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The role of LRRK2 in cell signalling. Biochemical Society Transactions 52.
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33 (2), pp. 2116 - 2131 (2019)
Monitoring α-synuclein multimerization in vivo. The FASEB Journal 53.
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Dementia with Lewy bodies: an update and outlook. Molecular neurodegeneration 54.
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27 (1), pp. 79 - 91 (2019)
Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorganic & Medicinal Chemistry 55.
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28 (1), pp. 31 - 50 (2019)
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein. Human Molecular Genetics 56.
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18 (8), foy108 (2018)
Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast. FEMS Yeast Research 57.
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33 (11), pp. 1675 - 1684 (2018)
Sensing α-Synuclein from the outside via the prion problem: implications for neurodegeneration. Movement Disorders 58.
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55, pp. 8754 - 8763 (2018)
Diabetes mellitus as a risk factor for Parkinson's disease: a molecular point of view. Molecular Neurobiology 59.
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38, pp. 1539 - 1550 (2018)
Secretion and uptake of α-synuclein via extracellular vesicles in cultured cells. Cellular and Molecular Neurobiology 60.
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The trehalose protective mechanism during thermal stress in Saccharomyces cerevisiae: the roles of Ath1 and Agt1. FEMS Yeast Research 61.
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Membrane binding, internalization, and sorting of alpha-synuclein in the cell. Acta Neuropathologica Communications 62.
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(Poly)phenol-digested metabolites modulate alpha-synuclein toxicity by regulating proteostasis. Scientific Reports 64.
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114 (5), pp. 1036 - 1045 (2018)
Binding modes of phthalocyanines of amyloid β peptide and their effects on amyloid fibril formation. Biophysical Journal 65.
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Attention-deficit/hyperactivity disorder is associated with reduced levels of serum low-density lipoprotein cholesterol in adolescents. Data from the population-based German KiGGS study. World journal of biological psychiatry, 10.1080/15622975.2017.1417636 (2018)
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37 (1), pp. 139 - 159 (2018)
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO Journal 67.
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55, pp. 5269 - 5281 (2018)
Implications of fALS mutations on Sod1 function and oligomerization in cell models. Molecular Neurobiology 68.
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5 (1), pp. 4 - 31 (2018)
Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell 69.
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8 (1), pp. 33 - 43 (2018)
Alpha-synuclein glycation and the action of anti-diabetic agents in Parkinson's disease. Journal of Parkinson's Disease: JPD 70.
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119, pp. 121 - 135 (2018)
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function. Neurobiology of Disease 71.
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115 (41), pp. 10481 - 10486 (2018)
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America 72.
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The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus. Diabetology & Metabolic Syndrome 73.
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20 (11), pp. 1569 - 1579 (2017)
Alpha-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B. Nature Neuroscience 74.
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Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson's disease. Scientific Reports 75.
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32 (9), pp. 1331 - 1333 (2017)
Neuromelanin magnetic resonance imaging of the Substantia Nigra in LRRK2-related Parkinson's disease. Movement Disorders 76.
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295, pp. 77 - 87 (2017)
Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease. Experimental Neurology 77.
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56, pp. 7 - 16 (2017)
Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway. Neurobiology of Aging 78.
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73 (4), pp. 459 - 467 (2017)
IGF-I gene therapy in aging rats modulates hippocampal genes relevant to memory function. Journals of Gerontology: Series A, Biological Sciences and Medical Sciences 79.
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26 (12), pp. 2231 - 2246 (2017)
Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage. Human Molecular Genetics 80.
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114 (25), pp. E4971 - E4977 (2017)
Treatment with diphenyl-pyrazole compound anle138b/c reveals that alpha-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 81.
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114 (25), pp. E4971 - E4977 (2017)
Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 82.
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The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biology 85.
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Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Scientific Reports 86.
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Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity. Human Molecular Genetics 87.
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37, pp. 121 - 131 (2017)
Cellular uptake of α-Synuclein oligomer-selective antibodies is enhanced by the extracellular presence of α-Synuclein and mediated via Fcγ receptors. Cellular and Molecular Neurobiology 88.
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40, pp. 168 - 181 (2017)
Cell reprogramming: Therapeutic potential and the promise of rejuvenation for the aging brain. Ageing Research Reviews 89.
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The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation. Acta Neuropathologica Communications 90.
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Glycation potentiates neurodegeneration in models of Huntington's disease. Scientific Reports 91.
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Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America 92.
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Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatonin. Molecular and Cellular Endocrinology 93.
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The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Scientific Reports 94.
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A familial ATP13A2 mutation enhances alpha-synuclein aggregation and promotes cell death. Human Molecular Genetics 95.
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C-terminal tyrosine residue modifications modulate the protective phosphorylation of Serine 129 of α-synuclein in a yeast model of Parkinson's disease. PLoS Genetics 96.
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Glycation in Parkinson's disease and Alzheimer's disease. Movement Disorders 97.
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shRNA-based screen identifiers endocytic recycling pathway components that act as genetic modifiers of alpha-synuclein aggregation, secretion and toxicity. PLoS Genetics 98.
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Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity. Human Molecular Genetics 99.
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Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells. Cell Death and Disease Book Chapter (3)
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