
Journal Article
Jaremko, M.; Jaremko, L.; Kim, H. Y.; Cho, M. K.; Schwieters, C. D.; Giller, K.; Becker, S.; Zweckstetter, M.: Cold denaturation of a protein dimer monitored at atomic resolution. Nature Chemical Biology 9 (4), pp. 264 - 270 (2013)
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131.
Journal Article
Jinwal, U. K.; Akoury, E.; Abisambra, J. F.; O'Leary, J. C.; Thompson, A. D.; Blair, L. J.; Jin, Y.; Bacon, J.; Nordhues, B. A.; Cockman, M. et al.; Zhang, J.; Li, P.; Zhang, B.; Borysov, S.; Uversky, V. N.; Biernat, J.; Mandelkow, E.; Gestwicki, J. E.; Zweckstetter, M.; Dickey, C. A.: Imbalance of Hsp70 family variants fosters tau accumulation. FASEB Journal 27 (4), pp. 1450 - 1459 (2013)
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132.
Journal Article
Akoury, E.; Pickardt, M.; Gajda, M. J.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation. Angewandte Chemie-International Edition 52 (12), pp. 3511 - 3515 (2013)
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133.
Journal Article
Xiang, S. Q.; Narayanan, R. L.; Becker, S.; Zweckstetter, M.: N-H spin-spin couplings: Probing hydrogen bonds in proteins. Angewandte Chemie-International Edition 52 (12), pp. 3525 - 3528 (2013)
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134.
Journal Article
Skora, L.; Fonseca, L.; Hofele, R. V.; Riedel, D.; Giller, K.; Watzlawik, J.; Schulz-Schaeffer, W. J.; Urlaub, H.; Becker, S.; Zweckstetter, M.: Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants. Journal of Biological Chemistry 288 (5), pp. 2994 - 3002 (2013)
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135.
Journal Article
Akoury, E.; Gajda, M.; Pickhardt, M.; Biernat, J.; Pornsuwan, S.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Inhibition of tau filament formation by conformational modulation. Journal of the American Chemical Society 135 (7), pp. 2853 - 2862 (2013)
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136.
Journal Article
Skora, L.; Zweckstetter, M.: Determination of amyloid core structure using chemical shifts. Protein Science 21 (12), pp. 1948 - 1953 (2012)
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137.
Journal Article
Kroth, H.; Ansaloni, A.; Varisco, Y.; Jan, A.; Sreenivasachary, N.; Rezaei-Ghaleh, N.; Giriens, V.; Lohmann, S.; López-Deber, M. P.; Adolfsson, O. et al.; Pihlgren, M.; Paganetti, P.; Froestl, W.; Nagel-Steger, L.; Willbold, D.; Schrader, T.; Zweckstetter, M.; Pfeifer, A.; Lashuel, H. A.; Muhs, A.: Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation. Journal of Biological Chemistry 287 (41), pp. 34786 - 34800 (2012)
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138.
Journal Article
Munari, F.; Soeroes, S.; Zenn, H. M.; Schomburg, A.; Kost, N.; Schröder, S.; Klingberg, R.; Rezaei-Ghaleh, N.; Stützer, A.; Gelato, K. A. et al.; Walla, P. J.; Becker, S.; Schwarzer, D.; Zimmermann, B.; Fischle, W.; Zweckstetter, M.: Methylation of K9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome. Journal of Biological Chemistry 287 (40), pp. 33756 - 33765 (2012)
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139.
Journal Article
El-Turk, F.; Fauvet, B.; Ashrafi, A.; Ouertatani-Sakouhi, H.; Cho, M. K.; Neri, M.; Cascella, M.; Rothlisberger, U.; Pojer, F.; Zweckstetter, M. et al.; Lashuel, H.: Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: Leucine 46 hydrophobic pocket. PLoS One 7 (9), e0045024 (2012)
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140.
Journal Article
Zachariae, U.; Schneider, R.; Briones, R.; Gattin, Z.; Demers, J. P.; Giller, K.; Maier, E.; Zweckstetter, M.; Griesinger, C.; Becker, S. et al.; Benz, R.; de Groot, B. L.; Lange, A.: Beta-barrel mobility underlies closure of the voltage-dependent anion channel. Structure 20 (9), pp. 1540 - 1549 (2012)
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141.
Journal Article
Cho, M. K.; Xiang , S.; Kim, H. Y.; Becker, S.; Zweckstetter, M.: Cold-induced changes in the protein ubiquitin. PLoS One 7 (6), e37270 (2012)
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142.
Journal Article
Petroi, D.; Popova, B.; Taheri-Talesh, N.; Irniger, S.; Shapasandzadeh, H.; Zweckstetter, M.; Outeiro, T. F.; Braus, G. H.: Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome. Journal of Biological Chemistry 287 (33), pp. 27567 - 27579 (2012)
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143.
Journal Article
Rezaei-Ghaleh, N.; Blackledge, M.; Zweckstetter, M.: Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. ChemBioChem 13 (7), pp. 930 - 950 (2012)
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144.
Journal Article
Taschenberger, G.; Garrido, M.; Tereshchenko, Y.; Baehr, M.; Zweckstetter, M.; Kuegler, S.: Aggregation of alpha Synuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons. Acta Neuropathologica 123 (5), pp. 671 - 683 (2012)
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145.
Journal Article
Berger, R.; Courtieu, J.; Gil, R. R.; Griesinger, C.; Köck, M.; Lesot, P.; Luy, B.; Merlet, D.; Navarro-Vazquez, A.; Reggelin, M. et al.; Reinscheid, U. M.; Thiele, C. M.; Zweckstetter, M.: Is enantiomer assignment possible by NMR spectroscopy using residual dipolar couplings from chiral nonracemic alignment media?—A critical assessment. Angewandte Chemie International Edition 51 (33), pp. 8388 - 8391 (2012)
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146.
Journal Article
Daebel, V.; Chinnathambi, S.; Biernat, J.; Schwalbe, M.; Habenstein, B.; Loquet, A.; Akoury, E.; Tepper, K.; Mueller, H.; Baldus, M. et al.; Griesinger, C.; Zweckstetter, M.; Mandelkow, E.; Vijayan, V.; Lange, A.: β-sheet core of Tau paired helical filaments revealed by solid-state NMR. Journal of the American Chemical Society 134 (34), pp. 13982 - 13989 (2012)
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147.
Journal Article
Ozenne, V.; Schneider, R.; Yao, M.; Huang, J.-R.; Salmon, L.; Zweckstetter, M.; Jensen, M. R.; Blackledge, M.: Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. Journal of the American Chemical Society 134 (36), pp. 15138 - 15148 (2012)
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148.
Journal Article
Bibow, S.; Ozenne, V.; Biernat, J.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau. Journal of the American Chemical Society 133 (40), pp. 15842 - 15845 (2011)
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149.
Journal Article
Lamberto, C. R.; Torres-Monserrat, V.; Bertoncini, C. W.; Salvatella, X.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Toward the discovery of effective polycyclic inhibitors of alpha-Synuclein amyloid assembly. Journal of Biological Chemistry 286 (37), pp. 32036 - 32044 (2011)
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150.
Journal Article
Balija, M. B. G.; Griesinger, C.; Herzig, A.; Zweckstetter, M.; Jäckle, H.: Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila. PLoS One 6 (9), e24701 (2011)
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151.
Journal Article
Rezaei-Ghaleh, N.; Giller, K.; Becker, S.; Zweckstetter, M.: Effect of zinc binding on beta-amyloid structure and dynamics: Implications for a beta aggregation. Biophysical Journal 101 (5), pp. 1202 - 1211 (2011)
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152.
Journal Article
Luo, L.; Hannemann, M.; Koenig, S.; Hegermann, J.; Ailion, M.; Cho, M. K.; Sasidharan, N.; Zweckstetter, M.; Rensing, S. A.; Eimer, S.: The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Molecular Biology of the Cell 22 (14), pp. 2564 - 2578 (2011)
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153.
Journal Article
Krumova, P.; Meulmeester, E.; Garrido, M.; Tirard, M.; Hsiao, H. H.; Bossis, G.; Urlaub, H.; Zweckstetter, M.; Kuegler, S.; Melchior, F. et al.; Baehr, M.; Weishaupt, J. H.: Sumoylation inhibits alpha-synuclein aggregation and toxicity. Journal of Cell Biology 194 (1), pp. 49 - 60 (2011)
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154.
Journal Article
Kumar, S.; Rezaei-Ghaleh, N.; Terwel, D.; Thal, D. R.; Richard, M.; Hoch, M.; McDonald, J. M.; Wuellner, U.; Glebov, K.; Heneka, M. T. et al.; Walsh, D. M.; Zweckstetter, M.; Walter, J.: Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO Journal 30 (11), pp. 2255 - 2265 (2011)
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155.
Journal Article
Rezaei-Ghaleh, N.; Andreetto, E.; Yan, L. M.; Kapurniotu, A.; Zweckstetter, M.: Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide. PLoS One 6 (5), e20289 (2011)
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156.
Journal Article
Cho, M. K.; Kim, H. Y.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein. Protein Science 20 (2), pp. 387 - 395 (2011)
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157.
Journal Article
Binolfi, A.; Valiente-Gabioud, A. A.; Duran, R.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Exploring the structural details of Cu(I) binding to alpha-synuclein by NMR spectroscopy. Journal of the American Chemical Society 133 (2), pp. 194 - 196 (2011)
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158.
Journal Article
Bibow, S.; Mukrasch, M. D.; Chinnathambi, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The dynamic structure of filamentous tau. Angewandte Chemie-International Edition 50 (48), pp. 11520 - 11524 (2011)
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159.
Journal Article
Gruene, T.; Cho, M. K.; Karyagina, I.; Kim, H. Y.; Grosse, C.; Giller, K.; Zweckstetter, M.; Becker, S.: Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy. Journal of Biomolecular NMR 49 (2), pp. 111 - 119 (2011)
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160.
Journal Article
Villinger, S.; Briones, R.; Giller, K.; Zachariä, U.; Lange, A.; de Groot, B. L.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Functional dynamics in the voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 107 (52), pp. 22546 - 22551 (2010)
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161.
Journal Article
Binolfi, A.; Rodriguez, E. E.; Valensin, D.; D'Amelio, N.; Ippoliti, E.; Obal, G.; Duran, R.; Magistrato, A.; Pritsch, O.; Zweckstetter, M. et al.; Valensin, G.; Carloni, P.; Quintanar, L.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein. Inorganic Chemistry 49 (22), pp. 10668 - 10679 (2010)
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162.
Journal Article
de la Cruz, L.; Bajaj, R.; Becker, S.; Zweckstetter, M.: The intermembrane space domain of Tim23 is intrinsically disordered with a distinct binding region for presequences. Protein Science 19 (11), pp. 2045 - 2054 (2010)
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163.
Journal Article
Skora, L.; Becker, S.; Zweckstetter, M.: Characterization of amyloid fibrils of human beta-2-microglobulin by high-resolution magic-angle spinning NMR. ChemBioChem 11 (13), pp. 1829 - 1832 (2010)
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164.
Journal Article
Narayanan, R.L.; Dürr, U. H. N.; Bibow, S.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Automatic assignment of the intrinsically disordered protein Tau with 441-residues. Journal of the American Chemical Society 132 (34), pp. 11906 - 11907 (2010)
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165.
Journal Article
Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Cho, M. K.; Karpinar, D. P.; Le Roy, D.; Dewor, M.; Roger, T.; Bernhagen, J.; Calandra, T. et al.; Zweckstetter, M.; Lashuel, H. A.: Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. Journal of Biological Chemistry 285 (34), pp. 26581 - 26598 (2010)
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166.
Journal Article
Shoshan-Barmatz, V.; De Pinto, V.; Zweckstetter, M.; Raviv, Z.; Keinan, N.; Arbel, N.: VDAC, a multi-functional mitochondrial protein regulating cell life and death. Molecular Aspects of Medicine 31 (3), pp. 227 - 285 (2010)
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167.
Journal Article
Di Giovanni, S.; Eleuteri, S.; Paleologou, K. E.; Yin, G.; Zweckstetter, M.; Carrupt, P. A.; Lashuel, H. A.: Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect against amyloid-induced toxicity. Journal of Biological Chemistry 285 (20), pp. 14941 - 14954 (2010)
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168.
Journal Article
Paleologou, K. E.; Oueslati, A.; Shakked, G.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fernandez, C. O.; Schmid, A.; Chegini, F.; Gai, W. P. et al.; Chiappe, D.; Moniatte, M.; Schneider, B. L.; Aebischer, P.; Eliezer, D.; Zweckstetter, M.; Masliah, E.; Lashuel, H. A.: Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization and influences synuclein-membrane interactions. Journal of Neuroscience 30 (9), pp. 3184 - 3198 (2010)
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supplementary-material
169.
Journal Article
Schneider, R.; Etzkorn, M.; Giller, K.; Daebel, V.; Eisfeld, J.; Zweckstetter, M.; Griesinger, C.; Becker, S.; Lange, A.: The native conformation of the human VDAC1 N terminus. Angewandte Chemie - International Edition 49 (10), pp. 1882 - 1885 (2010)
MPG.PuRe
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170.
Journal Article
Mbefo, M. K.; Paleologou, K. E.; Boucharaba, A.; Oueslati, A.; Schell, H.; Fournier, M.; Olschewski, D.; Yin, G.; Zweckstetter, M.; Masliah, E. et al.; Kahle, P. J.; Hirling, H.; Lashuel, H. A.: Phosphorylation of synucleins by members of the polo-like kinase family. Journal of Biological Chemistry 285 (4), pp. 2807 - 2822 (2010)
MPG.PuRe
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171.
Journal Article
Salmon, L.; Nodet, G.; Oezenne, V.; Yin, G.; Jensen, M. R.; Zweckstetter, M.; Blackledge, M.: NMR characterization of long-range order in intrinsically disordered proteins. Journal of the American Chemical Society 132 (24), pp. 8407 - 8418 (2010)
MPG.PuRe
publisher-version
172.
Journal Article
Skora, L.; Becker, S.; Zweckstetter, M.: Molten globule precursor states are conformationally correlated to amyloid fibrils of human β-2-microglobulin. Journal of the American Chemical Society 132 (27), pp. 9223 - 9225 (2010)
MPG.PuRe
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173.
Journal Article
Lamberto, G. R.; Binolfi, A.; Orcelett, M. L.; Bertoncini, C. O.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proceedings of the National Academy of Sciences of the United States of America 106 (50), pp. 21057 - 21062 (2009)
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publisher-version
174.
Journal Article
Kim, H. Y.; Cho, M. K.; Kumar, A.; Maier, E.; Siebenhaar, C.; Becker, S.; Fernandez, C. O.; Lashuel, H. A.; Benz, R.; Lange, A. et al.; Zweckstetter, M.: Structural properties of pore-forming oligomers of α-synuclein. Journal of the American Chemical Society 131 (47), pp. 17482 - 17489 (2009)
MPG.PuRe
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175.
Journal Article
Fischer, D.; Mukrasch, M. D.; Biernat, J.; Bibow, S.; Blackledge, M.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Conformational changes specific for pseudophosphorylation at Ser262 selectively impair binding of tau to microtubules. Biochemistry 48 (42), pp. 10047 - 10055 (2009)
MPG.PuRe
176.
Journal Article
Jensen, M. R.; Markwick, P. R.; Meier, S.; Griesinger, C.; Zweckstetter, M.; Grzesiek, S.; Bernado, P.; Blackledge, M.: Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure 17 (9), pp. 1169 - 1185 (2009)
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177.
Journal Article
Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Roger, T.; Le Roy, D.; Karpinar, P.; Leng, L.; Bucala, R.; Zweckstetter, M.; Calandra, T. et al.; Lashuel, H. A.: A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. Biochemistry 48 (41), pp. 9858 - 9870 (2009)
MPG.PuRe
178.
Journal Article
Cho, M. K.; Nodet, G.; Kim, H. K.; Jensen, M. R.; Bernado, P.; Fernandez, C. O.; Becker, S.; Blackledge, M.; Zweckstetter, M.: Structural characterization of α-synuclein in an aggregation prone state. Protein Science 18 (9), pp. 1840 - 1846 (2009)
MPG.PuRe
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179.
Journal Article
Karpinar, P.; Gajula Balija, M. B.; Kügler, S.; Opazo, F.; Rezaei-Ghaleh, N.; Wender, N.; Kim, H. Y.; Taschenberger, G.; Falkenburger, B. H.; Heise, H. et al.; Kumar, A.; Riedel, D.; Fichtner, L.; Voigt, A.; Braus, G. H.; Giller, K.; Becker, S.; Herzig, A.; Baldus, M.; Jäckle, H.; Eimer, S.; Schulz, J. B.; Griesinger, C.; Zweckstetter, M.: Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal 28 (20), pp. 3256 - 3268 (2009)
MPG.PuRe
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180.
Journal Article
Mukrasch, M.; Bibow, S.; Korukottu, J.; Jeganathan, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biology 7 (2), e1000034 (2009)
MPG.PuRe
publisher-version
181.
Journal Article
Rezaei-Ghaleh, N.; Zweckstetter, M.; Morshedi, D.; Ebrahim-Habibi, A.; Nehmat-Gorgani, M.: Amyloidogenic potential of α-chymotrypsin in different conformational states. Biopolymers 91 (1), pp. 28 - 36 (2009)
MPG.PuRe
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182.
Journal Article
Coudevylle, N.; Montaville, P.; Leonov, M.; Zweckstetter, M.; Becker, S.: Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A. Journal of Biological Chemistry 283 (51), pp. 35918 - 35928 (2008)
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183.
Journal Article
Rumpel, S.; Lakshmi, R.; Becker, S.; Zweckstetter, M.: Assignment-free solution NMR method reveals CesT as an unswapped homodimer. Protein Science 17 (11), pp. 2015 - 2019 (2008)
MPG.PuRe
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184.
Journal Article
Soragni, A.; Zambelli, B.; Mukrasch, M.; Biernat, J.; Jeganathan, S.; Griesinger, C.; Ciurli, S.; Mandelkow, E.; Zweckstetter, M.: Structural characterization of binding of Cu(II) to Tau protein. Biochemistry 47 (41), pp. 10841 - 10851 (2008)
MPG.PuRe
185.
Journal Article
Bayrhuber, M.; Meins, T.; Habeck, M.; Becker, S.; Giller, K.; Villinger, S.; Vonrhein, C.; Griesinger, C.; Zweckstetter, M.; Zeth, K.: Structure of the human voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 105 (40), pp. 15370 - 15375 (2008)
MPG.PuRe
publisher-version
186.
Journal Article
El-Turk, F.; Cascella, M.; Ouertatami-Sakonhi, H.; Lakshmi, R. N.; Leng, L.; Bucala, R.; Zweckstetter, M.; Rothlisberger, U.; Lashuel, H. A.: The conformational flexibility of the carboxy terminal residues 105−114 Is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry 47 (40), pp. 10740 - 10756 (2008)
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187.
Journal Article
Binolfi, A.; Lamberto, G. R.; Duran, R.; Quintanar, L.; Bertoncini, C. W.; Souza, J. M.; Cervenansky, C.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), pp. 11801 - 11812 (2008)
MPG.PuRe
188.
Journal Article
Kim, H. Y.; Cho, M. K.; Riedel, D.; Fernandez, C. O.; Zweckstetter, M.: Dissociation of amyloid fibrils of α-synuclein in supercooled water. Angewandte Chemie International Edition 47 (27), pp. 5046 - 5048 (2008)
MPG.PuRe
189.
Journal Article
Korukottu, J.; Schneider, R.; Vijayan, V.; Lange, A.; Pongs, O.; Becker, S.; Baldus, M.; Zweckstetter, M.: High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy. PLoS One 3 (6), e2359 (2008)
MPG.PuRe
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190.
Journal Article
Paleologou, K. E.; Schmid, A. W.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fredenburg, R. A.; Lansbury, P. T.; Fernandez, C. O.; Eliezer, D.; Zweckstetter, M. et al.; Lashuel, H. A.: Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein. The Journal of Biological Chemistry 283, pp. 16895 - 16905 (2008)
MPG.PuRe
publisher-version
191.
Journal Article
Sevvana, M.; Vijayan, V.; Zweckstetter, M.; Reinelt, S.; Madden, D. R.; Herbst-Irmer, R.; Sheldrick, G. M.; Bott, M.; Griesinger, C.; Becker, S.: A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. Journal of Molecular Biology 377 (2), pp. 512 - 523 (2008)
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192.
Journal Article
Zweckstetter, M.: NMR: prediction of molecular alignment from structure using the PALES software. Nature Protocols 3 (4), pp. 679 - 690 (2008)
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193.
Journal Article
Montaville, P.; Condevylle, N.; Radhakrishnan, A.; Leonov, A.; Zweckstetter, M.; Becker, S.: The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), pp. 1025 - 1034 (2008)
MPG.PuRe
publisher-version
194.
Journal Article
Rumpel, S.; Becker, S.; Zweckstetter, M.: High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment. Journal of Biomolecular NMR 40 (1), pp. 1 - 13 (2008)
MPG.PuRe
publisher-version
195.
Journal Article
Bertoncini, C. W.; Rasia, R. M.; Lamberto, G. R.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. Journal of Molecular Biology 372 (3), pp. 708 - 722 (2007)
MPG.PuRe
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196.
Journal Article
Mukrasch, M.; von Bergen, M.; Biernat, J.; Fischer, D.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The "jaws" of the tau-microtubule interaction. Journal of Biological Chemistry 282 (16), pp. 12230 - 12239 (2007)
MPG.PuRe
publisher-version
197.
Journal Article
Cho, M. K.; Kim, H. Y.; Bernado, P.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. Journal of the American Chemical Society 129 (11), pp. 3032 - 3033 (2007)
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198.
Journal Article
Fischer, D.; Mukrasch, M.; von Bergen, M.; Klos-Witkowska, A.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural and microtubule binding properties of tau mutants of frontotemporal dementias. Biochemistry 46 (10), pp. 2574 - 2582 (2007)
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