Publications of Fabian Rabe von Pappenheim

Mrozek, P.; Grunewald, S.; Treffon, K.; Poschmann, G.; Rabe von Pappenheim, F.; Tittmann, K.; Gatz, C.: Molecular basis for the enzymatic inactivity of class III glutaredoxin ROXY9 on standard glutathionylated substrates. Nature Communications 16, 589 (2025)

Lanza, L.; Rabe von Pappenheim, F.; Bjarnesen, D.; Leogrande, C.; Paul, A.; Krug, L.; Tittmann, K.; Müller, M.: Identification and Characterization of Thiamine Diphosphate‐Dependent Lyases with an Unusual CDG Motif. Angewandte Chemie International Edition 63 (34), e202404045 (2024)

Funk, L.-M.; Poschmann, G.; Rabe von Pappenheim, F.; Chari, A.; Stegmann, K. M.; Dickmanns, A.; Wensien, M.; Eulig, N.; Paknia, E.; Heyne, G. et al.; Penka, E.; Pearson, A. R.; Berndt, C.; Fritz, T.; Bazzi, S.; Uranga, J.; Mata, R. A.; Dobbelstein, M.; Hilgenfeld, R.; Curth, U.; Tittmann, K.: Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design. Nature Communications 15, 411 (2024)

Prajapati, S.; Rabe von Pappenheim, F.; Tittmann, K.: Frontiers in the enzymology of thiamin diphosphate-dependent enzymes. Current Opinion in Structural Biology 76, 102441 (2022)

Rindfleisch, S.; Krull, M.; Uranga, J.; Schmidt, T.; Rabe von Pappenheim, F.; Kirck, L. L.; Balouri, A.; Schneider, T.; Chari, A.; Kluger, R. et al.; Bourenkov, G.; Diederichsen, U.; Mata, R. A.; Tittmann, K.: Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5′-monophosphate decarboxylase catalysis. Nature Catalysis 5, pp. 332 - 341 (2022)

Wensien, M.; Rabe von Pappenheim, F.; Funk, L. M.; Kloskowski, P.; Curth, U.; Diederichsen, U.; Uranga, J.; Ye, J.; Fang, P.; Pan, K. T. et al.; Urlaub, H.; Mata, R. A.; Sautner, V.; Tittmann, K.: A lysine–cysteine redox switch with an NOS bridge regulates enzyme function. Nature 593 (7859), pp. 460 - 464 (2021)

Rabe von Pappenheim, F.; Aldeghi, M.; Shome, B.; Begley, T.; de Groot, B. L.; Tittmann, K.: Structural basis for antibiotic action of the B1 antivitamin 2′-methoxy-thiamine. Nature Chemical Biology 16 (11), p. 1237-1245 (2020)