Publications

152.

Journal Article

Bremmer, F.; Bohnenberger, H.; Küffer, S.; Oellerich, T.; Serve, H.; Urlaub, H.; Strauss, A.; Maatoug, Y.; Behnes, C. L.; Oing, C. et al.; Radzun, H. J.; Ströbel, P.; Balabanov, S.; Honecker, F.: Proteomic comparison of malignant human germ cell tumor cell lines. Disease Markers 2019, 8298524 (2019)

MPG.PuRe

153.

Journal Article

Yagensky, O.; Kohansal-Nodehi, M.; Gunaseelan, S.; Rabe, T.; Zafar, S.; Zerr, I.; Haertig, W.; Urlaub, H.; Chua, J.: Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 8, e47498 (2019)

MPG.PuRe

154.

Journal Article

Alsina, K. M.; Hulsurkar, M.; Brandenburg, S.; Kownatzki-Danger, D.; Lenz, C.; Urlaub, H.; Abu-Taha, I.; Kamler, M.; Chiang, D. Y.; Lahiri, S. K. et al.; Reynolds, J. O.; Quick, A. P.; Scott, L.; Word, T. A.; Gelves, M. D.; Heck, A. J. R.; Li, N.; Dobrev, D.; Lehnart, S. E.; Wehrens, X. H. T.: Loss of protein phosphatase 1 regulatory subunit PPP1R3A promotes atrial fibrillation. Circulation 140 (8), pp. 681 - 693 (2019)

MPG.PuRe

155.

Journal Article

Liess, A. K. L.; Kucerova, A.; Schweimer, K.; Yu, L.; Roumeliotis, T. I.; Diebold, M.; Dybkov, O.; Sotriffer, C.; Urlaub, H.; Choudhary, J. S. et al.; Mansfeld, J.; Lorenz, S.: Autoinhibition mechanism of the ubiquitin-conjugating enzyme UBE2S by autoubiquitination. Structure 27 (8), pp. 1195 - 1210 (2019)

MPG.PuRe

156.

Journal Article

Callegari, S.; Müller, T.; Schulz, C.; Lenz, C.; Jans, D. C.; Wissel, M.; Opazo, F.; Rizzoli, S. O.; Jakobs, S.; Urlaub, H. et al.; Rehling, P.; Deckers, M.: A MICOS-TIM22 association promotes carrier import into human mitochondria. Journal of Molecular Biology 431 (15), pp. 2835 - 2851 (2019)

MPG.PuRe

157.

Journal Article

Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10, 2885 (2019)

MPG.PuRe

158.

Journal Article

Coy-Vergara, J.; Rivera-Monroy, J.; Urlaub, H.; Lenz, C.; Schwappach, B.: A trap mutant reveals the physiological client spectrum of TRC40. Journal of Cerll Science, (in press) (2019)

MPG.PuRe

pre-print

159.

Journal Article

Chachami, G.; Stankovic-Valentin, N.; Karagiota, A.; Basagianni, A.; Pleßmann, U.; Urlaub, H.; Melchior, F.; Simos, G.: Hypoxia-induced changes in SUMO conjugation affect transcriptional regulation under low oxygen. Molecular and Cellular Proteomics 18 (6), pp. 1197 - 1209 (2019)

MPG.PuRe

160.

Journal Article

Garofalo, R.; Wohlgemuth, I.; Pearson, M.; Lenz, C.; Urlaub, H.; Rodnina, M. V.: Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 47 (6), pp. 2932 - 2945 (2019)

MPG.PuRe

161.

Journal Article

Papathanasiou, P.; Erdmann, S.; Leon-Sobrino, C.; Sharma, K.; Urlaub, H.; Garrett, R. A.; Peng, X.: Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1. RNA Biology 16 (4), pp. 557 - 565 (2019)

MPG.PuRe

162.

Journal Article

Schroeder, M. P.; Bastian, L.; Eckert, C.; Gökbuget, N.; James, A. R.; Ortiz Tanchez, J.; Schlee, C.; Isaakidis, K.; Häupl, B.; Baum, K. et al.; Lozano, O. A. M.; Kouidri, K.; Pan, K. T.; Urlaub, H.; Schwartz, S.; Burmeister, T.; von Stackelberg, A.; Hoelzer, D.; Pfeiffer, H.; Rieger, M. A.; Göllner, S.; Oellerich, T.; Horstman, M.; Schrappe, M.; Wolf, J.; Kirschner-Schwabe, R.; Brüggemann, M.; Müller-Tidow, C.; Serve, H.; Neumann, M.; Baldus, C. D.: Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures. Scientific Reports 9 (1), 4188 (2019)

MPG.PuRe

163.

Journal Article

Michels, B. E.; Mosa, M. H.; Grebbin, B. M.; Yepes, D.; Darvishi, T.; Hausmann, J.; Urlaub, H.; Zeuzem, S.; Kvasnicka, H. M.; Oellerich, T. et al.; Farin, H. F.: Human colon organoids reveal distinct physiologic and oncogenic Wnt responses. Journal of Experimental Medicine 216 (3), 704 (2019)

MPG.PuRe

164.

Journal Article

Richter, F.; Dennerlein, S.; Nikolov, M.; Jans, D. C.; Naumenko, N.; Aich, A.; MacVicar, T.; Linden, A.; Jakobs, S.; Urlaub, H. et al.; Langer, T.; Rehling, P.: ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. The Journal of Cell Biology 218 (2), 598 (2019)

MPG.PuRe

165.

Journal Article

Maier, L. K.; Stachler, A. E.; Brendel, J.; Stoll, B.; Fischer, S.; Haas, K.; Schwarz, T.; Alkhnbashi, O. S.; Sharma, K.; Urlaub, H. et al.; Backofen, R.; Gophna, U.; Marchfelder, A.: The nuts and bolts of the Haloferax CRISPR-Cas system I-B. RNA Biology 16 (4), pp. 469 - 480 (2019)

MPG.PuRe

166.

Journal Article

Masanta, W. O.; Zautner, A. E.; Lugert, R.; Bohne, W.; Gross, U.; Leha, A.; Dakna, M.; Lenz, C.: Proteome profiling by label‐free mass spectrometry reveals differentiated response of Campylobacter jejuni 81–176 to sublethal concentrations of bile acids. Proteomics 13 (3), 1800083 (2019)

MPG.PuRe

167.

Journal Article

Mishto, M.; Mansurkhodzhaev, A.; Ying, G.; Bitra, A.; Cordfunke, R. A.; Henze, S.; Paul, D.; Sidney, J.; Urlaub, H.; Neefjes, J. et al.; Sette, A.; Zajonc, D. M.; Liepe, J.: An in silico-in vitro pipeline identifying an HLA-A^*02:01⁺ KRAS G12V⁺ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 10, 2572 (2019)

MPG.PuRe

168.

Journal Article

Özcan, A.; Pausch, P.; Linden, A.; Wulf, A.; Schühle, K.; Heider, J.; Urlaub, H.; Heimerl, T.; Bange, G.; Randau, L.: Type IV CRISPR RNA processing and effector complex formation in Aromatoleum aromaticum. Nature Microbiology 4 (1), pp. 89 - 96 (2019)

MPG.PuRe

169.

Journal Article

Ramani, A.; Mariappan, A.; Gottardo, M.; Mandad, S.; Urlaub, H.; Avidor-Reiss, T.; Riparbelli, M.; Giuliano, C.; Debec, A.; Feederle, R. et al.; Gopalakrishnan, J.: Plk1/Polo phosphorylates Sas-4 at the onset of mitosis for an efficient recruitment of pericentriolar material to centrosomes. Cell Reports 25 (13), pp. 3618 - 3630 (2018)

MPG.PuRe

170.

Journal Article

Brüning, L.; Hackert, P.; Martin, R.; Gallesio, J. D.; Aquino, G. R. R.; Urlaub, H.; Sloan, K. E.; Bohnsack, M. T.: RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes. Nature Communications 9, 5383 (2018)

MPG.PuRe

171.

Journal Article

Braun, J.; Fischer, S.; Xu, Z. Z.; Dalia, S.; Ghoneim, D. H.; Gimbel, A. T.; Plessmann, U.; Urlaub, H.; Mathews, D. H.; Weigand, J. E.: Identification of new high affinity targets for Roquin based on structural conservation. Nucleic Acids Research 46 (22), pp. 12109 - 12125 (2018)

MPG.PuRe

172.

Journal Article

Mariappan, A.; Soni, K.; Schorpp, K.; Zhao, F.; Minakar, A.; Zheng, X.; Mandad, S.; Macheleidt, I.; Ramani, A.; Kubelka, T. et al.; Dawidowski, M.; Golfmann, K.; Wason, A.; Yang, C.; Simons, J.; Schmalz, H. G.; Hyman, A. A.; Aneja, R.; Ullrich, R.; Urlaub, H.; Odenthal, M.; Büttner, R.; Li, H.; Sattler, M.; Hadian, K.; Gopalakrishnan, J.: Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells. The EMBO Journal, In press (e99876) (2018)

MPG.PuRe

173.

Journal Article

Mandad, S.; Rahman, R. U.; Centeno, T. P.; Vidal, R. O.; Wildhagen, H.; Rammner, B.; Keihani, S.; Opazo, F.; Urban, I.; Ischebeck, T. et al.; Kirli, K.; Benito, E.; Fischer, A.; Yousefi, R. Y.; Dennerlein, S.; Rehling, P.; Feussner, I.; Urlaub, H.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.: The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Scientific Reports 8, 16913 (2018)

MPG.PuRe

174.

Journal Article

Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C. T.; Perez-Lara, A.; Chakraborty, P.; Hofele, R. V.; Baker, J. D.; Blair, L. J.; Biernat, J. et al.; Urlaub, H.; Mandelkow, E.; Dickey, C. A.; Zweckstetter, M.: Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 9, 4532 (2018)

MPG.PuRe

175.

Journal Article

Buskin, A.; Zhu, L.; Chichagova, V.; Basu, B.; Mozafarri Jovin, S.; Dolan, D.; Droop, A.; Collin, J.; Bronstein, R.; Mehrotra, S. et al.; Farkas, M.; Hilgen, G.; White, K.; Pan, K. T.; Treumann, A.; Hallam, D.; Bialas, K.; Chung, G.; Mellough, C.; Ding, Y.; Krasnogor, N.; Przyborski, S.; Zwolinski, S.; Al-Aama, J.; Alharthi, S.; Xu, Y.; Wheway, G.; Szymanska, K.; McKibbin, M.; Inglehearn, C. F.; Elliott, D. J.; Lindsay, S.; Ali, R. R.; Steel, D. H.; Armstrong, L.; Sernagor, E.; Urlaub, H.; Pierce, E.; Lührmann, R.; Grellscheid, S. N.; Johnson, C. A.; Lako, M.: Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications 9, 4234 (2018)

MPG.PuRe

176.

Journal Article

Fornasiero, E. F.; Mandad, S.; Wildhagen, H.; Alevra, M.; Rammner, B.; Keihani, S.; Opazo, F.; Urban, I.; Ischebeck, T.; Sakib, M. S. et al.; Fard, M. K.; Kirli, K.; Centeno, T. P.; Vidal, R. O.; Rahman, R. U.; Benito, E.; Fischer, A.; Dennerlein, S.; Rehling, P.; Feussner, I.; Bonn, S.; Simons, M.; Urlaub, H.; Rizzoli, S. O.: Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. Nature Communications 9, 4230 (2018)

MPG.PuRe

177.

Journal Article

Lavdovskaia, E.; Kolander, E.; Steube, E.; Mai, M. M.; Urlaub, H.; Richter-Dennerlein, R.: The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis. Nucleic Acids Research 46 (16), pp. 8471 - 8482 (2018)

MPG.PuRe

178.

Journal Article

Blaschke, M.; Koepp, R.; Lenz, C.; Kruppa, J.; Jung, K.; Siggelkow, H.: Crohn's disease patient serum changes protein expression in a human mesenchymal stem cell model in a linear relationship to patients' disease stage and to bone mineral density. Journal of Clinical and Translational Endocrinology 13, pp. 26 - 38 (2018)

MPG.PuRe

179.

Journal Article

Bohnenberger, H.; Kaderali, L.; Ströbel, P.; Yepes, D.; Pleßmann, U.; Dharia, N. Y.; Yao, S.; Heydt, C.; Merkelbach‐Bruse, S.; Emmert, A. et al.; Hoffmann, J.; Bodemeyer, J.; Reuter‐Jessen, K.; Lois, A. M.; Dröge, L. H.; Baumeister, P.; Walz, C.; Biggemann, L.; Walter, R.; Häupl, B.; Comoglio, F.; Pan, K. T.; Scheich, S.; Lenz, C.; Küffer, S.; Bremmer, F.; Kitz, J.; Sitte, M.; Beißbarth, T.; Hinterthaner, M.; Sebastian, M.; Lotz, J.; Schildhaus, H. U.; Wolff, H.; Danner, B. C.; Brandts, C.; Büttner, R.; Canis, M.; Stegmaier, K.; Serve, H.; Urlaub, H.; Oellerich, T.: Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis. EMBO Molecular Medicine 10 (9), e8428 (2018)

MPG.PuRe

180.

Journal Article

Vos, S. M.; Farnung, L.; Böhning, M.; Wigge, C.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), pp. 607 - 612 (2018)

MPG.PuRe

Full

181.

Journal Article

Vos, S. M.; Farnung, L.; Urlaub, H.; Cramer, P.: Structure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), pp. 601 - 606 (2018)

MPG.PuRe

182.

Journal Article

Mühlhausen, S.; Schmitt, H. D.; Pan, K. T.; Plessmann, U.; Urlaub, H.; Hurst, L. D.; Kollmar, M.: Endogenous stochastic decoding of the CUG codon by competing Ser- and Leu-tRNAs in Ascoidea asiatica. Current Biology 28 (13), pp. 2046 - 2057 (2018)

MPG.PuRe

183.

Journal Article

Aksu, M.; Pleiner, T.; Karaca, S.; Kappert, C.; Dehne, H. J.; Seibel, K.; Urlaub, H.; Bohnsack, M. T.; Görlich, D.: Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 217 (7), pp. 2329 - 2340 (2018)

MPG.PuRe

184.

Journal Article

Cyganek, L.; Tiburcy, M.; Sekeres, K.; Gerstenberg, K.; Bohnenberger, H.; Lenz, C.; Henze, S.; Stauske, M.; Salinas, G.; Zimmermann, W. H. et al.; Hasenfuss, G.; Guan, K.: Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI Insight 3 (12), e99941 (2018)

MPG.PuRe

185.

Journal Article

Johannsson, S.; Neumann, P.; Wulf, A.; Welp, L. M.; Gerber, H. D.; Krull, M.; Diederichsen, U.; Urlaub, H.; Ficner, R.: Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. Scientific Reports 8, 8880 (2018)

MPG.PuRe

186.

Journal Article

Dihazi, H.; Asif, A. R.; Beißbarth, T.; Bohrer, R.; Feussner, K.; Feussner, I.; Jahn, O.; Lenz, C.; Majcherczyk, A.; Schmidt, B. et al.; Schmitt, K.; Urlaub, H.; Valerius, O.: Integrative omics - from data to biology. Expert Review of Proteomics 15 (6), pp. 463 - 466 (2018)

MPG.PuRe

187.

Journal Article

Zaman, U.; Urlaub, H.; Abbasi, A.: Protein profiling of non-model plant Cuminum cyminum by gel-based proteomic approach. Phytochemical Analysis 29 (3), pp. 242 - 249 (2018)

MPG.PuRe

188.

Journal Article

Dickmanns, A.; Zschiedrich, C. P.; Arens, J.; Parfentev, I.; Gundlach, J.; Hofele, R.; Neumann, P.; Urlaub, H.; Görke, B.; Ficner, R. et al.; Stulke, J.: Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh in Bacillus subtilis. The Journal of Biological Chemistry 293 (16), pp. 5781 - 5792 (2018)

MPG.PuRe

189.

Journal Article

Batschkus, S.; Cingoez, G.; Urlaub, H.; Miosge, N.; Kirschneck, C.; Meyer-Marcotty, P.; Lenz, C.: A new albumin-depletion strategy improves proteomic research of gingival crevicular fluid from periodontitis patients. Clinical Oral Investigations 22 (3), pp. 1375 - 1384 (2018)

MPG.PuRe

190.

Journal Article

Rocha de Moura, T.; Mozaffari-Jovin, S.; Szabo, C. Z. K.; Schmitzova, J.; Dybkov, O.; Cretu, C.; Kachala, M.; Svergun, D.; Urlaub, H.; Lührmann, R. et al.; Pena, V.: Prp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 69 (6), pp. 979 - 992 (2018)

MPG.PuRe

191.

Journal Article

Behler, J.; Sharma, K.; Reimann, V.; Wilde, A.; Urlaub, H.; Hess, W. R.: The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nature Microbiology 3 (3), pp. 367 - 377 (2018)

MPG.PuRe

192.

Journal Article

Buddeweg, A.; Sharma, K.; Urlaub, H.; Schmitz, R. A.: sRNA41 affects ribosome binding sites within polycistronic mRNAs in Methanosarcina mazei Gö1. Molecular Microbiology 107 (5), pp. 595 - 609 (2018)

MPG.PuRe

193.

Journal Article

Sonnleitner, E.; Wulf, A.; Campagne, S.; Pei, X. Y.; Wolfinger, M. T.; Forlani, G.; Prindl, K.; Abdou, L.; Resch, A.; Allain, F. H. et al.; Luisi, B. F.; Urlaub, H.; Bläsi, U.: Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa. Nucleic Acids Research 46 (3), pp. 1470 - 1485 (2018)

MPG.PuRe

194.

Journal Article

Haselbach, D.; Komarov, I.; Agafonov, D. E.; Hartmuth, K.; Graf, B.; Dybkov, O.; Urlaub, H.; Kastner, B.; Lührmann, R.; Stark, H.: Structure and conformational dynamics of the human spliceosomal B^act complex. Cell 172 (3), pp. 454 - 464, e1-e5 (2018)

MPG.PuRe

195.

Journal Article

Fard, M. K.; van der Meer, F.; Sánchez, P.; Cantuti-Castelvetri, L.; Mandad, S.; Jäkel, S.; Fornasiero, E. F.; Schmitt, S.; Ehrlich, M.; Starost, L. et al.; Kuhlmann, T.; Sergiou, C.; Schultz, V.; Wrzos, C.; Brück, W.; Urlaub, H.; Dimou, L.; Stadelmann, C.; Simons, M.: BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. Science Translational Medicine 9 (419), eaam7816 (2017)

MPG.PuRe

196.

Journal Article

Bao, P.; Will, C. L.; Urlaub, H.; Boon, K. L.; Lührmann, R.: The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex. Genes and Development 31 (23-24), pp. 2416 - 2429 (2017)

MPG.PuRe

197.

Journal Article

Ahdash, Z.; Lau, A. M.; Byrne, R. T.; Lammens, K.; Stützer, A.; Urlaub, H.; Booth, P. J.; Reading, E.; Hopfner, K. P.; Politis, A.: Mechanistic insight into the assembly of the HerA-NurA helicase-nuclease DNA end resection complex. Nucleic Acids Research 45 (20), pp. 12025 - 12038 (2017)

MPG.PuRe

198.

Journal Article

Hillen, H. S.; Parshin, A. V.; Agaronyan, K.; Morozov, Y. I.; Graber, J. J.; Chernev, A.; Schwinghammer, K.; Urlaub, H.; Anikin, M.; Cramer, P. et al.; Temiakov, D.: Mechanism of transcription anti-termination in human mitochondria. Cell 171 (5), pp. 1082 - 1093 (2017)

MPG.PuRe

199.

Journal Article

Schilbach, S.; Hantsche, M.; Tegunov, D.; Dienemann, C.; Wigge, C.; Urlaub, H.; Cramer, P.: Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature 551 (7679), pp. 204 - 209 (2017)

MPG.PuRe

200.

Journal Article

Warda, A. S.; Kretschmer, J.; Hackert, P.; Lenz, C.; Urlaub, H.; Höbartner, C.; Sloan, K. E.; Bohnsack, M. T.: Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs. EMBO Reports 18 (11), pp. 2004 - 2014 (2017)

MPG.PuRe