Publications

Journal Article (277)

1.
Journal Article
Farnung, L.; Ochmann, M.; Garg, G.; Vos, S.; Cramer, P.: Structure of a backtracked hexasomal intermediate of nucleosome transcription. Molecular Cell 82 (17), pp. 3126 - 3134.e7 (2022)
2.
Journal Article
Xiong, L.; Tolen, E. A.; Choi, J.; Velychko, S.; Caizzi, L.; Velychko, T.; Adachi, K.; MacCarthy, C. M.; Lidschreiber, M.; Cramer, P. et al.; Schöler, H. R.: Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. eLife 11, e71533 (2022)
3.
Journal Article
Dombrowski, M.; Engeholm, M.; Dienemann, C.; Dodonova, S. O.; Cramer, P.: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nature Structural and Molecular Biology 29 (5), pp. 493 - 501 (2022)
4.
Journal Article
Sahu, B.; Hartonen, T.; Pihlajamaa, P.; Wei, B.; Dave, K.; Zhu, F.; Kaasinen, E.; Lidschreiber, K.; Lidschreiber, M.; Daub, C. O. et al.; Cramer, P.; Kivioja, T.; Taipale, J.: Sequence determinants of human gene regulatory elements. Nature Genetics 54 (3), pp. 283 - 294 (2022)
5.
Journal Article
Downes, D. J.; Smith, A. L.; Karpinska, M. A.; Velychko, T.; Rue-Albrecht, K.; Sims, D.; Milne, T. A.; Davies, J. O. J.; Oudelaar, A. M.; Hughes, J. R.: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture. Nature Protocols 17 (2), pp. 445 - 475 (2022)
6.
Journal Article
Shao, R.; Kumar, B.; Lidschreiber, K.; Lidschreiber, M.; Cramer, P.; Elsässer, S. J.: Distinct transcription kinetics of pluripotent cell states. Molecular Systems Biology 18, e10407 (2022)
7.
Journal Article
Baar, T.; Dümcke, S.; Gressel, S.; Schwalb, B.; Dilthey, A.; Cramer, P.; Tresch, A.: RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. G3: Genes, Genomes, Genetics 12 (5), jkac054 (2022)
8.
Journal Article
Fianu, I.; Chen, Y.; Dienemann, C.; Dybkov, O.; Linden, A.; Urlaub, H.; Cramer, P.: Structural basis of Integrator-mediated transcription regulation. Science 374 (6569), pp. 883 - 887 (2021)
9.
Journal Article
Kokic, G.; Wagner, F. R.; Chernev, A.; Urlaub, H.; Cramer, P.: Structural basis of human transcription–DNA repair coupling. Nature 598 (7880), pp. 368 - 372 (2021)
10.
Journal Article
Aibara, S.; Dienemann, C.; Cramer, P.: Structure of an inactive RNA polymerase II dimer. Nucleic Acids Research 49 (18), pp. 10747 - 10755 (2021)
11.
Journal Article
García-Martínez, J.; Medina, D. A.; Bellvís, P.; Sun, M.; Cramer, P.; Chávez, S.; Pérez-Ortín, J. E.: The total mRNA concentration buffering system in yeast is global rather than gene-specific. RNA 27 (10), pp. 1281 - 1290 (2021)
12.
Journal Article
Güttler, T.; Aksu, M.; Dickmanns, A.; Stegmann, K. M.; Gregor, K.; Rees, R.; Taxer, W.; Rymarenko, O.; Schünemann, J.; Dienemann, C. et al.; Gunkel, P.; Mussil, B.; Krull, J.; Teichmann, U.; Groß, U.; Cordes, V.; Dobbelstein, M.; Görlich, D.: Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 40 (19), e107985 (2021)
13.
Journal Article
Bhatta, A.; Dienemann, C.; Cramer, P.; Hillen, H.: Structural basis of RNA processing by human mitochondrial RNase P. Nature Structural and Molecular Biology 28 (9), pp. 713 - 723 (2021)
14.
Journal Article
Cramer, P.: AlphaFold2 and the future of structural biology. Nature Structural and Molecular Biology 28 (9), pp. 704 - 705 (2021)
15.
Journal Article
Kabinger, F.; Stiller, C.; Schmitzova, J.; Dienemann, C.; Kokic, G.; Hillen, H. S.; Höbartner, C.; Cramer, P.: Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nature Structural and Molecular Biology 28 (9), pp. 740 - 746 (2021)
16.
Journal Article
Jochheim, F. A.; Tegunov, D.; Hillen, H. S.; Schmitzova, J.; Kokic, G.; Dienemann, C.; Cramer, P.: The structure of a dimeric form of SARS-CoV-2 polymerase. Communications Biology 4, 999 (2021)
17.
Journal Article
Zumer, K.; Maier, K. C.; Farnung, L.; Jaeger, M. G.; Rus, P.; Winter, G.; Cramer, P.: Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo. Molecular Cell 81 (15), pp. 3096 - 3109.e8 (2021)
18.
Journal Article
Wang, H.; Xiong, L.; Cramer, P.: Structures and implications of TBP–nucleosome complexes. Proceedings of the National Academy of Sciences of the USA 118 (30), e2108859118 (2021)
19.
Journal Article
Schilbach, S.; Aibara, S.; Dienemann, C.; Grabbe, F.; Cramer, P.: Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening. Cell 184 (15), pp. 4064 - 4072.e28 (2021)
20.
Journal Article
Chen, Y.; Vos, S. M.; Dienemann, C.; Ninov, M.; Urlaub, H.; Cramer, P.: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 81 (16), pp. 3386 - 3399.e10 (2021)
21.
Journal Article
Aibara, S.; Schilbach, S.; Cramer, P.: Structures of mammalian RNA polymerase II pre-initiation complexes. Nature 594 (7861), pp. 124 - 128 (2021)
22.
Journal Article
Rengachari, S.; Schilbach, S.; Aibara, S.; Dienemann, C.; Cramer, P.: Structure of the human Mediator-RNA polymerase II pre-initiation complex. Nature 594 (7861), pp. 129 - 133 (2021)
23.
Journal Article
Osman, S.; Mohammad, E.; Lidschreiber, M.; Stuetzer, A.; Bazsó, F. L.; Maier, K. C.; Urlaub, H.; Cramer, P.: The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 296, 100734 (2021)
24.
Journal Article
Oberbeckmann, E.; Niebauer, V.; Watanabe, S.; Farnung, L.; Moldt, M.; Schmid, A.; Cramer, P.; Peterson, C. L.; Eustermann, S.; Hopfner, K.-P. et al.; Korber, P.: Ruler elements in chromatin remodelers set nucleosome array spacing and phasing. Nature Communications 12, 3232 (2021)
25.
Journal Article
Fianu, I.; Dienemann, C.; Aibara, S.; Schilbach, S.; Cramer, P.: Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2. Communications Biology 4, 606 (2021)
26.
Journal Article
Caizzi, L.; Monteiro-Martins, S.; Schwalb, B.; Lysakovskaya, K.; Schmitzova, J.; Sawicka, A.; Chen, Y.; Lidschreiber, M.; Cramer, P.: Efficient RNA polymerase II pause release requires U2 snRNP function. Molecular Cell 81 (9), pp. 1920 - 1934.e9 (2021)
27.
Journal Article
Hillen, H. S.; Markov, D. A.; Wojtas, I. D.; Hofmann, K. B.; Lidschreiber, M.; Cowan, A. T.; Jones, J. L.; Temiakov, D.; Cramer, P.; Anikin, M.: The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs. Proceedings of the National Academy of Sciences of the USA 118 (15), e2009329118 (2021)
28.
Journal Article
Farnung, L.; Ochmann, M.; Engeholm, M.; Cramer, P.: Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nature Structural and Molecular Biology 28 (4), pp. 382 - 387 (2021)
29.
Journal Article
Choi, J.; Lysakovskaia, K.; Stik, G.; Demel, C.; Söding, J.; Tian, T. V.; Graf, T.; Cramer, P.: Evidence for additive and synergistic action of mammalian enhancers during cell fate determination. eLife 10, e65381 (2021)
30.
Journal Article
Rawat, P.; Böhning, M.; Hummel, B.; Aprile-Garcia, F.; Pandit, A. S.; Eisenhardt, N.; Khavaran, A.; Niskanen, E.; Vos, S. M.; Palvimo, J. J. et al.; Pichler, A.; Cramer, P.; Sawarkar, R.: Stress-induced nuclear condensation of NELF drives transcriptional downregulation. Molecular Cell 81 (5), pp. 1013 - 1026.e11 (2021)
31.
Journal Article
Endres, T.; Solvie, D.; Heidelberger, J. B.; Andriolett, V.; Baluapuri, A.; Ade, C. P.; Muhar, M.; Eilers, U.; Vos, S. M.; Cramer, P. et al.; Zuber, J.; Beli, P.; Popov, N.; Wolf, E.; Gallant, P.; Eilers, M.: Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Molecular Cell 81 (4), pp. 830 - 844.e13 (2021)
32.
Journal Article
Sawicka, A.; Villamil, G.; Lidschreiber, M.; Darzacq, X.; Dugast‐Darzacq, C.; Schwalb, B.; Cramer, P.: Transcription activation depends on the length of the RNA polymerase II C‐terminal domain. EMBO Journal 40 (9), e107015 (2021)
33.
Journal Article
Tegunov, D.; Xue, L.; Dienemann, C.; Cramer, P.; Mahamid, J.: Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells. Nature Methods 18 (2), pp. 186 - 193 (2021)
34.
Journal Article
Zhang, S.; Aibara, S.; Vos, S. M.; Agafonov, D.; Lührmann, R.; Cramer, P.: Structure of a transcribing RNA polymerase II–U1 snRNP complex. Science 371 (6526), pp. 305 - 309 (2021)
35.
Journal Article
Kokic, G.; Hillen, H. S.; Tegunov, D.; Dienemann, C.; Seitz, F.; Schmitzova, J.; Farnung, L.; Siewert, A.; Höbartner, C.; Cramer, P.: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nature Communications 12, 279 (2021)
36.
Journal Article
Kokic, G.; Hillen, H. S.; Tegunov, D.; Dienemann, C.; Seitz, F.; Schmitzova, J.; Farnung, L.; Siewert, A.; Höbartner, C.; Cramer, P.: Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nature Communications 12, 279 (2021)
37.
Journal Article
Cramer, P.; Kokic, G.; Dienemann, C.; Höbartner, C.; Hillen, H. S.: Coronavirus-Replikation: Mechanismus und Inhibition durch Remdesivir. Biospektrum 27 (1), pp. 49 - 53 (2021)
38.
Journal Article
Kim, K.-P.; Choi, J.; Yoon, J.; Bruder, J. M.; Shin, B.; Kim, J.; Arauzo-Bravo, M. J.; Han, D.; Wu, G.; Han, D. W. et al.; Kim, J.; Cramer, P.; Schöler, H. R.: Permissive epigenomes endow reprogramming competence to transcriptional regulators. Nature Chemical Biology 17 (1), pp. 47 - 56 (2021)
39.
Journal Article
Lidschreiber, K.; Jung, L. A.; von der Emd, H.; von der Emde, H.; Dave, K.; Taipale, J.; Cramer, P.; Lidschreiber, M.: Transcriptionally active enhancers in human cancer cells. Molecular Systems Biology 17 (1), e9873 (2021)
40.
Journal Article
Lykke-Andersen, S.; Zumer, K.; Molska, E. Š.; Rouvière, J. O.; Wu, G.; Demel, C.; Schwalb, B.; Schmid, M.; Cramer, P.; Jensen, T. H.: Integrator is a genome-wide attenuator of non-productive transcription. Molecular Cell, in Press (2020)
41.
Journal Article
Bonekamp, N. A.; Peter, B.; Hillen, H. S.; Felser, A.; Bergbrede, T.; Choidas, A.; Horn, M.; Unger, A.; Di Lucrezia, R.; Atanassov, I. et al.; Li, X.; Koch, U.; Menninger, S.; Boros, J.; Habenberger, P.; Giavalisco, P.; Cramer, P.; Denzel, M. S.; Nussbaumer, P.; Klebl, B.; Falkenberg, M.; Gustafsson, C. M.; Larsson, N.-G.: Small-molecule inhibitors of human mitochondrial DNA transcription. Nature 588 (7839), pp. 712 - 716 (2020)
42.
Journal Article
Osman, S.; Cramer, P.: Structural biology of RNA polymerase II transcription: 20 years on. Annual Review of Cell and Developmental Biology 36, pp. 1 - 34 (2020)
43.
Journal Article
Maier, K. C.; Gressel, S.; Cramer, P.; Schwalb, B.: Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms. Genome Research 30 (9), pp. 1332 - 1344 (2020)
44.
Journal Article
Cramer, P.: Rosalind Franklin and the advent of molecular biology. Cell 182 (4), pp. 787 - 789 (2020)
45.
Journal Article
Tellier, M.; Zaborowska, J.; Caizzi, L.; Mohammad, E.; Velychko, T.; Schwalb, B.; Ferrer-Vicens, I.; Blears, D.; Nojima, T.; Cramer, P. et al.; Murphy, S.: CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. Nucleic Acids Research 48 (14), pp. 7712 - 7727 (2020)
46.
Journal Article
Hillen, H.; Kokic, G.; Farnung, L.; Dienemann, C.; Tegunov, D.; Cramer, P.: Structure of replicating SARS-CoV-2 polymerase. Nature 584 (7819), pp. 154 - 156 (2020)
47.
Journal Article
O’Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Blötz, C.; Singh, N.; Hagen, W. J. H.; Cramer, P. et al.; Stülke, J.; Mahamid, J.; Rappsilber, J.: In-cell architecture of an actively transcribing-translating expressome. Science 369 (6503), pp. 554 - 557 (2020)
48.
Journal Article
Jaeger, M. G.; Schwalb, B.; Mackowiak, S. D.; Velychko, T.; Hanzl, A.; Imrichova, H.; Brand, M.; Agerer, B.; Chorn, S.; Nabet, B. et al.; Ferguson, F. M.; Müller, A. C.; Bergthaler, A.; Gray, N. S.; Bradner, J. E.; Bock, C.; Hnisz, D.; Cramer, P.; Winter, G. E.: Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics 52 (7), pp. 719 - 727 (2020)
49.
Journal Article
Stik, G.; Vidal, E.; Barrero, M.; Cuartero, S.; Vila-Casadesús, M.; Mendieta-Esteban, J.; Tian, T. V.; Choi, J.; Berenguer, C.; Abad, A. et al.; Borsari, B.; le Dily, F.; Cramer, P.; Marti-Renom, M. A.; Stadhouders, R.; Graf, T.: CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response. Nature Genetics 52 (7), pp. 655 - 661 (2020)
50.
Journal Article
Vos, S. M.; Farnung, L.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 27 (7), pp. 668 - 677 (2020)
51.
Journal Article
Farnung, L.; Ochmann, M.; Cramer, P.: Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. eLife 9, e56178 (2020)
52.
Journal Article
Parfentev, I.; Schilbach, S.; Cramer, P.; Urlaub, H.: An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 220, 103754 (2020)
53.
Journal Article
Dodonova, S. O.; Zhu, F.; Dienemann, C.; Taipale, J.; Cramer, P.: Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 580 (7805), pp. 669 - 672 (2020)
54.
Journal Article
Wagner, F. R; Dienemann, C.; Wang, H.; Stützer, A.; Tegunov, D.; Urlaub, H.; Cramer, P.: Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 579 (7799), pp. 448 - 451 (2020)
55.
Journal Article
Cramer, P.: 500 years after the first circumnavigation of the world: The efforts, rewards and drawbacks of exploration. FEBS Letters 594 (2), pp. 207 - 208 (2020)
56.
Journal Article
Lefranc, J.; Schulze, V. K.; Hillig, R. C.; Briem, H.; Prinz, F.; Mengel, A.; Heinrich, T.; Balint, J.; Rengachari, S.; Irlbacher, H. et al.; Stockigt, D.; Bömer, U.; Bader, B.; Gradl, S. N.; Nising, C. F.; von Nussbaum, F.; Mumberg, D.; Panne, D.; Wengner, A. M.: Discovery of BAY-985, a highly selective TBK1/IKK epsilon inhibitor. Journal of Medicinal Chemistry 63 (2), pp. 601 - 612 (2020)
57.
Journal Article
Söding, J.; Zwicker, D.; Sohrabi-Jahromi, S.; Boehning, M.; Kirschbaum, J.: Mechanisms for active regulation of biomolecular condensates. Trends in Cell Biology 30 (1), pp. 4 - 14 (2020)
58.
Journal Article
Wang, H.; Dienemann, C.; Stützer, A.; Urlaub, H.; Cheung, A. C. M.; Cramer, P.: Structure of the transcription coactivator SAGA. Nature 577, pp. 717 - 720 (2020)
59.
Journal Article
Wang, H.; Farnung, L.; Dienemann, C.; Cramer, P.: Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nature Structural and Molecular Biology 27 (1), pp. 8 - 13 (2020)
60.
Journal Article
Grimm, C.; Hillen, H. S.; Bedenk, K.; Bartuli, J.; Neyer, S.; Zhang, Q.; Hüttenhofer, A.; Erlacher, M.; Dienemann, C.; Schlosser, A. et al.; Urlaub, H.; Böttcher, B.; Szalay, A. A.; Cramer, P.; Fischer, U.: Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 179 (7), pp. 1537 - 1550 (2019)
61.
Journal Article
Hillen, H. S.; Bartuli, J.; Grimm, C.; Dienemann, C.; Bedenk, K.; Szalay, A. A.; Fischer, U.; Cramer, P.: Structural basis of poxvirus transcription: Transcribing and capping vaccinia complexes. Cell 179 (7), pp. 1525 - 1536 (2019)
62.
Journal Article
Tegunov, D.; Cramer, P.: Real-time cryo-electron microscopy data preprocessing with Warp. Nature Methods 16, pp. 1146 - 1152 (2019)
63.
Journal Article
Chang, C. T.; Muthukumar, S.; Weber, R.; Levdansky, Y.; Chen, Y.; Bhandari, D.; Igreja, C.; Wohlbold, L.; Valkov, E.; Izaurralde, E.: A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5 '-3 ' messenger RNA decay. Nucleic Acids Research 47 (17), pp. 9282 - 9295 (2019)
64.
Journal Article
Zhang, S.; Tischer, T.; Barford, D.: Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C. Nature Communications 10, 3863 (2019)
65.
Journal Article
Mahamid, J.; Tegunov, D.; Maiser, A.; Arnold, J.; Leonhardt, H.; Plitzko, J. M.; Baumeister, W.: Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association. Proceedings of the National Academy of Sciences of the United States of America 116 (34), pp. 16866 - 16871 (2019)
66.
Journal Article
Gressel, S.; Schwalb, B.; Cramer, P.: The pause-initiation limit restricts transcription activation in human cells. Nature Communicationsvolume 10 (1), 3603 (2019)
67.
Journal Article
Hendriks, G. J.; Jung, L. A.; Larsson, A. J. M.; Lidschreiber, M.; Forsman, O. A.; Lidschreiber, K.; Cramer, P.; Sandberg, R.: NASC-seq monitors RNA synthesis in single cells. Nature Communications 10 (1), 3138 (2019)
68.
Journal Article
Chen, Y.; Cramer, P.: Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. Journal of Biological Chemistry 294, pp. 10663 - 10673 (2019)
69.
Journal Article
Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10, 2885 (2019)
70.
Journal Article
Sohrabi-Jahromi, S.; Hofmann, K. B.; Boltendahl, A.; Roth, C.; Gressel, S.; Baejen, C.; Söding, J.; Cramer, P.: Transcriptome maps of general eukaryotic RNA degradation factors. eLife 8, e47040 (2019)
71.
Journal Article
Baluapuri, A.; Hofstetter, J.; Dudvarski Stankovic, N.; Endres, T.; Bhandare, P.; Vos, S. M.; Adhikari, B.; Schwarz, J. D.; Narain, A.; Vogt, M. et al.; Wang, S. Y.; Düster, R.; Jung, L. A.; Vanselow, J. T.; Wiegering, A.; Geyer, M.; Maric, H. M.; Gallant, P.; Walz, S.; Schlosser, A.; Cramer, P.; Eilers, M.; Wolf, E.: MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Molecular Cell 74 (4), pp. 674 - 687 (2019)
72.
Journal Article
Jones, J. L.; Hofmann, K. B.; Cowan, A. T.; Temiakov, D.; Cramer, P.; Anikin, M.: Yeast mitochondrial protein Pet111p binds directly to two distinct targets in COX2 mRNA, suggesting a mechanism of translational activation. Journal of Biological Chemistry 294 (18), pp. 7528 - 7536 (2019)
73.
Journal Article
Dodonova, S. O.; Prinz, S.; Bilanchone, V.; Sandmeyer, S.; Briggs, J. A. G.: Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 116 (20), pp. 10048 - 10057 (2019)
74.
Journal Article
Wachutka, L.; Caizzi, L.; Gagneur, J.; Cramer, P.: Global donor and acceptor splicing site kinetics in human cells. eLife 8, e45056 (2019)
75.
Journal Article
Villamizar, G. A. C.; Nacke, H.; Böhning, M.; Herz, K.; Daniel, R.: Functional metagenomics reveals an overlooked diversity and novel features of soil-derived bacterial phosphatases and phytases. mBio 10 (1), e01966-18 (2019)
76.
Journal Article
Zylicz, J. J.; Bousard, A.; Zumer, K.; Dossin, F.; Mohammad, E.; da Rocha, S. T.; Schwalb, B.; Syx, L.; Dingli, F.; Loew, D. et al.; Cramer, P.; Heard, E.: The implication of early chromatin changes in X chromosome inactivation. Cell 176 (1-2), pp. 182 - 197 (2019)
77.
Journal Article
Dienemann, C.; Schwalb, B.; Schilbach, S.; Cramer, P.: Promoter distortion and opening in the RNA polymerase II cleft. Molecular Cell 73 (1), pp. 97 - 106 (2019)
78.
Journal Article
Cramer, P.: Organization and regulation of gene transcription. Nature 573, pp. 45 - 54 (2019)
79.
Journal Article
Cramer, P.: Eukaryotic transcription turns 50. Cell 179 (4), pp. 808 - 812 (2019)
80.
Journal Article
Farnung, L.; Vos, S. M.; Cramer, P.: Structure of transcribing RNA polymerase II-nucleosome complex. Nature Communications 9, 5432 (2018)
81.
Journal Article
Lidschreiber, M.; Easter, A. D.; Battaglia, S.; Rodríguez-Molina, J. B.; Casañal, A.; Carminati, M.; Baejen, C.; Grzechnik, P.; Maier, K. C.; Cramer, P. et al.; Passmore, L. A.: The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 46 (21), pp. 11528 - 11538 (2018)
82.
Journal Article
Ortega, E.; Rengachari, S.; Ibrahim, Z.; Hoghoughi, N.; Gaucher, J.; Holehouse, A. S.; Khochbin, S.; Panne, D.: Transcription factor dimerization activates the p300 acetyltransferase. Nature 562 (7728), pp. 538 - 544 (2018)
83.
Journal Article
Zhu, F.; Farnung, L.; Kaasinen, E.; Sahu, B.; Yin, Y.; Wei, B.; Dodonova, S. O.; Nitta, K. R.; Morgunova, E.; Taipale, M. et al.; Cramer, P.; Taipale, J.: The interaction landscape between transcription factors and the nucleosome. Nature 562 (7725), pp. 76 - 81 (2018)
84.
Journal Article
Böhning, M.; Dugast-Darzacq, C.; Rankovic, M.; Hansen, A. S.; Yu, T.; Marie-Nelly, H.; McSwiggen, D. T.; Kokic, G.; Dailey, G. M.; Cramer, P. et al.; Darzacq, X.; Zweckstetter, M.: RNA polymerase II clustering through carboxy-terminal domain phase separation. Nature Structural and Molecular Biology 25 (9), pp. 833 - 840 (2018)
85.
Journal Article
Hillen, H. S.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription. Nature Structural and Molecular Biology 25 (9), pp. 754 - 765 (2018)
86.
Journal Article
Vos, S. M.; Farnung, L.; Böhning, M.; Wigge, C.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), pp. 607 - 612 (2018)
87.
Journal Article
Vos, S. M.; Farnung, L.; Urlaub, H.; Cramer, P.: Structure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), pp. 601 - 606 (2018)
88.
Journal Article
La Manno, G.; Soldatov, R.; Zeisel, A.; Braun, E.; Hochgerner, H.; Petukhov, V.; Lidschreiber, K.; Kastriti, M. E.; Lönnerberg, P.; Furlan, A. et al.; Fan, J.; Borm, L. E.; Liu, Z.; van Bruggen, D.; Guo, J.; He, X.; Barker, R.; Sundström, E.; Castelo-Branco, G.; Cramer, P.; Adameyko, I.; Linnarsson, S.; Kharchenko, P. V.: RNA velocity of single cells. Nature 560 (7719), pp. 494 - 498 (2018)
89.
Journal Article
Liu, X.; Farnung, L.; Wigge, C.; Cramer, P.: Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by α-amanitin. Journal of Biological Chemistry 293 (19), pp. 7189 - 7194 (2018)
90.
Journal Article
Engel, C.; Neyer, S.; Cramer, P.: Distinct mechanisms of transcription initiation by RNA polymerases I and II. Annual Review of Biophysics 47, pp. 425 - 446 (2018)
91.
Journal Article
Hantsche, M.; Cramer, P.: Conserved RNA polymerase II initiation complex structure. Current Opinion in Structural Biology 47, pp. 17 - 22 (2017)
92.
Journal Article
Bykov, Y. S.; Schaffer, M.; Dodonova, S. O.; Albert, S.; Plitzko, J. M.; Baumeister, W.; Engel, B. D.; Briggs, J. A. G.: The structure of the COPI coat determined within the cell. eLife 6, e32493 (2017)
93.
Journal Article
Hillen, H. S.; Morozov, Y. I.; Sarfallah, A.; Temiakov, D.; Cramer, P.: Structural basis of mitochondrial transcription initiation. Cell 171 (5), pp. 1072 - 1081 (2017)
94.
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