Publikationen
Zeitschriftenartikel (283)
1.
Zeitschriftenartikel
610 (7930), S. 205 - 211 (2022)
Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature 2.
Zeitschriftenartikel
46, 101580 (2022)
Multivalent ACE2 engineering-A promising pathway for advanced coronavirus nanomedicine development. Nano Today 3.
Zeitschriftenartikel
5 (1), 1040 (2022)
Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology 4.
Zeitschriftenartikel
14, S. 1278 - 1285 (2022)
Molecular interactions of FG nucleoporin repeats at high resolution. Nature Chemistry 5.
Zeitschriftenartikel
13, S. 5385 - 5394 (2022)
The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils. Nature Communications 6.
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82 (17), S. 3126 - 3134.e7 (2022)
Structure of a backtracked hexasomal intermediate of nucleosome transcription. Molecular Cell 7.
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61 (15), S. 1633 - 1641 (2022)
HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry 8.
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11, e71533 (2022)
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. eLife 9.
Zeitschriftenartikel
29 (5), S. 493 - 501 (2022)
Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nature Structural and Molecular Biology 10.
Zeitschriftenartikel
54 (3), S. 283 - 294 (2022)
Sequence determinants of human gene regulatory elements. Nature Genetics 11.
Zeitschriftenartikel
17 (2), S. 445 - 475 (2022)
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture. Nature Protocols 12.
Zeitschriftenartikel
18, e10407 (2022)
Distinct transcription kinetics of pluripotent cell states. Molecular Systems Biology 13.
Zeitschriftenartikel
12 (5), jkac054 (2022)
RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. G3: Genes, Genomes, Genetics 14.
Zeitschriftenartikel
374 (6569), S. 883 - 887 (2021)
Structural basis of Integrator-mediated transcription regulation. Science 15.
Zeitschriftenartikel
598 (7880), S. 368 - 372 (2021)
Structural basis of human transcription–DNA repair coupling. Nature 16.
Zeitschriftenartikel
49 (18), S. 10747 - 10755 (2021)
Structure of an inactive RNA polymerase II dimer. Nucleic Acids Research 17.
Zeitschriftenartikel
27 (10), S. 1281 - 1290 (2021)
The total mRNA concentration buffering system in yeast is global rather than gene-specific. RNA 18.
Zeitschriftenartikel
40 (19), e107985 (2021)
Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 19.
Zeitschriftenartikel
28 (9), S. 713 - 723 (2021)
Structural basis of RNA processing by human mitochondrial RNase P. Nature Structural and Molecular Biology 20.
Zeitschriftenartikel
28 (9), S. 704 - 705 (2021)
AlphaFold2 and the future of structural biology. Nature Structural and Molecular Biology 21.
Zeitschriftenartikel
28 (9), S. 740 - 746 (2021)
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nature Structural and Molecular Biology 22.
Zeitschriftenartikel
4, 999 (2021)
The structure of a dimeric form of SARS-CoV-2 polymerase. Communications Biology 23.
Zeitschriftenartikel
81 (15), S. 3096 - 3109.e8 (2021)
Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo. Molecular Cell 24.
Zeitschriftenartikel
118 (30), e2108859118 (2021)
Structures and implications of TBP–nucleosome complexes. Proceedings of the National Academy of Sciences of the USA 25.
Zeitschriftenartikel
184 (15), S. 4064 - 4072.e28 (2021)
Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening. Cell 26.
Zeitschriftenartikel
81 (16), S. 3386 - 3399.e10 (2021)
Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 27.
Zeitschriftenartikel
594 (7861), S. 124 - 128 (2021)
Structures of mammalian RNA polymerase II pre-initiation complexes. Nature 28.
Zeitschriftenartikel
594 (7861), S. 129 - 133 (2021)
Structure of the human Mediator-RNA polymerase II pre-initiation complex. Nature 29.
Zeitschriftenartikel
296, 100734 (2021)
The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 30.
Zeitschriftenartikel
12, 3232 (2021)
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing. Nature Communications 31.
Zeitschriftenartikel
4, 606 (2021)
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2. Communications Biology 32.
Zeitschriftenartikel
81 (9), S. 1920 - 1934.e9 (2021)
Efficient RNA polymerase II pause release requires U2 snRNP function. Molecular Cell 33.
Zeitschriftenartikel
118 (15), e2009329118 (2021)
The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs. Proceedings of the National Academy of Sciences of the USA 34.
Zeitschriftenartikel
28 (4), S. 382 - 387 (2021)
Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nature Structural and Molecular Biology 35.
Zeitschriftenartikel
10, e65381 (2021)
Evidence for additive and synergistic action of mammalian enhancers during cell fate determination. eLife 36.
Zeitschriftenartikel
81 (5), S. 1013 - 1026.e11 (2021)
Stress-induced nuclear condensation of NELF drives transcriptional downregulation. Molecular Cell 37.
Zeitschriftenartikel
81 (4), S. 830 - 844.e13 (2021)
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Molecular Cell 38.
Zeitschriftenartikel
40 (9), e107015 (2021)
Transcription activation depends on the length of the RNA polymerase II C‐terminal domain. EMBO Journal 39.
Zeitschriftenartikel
18 (2), S. 186 - 193 (2021)
Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells. Nature Methods 40.
Zeitschriftenartikel
371 (6526), S. 305 - 309 (2021)
Structure of a transcribing RNA polymerase II–U1 snRNP complex. Science 41.
Zeitschriftenartikel
12, 279 (2021)
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nature Communications 42.
Zeitschriftenartikel
12, 279 (2021)
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nature Communications 43.
Zeitschriftenartikel
27 (1), S. 49 - 53 (2021)
Coronavirus-Replikation: Mechanismus und Inhibition durch Remdesivir. Biospektrum 44.
Zeitschriftenartikel
17 (1), S. 47 - 56 (2021)
Permissive epigenomes endow reprogramming competence to transcriptional regulators. Nature Chemical Biology 45.
Zeitschriftenartikel
17 (1), e9873 (2021)
Transcriptionally active enhancers in human cancer cells. Molecular Systems Biology 46.
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Integrator is a genome-wide attenuator of non-productive transcription. Molecular Cell, in Press (2020)
47.
Zeitschriftenartikel
588 (7839), S. 712 - 716 (2020)
Small-molecule inhibitors of human mitochondrial DNA transcription. Nature 48.
Zeitschriftenartikel
36, S. 1 - 34 (2020)
Structural biology of RNA polymerase II transcription: 20 years on. Annual Review of Cell and Developmental Biology 49.
Zeitschriftenartikel
30 (9), S. 1332 - 1344 (2020)
Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms. Genome Research 50.
Zeitschriftenartikel
182 (4), S. 787 - 789 (2020)
Rosalind Franklin and the advent of molecular biology. Cell 51.
Zeitschriftenartikel
48 (14), S. 7712 - 7727 (2020)
CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. Nucleic Acids Research 52.
Zeitschriftenartikel
584 (7819), S. 154 - 156 (2020)
Structure of replicating SARS-CoV-2 polymerase. Nature 53.
Zeitschriftenartikel
369 (6503), S. 554 - 557 (2020)
In-cell architecture of an actively transcribing-translating expressome. Science 54.
Zeitschriftenartikel
52 (7), S. 719 - 727 (2020)
Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics 55.
Zeitschriftenartikel
52 (7), S. 655 - 661 (2020)
CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response. Nature Genetics 56.
Zeitschriftenartikel
27 (7), S. 668 - 677 (2020)
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 57.
Zeitschriftenartikel
9, e56178 (2020)
Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. eLife 58.
Zeitschriftenartikel
220, 103754 (2020)
An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 59.
Zeitschriftenartikel
580 (7805), S. 669 - 672 (2020)
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 60.
Zeitschriftenartikel
579 (7799), S. 448 - 451 (2020)
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 61.
Zeitschriftenartikel
594 (2), S. 207 - 208 (2020)
500 years after the first circumnavigation of the world: The efforts, rewards and drawbacks of exploration. FEBS Letters 62.
Zeitschriftenartikel
63 (2), S. 601 - 612 (2020)
Discovery of BAY-985, a highly selective TBK1/IKK epsilon inhibitor. Journal of Medicinal Chemistry 63.
Zeitschriftenartikel
30 (1), S. 4 - 14 (2020)
Mechanisms for active regulation of biomolecular condensates. Trends in Cell Biology 64.
Zeitschriftenartikel
577, S. 717 - 720 (2020)
Structure of the transcription coactivator SAGA. Nature 65.
Zeitschriftenartikel
27 (1), S. 8 - 13 (2020)
Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nature Structural and Molecular Biology 66.
Zeitschriftenartikel
179 (7), S. 1537 - 1550 (2019)
Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 67.
Zeitschriftenartikel
179 (7), S. 1525 - 1536 (2019)
Structural basis of poxvirus transcription: Transcribing and capping vaccinia complexes. Cell 68.
Zeitschriftenartikel
16, S. 1146 - 1152 (2019)
Real-time cryo-electron microscopy data preprocessing with Warp. Nature Methods 69.
Zeitschriftenartikel
47 (17), S. 9282 - 9295 (2019)
A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5 '-3 ' messenger RNA decay. Nucleic Acids Research 70.
Zeitschriftenartikel
10, 3863 (2019)
Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nature Communications 71.
Zeitschriftenartikel
116 (34), S. 16866 - 16871 (2019)
Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 72.
Zeitschriftenartikel
10 (1), 3603 (2019)
The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 73.
Zeitschriftenartikel
10 (1), 3138 (2019)
NASC-seq monitors RNA synthesis in single cells. Nature Communications 74.
Zeitschriftenartikel
294, S. 10663 - 10673 (2019)
Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 75.
Zeitschriftenartikel
10, 2885 (2019)
Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 76.
Zeitschriftenartikel
8, e47040 (2019)
Transcriptome maps of general eukaryotic RNA degradation factors. eLife 77.
Zeitschriftenartikel
74 (4), S. 674 - 687 (2019)
MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Molecular Cell 78.
Zeitschriftenartikel
294 (18), S. 7528 - 7536 (2019)
Yeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation. Journal of Biological Chemistry 79.
Zeitschriftenartikel
116 (20), S. 10048 - 10057 (2019)
Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 80.
Zeitschriftenartikel
8, e45056 (2019)
Global donor and acceptor splicing site kinetics in human cells. eLife 81.
Zeitschriftenartikel
10 (1), e01966-18 (2019)
Functional metagenomics reveals an overlooked diversity and novel features of soil-derived bacterial phosphatases and phytases. mBio 82.
Zeitschriftenartikel
176 (1-2), S. 182 - 197 (2019)
The implication of early chromatin changes in X chromosome inactivation. Cell 83.
Zeitschriftenartikel
73 (1), S. 97 - 106 (2019)
Promoter distortion and opening in the RNA polymerase II cleft. Molecular Cell 84.
Zeitschriftenartikel
573, S. 45 - 54 (2019)
Organization and regulation of gene transcription. Nature 85.
Zeitschriftenartikel
179 (4), S. 808 - 812 (2019)
Eukaryotic transcription turns 50. Cell 86.
Zeitschriftenartikel
9, 5432 (2018)
Structure of transcribing RNA polymerase II-nucleosome complex. Nature Communications 87.
Zeitschriftenartikel
46 (21), S. 11528 - 11538 (2018)
The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 88.
Zeitschriftenartikel
562 (7728), S. 538 - 544 (2018)
Transcription factor dimerization activates the p300 acetyltransferase. Nature 89.
Zeitschriftenartikel
562 (7725), S. 76 - 81 (2018)
The interaction landscape between transcription factors and the nucleosome. Nature 90.
Zeitschriftenartikel
25 (9), S. 833 - 840 (2018)
RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 91.
Zeitschriftenartikel
25 (9), S. 754 - 765 (2018)
Structural basis of mitochondrial transcription. Nature Structural and Molecular Biology 92.
Zeitschriftenartikel
560 (7720), S. 607 - 612 (2018)
Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 93.
Zeitschriftenartikel
560 (7720), S. 601 - 606 (2018)
Structure of paused transcription complex Pol II–DSIF–NELF. Nature 94.
Zeitschriftenartikel
560 (7719), S. 494 - 498 (2018)
RNA velocity of single cells. Nature 95.
Zeitschriftenartikel
293 (19), S. 7189 - 7194 (2018)
Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 96.
Zeitschriftenartikel
47, S. 425 - 446 (2018)
Distinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 97.
Zeitschriftenartikel
47, S. 17 - 22 (2017)
Conserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 98.
Zeitschriftenartikel
6, e32493 (2017)
The structure of the COPI coat determined within the cell. eLife 99.
Zeitschriftenartikel
171 (5), S. 1072 - 1081 (2017)
Structural basis of mitochondrial transcription initiation. Cell