Publications

ZIP

52.

Journal Article

Schmidt, H. B.; Görlich, D.: Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity. eLife 4, e04251 (2015)

MPG.PuRe

53.

Journal Article

Migliorini, E.; Thakar, D.; Sadir, R.; Pleiner, T.; Baleux, F.; Lortat-Jacob, H.; Coche-Guerente, L.; Richter, R. P.: Well-defined biomimetic surfaces to characterize glycosaminoglycan-mediated interactions on the molecular, supramolecular and cellular levels. Biomaterials 35 (32), pp. 8903 - 8915 (2014)

MPG.PuRe

54.

Journal Article

Hattangadi, S. M.; Martinez-Morilla, S.; Patterson, H. C.; Shi, J.; Burke, K.; Avila-Figueroa, A.; Venkatesan, S.; Wang, J.; Paulsen, K.; Görlich, D. et al.; Murata-Hori, M.; Lodish, H. F.: Histones to the cytosol: Exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood 124 (12), pp. 1931 - 1940 (2014)

MPG.PuRe

55.

Journal Article

Karabinos, A.; Schünemann, J.: Unusual ultrastructures of the Branchiostoma IF protein C2 containing heptads in the tail. Protoplasma 251 (4), pp. 985 - 988 (2014)

MPG.PuRe

56.

Journal Article

Frey, S.; Görlich, D.: A new set of highly efficient, tag-cleaving proteases for purifying recombinant proteins. Journal of Chromatography A 1337, pp. 95 - 105 (2014)

MPG.PuRe

57.

Journal Article

Frey, S.; Görlich, D.: Purification of protein complexes of defined subunit stoichiometry using a set of orthogonal, tag-cleaving proteases. Journal of Chromatography A 1337, pp. 106 - 115 (2014)

MPG.PuRe

58.

Journal Article

Eisele, N. B.; Labokha, A.; Frey, S.; Görlich, D.; Richter , R. P.: Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks - Implications for nuclear pore permeability. Biophysical Journal 105 (8), pp. 1860 - 1870 (2013)

MPG.PuRe

59.

Journal Article

Samwer, M.; Dehne, H. J.; Spira, F.; Kollmar, M.; Gerlich, D.; Urlaub, H.; Görlich, D.: The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO Journal 32 (13), pp. 1886 - 1902 (2013)

MPG.PuRe

60.

Journal Article

Aggarwal, S.; Snaidero, N.; Pähler, G.; Frey, S.; Sanchez, P.; Zweckstetter, M.; Janshoff, A.; Schneider, A.; Weil, M. T.; Schaap, I. A. T. et al.; Görlich, D.; Simons, M.: Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 11 (6), e1001577 (2013)

MPG.PuRe

61.

Journal Article

Labokha, A.; Gradmann, S.; Frey, S.; Hülsmann, B. B.; Urlaub, H.; Baldus, M.; Görlich, D.: Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO Journal 32 (2), pp. 204 - 218 (2013)

MPG.PuRe

62.

Journal Article

Karabinos, A.; Schünemann, J.; Parry, D. A. D.: A rod domain sequence in segment 1B triggers dimerisation of the two small Branchiostoma IF proteins B2 and A3. European Journal of Cell Biology 91 (10), pp. 800 - 808 (2012)

MPG.PuRe

63.

Journal Article

Hülsmann, B. B.; Labokha, A.; Görlich, D.: The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell 150 (4), pp. 738 - 751 (2012)

MPG.PuRe

64.

Journal Article

Petri, M.; Frey, S.; Menzel, A.; Görlich, D.; Techert, S.: Structural characterization of nanoscale meshworks within a nucleoporin FG hydrogel. Biomacromolecules 13 (6), pp. 1882 - 1889 (2012)

MPG.PuRe

65.

Journal Article

Eisele, N. B.; Andersson, F. I.; Frey, S.; Richter, R. P.: Viscoelasticity of thin biomolecular films: A case study on nucleoporin phenylalanine-glycine repeats grafted to a histidine- tag capturing QCM-D sensor. Biomacromolecules 13 (8), pp. 2322 - 2332 (2012)

MPG.PuRe

66.

Journal Article

Aggarwal, S.; Yurlova, L.; Snaidero, N.; Reetz, C.; Frey, S.; Zimmermann, J.; Pahler, G.; Janshoff, A.; Friedrichs, J.; Mueller, D. J. et al.; Goebel, C.; Simons, M.: A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets. Developmental Cell 21 (3), pp. 445 - 456 (2011)

MPG.PuRe

67.

Journal Article

Güttler, T.; Görlich, D.: Ran-dependent nuclear export mediators: A structural perspective. EMBO Journal 30 (17), pp. 3457 - 3474 (2011)

MPG.PuRe

68.

Journal Article

Madl, T.; Güttler, T.; Görlich, D.; Sattler, M.: Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements. Angewandte Chemie International Edition 50 (17), pp. 3993 - 3997 (2011)

MPG.PuRe

69.

Journal Article

Güttler, T.; Madl, T.; Neumann, P.; Deichsel, D.; Lorenzo, C.; Monecke, T.; Ficner, R.; Sattler, M.; Görlich, D.: NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nature Structural and Molecular Biology 17 (11), pp. 1367 - 1376 (2010)

MPG.PuRe

70.

Journal Article

Krull, S.; Dörries, J.; Boysen, B.; Reidenbach, S.; Magnius, L.; Norder, H.; Thyberg, J.; Cordes, V. C.: Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion. EMBO Journal 29 (10), pp. 1659 - 1673 (2010)

MPG.PuRe

71.

Journal Article

Eisele, N. B.; Frey, S.; Piehler, J.; Görlich, D.; Richter, R. P.: Ultrathin nucleoporin FG repeat films and their interaction with nuclear transport receptors. EMBO Reports 11 (5), pp. 366 - 372 (2010)

MPG.PuRe

72.

Journal Article

Ader, C.; Frey, S.; Maas, W.; Schmidt, H. B.; Görlich, D.; Baldus, M.: Amyloid-like interactions within nucleoporin FG hydrogels. Proceedings of the National Academy of Sciences of the United States of America 107 (14), pp. 6281 - 6285 (2010)

MPG.PuRe

73.

Journal Article

Chachami, G.; Paraskeva, E.; Mingot, J. M.; Braliou, G. G.; Görlich, D.; Simons, G.: Transport of hypoxia-inducible factor HIF-1α into the nucleus involves importins 4 and 7. Biochemical and Biophysical Research Communications 390 (2), pp. 235 - 240 (2009)

MPG.PuRe

74.

Journal Article

Mohr, D.; Frey, S.; Fischer, T.; Güttler, T.; Görlich, D.: Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO Journal 28, pp. 2541 - 2553 (2009)

MPG.PuRe

75.

Journal Article

Frey, S.; Görlich, D.: FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO Journal 28, pp. 2554 - 2567 (2009)

MPG.PuRe

76.

Journal Article

Monecke, T.; Güttler, T.; Neumann, P.; Dickmanns, A.; Görlich, D.; Ficner, R.: Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Science 324 (5930), pp. 1087 - 1091 (2009)

MPG.PuRe

77.

Journal Article

Gontan, C.; Güttler, T.; Engelen, E.; Demmers, J.; Fornerod, M.; Grosveld, F.; Tibboel, D.; Görlich, D.; Poot, A.; Rottier, R.: Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. Journal of Cell Biology 185 (1), pp. 27 - 34 (2009)

MPG.PuRe

78.

Journal Article

Weidenfeld, I.; Gossen, M.; Löw, R.; Kentner, D.; Berger, S.; Görlich, D.; Bartsch, D.; Bujard, H.; Schönig, K.: Inducible expression of coding and inhibitory RNAs from retargetable genomic loci. Nucleic Acids Research 37 (7), e50 (2009)

MPG.PuRe

79.

Journal Article

Frey, S.; Görlich, D.: A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes. Cell 130 (3), pp. 512 - 523 (2007)

MPG.PuRe

80.

Journal Article

Frey, S.; Richter, R. P.; Görlich, D.: FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science 314 (5800), pp. 815 - 817 (2006)

MPG.PuRe

81.

Journal Article

Stavru, F.; Hülsmann, B. B.; Spang, A.; Hartmann, E.; Cordes, V. C.; Görlich, D.: NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes. Journal of Cell Biology 173 (4), pp. 509 - 519 (2006)

MPG.PuRe

82.

Journal Article

Stavru, F.; Nautrup-Pedersen, G.; Cordes, V. C.; Görlich, D.: Nuclear pore complex assembly and maintenance in POM121-and gp210-deficient cells. Journal of Cell Biology 173 (4), pp. 477 - 483 (2006)

MPG.PuRe

83.

Journal Article

Bohnsack, M. T.; Stüven, T.; Kuhn, C.; Cordes, V. C.; Görlich, D.: A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes. Nature Cell Biology 8 (3), pp. 257 - 263 (2006)

MPG.PuRe

84.

Journal Article

Ribbeck, K.; Groen, A. C.; Santarella, R.; Bohnsack, M. T.; Raemaekers, T.; Köcher, T.; Gentzel, M.; Görlich, D.; Wilm, M.; Carmeliet, G. et al.; Mitchison, T. J.; Ellenberg, J.; Hoenger, A.; Mattaj, I. W.: NuSAP, a mitotic RanGTP target that stabilizes and crosslinks microtubules. Molecular Biology of the Cell 17, pp. 2646 - 2660 (2006)

MPG.PuRe

85.

Journal Article

Hantschel, O.; Wiesner, S.; Güttler, T.; Mackereth, C. D.; Remsing Rix, L. L.; Mikes, Z.; Dehne, J.; Görlich, D.; Sattler, M.; Superti-Furga, G.: Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl. Molecular Cell 19 (4), pp. 461 - 473 (2005)

MPG.PuRe

86.

Journal Article

Mingot, J.; Bohnsack, M. T.; Jäkle, U.; Görlich, D.: Exportin 7 defines a novel general nuclear export pathway. The EMBO Journal 23 (16), pp. 3227 - 3236 (2004)

MPG.PuRe

87.

Journal Article

Bohnsack, M. T.; Czaplinski, K.; Görlich, D.: Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10 (2), pp. 185 - 191 (2004)

MPG.PuRe

88.

Journal Article

Stüven, T.; Hartmann, E.; Görlich, D.: Exportin 6: a novel nuclear export receptor that is specific for profilin·actin complexes. The EMBO Journal 22 (21), pp. 5928 - 5940 (2003)

MPG.PuRe

89.

Journal Article

Fassati, A.; Görlich, D.; Harrison, I.; Zaytseva, I.; Mingot, J. M.: Nuclear import of HIV‐1 intracellular reverse transcription complexes is mediated by importin 7. The EMBO Journal 22 (14), pp. 3675 - 3685 (2003)

MPG.PuRe

90.

Journal Article

Görlich, D.; Seewald, M. J.; Ribbeck, K.: Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation. The EMBO Journal 22 (5), pp. 1088 - 1100 (2003)

MPG.PuRe

91.

Journal Article

Bohnsack, M. T.; Regener, K.; Schwappach, B.; Saffrich, R.; Paraskeva, E.; Hartmann, E.; Görlich, D.: Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. The EMBO Journal 21 (22), pp. 6205 - 6215 (2002)

MPG.PuRe

92.

Journal Article

Köhler, M.; Görlich, D.; Hartmann, E.; Franke, J.: Adenoviral E1A protein nuclear import is preferentially mediated by importin α3 in vitro. Virology 289 (2), pp. 186 - 191 (2001)

MPG.PuRe

93.

Journal Article

Dean, K. A.; von Ahsen, O.; Görlich, D.; Fried, H. M.: Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin. Journal of Cell Science 114 (19), pp. 3479 - 3485 (2001)

MPG.PuRe

94.

Journal Article

Mingot, J.; Kostka, S.; Kraft, R.; Hartmann, E.; Görlich, D.: Importin 13: a novel mediator of nuclear import and export. The EMBO Journal 20 (14), pp. 3685 - 3694 (2001)

MPG.PuRe

95.

Journal Article

Ribbeck, K.; Görlich, D.: The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion. The EMBO Journal 21 (11), pp. 2664 - 2671 (2001)

MPG.PuRe

96.

Journal Article

Ferrando-May, E.; Cordes, V.; Biller-Ckovric, I.; Mirkovic, J.; Görlich, D.; Nicotera, P.: Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis. Cell Death and Differentiation 8 (5), pp. 495 - 505 (2001)

MPG.PuRe

97.

Journal Article

Ribbeck, K.; Görlich, D.: Kinetic analysis of translocation through nuclear pore complexes. The EMBO Journal 20 (6), pp. 1320 - 1330 (2001)

MPG.PuRe

98.

Journal Article

Jäkel, S.; Mingot, J.; Schwarzmaier, P.; Hartmann, E.; Görlich, D.: Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. The EMBO Journal 21 (3), pp. 377 - 386 (2001)

MPG.PuRe

99.

Journal Article

Jäkel, S.; Mingot, J.; Schwarzmaier, P.; Hartmann, E.; Görlich, D.: Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. The EMBO Journal 21 (3), pp. 377 - 386 (2001)

MPG.PuRe

100.

Journal Article

Kutay, U.; Hartmann, E.; Treichel, N.; Calado, A.; Carmo-Fonseca, M.; Prehn, S.; Kraft, R.; Görlich, D.; Bischoff, F. R.: Identification of Two novel RanGTP-binding proteins belonging to the importin β superfamily. The Journal of Biological Chemistry 275 (51), pp. 40163 - 40168 (2000)

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