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540 (7634), pp. 607 - 610 (2016)
Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature 152.
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113 (45), pp. 12733 - 12738 (2016)
Nucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 153.
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Inference of gene regulation functions from dynamic transcriptome data. eLife 154.
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FBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 155.
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44 (4), pp. 1177 - 1182 (2016)
Structure determination of transient transcription complexes. Biochemical Society Transactions 156.
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RNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 157.
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Mediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 158.
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Architecture and RNA binding of the human negative elongation factor. eLife 159.
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352 (6290), pp. 1225 - 1228 (2016)
TT-seq maps the human transient transcriptome. Science 160.
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533 (7603), pp. 353 - 358 (2016)
Transcription initiation complex structures elucidate DNA opening. Nature 161.
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113 (11), pp. 2946 - 2951 (2016)
Mechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 162.
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36 (5), pp. 820 - 831 (2016)
Structure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 163.
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12 (2), 857 (2016)
Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 164.
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Structure of transcribing mammalian RNA polymerase II. Nature 165.
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61 (2), pp. 305 - 314 (2016)
Heptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 166.
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83 (10), pp. 1849 - 1858 (2015)
Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 167.
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71 (9), pp. 1850 - 1855 (2015)
An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 168.
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58 (6), pp. 1079 - 1089 (2015)
Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 169.
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43 (7), pp. 3726 - 3735 (2015)
A model for transcription initiation in human mitochondria. Nucleic Acids Research 170.
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16 (3), pp. 129 - 143 (2015)
Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 171.
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Architecture of the RNA polymerase II–Mediator core initiation complex. Nature 172.
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25 (2), pp. 155 - 166 (2015)
BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 173.
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Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 174.
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159 (5), pp. 985 - 994 (2014)
A tale of chromatin and transcription in 100 structures. Cell 175.
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55 (5), pp. 745 - 757 (2014)
Transcriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 176.
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55 (3), pp. 467 - 481 (2014)
Molecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 177.
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Conserved architecture of the core RNA polymerase II initiation complex. Nature Communications 178.
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9 (6), e100736 (2014)
Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions. PLoS One 179.
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289 (25), pp. 17446 - 17452 (2014)
Rpb4 functions mainly in mRNA synthesis by RNA polymerase II. Journal of Biological Chemistry 180.
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42 (6), pp. 4043 - 4055 (2014)
Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Research 181.
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42 (6), pp. 3884 - 3893 (2014)
A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Research 182.
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21 (2), pp. 175 - 179 (2014)
RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7. Nature Structural and Molecular Biology 183.
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10 (1), 717 (2014)
Periodic mRNA synthesis and degradation co-operate during cell cycle gene expression. Molecular Systems Biology 184.
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9 (11), e1003914 (2013)
Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II. PLoS Genetics 185.
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155 (5), pp. 1075 - 1087 (2013)
Transcriptome surveillance by selective termination of noncoding RNA synthesis. Cell 186.
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288 (51), pp. 36676 - 36690 (2013)
The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. Journal of Biological Chemistry 187.
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502 (7473), pp. 650 - 655 (2013)
RNA polymerase I structure and transcription regulation. Nature 188.
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52 (1), pp. 52 - 62 (2013)
Global analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levels. Molecular cell 189.
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20 (11), pp. 1298 - 1303 (2013)
Structure of human mitochondrial RNA polymerase elongation complex. Nature Structural and Molecular Biology 190.
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110 (38), pp. 15277 - 15282 (2013)
Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proceedings of the National Academy of Sciences of the USA 191.
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41 (20), pp. 9266 - 9273 (2013)
Model of the Mediator middle module based on protein cross-linking. Nucleic Acids Research 192.
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33 (19), pp. 3805 - 3816 (2013)
Cap completion and C-terminal repeat domain kinase recruitment underlie the initiation-elongation transition of RNA polymerase II. Molecular and cellular biology 193.
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41 (14), pp. 7048 - 7059 (2013)
The RNA polymerase trigger loop functions in all three phases of the transcription cycle. Nucleic acids research 194.
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153 (5), pp. 943 - 944 (2013)
Transitions for regulating early transcription. Cell 195.
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10 (6), pp. 1042 - 1056 (2013)
Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan. RNA Biology 196.
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32 (6), pp. 771 - 772 (2013)
Struggling to let go: A non‐coding RNA directs its own extension and destruction. EMBO Journal 197.
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Structure and function of the initially transcribing RNA polymerase II–TFIIB complex. Nature 198.
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1829 (1), pp. 9 - 19 (2013)
Structural basis of transcription elongation. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 199.
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Structure of the Mediator head module. Nature 200.
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Mediator phosphorylation prevents stress response transcription during non-stress conditions. Journal of Biological Chemistry