Publications
Journal Article (93)
1.
Journal Article
125 (3), e30523 (2024)
In silico analysis of alpha‐synuclein protein variants and posttranslational modifications related to Parkinson's disease. Journal of Cellular Biochemistry 2.
Journal Article
121 (2), e2309700120 (2024)
Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid. PNAS 3.
Journal Article
13 (1), e6900 (2024)
Uncovering potential diagnostic and pathophysiological roles of α-synuclein and DJ-1 in melanoma. Cancer Medicine 4.
Journal Article
147 (1), pp. 81 - 90 (2024)
Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies. Brain 5.
Journal Article
147 (1), 40 (2024)
Regional AT-8 reactive tau species correlate with intracellular Aβ levels in cases of low AD neuropathologic change. Acta Neuropathologica 6.
Journal Article
1869 (8), 166835 (2023)
Glycation modulates superoxide dismutase 1 aggregation and toxicity in models of sporadic amyotrophic lateral sclerosis. Biochimica et Biophysica Acta-Molecular Basis of Disease 7.
Journal Article
PrP meets alpha-synuclein: Molecular mechanisms and implications for disease. Journal of Neurochemistry (2023)
8.
Journal Article
146, pp. 369 - 385 (2023)
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy. Acta Neuropathologica 9.
Journal Article
166 (5), pp. 862 - 874 (2023)
Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease. Journal of Neurochemistry 10.
Journal Article
38 (9), pp. 1585 - 1597 (2023)
Extracellular Vesicles for the Diagnosis of Parkinson's Disease: Systematic Review and Meta-Analysis. Movement Disorders 11.
Journal Article
24 (17), 13435 (2023)
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease. International Journal of Molecular Sciences 12.
Journal Article
29 (1), 111 (2023)
The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis. Molecular Medicine 13.
Journal Article
39 (4-6), pp. 321 - 335 (2023)
Uncovering the Molecular Link Between Lead Toxicity and Parkinson's Disease. Antioxidants & redox signaling 14.
Journal Article
19 (8), pp. 453 - 454 (2023)
AI and protein structure and function in neurological disease: relevance to disease management. Nature Reviews Neurology 15.
Journal Article
38 (7), pp. 1127 - 1142 (2023)
Defining the riddle in order to solve it: There is more than one "Parkinson's Disease". Movement Disorders 16.
Journal Article
Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease. Journal of Neurochemistry, in press (2023)
17.
Journal Article
123 (14), pp. 9094 - 9138 (2023)
Targeting Biomolecular Condensation and Protein Aggregation against Cancer. Chemical Reviews 18.
Journal Article
13 (4), pp. 633 - 636 (2023)
People with early onset Parkinson’s disease: empowered to improve care. Journal of Parkinson's Disease: JPD 19.
Journal Article
29 (33), e202300649 (2023)
Chemical Synthesis of Alpha-Synuclein Proteins via Solid-Phase Peptide Synthesis and Native Chemical Ligation. Chemistry – A European Journal 20.
Journal Article
14, 1918 (2023)
Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage. Nature Communications 21.
Journal Article
13 (2), pp. 179 - 196 (2023)
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy. Journal of Parkinson's Disease: JPD 22.
Journal Article
23, 174 (2023)
Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy. BMC Cancer 23.
Journal Article
177, 105995 (2023)
The immune system in Parkinson's disease: From biology to diagnosis and therapeutic targets. Neurobiology of Disease 24.
Journal Article
11 (8), 2209 (2023)
Genome-Wide Expression Profile in People with Optic Neuritis Associated with Multiple Sclerosis. Biomedicines 25.
Journal Article
11 (2), 505 (2023)
Stem Cell Therapies in Movement Disorders: Lessons from Clinical Trials. Biomedicines 26.
Journal Article
38 (2), pp. 162 - 177 (2022)
Type 2 Diabetes and Parkinson's Disease: A Focused Review of Current Concepts. Movement Disorders 27.
Journal Article
12, pp. 2397 - 2422 (2022)
Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity. Journal of Parkinson's Disease: JPD 28.
Journal Article
11 (22), 3673 (2022)
Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation. Cells 29.
Journal Article
269, 104721 (2022)
Ectosomes and exosomes modulate neuronal spontaneous activity. Journal of Proteomics 30.
Journal Article
Hexokinase 2: The preferential target of trehalose-6-phosphate over hexokinase 1. Journal of Cellular Biochemistry (2022)
31.
Journal Article
10 (1), 98 (2022)
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies. Acta Neuropathologica Communications 32.
Journal Article
168, 105696 (2022)
Extracellular alpha-synuclein: Sensors, receptors, and responses. Neurobiology of Disease 33.
Journal Article
7, 65 (2021)
Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. NPJ Parkinsons Disease 34.
Journal Article
87, pp. 70 - 85 (2021)
JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats. NeuroToxicology 35.
Journal Article
Molecular characterization of an aggregation-prone variant of alpha-synuclein used to model synucleinopathies. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics (2020)
36.
Journal Article
404, pp. 58 - 71 (2020)
Tapentadol Prevent Motor Impairments in a Mouse Model of Dyskinesia. Neuroscience 37.
Journal Article
116 (51), pp. 25991 - 2600 (2019)
Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1. Proceedings of the National Academy of Sciences of the United States of America 38.
Journal Article
28, pp. 65 - 77 (2019)
Cytosolic trapping of a mitochondrial heat shock protein is an early pathological event in synucleinopathies. Cell Reports 39.
Journal Article
47, pp. 909 - 918 (2019)
Investigating targets for neuropharmacological intervention by molecular dynamics simulations. Biochemical Society Transactions 40.
Journal Article
8, 18 (2019)
Dihydromyricetin and salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy. Translational neurodegeneration 41.
Journal Article
47 (3), pp. 827 - 838 (2019)
LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders? Biochemical Society Transactions 42.
Journal Article
85 (5), pp. 691 - 703 (2019)
Seeding variability of different alpha synuclein strains in synucleinopathies. Annals of Neurology 43.
Journal Article
12, 107 (2019)
Spreading of α-synuclein and tau: a systematic comparison of the mechanisms involved. Frontiers in Molecular Neuroscience 44.
Journal Article
22, 101135 (2019)
Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity. Redox Biology 45.
Journal Article
47, pp. 197 - 207 (2019)
The role of LRRK2 in cell signalling. Biochemical Society Transactions 46.
Journal Article
33 (2), pp. 2116 - 2131 (2019)
Monitoring α-synuclein multimerization in vivo. The FASEB Journal 47.
Journal Article
14, 5 (2019)
Dementia with Lewy bodies: an update and outlook. Molecular neurodegeneration 48.
Journal Article
27 (1), pp. 79 - 91 (2019)
Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorganic & Medicinal Chemistry 49.
Journal Article
28 (1), pp. 31 - 50 (2019)
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein. Human Molecular Genetics 50.
Journal Article
18 (8), foy108 (2018)
Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast. FEMS Yeast Research