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Harvey, K.; Outeiro, T. F.: The role of LRRK2 in cell signalling. Biochemical Society Transactions 47, pp. 197 - 207 (2019)
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Prasad, V.; Wasser, Y.; Hans, F.; Goswami, A.; Katona, I.; Outeiro, T. F.; Kahle, P. J.; Schulz, J. B.; Voigt, A.: Monitoring α-synuclein multimerization in vivo. The FASEB Journal 33 (2), pp. 2116 - 2131 (2019)
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Outeiro, T. F.; Koss, D. J.; Erskine, D.; Walker, L.; Kurzawa-Akanbi, M.; Burn, D.; Donaghy, P.; Morris, C.; Taylor, J.-P.; Thomas, A. et al.; Atterns, J.; McKeith, I.: Dementia with Lewy bodies: an update and outlook. Molecular neurodegeneration 14, 5 (2019)
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Chiang, A. N.; Liang, M.; Dominguez-Meijide, A.; Masaracchia, C.; Goeckeler-Fried, J. L.; Mazzone, C. S.; Newhouse, D. W.; Kendsersky, N. M.; Yates, M. E.; Manos-Turvey, A. et al.; Needham, P. G.; Outeiro, T. F.; Wipf, P.; Brodsky, J. L.: Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorganic & Medicinal Chemistry 27 (1), pp. 79 - 91 (2019)
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Pinho , R.; Paiva, I.; Jercic, K. G.; Fonseca-Ornelas, L.; Gerhardt, E.; Fahlbusch, C.; Garcia-Esparcia, P.; Kerimoglu, C.; Pavlou, M. A.S.; Villar-Piqué, A. et al.; Szegö, É.; Lopes da Fonseca, T.; Odoardi, F.; Soeroes, S.; Rego, A. C.; Fischle, W.; Schwamborn, J. C.; Meyer, T.; Kügler, S.; Ferrer, I.; Attems, J.; Fischer, A.; Becker, S.; Zweckstetter, M.; Borovecki, F.; Outeiro, T. F.: Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein. Human Molecular Genetics 28 (1), pp. 31 - 50 (2019)
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Brás, I. C.; Tenreiro, S.; Silva, A. M.; Outeiro, T. F.: Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast. FEMS Yeast Research 18 (8), foy108 (2018)
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Brás, I. C.; Lopes, L. V.; Outeiro, T. F.: Sensing α-Synuclein from the outside via the prion problem: implications for neurodegeneration. Movement Disorders 33 (11), pp. 1675 - 1684 (2018)
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Biosa, A.; Outeiro, T. F.; Bubacco, L.; Bisaglia, M.: Diabetes mellitus as a risk factor for Parkinson's disease: a molecular point of view. Molecular Neurobiology 55, pp. 8754 - 8763 (2018)
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Gustafsson, G.; Lööv, C.; Persson, E.; Lázaro, D. F.; Takeda, S.; Bergström, J.; Erlandsson, A.; Sehlin, D.; Balaj, L.; György, B. et al.; Hallbeck, M.; Outeiro, T. F.; Breakefield, X. O.; Hyman, B. T.; Ingelsson, M.: Secretion and uptake of α-synuclein via extracellular vesicles in cultured cells. Cellular and Molecular Neurobiology 38, pp. 1539 - 1550 (2018)
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Magalhães, R. S.S.; Popova, B.; Braus, G. H.; Outeiro, T. F.; Eleutherio, E. C.A.: The trehalose protective mechanism during thermal stress in Saccharomyces cerevisiae: the roles of Ath1 and Agt1. FEMS Yeast Research 18 (6), foy066 (2018)
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Masaracchia, C.; Hnida, M.; Gerhardt, E.; Lopes da Fonseca, T.; Villar-Pique, A.; Branco, T.; Stahlberg, M. A.; Dean, C.; Fernández, C. O.; Milosevic, I. et al.; Outeiro, T. F.: Membrane binding, internalization, and sorting of alpha-synuclein in the cell. Acta Neuropathologica Communications 6, 79 (2018)
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Temido-Ferreira, M.; Ferreira, D. G.; Batalha, V. L.; Marques-Morgado, I.; Coelho, J. E.; Pereira, P.; Gomes, R.; Pinto, A.; Carvalho, S.; Canas, P. M. et al.; Cuvelier, L.; Buée-Scherrer, V.; Faivre, E.; Baqi, Y.; Müller, C. E.; Pimentel, J.; Schiffmann, S. N.; Buée, L.; Bader, M.; Outeiro, T. F.; Blum, D.; Cunha, R. A.; Marie, H.; Pousinha, P. A.; Lopes, L. V.: Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors. Molecular Psychiatry, 10.1038/s41380-018-0110-9 (2018)
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Macedo, D.; Jardim, C.; Figueira, I.; Almeida, A. F.; McDougall, G. J.; Stewart, D.; Yuste, J. E.; Tomás-Barberán, F. A.; Tenreiro, S.; Outeiro, T. F. et al.; Santos, C. N.: (Poly)phenol-digested metabolites modulate alpha-synuclein toxicity by regulating proteostasis. Scientific Reports 8, 6965 (2018)
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Valiente-Gabioud, A. A.; Riedel, D.; Outeiro, T. F.; Menacho-Márquez, M. A.; Griesinger, C.; Fernández, C. O.: Binding modes of phthalocyanines of amyloid β peptide and their effects on amyloid fibril formation. Biophysical Journal 114 (5), pp. 1036 - 1045 (2018)
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Pinho, R.; Wang, B.; Becker, A.; Rothenberger, A.; Outeiro, T. F.; Herrmann-Lingen, C.; Meyer, T.: Attention-deficit/hyperactivity disorder is associated with reduced levels of serum low-density lipoprotein cholesterol in adolescents. Data from the population-based German KiGGS study. World journal of biological psychiatry, 10.1080/15622975.2017.1417636 (2018)
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Richter, K. N.; Revelo, N. H.; Seitz, K. J.; Helm, M. S.; Sarkar, D.; Saleeb, R. S.; D'Este, E.; Eberle, J.; Wagner, E.; Vogl, C. et al.; Lazaro, D. F.; Richter, F.; Coy-Vergara, J.; Coceano, G.; Boyden, E. S.; Duncan, R. R.; Hell, S. W.; Lauterbach, M. A.; Lehnart, S. E.; Moser, T.; Outeiro, T. F.; Rehling, P.; Schwappach, B.; Testa, I.; Zapiec, B.; Rizzoli, S. O.: Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO Journal 37 (1), pp. 139 - 159 (2018)
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Brasil, A. A.; Magalhães, R. S. S.; De Carvalho, M. D. C.; Paiva, I.; Gerhardt, E.; Pereira, M. D.; Outeiro, T. F.; Eleutherio, E. C. A.: Implications of fALS mutations on Sod1 function and oligomerization in cell models. Molecular Neurobiology 55, pp. 5269 - 5281 (2018)
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Carmona-Gutierrez, D.; Bauer, M. A.; Zimmermann, A.; Aguilera, A.; Austriaco, N.; Ayscough, K.; Balzan, R.; Bar-Nun, S.; Barrientos, A.; Belenky, P. et al.; Blondel, M.; Braun, R. J.; Breitenbach, M.; Burhans, W. C.; Büttner, S.; Cavalieri, D.; Chang, M.; Cooper, K. F.; Côrte-Real, M.; Costa, V.; Cullin, C.; Dawes, I.; Dengjel, J.; Dickman, M. B.; Eisenberg, T.; Fahrenkrog, B.; Fasel, N.; Fröhlich, K.-U.; Gargouri, A.; Giannattasio, S.; Goffrini, P.; Gourlay, C. W.; Grant, C. M.; Greenwood, M. T.; Guaragnella, N.; Heger, T.; Heinisch, J.; Herker, E.; Herrmann, J. M.; Hofer, S.; Jiménez-Ruiz, A.; Jungwirth, H.; Kainz, K.; Kontoyiannis, D. P.; Ludovico, P.; Manon, S.; Martegani, E.; Mazzoni, C.; Megeney, L. A.; Meisinger, C.; Nielsen, J.; Nyström, T.; Osiewacz, H. D.; Outeiro, T. F.; Park, H.-O.; Pendl, T.; Petranovic, D.; Picot, S.; Polčic, P.; Powers, T.; Ramsdale, M.; Rinnerthaler, M.; Rockenfeller, P.; Ruckenstuhl, C.; Schaffrath, R.; Segovia, M.; Severin, F. F.; Sharon, A.; Sigrist, S. J.; Sommer-Ruck, C.; Sousa, M. J.; Thevelein, J. M.; Thevissen, K.; Titorenko, V.; Toledano, M. B.; Tuite, M.; Vögtle, F.-N.; Westermann, B.; Winderickx, J.; Wissing, S.; Wölfl, S.; Zhang, Z. J.; Zhao, R. Y.; Zhou, B.; Galluzzi, L.; Kroemer, G.; Madeo, F.: Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell 5 (1), pp. 4 - 31 (2018)
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König, A.; Miranda, H. V.; Outeiro, T. F.: Alpha-synuclein glycation and the action of anti-diabetic agents in Parkinson's disease. Journal of Parkinson's Disease: JPD 8 (1), pp. 33 - 43 (2018)
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Paiva, I.; Jain, G.; Lázaro, D. F.; Gotovac Jercic, K.; Hentrich, T.; Kerimoglu, C.; Pinho, R.; Szego, È. M.; Burkhardt, S.; Capece, V. et al.; Halder, R.; Islam, R.; Xylaki, M.; Caldi Gomes, L. A.; Roser, A.-E.; Lingor, P.; Schulze-Hentrich, J. M.; Borovecki, F.; Fischer, A.; Outeiro, T. F.: Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function. Neurobiology of Disease 119, pp. 121 - 135 (2018)
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Pujols, J.; Peña-Díaz, S.; Lázaro, D. F.; Peccati, F.; Pinheiro, F.; González, D.; Carija, A.; Navarro, S.; Conde-Giménez, M.; García, J. et al.; Guardiola, S.; Giralt, E.; Salvatella, X.; Sancho, J.; Sodupe, M.; Outeiro, T. F.; Dalfó, E.; Ventura, S.: Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America 115 (41), pp. 10481 - 10486 (2018)
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Bozek, T.; Blazekovic, A.; Nikolac Perkovic, M.; Gotovac Jercic, K.; Sustar, A.; Smircic-Duvnjak, L.; Outeiro, T. F.; Pivac, N.; Borovecki, F.: The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus. Diabetology & Metabolic Syndrome 9, 97 (2017)
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Ferreira, D. G.; Temido-Ferreira, M.; Miranda, H. V.; Batalha, V. L.; Coelho, J. E.; Szegö, É. M.; Marques-Morgado, I.; Vaz, S. H.; Rhee, J. S.; Schmitz, M. et al.; Zerr, I.; Lopes, L. V.; Outeiro, T. F.: Alpha-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B. Nature Neuroscience 20 (11), pp. 1569 - 1579 (2017)
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Miranda, H. V.; Cássio, R.; Correia-Guedes, L.; Gomes, M. A.; Chegão, A.; Miranda, E.; Soares, T.; Coelho, M.; Rosa, M. M.; Ferreira, J. J. et al.; Outeiro, T. F.: Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson's disease. Scientific Reports 7, 13713 (2017)
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Guedes, L. C.; Reimão, S.; Paulino, P.; Nunes, R. G.; Bouça-Machado, R.; Abreu, D.; Gonçalves, N.; Soares, T.; Fabbri, M.; Godinho, C. et al.; Lobo, P. P.; Neutel, D.; Quadri, M.; Coelho, M.; Rosa, M. M.; Campos, J.; Outeiro, T. F.; Sampaio, C.; Bonifati, V.; Ferreira, J. J.: Neuromelanin magnetic resonance imaging of the Substantia Nigra in LRRK2-related Parkinson's disease. Movement Disorders 32 (9), pp. 1331 - 1333 (2017)
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Moreira, S.; Fonseca, I.; Nunes, M. J.; Rosa, A.; Lemos, L.; Rodrigues, E.; Neves Carvalho, A.; Outeiro, T. F.; Pereira Rodrigues, C. M.; Gama, M. J. et al.; Castro-Caldas, M.: Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease. Experimental Neurology 295, pp. 77 - 87 (2017)
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Szegö, É. M.; Gerhardt, E.; Outeiro, T. F.: Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway. Neurobiology of Aging 56, pp. 7 - 16 (2017)
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Pardo, J.; Abba , M. C.; Lacunza, E.; Ogundele, O. M.; Paiva, I.; Morel, G. R.; Outeiro, T. F.; Goya, R. G.: IGF-I gene therapy in aging rats modulates hippocampal genes relevant to memory function. Journals of Gerontology: Series A, Biological Sciences and Medical Sciences 73 (4), pp. 459 - 467 (2017)
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Paiva, I.; Pinho, R.; Pavlou, M. A.; Hennion, M.; Wales, P.; Schütz, A.-L.; Rajput, A.; Szegö, É. M.; Kerimoglu, C.; Gerhardt, E. et al.; Rego, A. C.; Fischer, A.; Bonn, S.; Outeiro, T. F.: Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage. Human Molecular Genetics 26 (12), pp. 2231 - 2246 (2017)
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Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. et al.; Becker, D.: Treatment with diphenyl-pyrazole compound anle138b/c reveals that alpha-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25), pp. E4971 - E4977 (2017)
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Turriani, E.; Lázaro, D. F.; Ryazanov, S.; Leonov, A.; Giese, A.; Schön, M.; Schön, M. P.; Griesinger, C.; Outeiro, T. F.; Arndt-Jovin, D. J. et al.; Becker, D.: Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death. Proceedings of the National Academy of Sciences of the United States of America 114 (25), pp. E4971 - E4977 (2017)
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Miranda, H. V.; Szegö, É. M.; Oliveira, L. M. A.; Breda, C.; Darendelioglu, E.; Oliveira, R. M. d.; Ferreira, D. G.; Gomes, M. A.; Rott, R.; Oliveira, M. et al.; Munari, F.; Enguita, F. J.; Simões, T.; Rodrigues, E. F.; Heinrich, M.; Martins, I. C.; Zamolo, I.; Riess, O.; Cordeiro, C.; Ponces-Freire, A.; Lashuel, H. A.; Santos, N. C.; Lopes, L. V.; Xiang, W.; Jovin, T. M.; Penque, D.; Engelender, S.; Zweckstetter, M.; Klucken, J.; Giorgini, F.; Quintas, A.; Outeiro, T. F.: Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies. Brain 140, pp. 1399 - 1419 (2017)
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Pavlou, M. A. S.; Pinho, R.; Paiva, I.; Outeiro, T. F.: The yin and yang of α-synuclein-associated epigenetics in Parkinson's disease. Brain 140, pp. 878 - 886 (2017)
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Machado de Oliveira, R.; Miranda, H. V.; Francelle, L.; Pinho, R.; Szegö, É. M.; Martinho, R.; Munari, F.; Lázaro, D. F.; Moniot, S.; Guerreiro, P. et al.; Fonseca, L.; Marijanovic, Z.; Antas, P.; Gerhardt, E.; Enguita, F. J.; Fauvet, B.; Penque, D.; Pais, T. F.; Tong, Q.; Becker, S.; Kügler, S.; Lashuel, H. A.; Steegborn, C.; Zweckstetter, M.; Outeiro, T. F.: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biology 15 (3), e1002601 (2017)
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Menges, S.; Minakaki, G.; Schaefer, P. M.; Meixner, H.; Prots, I.; Schlötzer-Schrehardt, U.; Friedland, K.; Winner, B.; Outeiro, T. F.; Winklhofer, K. F. et al.; von Arnim, C. A. F.; Xiang, W.; Winkler, J.; Klucken, J.: Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Scientific Reports 7, 42942 (2017)
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Branco-Santos, J.; Herrera, F.; Poças, G. M.; Pires-Afonso, Y.; Giorgini, F.; Domingos, P. M.; Outeiro, T. F.: Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity. Human Molecular Genetics 26 (19), pp. 3763 - 3775 (2017)
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Gustafsson, G.; Eriksson, F.; Möller, C.; Lopes da Fonseca, T.; Outeiro, T. F.; Lannfelt, L.; Bergström, J.; Ingelsson, M.: Cellular uptake of α-Synuclein oligomer-selective antibodies is enhanced by the extracellular presence of α-Synuclein and mediated via Fcγ receptors. Cellular and Molecular Neurobiology 37, pp. 121 - 131 (2017)
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López-León, M.; Outeiro, T. F.; Goya, R. G.: Cell reprogramming: Therapeutic potential and the promise of rejuvenation for the aging brain. Ageing Research Reviews 40, pp. 168 - 181 (2017)
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Lázaro, D. F.; Castro Dias, M.; Carija, A.; Navarro, S.; Silva Madaleno, C.; Tenreiro, S.; Ventura, S.; Outeiro, T. F.: The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation. Acta Neuropathologica Communications 4, 128 (2016)
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Miranda, H. V.; Gomes, M. A.; Branco-Santos, J.; Breda, C.; Lázaro, D. F.; Vaqueiro Lopes, L.; Herrera, F.; Giorgini, F.; Outeiro, T. F.: Glycation potentiates neurodegeneration in models of Huntington's disease. Scientific Reports 6, 36798 (2016)
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Villar-Piqué, A.; Lopes da Fonseca, T.; Sant'Anna, R.; Szegö, É. M.; Fonseca-Ornelas, L.; Pinho, R.; Carija, A.; Gerhardt, E.; Masaracchia, C.; Gonzalez, E. A. et al.; Rossetti, G.; Carloni, P.; Fernández, C. O.; Foguel, D.; Milosevic, I.; Zweckstetter, M.; Ventura, S.; Outeiro, T. F.: Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America 113 (42), pp. E6506 - E6515 (2016)
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Letra-Vilela, R.; Sánchez-Sánchez, A. M.; Rocha, A. M.; Martin, V.; Branco-Santos, J.; Puente-Moncada, N.; Santa-Marta, M.; Outeiro, T. F.; Antolín, I.; Rodriguez, C. et al.; Herrera, F.: Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatonin. Molecular and Cellular Endocrinology 434, pp. 238 - 249 (2016)
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Lopes da Fonseca, T.; Pinho, R.; Outeiro, T. F.: A familial ATP13A2 mutation enhances alpha-synuclein aggregation and promotes cell death. Human Molecular Genetics 25 (14), pp. 2959 - 2971 (2016)
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Kleinknecht, A.; Popova, B.; Lázaro, D. F.; Pinho, R.; Valerius, O.; Outeiro, T. F.; Braus, G. H.: C-terminal tyrosine residue modifications modulate the protective phosphorylation of Serine 129 of α-synuclein in a yeast model of Parkinson's disease. PLoS Genetics 12 (6), e1006098 (2016)
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Goncalves, S. A.; Macedo, D.; Raquel, H.; Simões, P. D.; Giorgini, F.; Ramalho, J. S.; Barral, D. C.; Moita, L. F.; Outeiro, T. F.: shRNA-based screen identifiers endocytic recycling pathway components that act as genetic modifiers of alpha-synuclein aggregation, secretion and toxicity. PLoS Genetics 12, e1005995 (2016)
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Tenreiro, S.; Rosado-Ramos, R.; Gerhardt, E.; Favretto, F.; Magalhães, F.; Popova, B.; Becker, S.; Zweckstetter, M.; Braus, G. H.; Outeiro, T. F.: Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity. Human Molecular Genetics 25 (2), pp. 275 - 290 (2016)
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Book Chapter (3)

100.
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Del-Bel, E.; Bortolanza, M.; Do Nascimento, G.C.; Raisman-Vozari, R.; Dos Santos Pereira, M.; González-Lizárraga, F.; Parrales, V.; Michel, P.; Ploper, D.; Ávila, C.L. et al.; Socias, S.; Outeiro, T. F.; Chehin, R.: Doxycycline Therapeutic Approach in Parkinson’s Disease and L-DOPA-Induced Dyskinesia. In: Handbook of Neurotoxicity, pp. 1539 - 1559 (Ed. Kostrzewa, R. M.). Springer, Cham (2022)
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