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RNA polymerase III subunit architecture and implications for open promoter complex formation. Proceedings of the National Academy of Sciences of the USA 202.
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40 (18), pp. 8883 - 8892 (2012)
One Hand Clapping: detection of condition-specific transcription factor interactions from genome-wide gene activity data. Nucleic Acids Research 203.
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336 (6089), pp. 1723 - 1725 (2012)
CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II. Science 204.
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149 (7), pp. 1431 - 1437 (2012)
A movie of RNA polymerase II transcription. Cell 205.
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8 (6), e1002568 (2012)
MC EMiNEM maps the interaction landscape of the Mediator. PLoS Computational Biology 206.
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46 (2), pp. 136 - 146 (2012)
Dynamic architecture of a minimal RNA polymerase II open promoter complex. Molecular Cell 207.
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46 (1), pp. 18 - 29 (2012)
Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Molecular Cell 208.
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22 (7), pp. 1350 - 1359 (2012)
Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation. Genome Research 209.
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442 (3), pp. 483 - 494 (2012)
Allosteric antibody inhibition of human hepsin protease. Biochemical Journal 210.
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40 (12), pp. 5591 - 5601 (2012)
Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage. Nucleic Acids Research 211.
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37 (3), pp. 99 - 105 (2012)
Biogenesis of multisubunit RNA polymerases. Trends in Biochemical Sciences 212.
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45 (4), pp. 439 - 446 (2012)
Conservation between the RNA polymerase I, II, and III transcription initiation machineries. Molecular Cell 213.
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24 (3), pp. 305 - 313 (2012)
A structural perspective on Mediator function. Current Opinion in Cell Biology 214.
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32 (7), pp. 1321 - 1331 (2012)
The Spt5 C-terminal region recruits yeast 3= RNA cleavage factor I. Molecular and Cellular Biology 215.
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28 (6), pp. 884 - 885 (2012)
Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA). Bioinformatics 216.
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30 (23), pp. 4755 - 4763 (2011)
Structural basis of initial RNA polymerase II transcription. EMBO Journal 217.
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6 (11), e27595 (2011)
A conserved GA element in TATA-less RNA polymerase II promoters. PLoS One 218.
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Structure of human mitochondrial RNA polymerase. Nature 219.
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25 (19), pp. 2093 - 2105 (2011)
Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes and Development 220.
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50 (25), pp. 5749 - 5752 (2011)
A conformational switch underlies ClpP protease function. Angewandte Chemie International Edition 221.
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42 (2), pp. 261 - 266 (2011)
Iwr1 directs RNA polymerase II nuclear import. Molecular cell 222.
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9 (4), e1000611 (2011)
A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biology 223.
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39 (14), pp. 6291 - 6304 (2011)
Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization. Nucleic Acids Research 224.
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18 (4), pp. 404 - 409 (2011)
Structure and VP16 binding of the Mediator Med25 activator interaction domain. Nature Structural and Molecular Biology 225.
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286 (21), pp. 18701 - 18707 (2011)
Evolution of two modes of intrinsic RNA polymerase transcript cleavage. Journal of Biological Chemistry 226.
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Structural basis of RNA polymerase II backtracking, arrest and reactivation. Nature 227.
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30 (7), pp. 1302 - 1310 (2011)
Architecture of the RNA polymerase–Spt4/5 complex and basis of universal transcription processivity. EMBO Journal 228.
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Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast. Molecular Systems Biology 229.
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285 (53), pp. 41665 - 41674 (2010)
The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress. Journal of Biological Chemistry 230.
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285 (53), pp. 41597 - 41603 (2010)
A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain (CTD). Journal of Biological Chemistry 231.
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38 (19), pp. 6707 - 6718 (2010)
The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis. Nucleic Acids Research 232.
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143 (1), pp. 59 - 70 (2010)
Molecular basis of RNA polymerase III transcription repression by Maf1. Cell 233.
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17 (10), pp. 1272 - 1278 (2010)
Uniform transitions of the general RNA polymerase II transcription complex. Nature Structural and Molecular Biology 234.
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39 (4), pp. 583 - 594 (2010)
RNA polymerase I contains a TFIIF-related DNA-binding subcomplex. Molecular Cell 235.
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391 (7), pp. 731 - 735 (2010)
Towards molecular systems biology of gene transcription and regulation. Biological Chemistry 236.
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38 (12), pp. 4040 - 4051 (2010)
Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif. Nucleic Acids Research 237.
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29 (4), pp. 717 - 726 (2010)
Architecture of the RNA polymerase II–TFIIF complex revealed by cross‐linking and mass spectrometry. EMBO Journal 238.
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38 (10), pp. 3186 - 3195 (2010)
Preparation and topology of the Mediator middle module. Nucleic Acids Research 239.
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16 (1), pp. 24 - 27 (2010)
10 Jahre RNA-Polymerase-Struktur – von Transkription zu Genregulation. BIOspektrum 240.
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462 (7271), pp. 323 - 330 (2009)
RNA polymerase II–TFIIB structure and mechanism of transcription initiation. Nature 241.
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19 (6), pp. 732 - 739 (2009)
RNA polymerase fidelity and transcriptional proofreading. Current Opinion in Structural Biology 242.
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284 (46), pp. 31658 - 31663 (2009)
Molecular basis of transcriptional mutagenesis at 8-Oxoguanine. Journal of Biological Chemistry 243.
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284 (32), pp. 21270 - 21279 (2009)
Torpedo nuclease Rat1 is insufficient to terminate RNA polymerase II in vitro. The Journal of Biological Chemistry 244.
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37 (17), pp. 5803 - 5809 (2009)
Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex. Nucleic Acids Research 245.
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34 (6), pp. 710 - 721 (2009)
Structural basis of transcription: Mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Molecular Cell 246.
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19 (3), pp. 294 - 299 (2009)
A movie of the RNA polymerase nucleotide addition cycle. Current Opinion in Structural Biology 247.
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389 (1), pp. 211 - 225 (2009)
Structure and in vivo requirement of the yeast Spt6 SH2 domain. Journal of Molecular Biology 248.
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65 (2), pp. 112 - 120 (2009)
Structure–function studies of the RNA polymerase II elongation complex. Acta Crystallographica Section D: Biological Crystallography 249.
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71 (4), pp. 989 - 1002 (2009)
The archaeal RNA polymerase subunit P and the eukaryotic polymerase subunit Rpb12 are interchangeable in vivo and in vitro. Molecular Microbiology 250.
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28 (1), pp. 69 - 80 (2009)
Identification, structure, and functional requirement of the Mediator submodule Med7N/31. The EMBO Journal