Publications

Ng, S. C.; Görlich, D.: A simple thermodynamic description of phase separation of Nup98 FG domains. Nature Communications 13, 6172 (2022)

Huyton, T.; Jaiswal, M.; Taxer, W.; Fischer, M.; Görlich, D.: Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins. Scientific Reports 12, 16430 (2022)

Modepalli, S.; Martinez-Morilla, S.; Venkatesan , S.; Fasano, J.; Paulsen, K.; Görlich, D.; Hattangadi, S.; Kupfer, G. M.: An In Vivo Model for Elucidating the Role of an Erythroid-Specific Isoform of Nuclear Export Protein Exportin 7 (Xpo7) in Murine Erythropoiesis. Experimental Hematology 114, pp. 22 - 32 (2022)

Blaurock, C.; Breithaupt, A.; Weber, S.; Wylezich, C.; Keller, M.; Mohl, B.-P.; Görlich, D.; Groschup, M. H.; Sadeghi, B.; Höper, D. et al.; Mettenleiter, T. C.; Balkema-Buschmann, A.: Compellingly high SARS-CoV-2 susceptibility of Golden Syrian hamsters suggests multiple zoonotic infections of pet hamsters during the COVID-19 pandemic. Scientific Reports 12, 15069 (2022)

Gunkel, P.; Cordes, V. C.: ZC3HC1 is a structural element of the nuclear basket effecting interlinkage of TPR polypeptides. Molecular Biology of the Cell 33 (9), ar82 (2022)

Stegmann, K. M.; Dickmanns, A.; Heinen, N.; Blaurock, C.; Karrasch, T.; Breithaupt, A.; Klopfleisch, R.; Uhlig, N.; Eberlein, V.; Issmail, L. et al.; Herrmann, S. T.; Schreieck, A.; Peelen, E.; Kohlhof, H.; Sadeghi, B.; Riek, A.; Speakman, J. R.; Groß, U.; Görlich, D.; Vitt, D.; Müller, T.; Grunwald, T.; Pfaender, S.; Balkema-Buschmann, A.; Dobbelstein, M.: Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication. iScience 25 (5), 104293 (2022)

Najbauer, E. E.; Ng, S. C.; Griesinger, C.; Görlich, D.; Andreas, L. B.: Atomic resolution dynamics of cohesive interactions in phase-separated Nup98 FG domains. Nature Communications 13, 1494 (2022)

García-García, M.; Sánchez-Perales, S.; Jarabo, P.; Calvo, E.; Huyton, T.; Fu, L.; Ng, S. C.; Sotodosos-Alonso, L.; Vázquez, J.; Casas-Tintó, S. et al.; Görlich, D.; Echarri, A.; Del Pozo, M. A.: Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP. Nature Communications 13, 1174 (2022)

Güttler, T.; Dobbelstein, M.; Görlich, D.: Therapeutische Nanobodies gegen SARS-CoV-2. Biospektrum 28, pp. 39 - 42 (2022)

Ng, S. C.; Biswas, A.; Huyton, T.; Schünemann, J.; Reber, S.; Görlich, D.: Barrier-properties of Nup98 FG phases ruled by FG motif identity and inter-FG spacer length. bioRxiv (2022)

Gunkel, P.; Iino, H.; Krull, S.; Cordes, V.: Nuclear basket protein ZC3HC1 and its yeast homolog Pml39p feature an evolutionary conserved bimodular construction essential for initial binding to NPC-anchored homologs of scaffold protein TPR. bioRxiv (2022)