Publications
Journal Article (297)
1.
Journal Article
37, pp. 1830 - 1841 (2023)
Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells. Leukemia 2.
Journal Article
83 (13), pp. 2240 - 2257 (2023)
ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts. Molecular Cell 3.
Journal Article
30, pp. 991 - 1000 (2023)
The Mediator complex regulates enhancer-promoter interactions. Nature Structural and Molecular Biology 4.
Journal Article
83 (11), pp. 1798 - 1809.e7 (2023)
Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Molecular Cell 5.
Journal Article
617, pp. 842 - 850 (2023)
Structural basis of catalytic activation in human splicing. Nature 6.
Journal Article
Mediator structure and function in transcription initiation. Biological Chemistry, aop (2023)
7.
Journal Article
120 (15), e2220542120 (2023)
Yeast PIC-mediator structure with RNA polymerase II C-terminal domain. Proceedings of the National Academy of Sciences of the United States of America 8.
Journal Article
9 (9), eadf178 (2023)
Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins. Science Advances 9.
Journal Article
30, pp. 226 - 232 (2023)
Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nature Structural and Molecular Biology 10.
Journal Article
10 (Part 1), pp. 4 - 5 (2023)
Towards automating single-particle cryo-EM data acquisition. IUCRJ 11.
Journal Article
29, pp. 1159 - 1169 (2022)
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nature Structural and Molecular Biology 12.
Journal Article
13 (1), 6810 (2022)
The 3D structure of lipidic fibrils of α-synuclein. Nature Communications 13.
Journal Article
13 (1), 6182 (2022)
Sublinear scaling of the cellular proteome with ploidy. Nature Communications 14.
Journal Article
610 (7930), pp. 205 - 211 (2022)
Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature 15.
Journal Article
46, 101580 (2022)
Multivalent ACE2 engineering-A promising pathway for advanced coronavirus nanomedicine development. Nano Today 16.
Journal Article
5 (1), 1040 (2022)
Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology 17.
Journal Article
14, pp. 1278 - 1285 (2022)
Molecular interactions of FG nucleoporin repeats at high resolution. Nature Chemistry 18.
Journal Article
13, pp. 5385 - 5394 (2022)
The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils. Nature Communications 19.
Journal Article
82 (17), pp. 3126 - 3134.e7 (2022)
Structure of a backtracked hexasomal intermediate of nucleosome transcription. Molecular Cell 20.
Journal Article
61 (15), pp. 1633 - 1641 (2022)
HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry 21.
Journal Article
11, e71533 (2022)
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. eLife 22.
Journal Article
29 (5), pp. 493 - 501 (2022)
Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nature Structural and Molecular Biology 23.
Journal Article
54 (3), pp. 283 - 294 (2022)
Sequence determinants of human gene regulatory elements. Nature Genetics 24.
Journal Article
17 (2), pp. 445 - 475 (2022)
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture. Nature Protocols 25.
Journal Article
12 (5), jkac054 (2022)
RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. G3: Genes, Genomes, Genetics 26.
Journal Article
18 (1), e10407 (2022)
Distinct transcription kinetics of pluripotent cell states. Molecular Systems Biology 27.
Journal Article
374 (6569), pp. 883 - 887 (2021)
Structural basis of Integrator-mediated transcription regulation. Science 28.
Journal Article
598 (7880), pp. 368 - 372 (2021)
Structural basis of human transcription–DNA repair coupling. Nature 29.
Journal Article
49 (18), pp. 10747 - 10755 (2021)
Structure of an inactive RNA polymerase II dimer. Nucleic Acids Research 30.
Journal Article
27 (10), pp. 1281 - 1290 (2021)
The total mRNA concentration buffering system in yeast is global rather than gene-specific. RNA 31.
Journal Article
40 (19), e107985 (2021)
Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 32.
Journal Article
28 (9), pp. 713 - 723 (2021)
Structural basis of RNA processing by human mitochondrial RNase P. Nature Structural and Molecular Biology 33.
Journal Article
28 (9), pp. 704 - 705 (2021)
AlphaFold2 and the future of structural biology. Nature Structural and Molecular Biology 34.
Journal Article
28 (9), pp. 740 - 746 (2021)
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nature Structural and Molecular Biology 35.
Journal Article
4, 999 (2021)
The structure of a dimeric form of SARS-CoV-2 polymerase. Communications Biology 36.
Journal Article
81 (15), pp. 3096 - 3109.e8 (2021)
Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo. Molecular Cell 37.
Journal Article
118 (30), e2108859118 (2021)
Structures and implications of TBP–nucleosome complexes. Proceedings of the National Academy of Sciences of the USA 38.
Journal Article
184 (15), pp. 4064 - 4072.e28 (2021)
Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening. Cell 39.
Journal Article
81 (16), pp. 3386 - 3399.e10 (2021)
Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 40.
Journal Article
594 (7861), pp. 124 - 128 (2021)
Structures of mammalian RNA polymerase II pre-initiation complexes. Nature 41.
Journal Article
594 (7861), pp. 129 - 133 (2021)
Structure of the human Mediator-RNA polymerase II pre-initiation complex. Nature 42.
Journal Article
296, 100734 (2021)
The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 43.
Journal Article
12, 3232 (2021)
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing. Nature Communications 44.
Journal Article
4, 606 (2021)
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2. Communications Biology 45.
Journal Article
81 (9), pp. 1920 - 1934.e9 (2021)
Efficient RNA polymerase II pause release requires U2 snRNP function. Molecular Cell 46.
Journal Article
118 (15), e2009329118 (2021)
The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs. Proceedings of the National Academy of Sciences of the USA 47.
Journal Article
28 (4), pp. 382 - 387 (2021)
Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nature Structural and Molecular Biology 48.
Journal Article
10, e65381 (2021)
Evidence for additive and synergistic action of mammalian enhancers during cell fate determination. eLife 49.
Journal Article
81 (5), pp. 1013 - 1026.e11 (2021)
Stress-induced nuclear condensation of NELF drives transcriptional downregulation. Molecular Cell 50.
Journal Article
81 (4), pp. 830 - 844.e13 (2021)
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Molecular Cell