Publications
Journal Article (382)
1.
Journal Article
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3. Neuron, In Press (2022)
2.
Journal Article
Database search engines and target database features impinge upon the identification of post‐translationally cis‐spliced peptides in HLA class I immunopeptidomes. Proteomics, In Press; 2100226 (2022)
3.
Journal Article
374 (6569), pp. 883 - 887 (2021)
Structural basis of Integrator-mediated transcription regulation. Science 4.
Journal Article
598 (7880), pp. 368 - 372 (2021)
Structural basis of human transcription–DNA repair coupling. Nature 5.
Journal Article
596 (7871), pp. 296 - 300 (2021)
Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature 6.
Journal Article
24 (8), pp. 1151 - 1162 (2021)
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines. Nature Neuroscience 7.
Journal Article
81 (16), pp. 3386 - 3399.e10 (2021)
Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 8.
Journal Article
93 (25), pp. 8846 - 8855 (2021)
Evaluation and optimization of high-field asymmetric waveform ion-mobility spectrometry for multiplexed quantitative site-specific N-glycoproteomics. Analytical Chemistry 9.
Journal Article
15, 643391 (2021)
Low-Expressing synucleinopathy mouse models based on oligomer-forming mutations and C-terminal truncation of α-synuclein. Frontiers in Neuroscience 10.
Journal Article
12, 3672 (2021)
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling. Nature Communications 11.
Journal Article
49 (10), pp. 5845 - 5866 (2021)
SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes. Nucleic Acids Research 12.
Journal Article
296, 100734 (2021)
The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 13.
Journal Article
593 (7859), pp. 460 - 464 (2021)
A lysine–cysteine redox switch with an NOS bridge regulates enzyme function. Nature 14.
Journal Article
206 (10), pp. 2322 - 2337 (2021)
Itk promotes the integration of TCR and CD28 costimulation through its direct substrates SLP-76 and Gads. The Journal of Immunology 15.
Journal Article
49 (6), pp. 3507 - 3523 (2021)
Methylated HNRNPK acts on RPS19 to regulate ALOX15 synthesis in erythropoiesis. Nucleic Acids Research 16.
Journal Article
12, 1830 (2021)
Translation error clusters induced by aminoglycoside antibiotics. Nature Communications 17.
Journal Article
10, e63868 (2021)
Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization. eLife 18.
Journal Article
12 (1), pp. 185 - 203 (2021)
Extracellular vesicles derived from neural progenitor cells: A preclinical evaluation for stroke treatment in mice. Translational Stroke Research 19.
Journal Article
595 (2), pp. 157 - 168 (2021)
Defining the architecture of the human TIM22 complex by chemical crosslinking. FEBS Letters 20.
Journal Article
18 (12), pp. 2466 - 2479 (2021)
Structural model of the M7G46 methyltransferase TrmB in complex with tRNA. RNA Biology 21.
Journal Article
20, 100061 (2021)
Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling. Molecular and Cellular Proteomics 22.
Journal Article
370 (6523), eabc3753 (2020)
Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science 23.
Journal Article
48 (22), pp. 12929 - 12942 (2020)
Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. Nucleic Acids Research 24.
Journal Article
19 (12), pp. 2157 - 2167 (2020)
OpenPepXL: An open-source tool for sensitive identification of cross-linked peptides in XL-MS. Molecular and Cellular Proteomics 25.
Journal Article
28 (11), pp. 1259 - 1268 (2020)
Toward increased reliability, transparency, and accessibility in cross-linking mass spectrometry. Structure 26.
Journal Article
117 (42), pp. 26318 - 26327 (2020)
Rewiring of B cell receptor signaling by Epstein–Barr virus LMP2A. Proceedings of the National Academy of Sciences of the USA 27.
Journal Article
13 (654), eaba8208 (2020)
Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. Science Signaling 28.
Journal Article
11, 5250 (2020)
Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry. Nature Communications 29.
Journal Article
80 (1), pp. 127 - 139.e6 (2020)
Structural insights into the roles of metazoan-specific splicing factors in the human step 1 spliceosome. Molecular Cell 30.
Journal Article
27 (10), pp. 2810 - 2827 (2020)
Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. Cell Death and Differentiation 31.
Journal Article
13 (647), eaaz1436 (2020)
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban. Science Signaling 32.
Journal Article
6 (30), eaba3916 (2020)
Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 33.
Journal Article
583 (7815), pp. 310 - 313 (2020)
Molecular architecture of the human 17S U2 snRNP. Nature 34.
Journal Article
463 (1), pp. 53 - 62 (2020)
The bicistronic gene würmchen encodes two essential components for epithelial development in Drosophila. Developmental Biology 35.
Journal Article
19 (7), pp. 1161 - 1178 (2020)
A Cross-linking mass spectrometry approach defines protein interactions in yeast mitochondria. Molecular and Cellular Proteomics 36.
Journal Article
27 (7), pp. 668 - 677 (2020)
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 37.
Journal Article
11, 3145 (2020)
The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics. Nature Communications 38.
Journal Article
220, 103754 (2020)
An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 39.
Journal Article
7, 146 (2020)
Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes. Scientific Data 40.
Journal Article
180 (6), pp. 1130 - 1143.e20 (2020)
Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 41.
Journal Article
579 (7799), pp. 448 - 451 (2020)
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 42.
Journal Article
9 (3), 605 (2020)
Probing the environment of emerin by Enhanced ascorbate peroxidase 2 (APEX2)-mediated proximity labeling. Cells 43.
Journal Article
116 (3), pp. 592 - 604 (2020)
Control of p21Cip by BRAP is critical for cardiomyocyte cell cycle progression and survival. Cardiovascular Research 44.
Journal Article
9 (3), 639 (2020)
Urine E-cadherin: A Marker for early detection of kidney injury in diabetic patients. Journal of Clinical Medicine 45.
Journal Article
117 (6), pp. 2948 - 2956 (2020)
Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proceedings of the National Academy of Sciences of the United States of America 46.
Journal Article
18 (1), 8 (2020)
Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. BMC Medicine 47.
Journal Article
10, 3056 (2020)
How to cope with heavy metal ions: Cellular and proteome-level stress response to divalent copper and nickel in Halobacterium salinarum R1 planktonic and biofilm cells. Frontiers in Microbiology 48.
Journal Article
105 (1), pp. 136 - 147 (2020)
The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. Haematologica 49.
Journal Article
577, pp. 717 - 720 (2020)
Structure of the transcription coactivator SAGA. Nature 50.
Journal Article
5 (12), eaay2670 (2019)
The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43. Science Advances 51.
Journal Article
179 (7), pp. 1537 - 1550 (2019)
Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 52.
Journal Article
10 (1), 5054 (2019)
Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. Nature Communications 53.
Journal Article
14 (12), pp. 3333 - 3365 (2019)
A mass spectrometry workflow for measuring protein turnover rates in vivo. Nature Protocols 54.
Journal Article
47 (19), pp. 10313 - 10326 (2019)
The hRPC62 subunit of human RNA polymerase III displays helicase activity. Nucleic Acids Research 55.
Journal Article
294 (44), pp. 16241 - 16254 (2019)
Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. The Journal of Biological Chemistry 56.
Journal Article
LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer. International Journal of Cancer, (in press) (2019)
57.
Journal Article
8 (10), 1129 (2019)
The core proteome of biofilm-grown clinical pseudomonas aeruginosa isolates. Cells 58.
Journal Article
19 (20), 1840091 (2019)
The response of Haloferax volcanii to salt and temperature stress: A proteome study by label-free mass spectrometry. Proteomics 59.
Journal Article
2019, 8298524 (2019)
Proteomic comparison of malignant human germ cell tumor cell lines. Disease Markers 60.
Journal Article
8, e47498 (2019)
Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 61.
Journal Article
140 (8), pp. 681 - 693 (2019)
Loss of protein phosphatase 1 regulatory subunit PPP1R3A promotes atrial fibrillation. Circulation 62.
Journal Article
27 (8), pp. 1195 - 1210 (2019)
Autoinhibition mechanism of the ubiquitin-conjugating enzyme UBE2S by autoubiquitination. Structure 63.
Journal Article
431 (15), pp. 2835 - 2851 (2019)
A MICOS-TIM22 association promotes carrier import into human mitochondria. Journal of Molecular Biology 64.
Journal Article
10, 2885 (2019)
Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 65.
Journal Article
A trap mutant reveals the physiological client spectrum of TRC40. Journal of Cerll Science, (in press) (2019)
66.
Journal Article
18 (6), pp. 1197 - 1209 (2019)
Hypoxia-induced changes in SUMO conjugation affect transcriptional regulation under low oxygen. Molecular and Cellular Proteomics 67.
Journal Article
47 (6), pp. 2932 - 2945 (2019)
Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 68.
Journal Article
16 (4), pp. 557 - 565 (2019)
Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1. RNA Biology 69.
Journal Article
9 (1), 4188 (2019)
Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures. Scientific Reports 70.
Journal Article
216 (3), 704 (2019)
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses. Journal of Experimental Medicine 71.
Journal Article
218 (2), 598 (2019)
ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. The Journal of Cell Biology 72.
Journal Article
16 (4), pp. 469 - 480 (2019)
The nuts and bolts of the Haloferax CRISPR-Cas system I-B. RNA Biology 73.
Journal Article
13 (3), 1800083 (2019)
Proteome profiling by label‐free mass spectrometry reveals differentiated response of Campylobacter jejuni 81–176 to sublethal concentrations of bile acids. Proteomics 74.
Journal Article
10, 2572 (2019)
An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 75.
Journal Article
4 (1), pp. 89 - 96 (2019)
Type IV CRISPR RNA processing and effector complex formation in Aromatoleum aromaticum. Nature Microbiology 76.
Journal Article
25 (13), pp. 3618 - 3630 (2018)
Plk1/Polo phosphorylates Sas-4 at the onset of mitosis for an efficient recruitment of pericentriolar material to centrosomes. Cell Reports 77.
Journal Article
9, 5383 (2018)
RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes. Nature Communications 78.
Journal Article
46 (22), pp. 12109 - 12125 (2018)
Identification of new high affinity targets for Roquin based on structural conservation. Nucleic Acids Research 79.
Journal Article
Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells. The EMBO Journal, In press (e99876) (2018)
80.
Journal Article
8, 16913 (2018)
The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Scientific Reports 81.
Journal Article
9, 4532 (2018)
Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 82.
Journal Article
9, 4234 (2018)
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications 83.
Journal Article
9, 4230 (2018)
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. Nature Communications 84.
Journal Article
46 (16), pp. 8471 - 8482 (2018)
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis. Nucleic Acids Research 85.
Journal Article
13, pp. 26 - 38 (2018)
Crohn's disease patient serum changes protein expression in a human mesenchymal stem cell model in a linear relationship to patients' disease stage and to bone mineral density. Journal of Clinical and Translational Endocrinology 86.
Journal Article
10 (9), e8428 (2018)
Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis. EMBO Molecular Medicine 87.
Journal Article
560 (7720), pp. 607 - 612 (2018)
Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 88.
Journal Article
560 (7720), pp. 601 - 606 (2018)
Structure of paused transcription complex Pol II–DSIF–NELF. Nature 89.
Journal Article
28 (13), pp. 2046 - 2057 (2018)
Endogenous stochastic decoding of the CUG codon by competing Ser- and Leu-tRNAs in Ascoidea asiatica. Current Biology 90.
Journal Article
217 (7), pp. 2329 - 2340 (2018)
Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 91.
Journal Article
3 (12), e99941 (2018)
Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI Insight 92.
Journal Article
8, 8880 (2018)
Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. Scientific Reports 93.
Journal Article
15 (6), pp. 463 - 466 (2018)
Integrative omics - from data to biology. Expert Review of Proteomics 94.
Journal Article
29 (3), pp. 242 - 249 (2018)
Protein profiling of non-model plant Cuminum cyminum by gel-based proteomic approach. Phytochemical Analysis 95.
Journal Article
293 (16), pp. 5781 - 5792 (2018)
Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh in Bacillus subtilis. The Journal of Biological Chemistry 96.
Journal Article
22 (3), pp. 1375 - 1384 (2018)
A new albumin-depletion strategy improves proteomic research of gingival crevicular fluid from periodontitis patients. Clinical Oral Investigations 97.
Journal Article
69 (6), pp. 979 - 992 (2018)
Prp19/Pso4 is an autoinhibited ubiquitin ligase activated by stepwise assembly of three splicing factors. Molecular Cell 98.
Journal Article
3 (3), pp. 367 - 377 (2018)
The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nature Microbiology 99.
Journal Article
107 (5), pp. 595 - 609 (2018)
sRNA41 affects ribosome binding sites within polycistronic mRNAs in Methanosarcina mazei Gö1. Molecular Microbiology