Publications
Journal Article (324)
1.
Journal Article
122 (10), e2419854122 (2025)
Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr. Proceedings of the National Academy of Sciences of the United States of America 2.
Journal Article
217 (1), 108179 (2025)
Cryo-iCLEM: Cryo correlative light and electron microscopy with immersion objectives. Journal of Structural Biology 3.
Journal Article
Promoter-proximal RNA polymerase II termination regulates transcription during human cell type transition. Nature Structural & Molecular Biology (2025)
4.
Journal Article
32, pp. 339 - 345 (2025)
Mechanism of polyadenylation-independent RNA polymerase II termination. Nature Structural & Molecular Biology 5.
Journal Article
187 (25), pp. 7107 - 7125.e25 (2024)
STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair. Cell 6.
Journal Article
12, 187 (2024)
Strain-resolved de-novo metagenomic assembly of viral genomes and microbial 16S rRNAs. Microbiome 7.
Journal Article
84 (18), pp. 3423 - 3437.e8 (2024)
Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Molecular Cell 8.
Journal Article
63 (32), e202404645 (2024)
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2. Angewandte Chemie International Edition 9.
Journal Article
84 (12), pp. 2287 - 2303.e10 (2024)
CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release. Molecular Cell 10.
Journal Article
84 (11), pp. 2053 - 2069.e9 (2024)
FACT maintains chromatin architecture and thereby stimulates RNA polymerase II pausing during transcription in vivo. Molecular Cell 11.
Journal Article
20 (5), e1012059 (2024)
Nuclear export is a limiting factor in eukaryotic mRNA metabolism. PLOS Computational Biology 12.
Journal Article
15, 3797 (2024)
Impact of distinct FG nucleoporin repeats on Nup98 self-association. Nature Communications 13.
Journal Article
629, pp. 219 - 227 (2024)
Structural basis of Integrator-dependent RNA polymerase II termination. Nature 14.
Journal Article
84 (9), pp. 1699 - 1710.e6 (2024)
Three-step mechanism of promoter escape by RNA polymerase II. Molecular Cell 15.
Journal Article
31, pp. 393 - 394 (2024)
Good reasons for structural biology. Nature Structural & Molecular Biology 16.
Journal Article
31, pp. 536 - 547 (2024)
Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair. Nature Structural & Molecular Biology 17.
Journal Article
56, pp. 483 - 492 (2024)
In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization. Nature Genetics 18.
Journal Article
15, 1297 (2024)
Cryo-EM structures of lipidic fibrils of amyloid-β (1-40). Nature Communications 19.
Journal Article
31, pp. 364 - 377 (2024)
Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1. Nature Structural & Molecular Biology 20.
Journal Article
15, 317 (2024)
Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail. Nature Communications 21.
Journal Article
31 (1), e9, pp. 127 - 147 (2024)
Highly cooperative chimeric super-SOX induces naive pluripotency across species. Cell Stem Cell 22.
Journal Article
84, 102766 (2024)
RNA polymerase II elongation factors use conserved regulatory mechanisms. Current Opinion in Structural Biology 23.
Journal Article
52 (2), pp. 793 - 802 (2024)
Genome organization across scales: mechanistic insights from in vitro reconstitution studies. Biochemical Society Transactions 24.
Journal Article
624 (7990), pp. 173 - 181 (2023)
MSL2 ensures biallelic gene expression in mammals. Nature 25.
Journal Article
30, pp. 1925 - 1935 (2023)
Structure of the transcribing RNA polymerase II–Elongin complex. Nature Structural & Molecular Biology 26.
Journal Article
37, pp. 1830 - 1841 (2023)
Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells. Leukemia 27.
Journal Article
83 (14), pp. 2464 - 2477.e5 (2023)
Structural insights into human co-transcriptional capping. Molecular Cell 28.
Journal Article
83 (13), pp. 2240 - 2257 (2023)
ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts. Molecular Cell 29.
Journal Article
30, pp. 991 - 1000 (2023)
The Mediator complex regulates enhancer-promoter interactions. Nature Structural and Molecular Biology 30.
Journal Article
83 (11), pp. 1798 - 1809.e7 (2023)
Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Molecular Cell 31.
Journal Article
617, pp. 842 - 850 (2023)
Structural basis of catalytic activation in human splicing. Nature 32.
Journal Article
Mediator structure and function in transcription initiation. Biological Chemistry, aop (2023)
33.
Journal Article
120 (15), e2220542120 (2023)
Yeast PIC-mediator structure with RNA polymerase II C-terminal domain. Proceedings of the National Academy of Sciences of the United States of America 34.
Journal Article
9 (9), eadf178 (2023)
Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins. Science Advances 35.
Journal Article
30, pp. 226 - 232 (2023)
Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nature Structural and Molecular Biology 36.
Journal Article
10 (Part 1), pp. 4 - 5 (2023)
Towards automating single-particle cryo-EM data acquisition. IUCRJ 37.
Journal Article
14 (1), 5979 (2023)
Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II. Nature Communications 38.
Journal Article
29, pp. 1159 - 1169 (2022)
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nature Structural and Molecular Biology 39.
Journal Article
13 (1), 6810 (2022)
The 3D structure of lipidic fibrils of α-synuclein. Nature Communications 40.
Journal Article
14, pp. 1278 - 1285 (2022)
Molecular interactions of FG nucleoporin repeats at high resolution. Nature Chemistry 41.
Journal Article
13 (1), 6182 (2022)
Sublinear scaling of the cellular proteome with ploidy. Nature Communications 42.
Journal Article
610 (7930), pp. 205 - 211 (2022)
Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature 43.
Journal Article
46, 101580 (2022)
Multivalent ACE2 engineering-A promising pathway for advanced coronavirus nanomedicine development. Nano Today 44.
Journal Article
5 (1), 1040 (2022)
Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology 45.
Journal Article
13, pp. 5385 - 5394 (2022)
The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils. Nature Communications 46.
Journal Article
82 (17), pp. 3126 - 3134.e7 (2022)
Structure of a backtracked hexasomal intermediate of nucleosome transcription. Molecular Cell 47.
Journal Article
61 (15), pp. 1633 - 1641 (2022)
HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry 48.
Journal Article
11, e71533 (2022)
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. eLife 49.
Journal Article
29 (5), pp. 493 - 501 (2022)
Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nature Structural & Molecular Biology 50.
Journal Article
54 (3), pp. 283 - 294 (2022)
Sequence determinants of human gene regulatory elements. Nature Genetics