Publications

2.

Journal Article

Ng, S. C.; Biswas, A.; Huyton, T.; Schünemann, J.; Reber, S.; Görlich, D.: Barrier-properties of Nup98 FG phases ruled by FG motif identity and inter-FG spacer length. Nature Communications 14, 747 (2023)

MPG.PuRe

3.

Journal Article

Loreau, V.; Rees, R.; Chan, E. H.; Taxer, W.; Gregor, K.; Mußil, B.; Pitaval, C.; Luis, N. M.; Mangeol, P.; Schnorrer, F. et al.; Görlich, D.: A nanobody toolbox to investigate localisation and dynamics of Drosophila titins and other key sarcomeric proteins. eLife 12, e79343 (2023)

MPG.PuRe

4.

Journal Article

Schueder, F.; Mangeol, P.; Chan, E. H.; Rees, R.; Schünemann, J.; Jungmann, R.; Görlich, D.; Schnorrer, F.: Nanobodies combined with DNA-PAINT super-resolution reveal a staggered titin nanoarchitecture in flight muscles. eLife 12, e79344 (2023)

MPG.PuRe

5.

Journal Article

Weber, M.; von der Emde, H.; Leutenegger, M.; Gunkel, P.; Sambandan, S.; Khan, T. A.; Keller-Findeisen, J.; Cordes, V. C.; Hell, S. W.: MINSTED nanoscopy enters the Ångström localization range. Nature Biotechnology (2022)

MPG.PuRe

6.

Journal Article

Ng, S. C.; Görlich, D.: A simple thermodynamic description of phase separation of Nup98 FG domains. Nature Communications 13, 6172 (2022)

MPG.PuRe

pre-print

7.

Journal Article

Huyton, T.; Jaiswal, M.; Taxer, W.; Fischer, M.; Görlich, D.: Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins. Scientific Reports 12, 16430 (2022)

MPG.PuRe

8.

Journal Article

Modepalli, S.; Martinez-Morilla, S.; Venkatesan , S.; Fasano, J.; Paulsen, K.; Görlich, D.; Hattangadi, S.; Kupfer, G. M.: An In Vivo Model for Elucidating the Role of an Erythroid-Specific Isoform of Nuclear Export Protein Exportin 7 (Xpo7) in Murine Erythropoiesis. Experimental Hematology 114, pp. 22 - 32 (2022)

MPG.PuRe

9.

Journal Article

Blaurock, C.; Breithaupt, A.; Weber, S.; Wylezich, C.; Keller, M.; Mohl, B.-P.; Görlich, D.; Groschup, M. H.; Sadeghi, B.; Höper, D. et al.; Mettenleiter, T. C.; Balkema-Buschmann, A.: Compellingly high SARS-CoV-2 susceptibility of Golden Syrian hamsters suggests multiple zoonotic infections of pet hamsters during the COVID-19 pandemic. Scientific Reports 12, 15069 (2022)

MPG.PuRe

10.

Journal Article

Gunkel, P.; Cordes, V. C.: ZC3HC1 is a structural element of the nuclear basket effecting interlinkage of TPR polypeptides. Molecular Biology of the Cell 33 (9), ar82 (2022)

MPG.PuRe

11.

Journal Article

Najbauer, E. E.; Ng, S. C.; Griesinger, C.; Görlich, D.; Andreas, L. B.: Atomic resolution dynamics of cohesive interactions in phase-separated Nup98 FG domains. Nature Communications 13, 1494 (2022)

MPG.PuRe

12.

Journal Article

Güttler, T.; Aksu, M.; Dickmanns, A.; Stegmann, K. M.; Gregor, K.; Rees, R.; Taxer, W.; Rymarenko, O.; Schünemann, J.; Dienemann, C. et al.; Gunkel, P.; Mussil, B.; Krull, J.; Teichmann, U.; Groß, U.; Cordes, V.; Dobbelstein, M.; Görlich, D.: Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 40 (19), e107985 (2021)

MPG.PuRe

13.

Journal Article

Stegmann, K. M.; Dickmanns, A.; Gerber, S.; Nikolova, V.; Klemke, L.; Manzini, V.; Schlösser, D.; Bierwirth, C.; Freund, J.; Sitte, M. et al.; Lugert, R.; Salinas, G.; Meister, T. L.; Pfaender, S.; Görlich, D.; Wollnik, B.; Groß, U.; Dobbelstein, M.: The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models. Virus Research 302, 198469 (2021)

MPG.PuRe

14.

Journal Article

Ng, S. C.; Güttler, T.; Görlich, D.: Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide. Nature Communications 12, 4047 (2021)

MPG.PuRe

15.

Journal Article

Frost, R.; Débarre, D.; Jana, S.; Bano, F.; Schünemann, J.; Görlich, D.; Richter, R. P.: A method to quantify molecular diffusion within thin solvated polymer films: A case study on films of natively unfolded nucleoporins. ACS Nano 14 (8), pp. 9938 - 9952 (2020)

MPG.PuRe

16.

Journal Article

Serres, M. P.; Samwer, M.; Truong Quang, B. A.; Lavoie, G.; Perera, U.; Görlich, D.; Charras, G.; Petronczki, M.; Roux, P. P.; Paluch, E. K.: F-actin interactome reveals vimentin as a key regulator of actin organization and cell mechanics in mitosis. Developmental Cell 52 (2), pp. 210 - 222 (2020)

MPG.PuRe

ZIP

17.

Journal Article

Karabinos, A.; Schünemann, J.; Parry, D. A. D.: Promiscuous dimerization between the Caenorhabditis elegans IF proteins and a hypothesis to explain how multiple IFs persist over evolutionary time. Journal of Molecular Evolution 87 (7-8), pp. 221 - 230 (2019)

MPG.PuRe

18.

Journal Article

Pump, W. C.; Schulz, R.; Huyton, T.; Kunze-Schumacher, H.; Martens, J.; Ho, G. G. T.; Blasczyk, R.; Bade-Doeding, C.: Releasing the concept of HLA-allele specific peptide anchors in viral infections: A non-canonical naturally presented human cytomegalovirus-derived HLA-A*24:02 restricted peptide drives exquisite immunogenicity. HLA: Immune Response Genetics 94 (1), pp. 25 - 38 (2019)

MPG.PuRe

19.

Journal Article

Aksu, M.; Trakhanov, S.; Vera Rodriguez, A.; Görlich, D.: Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. Journal of Cell Biology 218 (6), pp. 1839 - 1852 (2019)

MPG.PuRe

20.

Journal Article

Vera Rodriguez, A.; Frey, S.; Görlich, D.: Engineered SUMO/protease system identifies Pdr6 as a bidirectional nuclear transport receptor. The Journal of Cell Biology 218 (6), pp. 2006 - 2020 (2019)

MPG.PuRe

21.

Journal Article

Ho, G. G. T.; Heinen, F. J.; Huyton, T.; Blasczy, R.; Bade-Döding, C.: HLA-F*01:01 presents peptides with N-terminal flexibility and a preferred length of 16 residues. Immunogenetics 51 (5-6), pp. 353 - 360 (2019)

MPG.PuRe

22.

Journal Article

Pump, W. C.; Kraemer, T.; Huyton, T.; Hò, G. G. T.; Blasczyk, R.; Bade-Doeding, C.: Between innate and adaptive immune responses: NKG2A, NKG2C, and CD8⁺ T cell recognition of HLA-E restricted self-peptides acquired in the absence of HLA-Ia. International Journal of Molecular Sciences 20 (6), 1454 (2019)

MPG.PuRe

23.

Journal Article

Mandad, S.; Rahman, R. U.; Centeno, T. P.; Vidal, R. O.; Wildhagen, H.; Rammner, B.; Keihani, S.; Opazo, F.; Urban, I.; Ischebeck, T. et al.; Kirli, K.; Benito, E.; Fischer, A.; Yousefi, R. Y.; Dennerlein, S.; Rehling, P.; Feussner, I.; Urlaub, H.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.: The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Scientific Reports 8, 16913 (2018)

MPG.PuRe

24.

Journal Article

Simper, G. S.; Ho, G. G. T.; Celik, A. A.; Huyton, T.; Kuhn, J.; Kunze-Schumacher, H.; Blasczyk, R.; Bade-Döding, C.: Carbamazepine-mediated adverse drug reactions: CBZ-10,11-epoxide but not carbamazepine induces the alteration of peptides presented by HLA-B*15:02. Journal of Immunology Research 2018, 5086503 (2018)

MPG.PuRe

25.

Journal Article

Aksu, M.; Pleiner, T.; Karaca, S.; Kappert, C.; Dehne, H. J.; Seibel, K.; Urlaub, H.; Bohnsack, M. T.; Görlich, D.: Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 217 (7), pp. 2329 - 2340 (2018)

MPG.PuRe

26.

Journal Article

Frey, S.; Rees, R.; Schünemann, J.; Ng, S. C.; Fünfgeld, K.; Huyton, T.; Görlich, D.: Surface properties determining passage rates of proteins through nuclear pores. Cell 174 (1), pp. 202 - 217 (2018)

MPG.PuRe

27.

Journal Article

Alexeeva, M.; Guragain, P.; Tesfahun, A. N.; Tomkuviene, M.; Arshad, A.; Gerasimaite, R.; Rugenaite, A.; Urbanaviciute, G.; Bjoras, M.; Laerdahl, J. K. et al.; Klungland, A.; Klimasauskas, S.; Bjelland, S.: Excision of the doubly methylated base N-4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins. Philosophical Transactions of the Royal Society B: Biological Sciences 373 (1748), 20170337 (2018)

MPG.PuRe

28.

Journal Article

Celik, A. A.; Simper, G. S.; Huyton, T.; Blasczyk, R.; Bade-Döding, C.: HLA-G mediated immune regulation is impaired by a single amino acid exchange in the alpha 2 domain. Human Immunology 79 (6), pp. 453 - 462 (2018)

MPG.PuRe

29.

Journal Article

Ananth, A.; Genua, M.; Aissaoui, N.; Diaz, L.; Eisele, N. B.; Frey, S.; Dekker, C.; Richter, R. P.; Görlich, D.: Reversible immobilization of proteins in sensors and solid-state nanopores. Small 14 (18), 1703357 (2018)

MPG.PuRe

30.

Journal Article

Bucevicius, J.; Lukinavicius, G.; Gerasimaite, R.: The use of Hoechst dyes for DNA staining and beyond. Chemosensors 6 (2), 18 (2018)

MPG.PuRe

31.

Journal Article

Pleiner, T.; Bates, M.; Görlich, D.: A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. Journal of Cell Biology 217 (3), pp. 1143 - 1154 (2018)

MPG.PuRe

32.

Journal Article

Ananth, A. N.; Mishra, A.; Frey, S.; Dwarkasing, A.; Versloot, R.; van der Giessen, E.; Görlich, D.; Onck, P.; Dekker, C.: Spatial structure of disordered proteins dictates conductance and selectivity in Nuclear Pore Complex mimics. eLife 7, e31510 (2018)

MPG.PuRe

33.

Journal Article

Karabinos, A.; Schünemann, J.; Parry, D. A. D.: Assembly studies of six intestinal intermediate filament (IF) proteins B2, C1, C2, D1, D2, and E1 in the nematode C-elegans. Cytoskeleton 74 (3), pp. 107 - 113 (2017)

MPG.PuRe

34.

Journal Article

Göttfert, F.; Pleiner, T.; Heine, J.; Westphal, V.; Görlich, D.; Sahl, S. J.; Hell, S. W.: Strong signal increase in STED fluorescence microscopy by imaging regions of subdiffraction extent. Proceedings of the National Academy of Sciences of the United States of America 114 (9), pp. 2125 - 2130 (2017)

MPG.PuRe

35.

Journal Article

Warda, A. S.; Freytag, B.; Haag, S.; Sloan, K. E.; Görlich, D.; Bohnsack, M.: Effects of the Bowen-Conradi syndrome mutation in EMG1 on its nuclear import, stability and nucleolar recruitment. Human Molecular Genetics 25 (24), pp. 5353 - 5364 (2016)

MPG.PuRe

ZIP

36.

Journal Article

Seehusen, F.; Kiel, K.; Jottini, S.; Wohlsein, P.; Habierski, H.; Seibel, K.; Vogel, T.; Urlaub, H.; Kollmar, M.; Baumgärtner, W. et al.; Teichmann, U.: Axonopathy in the central nervous system is the hallmark of mice with a novel intragenic null mutation of dystonin. Genetics 204 (1), pp. 191 - 203 (2016)

MPG.PuRe

37.

Journal Article

Kühn, J.; Wong, L. E.; Pirkuliyeva, S.; Schulz, K.; Schwiegk, C.; Fünfgeld, K.; Keppler, S.; Batista, F. D.; Urlaub, H.; Habeck, M. et al.; Becker, S.; Griesinger, C.; Wienands, J.: The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation. Science Signaling 9 (434), ra66 (2016)

MPG.PuRe

38.

Journal Article

Aksu, M.; Trakhanov, S.; Görlich, D.: Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A. Nature Communications 7, 11952 (2016)

MPG.PuRe

39.

Journal Article

Zahn, R.; Osmanovic, D.; Ehret, S.; Callis, C. A.; Frey, S.; Stewart, M.; You, C. J.; Görlich, D.; Hoogenboom, B. W.; Richter, R. P.: A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies. eLife 5, e14119 (2016)

MPG.PuRe

40.

Journal Article

Schmidt, H. B.; Görlich, D.: Transport selectivity of nuclear pores, phase separation, and membraneless organelles. Trends in Biochemical Sciences 41 (1), pp. 46 - 61 (2016)

MPG.PuRe

41.

Journal Article

Kirli, K.; Karaca, S.; Dehne, H. J.; Samwer, M.; Pan, K. T.; Lenz, C.; Urlaub, H.; Görlich, D.: A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. eLife 4, e11466 (2015)

MPG.PuRe

42.

Journal Article

Pleiner, T.; Bates, M.; Trakhanov, S.; Lee, C. T.; Schliep, J. E.; Chug, H.; Böhning, M.; Stark, H.; Urlaub, H.; Görlich, D.: Nanobodies: Site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. eLife 4, e11349 (2015)

MPG.PuRe

43.

Journal Article

Chug, H.; Trakhanov, S.; Hülsmann, B. B.; Pleiner, T.; Görlich, D.: Crystal structure of the metazoan Nup62•Nup58•Nup54 nucleoporin complex. Science 350 (6256), pp. 106 - 110 (2015)

MPG.PuRe

44.

Journal Article

Frey, S.; Görlich, D.: The Xenopus laevis Atg4B protease: Insights into substrate recognition and application for tag removal from proteins expressed in pro- and eukaryotic hosts. PLOS One 10 (4), e0125099 (2015)

MPG.PuRe

ZIP

45.

Journal Article

Schmidt, H. B.; Görlich, D.: Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity. eLife 4, e04251 (2015)

MPG.PuRe

46.

Journal Article

Migliorini, E.; Thakar, D.; Sadir, R.; Pleiner, T.; Baleux, F.; Lortat-Jacob, H.; Coche-Guerente, L.; Richter, R. P.: Well-defined biomimetic surfaces to characterize glycosaminoglycan-mediated interactions on the molecular, supramolecular and cellular levels. Biomaterials 35 (32), pp. 8903 - 8915 (2014)

MPG.PuRe

47.

Journal Article

Hattangadi, S. M.; Martinez-Morilla, S.; Patterson, H. C.; Shi, J.; Burke, K.; Avila-Figueroa, A.; Venkatesan, S.; Wang, J.; Paulsen, K.; Görlich, D. et al.; Murata-Hori, M.; Lodish, H. F.: Histones to the cytosol: Exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood 124 (12), pp. 1931 - 1940 (2014)

MPG.PuRe

48.

Journal Article

Karabinos, A.; Schünemann, J.: Unusual ultrastructures of the Branchiostoma IF protein C2 containing heptads in the tail. Protoplasma 251 (4), pp. 985 - 988 (2014)

MPG.PuRe

49.

Journal Article

Frey, S.; Görlich, D.: A new set of highly efficient, tag-cleaving proteases for purifying recombinant proteins. Journal of Chromatography A 1337, pp. 95 - 105 (2014)

MPG.PuRe

50.

Journal Article

Frey, S.; Görlich, D.: Purification of protein complexes of defined subunit stoichiometry using a set of orthogonal, tag-cleaving proteases. Journal of Chromatography A 1337, pp. 106 - 115 (2014)

MPG.PuRe

51.

Journal Article

Eisele, N. B.; Labokha, A.; Frey, S.; Görlich, D.; Richter , R. P.: Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks - Implications for nuclear pore permeability. Biophysical Journal 105 (8), pp. 1860 - 1870 (2013)

MPG.PuRe

52.

Journal Article

Samwer, M.; Dehne, H. J.; Spira, F.; Kollmar, M.; Gerlich, D.; Urlaub, H.; Görlich, D.: The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO Journal 32 (13), pp. 1886 - 1902 (2013)

MPG.PuRe

53.

Journal Article

Aggarwal, S.; Snaidero, N.; Pähler, G.; Frey, S.; Sanchez, P.; Zweckstetter, M.; Janshoff, A.; Schneider, A.; Weil, M. T.; Schaap, I. A. T. et al.; Görlich, D.; Simons, M.: Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 11 (6), e1001577 (2013)

MPG.PuRe

54.

Journal Article

Labokha, A.; Gradmann, S.; Frey, S.; Hülsmann, B. B.; Urlaub, H.; Baldus, M.; Görlich, D.: Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO Journal 32 (2), pp. 204 - 218 (2013)

MPG.PuRe

55.

Journal Article

Karabinos, A.; Schünemann, J.; Parry, D. A. D.: A rod domain sequence in segment 1B triggers dimerisation of the two small Branchiostoma IF proteins B2 and A3. European Journal of Cell Biology 91 (10), pp. 800 - 808 (2012)

MPG.PuRe

56.

Journal Article

Hülsmann, B. B.; Labokha, A.; Görlich, D.: The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell 150 (4), pp. 738 - 751 (2012)

MPG.PuRe

57.

Journal Article

Petri, M.; Frey, S.; Menzel, A.; Görlich, D.; Techert, S.: Structural characterization of nanoscale meshworks within a nucleoporin FG hydrogel. Biomacromolecules 13 (6), pp. 1882 - 1889 (2012)

MPG.PuRe

58.

Journal Article

Eisele, N. B.; Andersson, F. I.; Frey, S.; Richter, R. P.: Viscoelasticity of thin biomolecular films: A case study on nucleoporin phenylalanine-glycine repeats grafted to a histidine- tag capturing QCM-D sensor. Biomacromolecules 13 (8), pp. 2322 - 2332 (2012)

MPG.PuRe

59.

Journal Article

Aggarwal, S.; Yurlova, L.; Snaidero, N.; Reetz, C.; Frey, S.; Zimmermann, J.; Pahler, G.; Janshoff, A.; Friedrichs, J.; Mueller, D. J. et al.; Goebel, C.; Simons, M.: A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets. Developmental Cell 21 (3), pp. 445 - 456 (2011)

MPG.PuRe

60.

Journal Article

Güttler, T.; Görlich, D.: Ran-dependent nuclear export mediators: A structural perspective. EMBO Journal 30 (17), pp. 3457 - 3474 (2011)

MPG.PuRe

61.

Journal Article

Madl, T.; Güttler, T.; Görlich, D.; Sattler, M.: Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements. Angewandte Chemie International Edition 50 (17), pp. 3993 - 3997 (2011)

MPG.PuRe

62.

Journal Article

Güttler, T.; Madl, T.; Neumann, P.; Deichsel, D.; Lorenzo, C.; Monecke, T.; Ficner, R.; Sattler, M.; Görlich, D.: NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nature Structural and Molecular Biology 17 (11), pp. 1367 - 1376 (2010)

MPG.PuRe

63.

Journal Article

Krull, S.; Dörries, J.; Boysen, B.; Reidenbach, S.; Magnius, L.; Norder, H.; Thyberg, J.; Cordes, V. C.: Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion. EMBO Journal 29 (10), pp. 1659 - 1673 (2010)

MPG.PuRe

64.

Journal Article

Eisele, N. B.; Frey, S.; Piehler, J.; Görlich, D.; Richter, R. P.: Ultrathin nucleoporin FG repeat films and their interaction with nuclear transport receptors. EMBO Reports 11 (5), pp. 366 - 372 (2010)

MPG.PuRe

65.

Journal Article

Ader, C.; Frey, S.; Maas, W.; Schmidt, H. B.; Görlich, D.; Baldus, M.: Amyloid-like interactions within nucleoporin FG hydrogels. Proceedings of the National Academy of Sciences of the United States of America 107 (14), pp. 6281 - 6285 (2010)

MPG.PuRe

66.

Journal Article

Chachami, G.; Paraskeva, E.; Mingot, J. M.; Braliou, G. G.; Görlich, D.; Simons, G.: Transport of hypoxia-inducible factor HIF-1α into the nucleus involves importins 4 and 7. Biochemical and Biophysical Research Communications 390 (2), pp. 235 - 240 (2009)

MPG.PuRe

67.

Journal Article

Mohr, D.; Frey, S.; Fischer, T.; Güttler, T.; Görlich, D.: Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO Journal 28, pp. 2541 - 2553 (2009)

MPG.PuRe

68.

Journal Article

Frey, S.; Görlich, D.: FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO Journal 28, pp. 2554 - 2567 (2009)

MPG.PuRe

69.

Journal Article

Monecke, T.; Güttler, T.; Neumann, P.; Dickmanns, A.; Görlich, D.; Ficner, R.: Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Science 324 (5930), pp. 1087 - 1091 (2009)

MPG.PuRe

70.

Journal Article

Gontan, C.; Güttler, T.; Engelen, E.; Demmers, J.; Fornerod, M.; Grosveld, F.; Tibboel, D.; Görlich, D.; Poot, A.; Rottier, R.: Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. Journal of Cell Biology 185 (1), pp. 27 - 34 (2009)

MPG.PuRe

71.

Journal Article

Weidenfeld, I.; Gossen, M.; Löw, R.; Kentner, D.; Berger, S.; Görlich, D.; Bartsch, D.; Bujard, H.; Schönig, K.: Inducible expression of coding and inhibitory RNAs from retargetable genomic loci. Nucleic Acids Research 37 (7), e50 (2009)

MPG.PuRe

72.

Journal Article

Frey, S.; Görlich, D.: A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes. Cell 130 (3), pp. 512 - 523 (2007)

MPG.PuRe

73.

Journal Article

Frey, S.; Richter, R. P.; Görlich, D.: FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science 314 (5800), pp. 815 - 817 (2006)

MPG.PuRe

74.

Journal Article

Stavru, F.; Hülsmann, B. B.; Spang, A.; Hartmann, E.; Cordes, V. C.; Görlich, D.: NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes. Journal of Cell Biology 173 (4), pp. 509 - 519 (2006)

MPG.PuRe

75.

Journal Article

Stavru, F.; Nautrup-Pedersen, G.; Cordes, V. C.; Görlich, D.: Nuclear pore complex assembly and maintenance in POM121-and gp210-deficient cells. Journal of Cell Biology 173 (4), pp. 477 - 483 (2006)

MPG.PuRe

76.

Journal Article

Bohnsack, M. T.; Stüven, T.; Kuhn, C.; Cordes, V. C.; Görlich, D.: A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes. Nature Cell Biology 8 (3), pp. 257 - 263 (2006)

MPG.PuRe

77.

Journal Article

Ribbeck, K.; Groen, A. C.; Santarella, R.; Bohnsack, M. T.; Raemaekers, T.; Köcher, T.; Gentzel, M.; Görlich, D.; Wilm, M.; Carmeliet, G. et al.; Mitchison, T. J.; Ellenberg, J.; Hoenger, A.; Mattaj, I. W.: NuSAP, a mitotic RanGTP target that stabilizes and crosslinks microtubules. Molecular Biology of the Cell 17, pp. 2646 - 2660 (2006)

MPG.PuRe

78.

Journal Article

Hantschel, O.; Wiesner, S.; Güttler, T.; Mackereth, C. D.; Remsing Rix, L. L.; Mikes, Z.; Dehne, J.; Görlich, D.; Sattler, M.; Superti-Furga, G.: Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl. Molecular Cell 19 (4), pp. 461 - 473 (2005)

MPG.PuRe

79.

Journal Article

Mingot, J.; Bohnsack, M. T.; Jäkle, U.; Görlich, D.: Exportin 7 defines a novel general nuclear export pathway. The EMBO Journal 23 (16), pp. 3227 - 3236 (2004)

MPG.PuRe

80.

Journal Article

Bohnsack, M. T.; Czaplinski, K.; Görlich, D.: Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10 (2), pp. 185 - 191 (2004)

MPG.PuRe

81.

Journal Article

Stüven, T.; Hartmann, E.; Görlich, D.: Exportin 6: a novel nuclear export receptor that is specific for profilin·actin complexes. The EMBO Journal 22 (21), pp. 5928 - 5940 (2003)

MPG.PuRe

82.

Journal Article

Fassati, A.; Görlich, D.; Harrison, I.; Zaytseva, I.; Mingot, J. M.: Nuclear import of HIV‐1 intracellular reverse transcription complexes is mediated by importin 7. The EMBO Journal 22 (14), pp. 3675 - 3685 (2003)

MPG.PuRe

83.

Journal Article

Görlich, D.; Seewald, M. J.; Ribbeck, K.: Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation. The EMBO Journal 22 (5), pp. 1088 - 1100 (2003)

MPG.PuRe

84.

Journal Article

Bohnsack, M. T.; Regener, K.; Schwappach, B.; Saffrich, R.; Paraskeva, E.; Hartmann, E.; Görlich, D.: Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. The EMBO Journal 21 (22), pp. 6205 - 6215 (2002)

MPG.PuRe

85.

Journal Article

Köhler, M.; Görlich, D.; Hartmann, E.; Franke, J.: Adenoviral E1A protein nuclear import is preferentially mediated by importin α3 in vitro. Virology 289 (2), pp. 186 - 191 (2001)

MPG.PuRe

86.

Journal Article

Dean, K. A.; von Ahsen, O.; Görlich, D.; Fried, H. M.: Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin. Journal of Cell Science 114 (19), pp. 3479 - 3485 (2001)

MPG.PuRe

87.

Journal Article

Mingot, J.; Kostka, S.; Kraft, R.; Hartmann, E.; Görlich, D.: Importin 13: a novel mediator of nuclear import and export. The EMBO Journal 20 (14), pp. 3685 - 3694 (2001)

MPG.PuRe

88.

Journal Article

Ribbeck, K.; Görlich, D.: The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion. The EMBO Journal 21 (11), pp. 2664 - 2671 (2001)

MPG.PuRe

89.

Journal Article

Ferrando-May, E.; Cordes, V.; Biller-Ckovric, I.; Mirkovic, J.; Görlich, D.; Nicotera, P.: Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis. Cell Death and Differentiation 8 (5), pp. 495 - 505 (2001)

MPG.PuRe

90.

Journal Article

Ribbeck, K.; Görlich, D.: Kinetic analysis of translocation through nuclear pore complexes. The EMBO Journal 20 (6), pp. 1320 - 1330 (2001)

MPG.PuRe

91.

Journal Article

Jäkel, S.; Mingot, J.; Schwarzmaier, P.; Hartmann, E.; Görlich, D.: Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. The EMBO Journal 21 (3), pp. 377 - 386 (2001)

MPG.PuRe

92.

Journal Article

Jäkel, S.; Mingot, J.; Schwarzmaier, P.; Hartmann, E.; Görlich, D.: Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. The EMBO Journal 21 (3), pp. 377 - 386 (2001)

MPG.PuRe

93.

Journal Article

Kutay, U.; Hartmann, E.; Treichel, N.; Calado, A.; Carmo-Fonseca, M.; Prehn, S.; Kraft, R.; Görlich, D.; Bischoff, F. R.: Identification of Two novel RanGTP-binding proteins belonging to the importin β superfamily. The Journal of Biological Chemistry 275 (51), pp. 40163 - 40168 (2000)

MPG.PuRe

94.

Journal Article

Lippai, M.; Tirián, L.; Boros, I.; Mihály, I.; Erdélyi, M.; Belecz, I.; Máthé, E.; Pósfai, J.; Nagy, A.; Udvardy, A. et al.; Paraskeva, E.; Görlich, D.; Szabad, J.: The Ketel gene encodes a Drosophila homologue of importin-β. Genetics 156 (4), pp. 1889 - 1900 (2000)

MPG.PuRe

95.

Journal Article

Villa Braslavsky, C. I.; Nowak, C.; Görlich, D.; Wittinghofer, A.; Kuhlmann, J.: Different structural and kinetic requirements for the interaction of Ran with the Ran-binding domains from RanBP2 and importin-β. Biochemistry 39 (38), pp. 11629 - 11639 (2000)

MPG.PuRe

96.

Journal Article

Lipowsky, G.; Bischoff, F. R.; Schwarzmaier, P.; Kraft, R.; Hartmann, E.; Kutay, U.; Görlich, D.: Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes. The EMBO Journal 19 (16), pp. 4362 - 4371 (2000)

MPG.PuRe

97.

Journal Article

Bannister, A. J.; Miska, E. A.; Görlich, D.; Kouzarides, T.: Acetylation of importin-α nuclear import factors by CBP/p300. Current Biology 10 (8), pp. 467 - 470 (2000)

MPG.PuRe

98.

Journal Article

Bachi, A.; Braun, I. C.; Rodrigues, J. P.; Panté, N.; Ribbeck, K.; von Kobbe, C.; Kutay, U.; Wilm, M.; Görlich, D.; Carmo-Fonseca, M. et al.; Itzaurralde, E.: The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA 6 (1), pp. 136 - 158 (2000)

MPG.PuRe

99.

Journal Article

Görlich, D.; Kutay, U.: Transport between the cell nucleus and the cytoplasm. Annual Review of Cell and Developmental Biology 15, pp. 607 - 660 (1999)

MPG.PuRe