Publications

101.

Journal Article

La Manno, G.; Soldatov, R.; Zeisel, A.; Braun, E.; Hochgerner, H.; Petukhov, V.; Lidschreiber, K.; Kastriti, M. E.; Lönnerberg, P.; Furlan, A. et al.; Fan, J.; Borm, L. E.; Liu, Z.; van Bruggen, D.; Guo, J.; He, X.; Barker, R.; Sundström, E.; Castelo-Branco, G.; Cramer, P.; Adameyko, I.; Linnarsson, S.; Kharchenko, P. V.: RNA velocity of single cells. Nature 560 (7719), pp. 494 - 498 (2018)

MPG.PuRe

102.

Journal Article

Liu, X.; Farnung, L.; Wigge, C.; Cramer, P.: Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 293 (19), pp. 7189 - 7194 (2018)

MPG.PuRe

103.

Journal Article

Engel, C.; Neyer, S.; Cramer, P.: Distinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 47, pp. 425 - 446 (2018)

MPG.PuRe

104.

Journal Article

Hantsche, M.; Cramer, P.: Conserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 47, pp. 17 - 22 (2017)

MPG.PuRe

105.

Journal Article

Bykov, Y. S.; Schaffer, M.; Dodonova, S. O.; Albert, S.; Plitzko, J. M.; Baumeister, W.; Engel, B. D.; Briggs, J. A. G.: The structure of the COPI coat determined within the cell. eLife 6, e32493 (2017)

MPG.PuRe

106.

Journal Article

Hillen, H. S.; Morozov, Y. I.; Sarfallah, A.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription initiation. Cell 171 (5), pp. 1072 - 1081 (2017)

MPG.PuRe

107.

Journal Article

Hillen, H. S.; Parshin, A. V.; Agaronyan, K.; Morozov, Y. I.; Graber, J. J.; Chernev, A.; Schwinghammer, K.; Urlaub, H.; Anikin, M.; Cramer, P. et al.; Temiakov, D.: Mechanism of transcription anti-termination in human mitochondria. Cell 171 (5), pp. 1082 - 1093 (2017)

MPG.PuRe

108.

Journal Article

Malvezzi, S.; Farnung, L.; Aloisi, C. M. N.; Angelov, T.; Cramer, P.; Sturla, S. J.: Mechanism of RNA polymerase II stalling by DNA alkylation. Proceedings of the National Academy of Sciences of the United States of America 114 (46), pp. 12172 - 12177 (2017)

MPG.PuRe

109.

Journal Article

Schilbach, S.; Hantsche, M.; Tegunov, D.; Dienemann, C.; Wigge, C.; Urlaub, H.; Cramer, P.: Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), pp. 204 - 209 (2017)

MPG.PuRe

110.

Journal Article

Cheng, J.; Maier, K. C.; Avsec, Z.; Rus, P.; Gagneur, J.: Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. RNA 23 (11), pp. 1648 - 1659 (2017)

MPG.PuRe

111.

Journal Article

Farnung, L.; Vos, S. M.; Wigge, C.; Cramer, P.: Nucleosome-Chd1 structure and implications for chromatin remodelling. Nature 550 (7677), pp. 539 - 542 (2017)

MPG.PuRe

112.

Journal Article

Gressel, S.; Schwalb, B.; Decker, T. M.; Qin, W.; Leonhardt, H.; Eick, D.; Cramer, P.: CDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 6, e29736 (2017)

MPG.PuRe

113.

Journal Article

Bernecky, C.; Plitzko, J. M.; Cramer, P.: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular Biology 24 (10), pp. 809 - 815 (2017)

MPG.PuRe

Full

114.

Journal Article

Glaser, L. V.; Rieger, S.; Thumann, S.; Beer, S.; Kuklik-Roos, C.; Martin, D. E.; Maier, K. C.; Harth-Hertle, M. L.; Grüning, B.; Backofen, R. et al.; Krebs, S.; Blum, H.; Zimmer, R.; Erhard, F.; Kempkes, B.: EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells. PLoS Pathogens 13 (10), e1006664 (2017)

MPG.PuRe

115.

Journal Article

Cramer, P.: Structural molecular biology - A personal reflection on the occasion of John Kendrew's 100th birthday. Journal of Molecular Biology 429 (17), pp. 2603 - 2610 (2017)

MPG.PuRe

116.

Journal Article

Boratyn, E.; Nowak, I.; Durbas, M.; Horwacik, I.; Sawicka, A.; Rokita, H.: MCPIP1 exogenous overexpression inhibits pathways regulating MYCN oncoprotein stability in neuroblastoma. Journal of Cellular Biochemistry 118 (7), pp. 1741 - 1755 (2017)

MPG.PuRe

117.

Journal Article

Dodonova, S. O.; Aderhold, P.; Kopp, J.; Ganeva, I.; Röhling, S.; Hagen, W. J. H.; Sinning, I.; Wieland, F.; Briggs, J. A. G.: 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. eLife 6, e26691 (2017)

MPG.PuRe

118.

Journal Article

Xu, Y.; Bernecky, C.; Lee, C. T.; Maier, K. C.; Schwalb, B.; Tegunov, D.; Plitzko, J. M.; Urlaub, H.; Cramer, P.: Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex. Nature Communications 8, 15741 (2017)

MPG.PuRe

119.

Journal Article

Battaglia, S.; Lidschreiber, M.; Bäjen, C.; Torkler, P.; Vos, S. M.; Cramer, P.: RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. eLife 6, e25637 (2017)

MPG.PuRe

120.

Journal Article

Nozawa, K.; Schneider, T. R.; Cramer, P.: Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nature 545 (7653), pp. 248 - 251 (2017)

MPG.PuRe

121.

Journal Article

Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R.; Cramer, P.: Architecture of a transcribing-translating expressome. Science 356 (6334), pp. 194 - 197 (2017)

MPG.PuRe

122.

Journal Article

Bäjen, C.; Andreani, J.; Torkler, P.; Battaglia, S.; Schwalb, B.; Lidschreiber, M.; Maier, K. C.; Boltendahl, A.; Rus, P.; Esslinger, S. et al.; Söding, J.; Cramer, P.: Genome-wide analysis of RNA polymerase II termination at protein-coding genes. Molecular Cell 66 (1), pp. 38 - 49 (2017)

MPG.PuRe

123.

Journal Article

Shetty, A.; Kallgren, S. P.; Demel, C.; Maier, K. C.; Spatt, D.; Alver, B. H.; Cramer, P.; Park, P. J.; Winston, F.: Spt5 plays vital roles in the control of sense and antisense transcription elongation. Molecular Cell 66 (6), pp. 77 - 88 (2017)

MPG.PuRe

124.

Journal Article

Wittmann, S.; Renner, M.; Watts, B. R.; Adams, O.; Huseyin, M.; Baejen, C.; El Omari, K.; Kilchert, C.; Heo, D. H.; Kecman, T. et al.; Cramer, P.; Grimes, J. M.; Vasiljeva, L.: The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nature Communications 8, 14861 (2017)

MPG.PuRe

125.

Journal Article

Engel, C.; Gubbey, T.; Neyer, S.; Sainsbury, S.; Oberthür, C.; Bäjen, C.; Bernecky, C.; Cramer, P.: Structural basis of RNA polymerase I transcription initiation. Cell 169 (1), pp. 120 - 131 (2017)

MPG.PuRe

126.

Journal Article

Michel, M.; Demel, C.; Zacher, B.; Schwalb, B.; Krebs, S.; Blum, H.; Gagneur, J.; Cramer, P.: TT-seq captures enhancer landscapes immediately after T-cell stimulation. Molecular Systems Biology 13 (3), 920 (2017)

MPG.PuRe

127.

Journal Article

Danev , R.; Tegunov, D.; Baumeister, W.: Using the Volta phase plate with defocus for cryo-EM single particle analysis. eLife 6, e23006 (2017)

MPG.PuRe

128.

Journal Article

Zacher, B.; Michel, M.; Schwalb, B.; Cramer, P.; Tresch, A.; Gagneur, J.: Accurate promoter and enhancer identification in 127 ENCODE and roadmap epigenomics cell types and tissues by GenoSTAN. PLoS One 12 (1), e0169249 (2017)

MPG.PuRe

129.

Journal Article

Hantsche, M.; Cramer, P.: Structural basis of transcription: 10 years after the Nobel Prize in Chemistry. Angewandte Chemie International Edition 55 (52), pp. 15972 - 15981 (2016)

MPG.PuRe

130.

Journal Article

Neyer, S.; Kunz, M.; Geiss, C.; Hantsche, M.; Hodirnau, V. V.; Seybert, A.; Engel, C.; Scheffer, M. P.; Cramer, P.; Frangakis, A. S.: Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature 540 (7634), pp. 607 - 610 (2016)

MPG.PuRe

131.

Journal Article

Fitz, V.; Shin, J.; Ehrlich, C.; Farnung, L.; Cramer, P.; Zaburdaev, V.; Grill, S. W.: Nucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 113 (45), pp. 12733 - 12738 (2016)

MPG.PuRe

132.

Journal Article

Hillenbrand, P.; Maier, K. C.; Cramer, P.; Gerland, U.: Inference of gene regulation functions from dynamic transcriptome data. eLife 5, e12188 (2016)

MPG.PuRe

133.

Journal Article

Shao, W.; Zumer, K.; Fujinaga, K.; Peterlin, B. M.: FBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 291 (34), pp. 17953 - 17963 (2016)

MPG.PuRe

134.

Journal Article

Cramer, P.: Structure determination of transient transcription complexes. Biochemical Society Transactions 44 (4), pp. 1177 - 1182 (2016)

MPG.PuRe

135.

Journal Article

Engel, C.; Plitzko, J.; Cramer, P.: RNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 7, 12129 (2016)

MPG.PuRe

136.

Journal Article

Plaschka, C.; Nozawa, K.; Cramer, P.: Mediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 428 (12), pp. 2569 - 2574 (2016)

MPG.PuRe

137.

Journal Article

Vos, S. M.; Pöllmann, D.; Caizzi, L.; Hofmann, K. B.; Rombaut, P.; Zimniak, T.; Herzog, F.; Cramer, P.: Architecture and RNA binding of the human negative elongation factor. eLife 5, e14981 (2016)

MPG.PuRe

138.

Journal Article

Schwalb, B.; Michel, M.; Zacher, B.; Frühauf, K.; Demel, C.; Tresch, A.; Gagneur, J.; Cramer, P.: TT-seq maps the human transient transcriptome. Science 352 (6290), pp. 1225 - 1228 (2016)

MPG.PuRe

139.

Journal Article

Plaschka, C.; Hantsche, M.; Dienemann, C.; Burzinski, C.; Plitzko, J.; Cramer, P.: Transcription initiation complex structures elucidate DNA opening. Nature 533 (7603), pp. 353 - 358 (2016)

MPG.PuRe

140.

Journal Article

Lisica, A.; Engel, C.; Jahnel, M.; Roldán, É.; Galburt, E. A.; Cramer, P.; Grill, S. W.: Mechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 113 (11), pp. 2946 - 2951 (2016)

MPG.PuRe

141.

Journal Article

Niesser, J.; Wagner, F. R.; Kostrewa, D.; Mühlbacher, W.; Cramer, P.: Structure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 36 (5), pp. 820 - 831 (2016)

MPG.PuRe

142.

Journal Article

Eser, P.; Wachutka, L.; Maier, K. C.; Demel, C.; Boroni, M.; Iyer, S.; Cramer, P.; Gagneur, J.: Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 12 (2), 857 (2016)

MPG.PuRe

143.

Journal Article

Bernecky, C.; Herzog, F.; Baumeister, W.; Plitzko, J. M.; Cramer, P.: Structure of transcribing mammalian RNA polymerase II. Nature 529 (7587), pp. 551 - 554 (2016)

MPG.PuRe

144.

Journal Article

Schüller, R.; Forné, I.; Straub, T.; Schreieck, A.; Texier, Y.; Shah, N.; Decker, T. M.; Cramer, P.; Imhof, A.; Eick, D.: Heptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 61 (2), pp. 305 - 314 (2016)

MPG.PuRe

145.

Journal Article

Mühlbacher, W.; Mayer, A.; Sun, M.; Remmert, M.; Cheung, A. C. M.; Niesser, J.; Söding, J.; Cramer, P.: Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 83 (10), pp. 1849 - 1858 (2015)

MPG.PuRe

146.

Journal Article

Kostrewa, D.; Kuhn, C. D.; Engel, C.; Cramer, P.: An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 71 (9), pp. 1850 - 1855 (2015)

MPG.PuRe

147.

Journal Article

Martinez-Rucobo, F. W.; Kohler, R.; Waterbeemd, M. v. d.; Heck, A. J.; Hemann, M.; Herzog, F.; Stark, H.; Cramer, P.: Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 58 (6), pp. 1079 - 1089 (2015)

MPG.PuRe

148.

Journal Article

Morozov, Y. I.; Parshin, A. V.; Agaronyan, K.; Cheung, A. C.; Anikin, M.; Cramer, P.; Temiakov, D.: A model for transcription initiation in human mitochondria. Nucleic Acids Research 43 (7), pp. 3726 - 3735 (2015)

MPG.PuRe

149.

Journal Article

Sainsbury, S.; Bernecky, C.; Cramer, P.: Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 16 (3), pp. 129 - 143 (2015)

MPG.PuRe

150.

Journal Article

Plaschka, C.; Larivière, L.; Wenzeck, L.; Seizl, M.; Hemann, M.; Tegunov, D.; Petrotchenko, E. V.; Borchers, C. H.; Baumeister, W.; Herzog, F. et al.; Villa, E.; Cramer, P.: Architecture of the RNA polymerase II–Mediator core initiation complex. Nature 518 (7539), pp. 376 - 380 (2015)

MPG.PuRe

151.

Journal Article

Borck, G.; Hög, F.; Dentici, M. L.; Tan, P. L.; Sowada, N.; Medeira, A.; Gueneau, L.; Thiele, H.; Kousi, M.; Lepri, F. et al.; Wenzeck, L.; Blumenthal, I.; Radicioni, A.; Schwarzenberg, T. L.; Mandriani, B.; Fischetto, R.; Morris-Rosendahl, D. J.; Altmüller, J.; Reymond, A.; Nürnberg, P.; Merla, G.; Dallapiccola, B.; Katsanis, N.; Cramer, P.; Kubisch, C.: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 25 (2), pp. 155 - 166 (2015)

MPG.PuRe

152.

Journal Article

Zacher, B.; Lidschreiber, M.; Cramer, P.; Gagneur, J.; Tresch, A.: Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 10 (12), 768 (2014)

MPG.PuRe

153.

Journal Article

Cramer, P.: A tale of chromatin and transcription in 100 structures. Cell 159 (5), pp. 985 - 994 (2014)

MPG.PuRe

154.

Journal Article

Bäjen, C.; Torkler, P.; Gressel, S.; Essig, K.; Söding, J.; Cramer, P.: Transcriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 55 (5), pp. 745 - 757 (2014)

MPG.PuRe

155.

Journal Article

Tudek, A.; Porrua, O.; Kabzinski, T.; Lidschreiber, M.; Kubicek, K.; Fortova, A.; Lacroute, F.; Vanakova, S.; Cramer, P.; Stefl, R. et al.; Libri, D.: Molecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 55 (3), pp. 467 - 481 (2014)

MPG.PuRe

156.

Journal Article

Mühlbacher, W.; Sainsbury, S.; Hemann, M.; Hantsche, M.; Neyer, S.; Herzog, F.; Cramer, P.: Conserved architecture of the core RNA polymerase II initiation complex. Nature Communications 5, 4310 (2014)

MPG.PuRe

157.

Journal Article

Sydow, J. F.; Lipsmeier, F.; Larraillet, V.; Hilger, M.; Mautz, B.; Mølhøj, M.; Kuentzer, J.; Klostermann, S.; Schoch, J.; Voelger, H. R. et al.; Regula, J. T.; Cramer, P.; Papadimitriou, A.; Kettenberger, H.: Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions. PLoS One 9 (6), e100736 (2014)

MPG.PuRe

158.

Journal Article

Schulz, D.; Pirkl, N.; Lehmann, E.; Cramer, P.: Rpb4 functions mainly in mRNA synthesis by RNA polymerase II. Journal of Biological Chemistry 289 (25), pp. 17446 - 17452 (2014)

MPG.PuRe

159.

Journal Article

Hirschmann, W. D.; Westendorf, H.; Mayer, A.; Cannarozzi, G.; Cramer, P.; Jansen, R. P.: Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Research 42 (6), pp. 4043 - 4055 (2014)

MPG.PuRe

160.

Journal Article

Morozov, Y. I.; Agaronyan, K.; Cheung, A. C. M.; Anikin, M.; Cramer, P.; Temiakov, D.: A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Research 42 (6), pp. 3884 - 3893 (2014)

MPG.PuRe

161.

Journal Article

Schreieck, A.; Easter, A. D.; Etzold, S.; Wiederhold, K.; Lidschreiber, M.; Cramer, P.; Passmore, L. A.: RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7. Nature Structural and Molecular Biology 21 (2), pp. 175 - 179 (2014)

MPG.PuRe

162.

Journal Article

Eser, P.; Demel, C.; Maier, K. C.; Schwalb, B.; Pirkl, N.; Martin, D. E.; Cramer, P.; Tresch, A.: Periodic mRNA synthesis and degradation co-operate during cell cycle gene expression. Molecular Systems Biology 10 (1), 717 (2014)

MPG.PuRe

163.

Journal Article

Meinel, D. M.; Burkert-Kautzsch, C.; Kieser, A.; O'Duibhir, E.; Siebert, M.; Mayer, A.; Cramer, P.; Söding, J.; Holstege, F. C.; Sträßer, K.: Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II. PLoS Genetics 9 (11), e1003914 (2013)

MPG.PuRe

164.

Journal Article

Schulz, D.; Schwalb, B.; Kiesel, A.; Baejen, C.; Torkler, P.; Gagneur, J.; Söding, J.; Cramer, P.: Transcriptome surveillance by selective termination of noncoding RNA synthesis. Cell 155 (5), pp. 1075 - 1087 (2013)

MPG.PuRe

165.

Journal Article

Heo, D.-h.; Yoo, I.; Kong, J.; Lidschreiber, M.; Mayer, A.; Choi, B.-Y.; Hahn, Y.; Cramer, P.; Buratowski, S.; Kim, M.: The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. Journal of Biological Chemistry 288 (51), pp. 36676 - 36690 (2013)

MPG.PuRe

166.

Journal Article

Engel, C.; Sainsbury, S.; Cheung, A. C.; Kostrewa, D.; Cramer, P.: RNA polymerase I structure and transcription regulation. Nature 502 (7473), pp. 650 - 655 (2013)

MPG.PuRe

167.

Journal Article

Sun, M.; Schwalb, B.; Pirkl, N.; Maier, K. C.; Schenk, A.; Failmezger, H.; Tresch, A.; Cramer, P.: Global analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levels. Molecular cell 52 (1), pp. 52 - 62 (2013)

MPG.PuRe

168.

Journal Article

Schwinghammer, K.; Cheung, A. C. M.; Morozov, Y. I.; Agaronyan, K.; Temiakov, D.; Cramer, P.: Structure of human mitochondrial RNA polymerase elongation complex. Nature Structural and Molecular Biology 20 (11), pp. 1298 - 1303 (2013)

MPG.PuRe

169.

Journal Article

Kinkelin, K.; Wozniak, G. G.; Rothbart, S. B.; Lidschreiber, M.; Strahl, B. D.; Cramer, P.: Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proceedings of the National Academy of Sciences of the USA 110 (38), pp. 15277 - 15282 (2013)

MPG.PuRe

170.

Journal Article

Larivière, L.; Plaschka, C.; Seizl, M.; Petrotchenko, E. V.; Wenzeck, L.; Borchers, C. H.; Cramer, P.: Model of the Mediator middle module based on protein cross-linking. Nucleic Acids Research 41 (20), pp. 9266 - 9273 (2013)

MPG.PuRe

171.

Journal Article

Lidschreiber, M.; Leike, K.; Cramer, P.: Cap completion and C-terminal repeat domain kinase recruitment underlie the initiation-elongation transition of RNA polymerase II. Molecular and cellular biology 33 (19), pp. 3805 - 3816 (2013)

MPG.PuRe

172.

Journal Article

Fouqueau, T.; Zeller, M. E.; Cheung, A. C.; Cramer, P.; Thomm, M.: The RNA polymerase trigger loop functions in all three phases of the transcription cycle. Nucleic acids research 41 (14), pp. 7048 - 7059 (2013)

MPG.PuRe

173.

Journal Article

Michel, M.; Cramer, P.: Transitions for regulating early transcription. Cell 153 (5), pp. 943 - 944 (2013)

MPG.PuRe

174.

Journal Article

Esslinger, S. M.; Schwalb, B.; Helfer, S.; Michalik, K. M.; Witte, H.; Maier, K. C.; Martin, D.; Michalke, B.; Tresch, A.; Cramer, P. et al.; Förstemann, K.: Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan. RNA Biology 10 (6), pp. 1042 - 1056 (2013)

MPG.PuRe

175.

Journal Article

Bernecky, C.; Cramer, P.: Struggling to let go: A non‐coding RNA directs its own extension and destruction. EMBO Journal 32 (6), pp. 771 - 772 (2013)

MPG.PuRe

176.

Journal Article

Sainsbury, S.; Niesser, J.; Cramer, P.: Structure and function of the initially transcribing RNA polymerase II–TFIIB complex. Nature 493 (7432), pp. 437 - 440 (2013)

MPG.PuRe

177.

Journal Article

Martinez-Rucobo, F. W.; Cramer, P.: Structural basis of transcription elongation. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1829 (1), pp. 9 - 19 (2013)

MPG.PuRe

178.

Journal Article

Larivière, L.; Plaschka, C.; Seizl, M.; Wenzeck, L.; Kurth, F.; Cramer, P.: Structure of the Mediator head module. Nature 492 (7429), pp. 448 - 451 (2012)

MPG.PuRe

179.

Journal Article

Miller, C.; Matic, I.; Maier, K. C.; Schwalb, B.; Roether, S.; Strässer, K.; Tresch, A.; Mann, M.; Cramer, P.: Mediator phosphorylation prevents stress response transcription during non-stress conditions. Journal of Biological Chemistry 287 (53), pp. 44017 - 44026 (2012)

MPG.PuRe

180.

Journal Article

Wu, C.-C.; Herzog, F.; Jennebach, S.; Lin, Y.-C.; Pai, C.-Y.; Aebersold, R.; Cramer, P.; Chen, H.-T.: RNA polymerase III subunit architecture and implications for open promoter complex formation. Proceedings of the National Academy of Sciences of the USA 109 (47), pp. 19232 - 19237 (2012)

MPG.PuRe

181.

Journal Article

Dümcke, S.; Seizl, M.; Etzold, S.; Pirkl, N.; Martin, D. E.; Cramer, P.; Tresch, A.: One Hand Clapping: detection of condition-specific transcription factor interactions from genome-wide gene activity data. Nucleic Acids Research 40 (18), pp. 8883 - 8892 (2012)

MPG.PuRe

182.

Journal Article

Mayer, A.; Heidemann, M.; Lidschreiber, M.; Schreieck, A.; Sun, M.; Hintermair, C.; Kremmer, E.; Eick, D.; Cramer, P.: CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II. Science 336 (6089), pp. 1723 - 1725 (2012)

MPG.PuRe

183.

Journal Article

Cheung, A. C. M.; Cramer, P.: A movie of RNA polymerase II transcription. Cell 149 (7), pp. 1431 - 1437 (2012)

MPG.PuRe

184.

Journal Article

Niederberger, T.; Etzold, S.; Lidschreiber, M.; Maier, K. C.; Martin, D. E.; Fröhlich, H.; Cramer, P.; Tresch, A.: MC EMiNEM maps the interaction landscape of the Mediator. PLoS Computational Biology 8 (6), e1002568 (2012)

MPG.PuRe

185.

Journal Article

Treutlein, B.; Muschielok, A.; Andrecka, J.; Jawhari, A.; Buchen, C.; Kostrewa, D.; Hög, F.; Cramer, P.; Michaelis, J.: Dynamic architecture of a minimal RNA polymerase II open promoter complex. Molecular Cell 46 (2), pp. 136 - 146 (2012)

MPG.PuRe

186.

Journal Article

Walmacq, C.; Cheung, A. C. M.; Kireeva, M. L.; Lubkowska, L.; Ye, C.; Gotte, D.; Strathern, J. N.; Carell, T.; Cramer, P.; Kashlev, M.: Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Molecular Cell 46 (1), pp. 18 - 29 (2012)

MPG.PuRe

187.

Journal Article

Sun, M.; Schwalb, B.; Schulz, D.; Pirkl, N.; Etzold, S.; Larivière, L.; Maier, K. C.; Seizl, M.; Tresch, A.; Cramer, P.: Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation. Genome Research 22 (7), pp. 1350 - 1359 (2012)

MPG.PuRe

188.

Journal Article

Koschubs, T.; Dengl, S.; Dürr, H.; Kaluza, K.; Georges, G.; Hartl, C.; Jennewein, S.; Lanzendörfer, M.; Auer, J.; Stern, A. et al.; Huang, K.‑.; Packman, K.; Gubler, U.; Kostrewa, D.; Ries, S.; Hansen, S.; Kohnert, U.; Cramer, P.; Mundigl, O.: Allosteric antibody inhibition of human hepsin protease. Biochemical Journal 442 (3), pp. 483 - 494 (2012)

MPG.PuRe

189.

Journal Article

Jennebach, S.; Herzog, F.; Aebersold, R.; Cramer, P.: Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage. Nucleic Acids Research 40 (12), pp. 5591 - 5601 (2012)

MPG.PuRe

190.

Journal Article

Wild, T.; Cramer, P.: Biogenesis of multisubunit RNA polymerases. Trends in Biochemical Sciences 37 (3), pp. 99 - 105 (2012)

MPG.PuRe

191.

Journal Article

Vannini, A.; Cramer, P.: Conservation between the RNA polymerase I, II, and III transcription initiation machineries. Molecular Cell 45 (4), pp. 439 - 446 (2012)

MPG.PuRe

192.

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