Publikationen

Dereddi, R. R.; Djannatian, M.; Fiore, F.; Kalita, D.; Verkest, C.; Torres, F. B.; Möbius, W.; Khodaie, B.; Ruhwedel, T.; Alhalaseh, K. et al.; Schifferer, M.; Wirth, A.; Hill, A.; Ottenheijm, R.; Patrizi, A.; Kann, O.; Lechner, S. G.; Freichel, M.; Agarwal, A.: Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry. Neuron (2026)

Choezom, D.; Notter, S.; Griebel, T.; Ferreira, N.; Gruetz, J.; Kulkarni, A.; Schröter, M.; Lukinavičius, G.; Möbius, W.; Conradi, L.-C. et al.; Feldmann, C.; Alves, F.: Macropinocytic Uptake and pH-Responsive Endolysosomal Processing Drive Sustained Chemotherapeutic Efficacy of High-Load Core@Shell Nanocarriers in Colorectal Cancer. Small Science (2025)

Schmitz, M.; Thüne, K.; Fischer, A.; Hermann, P.; Cramm, M.; Kadel, L. S.; Möbius, W.; Matschke, J.; Saleem, T.; Younas, N. et al.; Zafar, S.; Altmeppen, H.; Glatzel, M.; Zerr, I.: Evidence for different seeding activities of misfolded tau in classical and rapidly progressive Alzheimer's disease. Brain Pathology (2025)

Ries, C.; Stark, T.; Boulat, B.; Ruhwedel, T.; Delling, J. P.; Infante, A. M.; von Poblotzki, J. T.; Ulivi, A.; von Mucke-Heim, I.-A.; Chang, S. et al.; Sakimura, K.; Itoi, K.; Nestvogel, D. B.; Attardo, A.; Czisch, M.; Nave, K.-A.; Möbius, W.; Dimou, L.; Deussing, J. M.: Neuropeptide CRH prevents premature differentiation of OPCs following CNS injury and in early postnatal development. Cell Reports 44 (11), 116474 (2025)

Kapoor, R.; Kim, H.; Garlick, E.; Lima, M. A. d. R. B. F.; Esch, K.; Ruhwedel, T.; Möbius, W.; Wolf, F.; Moser, T.: Charting the nanotopography of inner hair cell synapses using MINFLUX nanoscopy. Science Advances 11 (45), eady4344 (2025)

Fernandez Flores, L. C.; Younas, N.; Goebel, S.; Dittmar, K.; Saleem, T.; Younas, A.; Budde, H.; Legler, T. J.; Möbius, W.; Hermann, P. et al.; Schmitz, M.; Zerr, I.: Multiple Antibody-Coated Gold Nanoparticle-Based ExoAssay for Rapid Isolation of CNS-Specific Exosomes From Blood. Journal of Neurochemistry 169 (10), e70263 (2025)

Ye, L.; Daguano Gastaldi, V.; Curto, Y.; Wildenburg, A.-F.; Yu, X.; Hindermann, M.; Eggert, S.; Ronnenberg, A.; Wang, Q.; Butt, U. J. et al.; Kawaguchi, R.; Geschwind, D.; Möbius, W.; Boretius, S.; Singh, M.; Nave, K. A.; Ehrenreich, H.: Transcriptional dynamics of the oligodendrocyte lineage and its regulation by the brain erythropoietin system. Nature Communications 16, 8291 (2025)

Jansari, S.; Blandau, A.; Prokakis, E.; Grimm, D.; Naßl, A. M.; Küffer, S.; Möbius, W.; Dullin, C.; Ramos Gomes, F.; Schüürhuis, L. et al.; Fritsche, L.; Schridde, L.; Plessner, M.; Bast, C. A.; Gayer, F. A.; Thoms, S.; Gallwas, J.; Wegwitz, F.: RNF20/RNF40 supports the aggressive behavior in cervical cancer by regulating a peroxisome-based anti-ferroptotic mechanism. Cell Communication and Signaling 23, 304 (2025)

Schneeberger, S.; Kim, S. J.; Geesdorf, M. N.; Friebel, E.; Eede, P.; Jendrach, M.; Boltengagen, A.; Braeuning, C.; Ruhwedel, T.; Hülsmeier, A. J. et al.; Gimber, N.; Foerster, M.; Obst, J.; Andreadou, M.; Mundt, S.; Schmoranzer, J.; Prokop, S.; Kessler, W.; Kuhlmann, T.; Möbius, W.; Nave, K.-A.; Hornemann, T.; Becher, B.; Edgar, J. M.; Karaiskos, N.; Kocks, C.; Rajewsky, N.; Heppner, F. L.: Interleukin-12 signaling drives Alzheimer’s disease pathology through disrupting neuronal and oligodendrocyte homeostasis. Nature aging 5, S. 622 - 641 (2025)

Garg, V.; Möbius, W.; Heinrich, R.; Ruhwedel, T.; Perera, R. P.; Scholz, P.; Ischebeck, T.; Salinas, G.; Dullin, C.; Göpfert, M. C. et al.; Engelmann, J.; Dosch, R.; Geurten, B. R. H.: Patient-specific mutation of a contact site protein Tomm70 causes neurodegeneration in a zebrafish model. Disease Models & Mechanisms 18 (4), dmm052029 (2025)

Lohrberg, M.; Mortensen, L. S.; Thomas, C.; Fries, F.; van der Meer, F.; Götz, A.; Landt, C.; Rhee, H. J.; Rhee, J. S.; Gómez-Varela, D. et al.; Schmidt, M.; Möbius, W.; Ruhwedel, T.; Pardo, L. A.; Remling, L.; Kramann, N.; Wrzos, C.; Bahn, E.; Stadelmann, C.; Barrantes-Freer, A.: Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination. Journal of Neuroinflammation 22, 47 (2025)

Garg, V.; André, S.; Heyer, L.; Kracht, G.; Ruhwedel, T.; Scholz, P.; Ischebeck, T.; Werner, H. B.; Dullin, C.; Engelmann, J. et al.; Möbius, W.; Göpfert, M. C.; Dosch, R.; Geurten, B. R. H.: Axon demyelination and degeneration in a zebrafish spastizin model of hereditary spastic paraplegia. Open Biology 14 (11), 240100 (2024)

Notter, S.; Choezom, D.; Griebel, T.; Ramos Gomes, F.; Möbius, W.; De Oliveira, T.; Conradi, L.-C.; Alves, F.; Feldmann, C.: High-Load Core@Shell Nanocarriers with Irinotecan and 5-Fluorouracil for Combination Chemotherapy in Colorectal Cancer. Small Science 4 (11), 2400196 (2024)

Asadollahi, E.; Trevisiol, A.; Saab, A. S.; Looser, Z. J.; Dibaj, P.; Ebrahimi, R.; Kusch, K.; Ruhwedel, T.; Möbius, W.; Jahn, O. et al.; Lee, J. Y.; Don, A. S.; Khalil, M.-A.; Hiller, K.; Baes, M.; Weber, B.; Abel, E. D.; Ballabio, A.; Popko, B.; Kassmann, C. M.; Ehrenreich, H.; Hirrlinger, J.; Nave, K.-A.: Oligodendroglial fatty acid metabolism as a central nervous system energy reserve. Nature Neuroscience 27, S. 1934 - 1944 (2024)

Gargareta, V.-I.; Berghoff, S. A.; Krauter, D.; Hümmert, S.; Marshall‐Phelps, K. L. H.; Möbius, W.; Nave, K.-A.; Fledrich, R.; Werner, H. B.; Eichel-Vogel, M. A.: Myelinated peripheral axons are more vulnerable to mechanical trauma in a model of enlarged axonal diameters. Glia 72 (9), S. 1572 - 1589 (2024)

Aich, A.; Boshnakovska, A.; Witte, S.; Gall, T.; Unthan-Fechner, K.; Yousefi, R.; Chowdhury, A.; Dahal, D.; Methi, A.; Kaufmann, S. et al.; Silbern, I.; Prochazka, J.; Nichtova, Z.; Palkova, M.; Raishbrook, M.; Koubkova, G.; Sedlacek, R.; Tröder, S.E.; Zevnik, B.; Riedel, D.; Michanski, S.; Möbius, W.; Ströbel, P.; Lüchtenborg, C.; Giavalisco, P.; Urlaub, H.; Fischer, A.; Brügger, B.; Jakobs, S.; Rehling, P.: Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Nature Communications 15, 6914 (2024)

Sasmita, A. O.; Depp, C.; Nazarenko, T.; Sun, T.; Siems, S. B.; Ong, E. C.; Nkeh, Y. B.; Böhler, C.; Yu, X.; Bues, B. et al.; Evangelista, L.; Mao, S.; Morgado, B.; Wu, Z.; Ruhwedel, T.; Subramanian, S.; Börensen, F.; Overhoff, K.; Spieth, L.; Berghoff, S. A.; Sadleir, K. R.; Vassar, R.; Eggert, S.; Goebbels, S.; Saito, T.; Saido, T.; Saher, G.; Möbius, W.; Castelo-Branco, G.; Klafki, H.-W.; Wirths, O.; Wiltfang, J.; Jäkel, S.; Yan, R.; Nave, K.-A.: Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice. Nature Neuroscience 27, S. 1668 - 1674 (2024)

Foerster, S.; Floriddia, E. M.; van Bruggen, D.; Kukanja, P.; Hervé, B.; Cheng, S.; Kim, E.; Phillips, B. U.; Heath, C. J.; Tripathi, R. B. et al.; Call, C.; Bartels, T.; Ridley, K.; Neumann, B.; López-Cruz, L.; Crawford, A. H.; Lynch, C. J.; Serrano, M.; Saksida, L.; Rowitch, D. H.; Möbius, W.; Nave, K.-A.; Rasband, M. N.; Bergles, D. E.; Kessaris, N.; Richardson, W. D.; Bussey, T. J.; Zhao, C.; Castelo-Branco, G.; Franklin, R. J. M.: Developmental origin of oligodendrocytes determines their function in the adult brain. Nature Neuroscience 27, S. 1545 - 1554 (2024)

Chatterjee, M.; Özdemir, S.; Fritz, C.; Möbius, W.; Kleineidam, L.; Mandelkow, E.; Biernat, J.; Doğdu, C.; Peters, O.; Cosma, N.C. et al.; Wang, X.; Schneider, L.-S.; Priller, J.; Spruth, E.; Kühn, A.A.; Krause, P.; Klockgether, T.; Vogt, I.R.; Kimmich, O.; Spottke, A.; Hoffmann, D.C.; Fliessbach, K.; Miklitz, C.; McCormick, C.; Weydt, P.; Falkenburger, B.; Brandt, M.; Guenther, R.; Dinter, E.; Wiltfang, J.; Hansen, N.; Bähr, M.; Zerr, I.; Flöel, A.; Nestor, P.J.; Düzel, E.; Glanz, W.; Incesoy, E.; Bürger, K.; Janowitz, D.; Perneczky, R.; Rauchmann, B.S.; Hopfner, F.; Wagemann, O.; Levin, J.; Teipel, S.; Kilimann, I.; Goerss, D.; Prudlo, J.; Gasser, T.; Brockmann, K.; Mengel, D.; Zimmermann, M.; Synofzik, M.; Wilke, C.; Selma-González, J.; Turon-Sans, J.; Santos-Santos, M.A.; Alcolea, D.; Rubio-Guerra, S.; Fortea, J.; Carbayo, Á.; Lleó, A.; Rojas-García, R.; Illán-Gala, I.; Wagner, M.; Frommann, I.; Roeske, S.; Bertram, L.; Heneka, M.T.; Brosseron, F.; Ramirez, A.; Schmid, M.; Beschorner, R.; Halle, A.; Herms, J.; Neumann, M.; Barthélemy, N.R.; Bateman, R.J.; Rizzu, P.; Heutink, P.; Dols-Icardo, O.; Höglinger, G.; Hermann, A.; Schneider, A.: Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS. Nature Medicine 30 (6), S. 1771 - 1783 (2024)

Späte, E.; Zhou, B.; Sun, T.; Kusch, K.; Asadollahi, E.; Siems, S. B.; Depp, C.; Werner, H. B.; Saher, G.; Hirrlinger, J. et al.; Möbius, W.; Nave, K.-A.; Göbbels, S.: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons. Glia 72 (8), S. 1374 - 1391 (2024)