Publikationen

1.

Zeitschriftenartikel

Chen, Y.; Kokic, G.; Dienemann, C.; Dybkov, O.; Urlaub, H.; Cramer, P.: Structure of the transcribing RNA polymerase II–Elongin complex. Nature Structural & Molecular Biology (2023)

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2.

Zeitschriftenartikel

Palau, A.; Segerberg, F.; Lidschreiber, M.; Lidschreiber, K.; Naughton, A.J.; Needhamsen, M.; Jung, L.A.; Jagodic, M.; Cramer, P.; Lehmann, S. et al.; Carlsten, M.; Lennartsson, A.: Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells. Leukemia 37, S. 1830 - 1841 (2023)

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3.

Zeitschriftenartikel

Garg, G.; Dienemann, C.; Farnung, L.; Schwarz, J.; Linden, A.; Urlaub, H.; Cramer, P.: Structural insights into human co-transcriptional capping. Molecular Cell 83 (14), S. 2464 - 2477.e5 (2023)

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4.

Zeitschriftenartikel

Rouvière, J. O.; Salerno-Kochan, A.; Lykke-Andersen, S.; Garland, W.; Dou, Y.; Rathore, O.; Molska, E. Š.; Wu, G.; Schmid, M.; Bugai, A. et al.; Jakobsen, L.; Zumer, K.; Cramer, P.; Andersen, J. S.; Conti, E.; Jensen, T. H.: ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts. Molecular Cell 83 (13), S. 2240 - 2257 (2023)

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5.

Zeitschriftenartikel

Ramasamy, S.; Aljahani, A.; Karpinska, M. A.; Cao, N. T. B.; Velychko, T.; Cruz, J. N.; Lidschreiber, M.; Oudelaar, A. M.: The Mediator complex regulates enhancer-promoter interactions. Nature Structural and Molecular Biology 30, S. 991 - 1000 (2023)

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6.

Zeitschriftenartikel

Abril-Garrido, J.; Dienemann, C.; Grabbe, F.; Velychko, T.; Lidschreiber, M.; Wang, H.; Cramer, P.: Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Molecular Cell 83 (11), S. 1798 - 1809.e7 (2023)

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7.

Zeitschriftenartikel

Schmitzová, J.; Cretu, C.; Dienemann, C.; Urlaub, H.; Pena, V.: Structural basis of catalytic activation in human splicing. Nature 617, S. 842 - 850 (2023)

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8.

Zeitschriftenartikel

Rengachari, S.; Schilbach, S.; Cramer, P.: Mediator structure and function in transcription initiation. Biological Chemistry, aop (2023)

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9.

Zeitschriftenartikel

Schilbach, S.; Wang, H.; Dienemann, C.; Cramer, P.: Yeast PIC-mediator structure with RNA polymerase II C-terminal domain. Proceedings of the National Academy of Sciences of the United States of America 120 (15), e2220542120 (2023)

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10.

Zeitschriftenartikel

Dybkov, O.; Preußner, M.; El Ayoubi, L.; Feng, V.-Y.; Harnisch, C.; Merz, K.; Leupold, P.; Yudichev, P.; Agafonov, D. E.; Will, C. L. et al.; Girard, C.; Dienemann, C.; Urlaub, H.; Kastner, B.; Heyd, F.; Lührmann, R.: Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins. Science Advances 9 (9), eadf178 (2023)

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11.

Zeitschriftenartikel

Wang, H.; Schilbach, S.; Ninov, M.; Urlaub, H.; Cramer, P.: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nature Structural and Molecular Biology 30, S. 226 - 232 (2023)

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12.

Zeitschriftenartikel

Dienemann, C.: Towards automating single-particle cryo-EM data acquisition. IUCRJ 10 (Part 1), S. 4 - 5 (2023)

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13.

Zeitschriftenartikel

Rengachari, S.; Schilbach, S.; Kaliyappan, T.; Gouge, J.; Zumer, K.; Schwarz, J.; Urlaub, H.; Dienemann, C.; Vannini, A.; Cramer, P.: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nature Structural and Molecular Biology 29, S. 1159 - 1169 (2022)

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14.

Zeitschriftenartikel

Frieg, B.; Antonschmidt, L.; Dienemann, C.; Geraets, J. A.; Najbauer, E. E.; Matthes, D.; de Groot, B. L.; Andreas, L. B.; Becker, S.; Griesinger, C. et al.; Schröder, G. F.: The 3D structure of lipidic fibrils of α-synuclein. Nature Communications 13 (1), 6810 (2022)

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15.

Zeitschriftenartikel

Yahya, G.; Menges, P.; Amponsah, P. S.; Ngandiri, D. A.; Schulz, D.; Wallek, A. U.; Kulak, N. A.; Mann, M.; Cramer, P.; Savage, V. et al.; Raeschle, M.; Storchova, Z.: Sublinear scaling of the cellular proteome with ploidy. Nature Communications 13 (1), 6182 (2022)

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16.

Zeitschriftenartikel

Xue, L.; Lenz, S.; Zimmermann-Kogadeeva, M.; Tegunov, D.; Cramer, P.; Bork, P.; Rappsilber, J.; Mahamid, J.: Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature 610 (7930), S. 205 - 211 (2022)

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17.

Zeitschriftenartikel

Obeng, E. M.; Fianu, I.; Danquah, M. K.: Multivalent ACE2 engineering-A promising pathway for advanced coronavirus nanomedicine development. Nano Today 46, 101580 (2022)

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18.

Zeitschriftenartikel

Frieg, B.; Geraets, J. A.; Strohaeker, T.; Dienemann, C.; Mavroeidi, P.; Jung, B. C.; Kim, W. S.; Lee, S.-J.; Xilouri, M.; Zweckstetter, M. et al.; Schroeder, G. F.: Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology 5 (1), 1040 (2022)

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19.

Zeitschriftenartikel

de Opakua, A. I.; Geraets, J. A.; Frieg, B.; Dienemann, C.; Savastano, A.; Rankovic, M.; Cima-Omori, M.-S.; Schröder, G. F.; Zweckstetter, M.: Molecular interactions of FG nucleoporin repeats at high resolution. Nature Chemistry 14, S. 1278 - 1285 (2022)

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20.

Zeitschriftenartikel

Antonschmidt, L.; Matthes, D.; Dervişoğlu, R.; Frieg, B.; Dienemann, C.; Leonov, A.; Nimerovsky, E.; Sant, V.; Ryazanov, S.; Giese, A. et al.; Schröder, G.; Becker, S.; de Groot, B. L.; Griesinger, C.; Andreas, L. B.: The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils. Nature Communications 13, S. 5385 - 5394 (2022)

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21.

Zeitschriftenartikel

Farnung, L.; Ochmann, M.; Garg, G.; Vos, S.; Cramer, P.: Structure of a backtracked hexasomal intermediate of nucleosome transcription. Molecular Cell 82 (17), S. 3126 - 3134.e7 (2022)

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22.

Zeitschriftenartikel

Fietze, T.; Wilk, P.; Kabinger, F.; Anoosheh, S.; Hofer, A.; Lundin, D.; Feiler, C. G.; Weiss, M. S.; Loderer, C.: HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry 61 (15), S. 1633 - 1641 (2022)

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23.

Zeitschriftenartikel

Xiong, L.; Tolen, E. A.; Choi, J.; Velychko, S.; Caizzi, L.; Velychko, T.; Adachi, K.; MacCarthy, C. M.; Lidschreiber, M.; Cramer, P. et al.; Schöler, H. R.: Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. eLife 11, e71533 (2022)

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24.

Zeitschriftenartikel

Dombrowski, M.; Engeholm, M.; Dienemann, C.; Dodonova, S. O.; Cramer, P.: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nature Structural and Molecular Biology 29 (5), S. 493 - 501 (2022)

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25.

Zeitschriftenartikel

Sahu, B.; Hartonen, T.; Pihlajamaa, P.; Wei, B.; Dave, K.; Zhu, F.; Kaasinen, E.; Lidschreiber, K.; Lidschreiber, M.; Daub, C. O. et al.; Cramer, P.; Kivioja, T.; Taipale, J.: Sequence determinants of human gene regulatory elements. Nature Genetics 54 (3), S. 283 - 294 (2022)

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26.

Zeitschriftenartikel

Downes, D. J.; Smith, A. L.; Karpinska, M. A.; Velychko, T.; Rue-Albrecht, K.; Sims, D.; Milne, T. A.; Davies, J. O. J.; Oudelaar, A. M.; Hughes, J. R.: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture. Nature Protocols 17 (2), S. 445 - 475 (2022)

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27.

Zeitschriftenartikel

Baar, T.; Dümcke, S.; Gressel, S.; Schwalb, B.; Dilthey, A.; Cramer, P.; Tresch, A.: RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. G3: Genes, Genomes, Genetics 12 (5), jkac054 (2022)

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28.

Zeitschriftenartikel

Shao, R.; Kumar, B.; Lidschreiber, K.; Lidschreiber, M.; Cramer, P.; Elsässer, S. J.: Distinct transcription kinetics of pluripotent cell states. Molecular Systems Biology 18 (1), e10407 (2022)

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29.

Zeitschriftenartikel

Fianu, I.; Chen, Y.; Dienemann, C.; Dybkov, O.; Linden, A.; Urlaub, H.; Cramer, P.: Structural basis of Integrator-mediated transcription regulation. Science 374 (6569), S. 883 - 887 (2021)

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30.

Zeitschriftenartikel

Kokic, G.; Wagner, F. R.; Chernev, A.; Urlaub, H.; Cramer, P.: Structural basis of human transcription–DNA repair coupling. Nature 598 (7880), S. 368 - 372 (2021)

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31.

Zeitschriftenartikel

Aibara, S.; Dienemann, C.; Cramer, P.: Structure of an inactive RNA polymerase II dimer. Nucleic Acids Research 49 (18), S. 10747 - 10755 (2021)

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32.

Zeitschriftenartikel

García-Martínez, J.; Medina, D. A.; Bellvís, P.; Sun, M.; Cramer, P.; Chávez, S.; Pérez-Ortín, J. E.: The total mRNA concentration buffering system in yeast is global rather than gene-specific. RNA 27 (10), S. 1281 - 1290 (2021)

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33.

Zeitschriftenartikel

Güttler, T.; Aksu, M.; Dickmanns, A.; Stegmann, K. M.; Gregor, K.; Rees, R.; Taxer, W.; Rymarenko, O.; Schünemann, J.; Dienemann, C. et al.; Gunkel, P.; Mussil, B.; Krull, J.; Teichmann, U.; Groß, U.; Cordes, V.; Dobbelstein, M.; Görlich, D.: Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 40 (19), e107985 (2021)

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34.

Zeitschriftenartikel

Bhatta, A.; Dienemann, C.; Cramer, P.; Hillen, H.: Structural basis of RNA processing by human mitochondrial RNase P. Nature Structural and Molecular Biology 28 (9), S. 713 - 723 (2021)

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35.

Zeitschriftenartikel

Cramer, P.: AlphaFold2 and the future of structural biology. Nature Structural and Molecular Biology 28 (9), S. 704 - 705 (2021)

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36.

Zeitschriftenartikel

Kabinger, F.; Stiller, C.; Schmitzova, J.; Dienemann, C.; Kokic, G.; Hillen, H. S.; Höbartner, C.; Cramer, P.: Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nature Structural and Molecular Biology 28 (9), S. 740 - 746 (2021)

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37.

Zeitschriftenartikel

Jochheim, F. A.; Tegunov, D.; Hillen, H. S.; Schmitzova, J.; Kokic, G.; Dienemann, C.; Cramer, P.: The structure of a dimeric form of SARS-CoV-2 polymerase. Communications Biology 4, 999 (2021)

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38.

Zeitschriftenartikel

Zumer, K.; Maier, K. C.; Farnung, L.; Jaeger, M. G.; Rus, P.; Winter, G.; Cramer, P.: Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo. Molecular Cell 81 (15), S. 3096 - 3109.e8 (2021)

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39.

Zeitschriftenartikel

Wang, H.; Xiong, L.; Cramer, P.: Structures and implications of TBP–nucleosome complexes. Proceedings of the National Academy of Sciences of the USA 118 (30), e2108859118 (2021)

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40.

Zeitschriftenartikel

Schilbach, S.; Aibara, S.; Dienemann, C.; Grabbe, F.; Cramer, P.: Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening. Cell 184 (15), S. 4064 - 4072.e28 (2021)

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41.

Zeitschriftenartikel

Chen, Y.; Vos, S. M.; Dienemann, C.; Ninov, M.; Urlaub, H.; Cramer, P.: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 81 (16), S. 3386 - 3399.e10 (2021)

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42.

Zeitschriftenartikel

Aibara, S.; Schilbach, S.; Cramer, P.: Structures of mammalian RNA polymerase II pre-initiation complexes. Nature 594 (7861), S. 124 - 128 (2021)

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supplementary-material

43.

Zeitschriftenartikel

Rengachari, S.; Schilbach, S.; Aibara, S.; Dienemann, C.; Cramer, P.: Structure of the human Mediator-RNA polymerase II pre-initiation complex. Nature 594 (7861), S. 129 - 133 (2021)

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supplementary-material

44.

Zeitschriftenartikel

Osman, S.; Mohammad, E.; Lidschreiber, M.; Stuetzer, A.; Bazsó, F. L.; Maier, K. C.; Urlaub, H.; Cramer, P.: The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 296, 100734 (2021)

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45.

Zeitschriftenartikel

Oberbeckmann, E.; Niebauer, V.; Watanabe, S.; Farnung, L.; Moldt, M.; Schmid, A.; Cramer, P.; Peterson, C. L.; Eustermann, S.; Hopfner, K.-P. et al.; Korber, P.: Ruler elements in chromatin remodelers set nucleosome array spacing and phasing. Nature Communications 12, 3232 (2021)

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46.

Zeitschriftenartikel

Fianu, I.; Dienemann, C.; Aibara, S.; Schilbach, S.; Cramer, P.: Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2. Communications Biology 4, 606 (2021)

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47.

Zeitschriftenartikel

Caizzi, L.; Monteiro-Martins, S.; Schwalb, B.; Lysakovskaya, K.; Schmitzova, J.; Sawicka, A.; Chen, Y.; Lidschreiber, M.; Cramer, P.: Efficient RNA polymerase II pause release requires U2 snRNP function. Molecular Cell 81 (9), S. 1920 - 1934.e9 (2021)

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48.

Zeitschriftenartikel

Hillen, H. S.; Markov, D. A.; Wojtas, I. D.; Hofmann, K. B.; Lidschreiber, M.; Cowan, A. T.; Jones, J. L.; Temiakov, D.; Cramer, P.; Anikin, M.: The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs. Proceedings of the National Academy of Sciences of the USA 118 (15), e2009329118 (2021)

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49.

Zeitschriftenartikel

Farnung, L.; Ochmann, M.; Engeholm, M.; Cramer, P.: Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nature Structural and Molecular Biology 28 (4), S. 382 - 387 (2021)

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50.

Zeitschriftenartikel

Choi, J.; Lysakovskaia, K.; Stik, G.; Demel, C.; Söding, J.; Tian, T. V.; Graf, T.; Cramer, P.: Evidence for additive and synergistic action of mammalian enhancers during cell fate determination. eLife 10, e65381 (2021)

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Publikationen

Zeitschriftenartikel (299)