Publications
Journal Article (95)
1.
Journal Article
MINSTED nanoscopy enters the Ångström localization range. Nature Biotechnology (2022)
2.
Journal Article
13, 6172 (2022)
A simple thermodynamic description of phase separation of Nup98 FG domains. Nature Communications 3.
Journal Article
114, pp. 22 - 32 (2022)
An In Vivo Model for Elucidating the Role of an Erythroid-Specific Isoform of Nuclear Export Protein Exportin 7 (Xpo7) in Murine Erythropoiesis. Experimental Hematology 4.
Journal Article
12, 15069 (2022)
Compellingly high SARS-CoV-2 susceptibility of Golden Syrian hamsters suggests multiple zoonotic infections of pet hamsters during the COVID-19 pandemic. Scientific Reports 5.
Journal Article
13, 1494 (2022)
Atomic resolution dynamics of cohesive interactions in phase-separated Nup98 FG domains. Nature Communications 6.
Journal Article
40 (19), e107985 (2021)
Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 7.
Journal Article
302, 198469 (2021)
The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models. Virus Research 8.
Journal Article
12, 4047 (2021)
Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide. Nature Communications 9.
Journal Article
14 (8), pp. 9938 - 9952 (2020)
A method to quantify molecular diffusion within thin solvated polymer films: A case study on films of natively unfolded nucleoporins. ACS Nano 10.
Journal Article
52 (2), pp. 210 - 222 (2020)
F-actin interactome reveals vimentin as a key regulator of actin organization and cell mechanics in mitosis. Developmental Cell 11.
Journal Article
87 (7-8), pp. 221 - 230 (2019)
Promiscuous dimerization between the Caenorhabditis elegans IF proteins and a hypothesis to explain how multiple IFs persist over evolutionary time. Journal of Molecular Evolution 12.
Journal Article
94 (1), pp. 25 - 38 (2019)
Releasing the concept of HLA-allele specific peptide anchors in viral infections: A non-canonical naturally presented human cytomegalovirus-derived HLA-A*24:02 restricted peptide drives exquisite immunogenicity. HLA: Immune Response Genetics 13.
Journal Article
218 (6), pp. 1839 - 1852 (2019)
Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. Journal of Cell Biology 14.
Journal Article
218 (6), pp. 2006 - 2020 (2019)
Engineered SUMO/protease system identifies Pdr6 as a bidirectional nuclear transport receptor. The Journal of Cell Biology 15.
Journal Article
51 (5-6), pp. 353 - 360 (2019)
HLA-F*01:01 presents peptides with N-terminal flexibility and a preferred length of 16 residues. Immunogenetics 16.
Journal Article
20 (6), 1454 (2019)
Between innate and adaptive immune responses: NKG2A, NKG2C, and CD8⁺ T cell recognition of HLA-E restricted self-peptides acquired in the absence of HLA-Ia. International Journal of Molecular Sciences 17.
Journal Article
8, 16913 (2018)
The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Scientific Reports 18.
Journal Article
2018, 5086503 (2018)
Carbamazepine-mediated adverse drug reactions: CBZ-10,11-epoxide but not carbamazepine induces the alteration of peptides presented by HLA-B*15:02. Journal of Immunology Research 19.
Journal Article
217 (7), pp. 2329 - 2340 (2018)
Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 20.
Journal Article
174 (1), pp. 202 - 217 (2018)
Surface properties determining passage rates of proteins through nuclear pores. Cell 21.
Journal Article
373 (1748), 20170337 (2018)
Excision of the doubly methylated base N-4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins. Philosophical Transactions of the Royal Society B: Biological Sciences 22.
Journal Article
79 (6), pp. 453 - 462 (2018)
HLA-G mediated immune regulation is impaired by a single amino acid exchange in the alpha 2 domain. Human Immunology 23.
Journal Article
14 (18), 1703357 (2018)
Reversible immobilization of proteins in sensors and solid-state nanopores. Small 24.
Journal Article
6 (2), 18 (2018)
The use of Hoechst dyes for DNA staining and beyond. Chemosensors 25.
Journal Article
217 (3), pp. 1143 - 1154 (2018)
A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. Journal of Cell Biology 26.
Journal Article
7, e31510 (2018)
Spatial structure of disordered proteins dictates conductance and selectivity in Nuclear Pore Complex mimics. eLife 27.
Journal Article
74 (3), pp. 107 - 113 (2017)
Assembly studies of six intestinal intermediate filament (IF) proteins B2, C1, C2, D1, D2, and E1 in the nematode C-elegans. Cytoskeleton 28.
Journal Article
114 (9), pp. 2125 - 2130 (2017)
Strong signal increase in STED fluorescence microscopy by imaging regions of subdiffraction extent. Proceedings of the National Academy of Sciences of the United States of America 29.
Journal Article
25 (24), pp. 5353 - 5364 (2016)
Effects of the Bowen-Conradi syndrome mutation in EMG1 on its nuclear import, stability and nucleolar recruitment. Human Molecular Genetics 30.
Journal Article
204 (1), pp. 191 - 203 (2016)
Axonopathy in the central nervous system is the hallmark of mice with a novel intragenic null mutation of dystonin. Genetics 31.
Journal Article
9 (434), ra66 (2016)
The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation. Science Signaling 32.
Journal Article
7, 11952 (2016)
Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A. Nature Communications 33.
Journal Article
5, e14119 (2016)
A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies. eLife 34.
Journal Article
41 (1), pp. 46 - 61 (2016)
Transport selectivity of nuclear pores, phase separation, and membraneless organelles. Trends in Biochemical Sciences 35.
Journal Article
4, e11466 (2015)
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. eLife 36.
Journal Article
4, e11349 (2015)
Nanobodies: Site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. eLife 37.
Journal Article
350 (6256), pp. 106 - 110 (2015)
Crystal structure of the metazoan Nup62•Nup58•Nup54 nucleoporin complex. Science 38.
Journal Article
10 (4), e0125099 (2015)
The Xenopus laevis Atg4B protease: Insights into substrate recognition and application for tag removal from proteins expressed in pro- and eukaryotic hosts. PLOS One 39.
Journal Article
4, e04251 (2015)
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity. eLife 40.
Journal Article
35 (32), pp. 8903 - 8915 (2014)
Well-defined biomimetic surfaces to characterize glycosaminoglycan-mediated interactions on the molecular, supramolecular and cellular levels. Biomaterials 41.
Journal Article
124 (12), pp. 1931 - 1940 (2014)
Histones to the cytosol: Exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood 42.
Journal Article
251 (4), pp. 985 - 988 (2014)
Unusual ultrastructures of the Branchiostoma IF protein C2 containing heptads in the tail. Protoplasma 43.
Journal Article
1337, pp. 95 - 105 (2014)
A new set of highly efficient, tag-cleaving proteases for purifying recombinant proteins. Journal of Chromatography A 44.
Journal Article
1337, pp. 106 - 115 (2014)
Purification of protein complexes of defined subunit stoichiometry using a set of orthogonal, tag-cleaving proteases. Journal of Chromatography A 45.
Journal Article
105 (8), pp. 1860 - 1870 (2013)
Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks - Implications for nuclear pore permeability. Biophysical Journal 46.
Journal Article
32 (13), pp. 1886 - 1902 (2013)
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO Journal 47.
Journal Article
11 (6), e1001577 (2013)
Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 48.
Journal Article
32 (2), pp. 204 - 218 (2013)
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO Journal 49.
Journal Article
91 (10), pp. 800 - 808 (2012)
A rod domain sequence in segment 1B triggers dimerisation of the two small Branchiostoma IF proteins B2 and A3. European Journal of Cell Biology 50.
Journal Article
150 (4), pp. 738 - 751 (2012)
The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell 51.
Journal Article
13 (6), pp. 1882 - 1889 (2012)
Structural characterization of nanoscale meshworks within a nucleoporin FG hydrogel. Biomacromolecules 52.
Journal Article
13 (8), pp. 2322 - 2332 (2012)
Viscoelasticity of thin biomolecular films: A case study on nucleoporin phenylalanine-glycine repeats grafted to a histidine- tag capturing QCM-D sensor. Biomacromolecules 53.
Journal Article
21 (3), pp. 445 - 456 (2011)
A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets. Developmental Cell 54.
Journal Article
30 (17), pp. 3457 - 3474 (2011)
Ran-dependent nuclear export mediators: A structural perspective. EMBO Journal 55.
Journal Article
50 (17), pp. 3993 - 3997 (2011)
Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements. Angewandte Chemie International Edition 56.
Journal Article
17 (11), pp. 1367 - 1376 (2010)
NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nature Structural and Molecular Biology 57.
Journal Article
29 (10), pp. 1659 - 1673 (2010)
Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion. EMBO Journal 58.
Journal Article
11 (5), pp. 366 - 372 (2010)
Ultrathin nucleoporin FG repeat films and their interaction with nuclear transport receptors. EMBO Reports 59.
Journal Article
107 (14), pp. 6281 - 6285 (2010)
Amyloid-like interactions within nucleoporin FG hydrogels. Proceedings of the National Academy of Sciences of the United States of America 60.
Journal Article
390 (2), pp. 235 - 240 (2009)
Transport of hypoxia-inducible factor HIF-1α into the nucleus involves importins 4 and 7. Biochemical and Biophysical Research Communications 61.
Journal Article
28, pp. 2541 - 2553 (2009)
Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO Journal 62.
Journal Article
28, pp. 2554 - 2567 (2009)
FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO Journal 63.
Journal Article
324 (5930), pp. 1087 - 1091 (2009)
Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Science 64.
Journal Article
185 (1), pp. 27 - 34 (2009)
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. Journal of Cell Biology 65.
Journal Article
37 (7), e50 (2009)
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci. Nucleic Acids Research 66.
Journal Article
130 (3), pp. 512 - 523 (2007)
A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes. Cell 67.
Journal Article
314 (5800), pp. 815 - 817 (2006)
FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science 68.
Journal Article
173 (4), pp. 509 - 519 (2006)
NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes. Journal of Cell Biology 69.
Journal Article
173 (4), pp. 477 - 483 (2006)
Nuclear pore complex assembly and maintenance in POM121-and gp210-deficient cells. Journal of Cell Biology 70.
Journal Article
8 (3), pp. 257 - 263 (2006)
A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes. Nature Cell Biology 71.
Journal Article
17, pp. 2646 - 2660 (2006)
NuSAP, a mitotic RanGTP target that stabilizes and crosslinks microtubules. Molecular Biology of the Cell 72.
Journal Article
19 (4), pp. 461 - 473 (2005)
Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl. Molecular Cell 73.
Journal Article
22 (14), pp. 3675 - 3685 (2003)
Nuclear import of HIV‐1 intracellular reverse transcription complexes is mediated by importin 7. The EMBO Journal 74.
Journal Article
21 (22), pp. 6205 - 6215 (2002)
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. The EMBO Journal 75.
Journal Article
289 (2), pp. 186 - 191 (2001)
Adenoviral E1A protein nuclear import is preferentially mediated by importin α3 in vitro. Virology 76.
Journal Article
114 (19), pp. 3479 - 3485 (2001)
Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin. Journal of Cell Science 77.
Journal Article
8 (5), pp. 495 - 505 (2001)
Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis. Cell Death and Differentiation 78.
Journal Article
275 (51), pp. 40163 - 40168 (2000)
Identification of Two novel RanGTP-binding proteins belonging to the importin β superfamily. The Journal of Biological Chemistry 79.
Journal Article
156 (4), pp. 1889 - 1900 (2000)
The Ketel gene encodes a Drosophila homologue of importin-β. Genetics 80.
Journal Article
39 (38), pp. 11629 - 11639 (2000)
Different structural and kinetic requirements for the interaction of Ran with the Ran-binding domains from RanBP2 and importin-β. Biochemistry 81.
Journal Article
10 (8), pp. 467 - 470 (2000)
Acetylation of importin-α nuclear import factors by CBP/p300. Current Biology 82.
Journal Article
6 (1), pp. 136 - 158 (2000)
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA 83.
Journal Article
19 (11), pp. 7782 - 7791 (1999)
Evidence for distinct substrate specificities of importin α family members in nuclear protein import. Molecular and Cellular Biology 84.
Journal Article
17 (10), pp. 2721 - 2727 (1998)
Transport into and out of the cell nucleus. The EMBO Journal 85.
Journal Article
16 (20), pp. 6237 - 6249 (1997)
Yrb4p, a yeast Ran–GTP‐binding protein involved in import of ribosomal protein L25 into the nucleus. The EMBO Journal 86.
Journal Article
17 (9), pp. 5087 - 5096 (1997)
Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin-beta but interacts differently with RanBP1. Molecular and Cellular Biology 87.
Journal Article
24 (17), pp. 3332 - 03336 (1996)
A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing. Nucleic Acids Research 88.
Journal Article
362 (2), pp. 126 - 130 (1995)
The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum. FEBS Letters 89.
Journal Article
126 (4), pp. 925 - 934 (1994)
Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex. The Journal of Cell Biology 90.
Journal Article
268 (35), pp. 26745 - 26751 (1993)
Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence. The Journal of Biological Chemistry 91.
Journal Article
214 (2), pp. 375 - 381 (1993)
A tetrameric complex of membrane proteins in the endoplasmic reticulum. European Journal of Biochemistry 92.
Journal Article
121 (4), pp. 743 - 750 (1993)
Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion. The Journal of Cell Biology 93.
Journal Article
113 (1), pp. 35 - 44 (1991)
The identification of proteins in the proximity of signal-anchor sequences during their targeting to and insertion into the membrane of the ER. The Journal of Cell Biology 94.
Journal Article
53 (2), pp. 197 - 202 (1990)
Segregation of the signal sequence receptor protein in the rough endoplasmic reticulum membrane. European Journal of Cell Biology 95.
Journal Article
257 (2), pp. 263 - 268 (1989)
Photocrosslinking demonstrates proximity of a 34 kDa membrane protein to different portions of preprolactin during translocation through the endoplasmic reticulum. FEBS Letters Book Chapter (1)
96.
Book Chapter
Nucleocytoplasmic transport. In: Protein targeting, transport, and translocation, pp. 293 - 321 (Ed. Dalbey, R. E.). Acad. Pr., Amsterdam (2002)
Editorial (1)
97.
Editorial
428 (10), pp. 1947 - 1948 (2016)
Editorial overview: Functional and mechanistic landscape of the nuclear pore complex. Journal of Molecular Biology Preprint (2)
98.
Preprint
Barrier-properties of Nup98 FG phases ruled by FG motif identity and inter-FG spacer length. (2022)
99.
Preprint
Nuclear basket protein ZC3HC1 and its yeast homolog Pml39p feature an evolutionary conserved bimodular construction essential for initial binding to NPC-anchored homologs of scaffold protein TPR. (2022)