Max-Planck-Institut für Multidisziplinäre Naturwissenschaften

Publikationen

Zeitschriftenartikel (420)

1.

Zeitschriftenartikel

Brás, I. C.; Khani, M. H.; Vasili, E.; Möbius, W.; Riedel, D.; Parfentev, I.; Gerhardt, E.; Fahlbusch, C.; Urlaub, H.; Zweckstetter, M. et al.; Gollisch, T.; Outeiro, T. F.: Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity. Journal of Parkinson's Disease: JPD 12, S. 2397 - 2422 (2022)

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Brandenburg, S.; Drews, L.; Schönberger, H.-L.; Jacob, C. F.; Paulke, N. J.; Beuthner, B. E.; Topci, R.; Kohl, T.; Neuenroth, L.; Kutschka, I. et al.; Urlaub, H.; Kück, F.; Leha, A.; Friede, T.; Seidler, T.; Jacobshagen, C.; Toischer, K.; Puls, M.; Hasenfuß, G.; Lenz, C.; Lehnart, S. E.: Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis. Journal of Molecular and Cellular Cardiology (London) 173, S. 1 - 15 (2022)

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3.

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Giménez, E.; Urlaub, H.; Lockhart, L. J. F.: Photo-tuneable protein nitration by sensitiser tris(bipyridine)-Ruthenium(II) chloride complex. Nitric Oxide - Biology and Chemistry 129 (1), S. 63 - 73 (2022)

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4.

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Ditte, Z.; Silbern, I.; Ditte, P.; Urlaub, H.; Eichele, G.: Extracellular vesicles derived from the choroid plexus trigger the differentiation of neural stem cells. Journal of extracellular vesicles 11 (11), 12276 (2022)

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5.

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Brás, I. C.; Khani, M. H.; Riedel, D.; Parfentev, I.; Gerhardt, E.; van Riesen, C.; Urlaub, H.; Gollisch, T.; Outeiro, T. F.: Ectosomes and exosomes modulate neuronal spontaneous activity. Journal of Proteomics 269, 104721 (2022)

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6.

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Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment. Science 378 (6617), eabq4835 (2022)

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7.

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Bolgi, O.; Silva-Garcia, M.; Ross, B.; Pilla, E.; Kari, V.; Killisch, M.; Spitzner, M.; Stark, N.; Lenz, C.; Weiss, K. et al.; Donzelli, L.; Gorrell, M. D.; Grade, M.; Riemer, J.; Urlaub, H.; Dobbelstein, M.; Huber, R.; Geiss-Friedlander, R.: Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair. EMBO Reports 23 (10), e54136 (2022)

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8.

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Stejerean-Todoran, I.; Zimmermann, K.; Gibhardt, C. S.; Vultur, A.; Ickes, C.; Shannan, B.; Rio, Z. B. d.; Wölling, A.; Cappello, S.; Sung, H.-M. et al.; Shumanska, M.; Zhang, X.; Nanadikar, M.; Latif, M. U.; Wittek, A.; Lange, F.; Waters, A.; Brafford, P.; Wilting, J.; Urlaub, H.; Katschinski, D. M.; Rehling, P.; Lenz, C.; Jakobs, S.; Ellenrieder, V.; Roesch, A.; Schön, M. P.; Herlyn, M.; Stanisz, H.; Bogeski, I.: MCU controls melanoma progression through a redox-controlled phenotype switch. EMBO Reports 23, e54746 (2022)

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9.

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Linnemannstöns, K.; Karuna M, P.; Witte, L.; Choezom, D.; Honemann-Capito, M.; Lagurin, A. S.; Schmidt, C. V.; Shrikhande, S.; Steinmetz, L.-K.; Möbius, W. et al.; Lenz, C.; Gross, J. C.: Microscopic and biochemical monitoring of endosomal trafficking and extracellular vesicle secretion in an endogenous in vivo model. Journal of extracellular vesicles 11 (9), 12263 (2022)

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10.

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Werner, M.; Dyas, A.; Parfentev, I.; Schmidt, G. E.; Mieczkowska, I. K.; Müller-Kirschbaum, L. C.; Müller, C.; Kalkhof, S.; Reinhardt, O.; Urlaub, H. et al.; Alves, F.; Gallwas, J.; Prokakis, E.; Wegwitz, F.: ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness. Cell Death and Disease 13, 762 (2022)

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11.

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Kluever, V.; Russo, B.; Mandad, S.; Kumar, N. H.; Alevra, M.; Ori, A.; Rizzoli, S. O.; Urlaub, H.; Schneider, A.; Fornasiero, E. F.: Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration. Science Advances 8, eabn4437 (2022)

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12.

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Yi, S.-H.; Petrychenko, V.; Schliep, J. E.; Goyal, A.; Linden, A.; Chari, A.; Urlaub, H.; Stark, H.; Rodnina, M. V.; Adio, S. et al.; Fischer, N.: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research 50 (9), S. 5282 - 5298 (2022)

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13.

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Upmanyu, N.; Jin, J.; von der Emde, H.; Ganzella, M.; Bösche, L.; Malviya, V. N.; Zhuleku, E.; Politi, A. Z.; Ninov, M.; Silbern, I. et al.; Leutenegger, M.; Urlaub, H.; Riedel, D.; Preobraschenski, J.; Milosevic, I.; Hell, S. W.; Jahn, R.; Sambandan, S.: Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3. Neuron 110 (9), S. 1483 - 1497 (2022)

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14.

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Mishto, M.; Horokhovskyi, Y.; Cormican, J. A.; Yang, X.; Lynham, S.; Urlaub, H.; Liepe, J.: Database search engines and target database features impinge upon the identification of post‐translationally cis‐spliced peptides in HLA class I immunopeptidomes. Proteomics 22 (10), e2100226 (2022)

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15.

Zeitschriftenartikel

Wortz, J.; Smith, V.; Fallmann, J.; König, S.; Thuraisingam, T.; Walther, P.; Urlaub, H.; Stadler, P. F.; Allers, T.; Hille, F. et al.; Marchfelder, A.: Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair. Frontiers in Microbiology 13, 822304 (2022)

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supplementary-material

16.

Zeitschriftenartikel

Yao, Y.; Kim, G.; Shafer, S.; Chen, Z.; Kubo, S.; Ji, Y.; Luo, J.; Yang, W.; Perner, S. P.; Kanellopoulou, C. et al.; Park, A. Y.; Jiang, P.; Li, J.; Baris, S.; Aydiner, E.K.; Ertem, D.; Mulder, D. J.; Warner, N.; Griffiths, A. M.; Topf-Olivestone, C.; Kori, M.; Werner, L...; Ouahed, J.; Field, M.; Liu, C.; Schwarz, B.; Bosio, C. M.; Ganesan, S.; Song, J.; Urlaub, H.; Oellerich, T.; Malaker, S. A.; Zheng, L.; Bertozzi, C. R.; Zhang, Y.; Matthews, H.; Montgomery, W.; Shih, H.-Y.; Jiang, J.; Jones, M.; Baras, A.; Shuldiner, A.; Gonzaga-Jauregui, C.; Snapper, S. B.; Muise, A. M.; Shouval, D. S.; Ozen, A.; Pan, K.-T.; Wu, C.; Lenardo, M. J.: Mucus sialylation determines intestinal host-commensal homeostasis. Cell 185 (7), S. 1172 - 1188.e28 (2022)

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17.

Zeitschriftenartikel

Düster, R.; Ji, Y.; Pan, K.-T.; Urlaub, H.; Geyer, M.: Functional characterization of the human Cdk10/Cyclin Q complex. Open Biology 12 (3), 210381 (2022)

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18.

Zeitschriftenartikel

Georgiou, M.; Yang, C.; Atkinson, R.; Pan, K.‐.; Buskin, A.; Molina, M. M.; Collin, J.; Al‐Aama, J.; Goertler, F.; Ludwig, S. E. J. et al.; Davey, T.; Lührmann, R.; Nagaraja‐Grellscheid, S.; Johnson, C. A.; Ali, R.; Armstrong, L.; Korolchuk, V.; Urlaub, H.; Mozaffari‐Jovin, S.; Lako, M.: Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient‐induced pluripotent stem cell‐derived retinal pigment epithelium cells. Clinical and Translational Medicine 12 (3), e759 (2022)

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19.

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Chang, H.-F.; Schirra, C.; Ninov, M.; Hahn, U.; Ravichandran, K.; Krause, E.; Becherer, U.; Bálint, Š.; Harkiolaki, M.; Urlaub, H. et al.; Valitutti, S.; Baldari, C. T.; Dustin, M. L.; Jahn, R.; Rettig, J.: Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes. Nature Communications 13, 1029 (2022)

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20.

Zeitschriftenartikel

Fang, P.; Ji, Y.; Oellerich, T.; Urlaub, H.; Pan, K.-T.: Strategies for Proteome-Wide Quantification of Glycosylation Macro- and Micro-Heterogeneity. International Journal of Molecular Sciences 23 (3), 1609 (2022)

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21.

Zeitschriftenartikel

Wilke, A. C.; Doebele, C.; Zindel, A.; Lee, K. S.; Rieke, S. A.; Ceribelli, M.; Comoglio, F.; Phelan, J.D.; Wang, J. Q.; Pikman, Y. et al.; Jahn, D.; Häupl, B.; Schneider, C.; Scheich, S.; Tosto, F. A.; Bohnenberger, H.; Stauder, P.; Schnütgen, F.; Slabicki, M.; Coulibaly, Z. A.; Wolf, S.; Bojarczuk, K.; Chapuy, B.; Brandts, C. H.; Stroebel, P.; Lewis, C. A.; Engelke, M.; Xu, X.; Kim, H.; Dang, T. H.; Schmitz, R.; Hodson, D. J.; Stegmaier, K.; Urlaub, H.; Serve, H.; Schmitt, C. A.; Kreuz, F.; Knittel, G.; Rabinowitz, J. D.; Reinhardt, H. C.; Vander Heiden, M. G.; Thomas, C.; Staudt, L. M.; Zenz, T.; Oellerich, T.: SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. Blood 139 (4), S. 538 - 553 (2022)

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22.

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Elakad, O.; Häupl, B.; Labitzky, V.; Yao, S.; Küffer, S.; von Hammerstein-Equord, A.; Danner, B. C.; Jücker, M.; Urlaub, H.; Lange, T. et al.; Ströbel, P.; Oellerich, T.; Bohnenberger, H.: Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer. npj Precision Oncology 6, 52 (2022)

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23.

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Farkas, Á.; Urlaub, H.; Bohnsack, K. E.; Schwappach, B.: Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway. Journal of Cell Biology 221 (6), e202201036 (2022)

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24.

Zeitschriftenartikel

Jayavelu, A. K.; Wolf, S.; Buettner, F.; Alexe, G.; Häupl, B.; Comoglio, F.; Schneider, C.; Doebele, C.; Fuhrmann, D. C.; Wagner, S. et al.; Donato, E.; Andresen, C.; Wilke, A. C.; Zindel, A.; Jahn, D.; Splettstoesser, B.; Plessmann, U.; Münch, S.; Abou-El-Ardat, K.; Makowka, P.; Acker, F.; Enssle, J. C.; Cremer, A.; Schnütgen, F.; Kurrle, N.; Chapuy, B.; Löber, J.; Hartmann, S.; Wild, P. J.; Wittig, I.; Hübschmann, D.; Kaderali, L.; Cox, J.; Brüne, B.; Röllig, C.; Thiede, C.; Steffen, B.; Bornhäuser, M.; Trumpp, A.; Urlaub, H.; Stegmaier, K.; Serve, H.; Mann, M.; Oellerich, T.: The proteogenomic subtypes of acute myeloid leukemia. Cancer Cell 40 (3), S. 301 - 317.e12 (2022)

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25.

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Meyer, A.; Kehl, A.; Cui, C.; Reichardt, F. A. K.; Hecker, F.; Funk, L.-M.; Ghosh, M. K.; Pan, K. T.; Urlaub, H.; Tittmann, K. et al.; Stubbe, J.; Bennati, M.: 19F Electron-nuclear double resonance reveals interaction between redox-active tyrosines across the α/β interface of E. coli ribonucleotide reductase. Journal of the American Chemical Society 144, S. 11270 - 11282 (2022)

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26.

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Moll, A.; Ramirez, L. M.; Ninov, M.; Schwarz, J.; Urlaub, H.; Zweckstetter, M.: Hsp multichaperone complex buffers pathologically modified Tau. Nature Communications 13, 3668 (2022)

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27.

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Richter, A.; Fichtner, A.; Joost, J.; Brockmeyer, P.; Kauffmann, P.; Schliephake, H.; Hammerstein‐Equord, A.; Kueffer, S.; Urlaub, H.; Oellerich, T. et al.; Ströbel, P.; Bohnenberger, H.; Bremmer, F.: Quantitative proteomics identifies biomarkers to distinguish pulmonary from head and neck squamous cell carcinomas by immunohistochemistry. The Journal of Pathology: Clinical Research 8 (1), S. 33 - 47 (2022)

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28.

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Richter, A.; Fichtner, A.; Joost, J.; Brockmeyer, P.; Kauffmann, P.; Schliephake, H.; Hammerstein‐Equord, A.; Kueffer, S.; Urlaub, H.; Oellerich, T. et al.; Ströbel, P.; Bohnenberger, H.; Bremmer, F.: Quantitative proteomics identifies biomarkers to distinguish pulmonary from head and neck squamous cell carcinomas by immunohistochemistry. The Journal of Pathology: Clinical Research 8 (1), S. 33 - 47 (2022)

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29.

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Weninger, G.; Pochechueva, T.; El Chami, D.; Luo, X.; Kohl, T.; Brandenburg, S.; Urlaub, H.; Guan, K.; Lenz, C.; Lehnart, S. E.: Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes. Scientific Reports 12, 10387 (2022)

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30.

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Barbarics, B.; Eildermann, K.; Kaderali, L.; Cyganek, L.; Plessmann, U.; Bodemeyer, J.; Paul, T.; Ströbel, P.; Urlaub, H.; Tirilomis, T. et al.; Lenz, C.; Bohnenberger, H.: Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis. Scientific Reports 11, 24389 (2021)

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31.

Zeitschriftenartikel

James, C.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Sequestosome 1 is part of the interaction network of VAPB. International Journal of Molecular Sciences 22 (24), 13271 (2021)

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32.

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Mühlhausen, S.; Schmitt, H. D.; Plessmann, U.; Mienkus, P.; Sternisek, P.; Perl, T.; Weig, M.; Urlaub, H.; Bader, O.; Kollmar, M.: Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans. BMC Biology 19, 258 (2021)

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33.

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Güran, A.; Ji, Y.; Fang, P.; Pan, K.-T.; Urlaub, H.; Avkiran, M.; Lenz, C.: Quantitative analysis of the cardiac phosphoproteome in response to acute β-adrenergic receptor stimulation in vivo. International Journal of Molecular Sciences 22 (22), 12584 (2021)

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34.

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Fianu, I.; Chen, Y.; Dienemann, C.; Dybkov, O.; Linden, A.; Urlaub, H.; Cramer, P.: Structural basis of Integrator-mediated transcription regulation. Science 374 (6569), S. 883 - 887 (2021)

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35.

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Cruz-Zaragoza, L. D.; Dennerlein, S.; Linden, A.; Yousefi, R.; Lavdovskaia, E.; Aich, A.; Falk, R. R.; Gomkale, R.; Schöndorf, T.; Bohnsack, M. T. et al.; Richter-Dennerlein, R.; Urlaub, H.; Rehling, P.: An in vitro system to silence mitochondrial gene expression. Cell 184 (23), S. 5824 - 5837.e15 (2021)

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36.

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Aquino, G. R. R.; Hackert, P.; Krogh, N.; Pan, K. T.; Jaafar, M.; Henras, A. K.; Nielsen, H.; Urlaub, H.; Bohnsack, K. E.; Bohnsack, M. T.: The RNA helicase Dbp7 promotes domain V/VI compaction and stabilization of inter-domain interactions during early 60S assembly. Nature Communications 12, 6152 (2021)

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37.

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Kokic, G.; Wagner, F. R.; Chernev, A.; Urlaub, H.; Cramer, P.: Structural basis of human transcription–DNA repair coupling. Nature 598 (7880), S. 368 - 372 (2021)

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38.

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Gomkale, R.; Linden, A.; Neumann, P.; Schendzielorz, A. B.; Stoldt, S.; Dybkov, O.; Kilisch, M.; Schulz, C.; Cruz-Zaragoza, L. D.; Schwappach, B. et al.; Ficner, R.; Jakobs, S.; Urlaub, H.; Rehling, P.: Mapping protein interactions in the active TOM-TIM23 supercomplex. Nature Communications 12, 5715 (2021)

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39.

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Zhang, Z.; Rigo, N.; Dybkov, O.; Fourmann, J. B.; Will, C. L.; Kumar, V.; Urlaub, H.; Stark, H.; Lührmann, R.: Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature 596 (7871), S. 296 - 300 (2021)

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40.

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Helm, M. S.; Dankovich, T. M.; Mandad, S.; Rammner, B.; Jähne, S.; Salimi, V.; Koerbs, C.; Leibrandt, R.; Urlaub, H.; Schikorski, T. et al.; Rizzoli, S. O.: A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines. Nature Neuroscience 24 (8), S. 1151 - 1162 (2021)

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41.

Zeitschriftenartikel

Chen, Y.; Vos, S. M.; Dienemann, C.; Ninov, M.; Urlaub, H.; Cramer, P.: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 81 (16), S. 3386 - 3399.e10 (2021)

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42.

Zeitschriftenartikel

Mishto, M.; Rodriguez-Hernandez, G.; Neefjes, J.; Urlaub, H.; Liepe, J.: Response: Commentary: An In Silico–In Vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Frontiers in immunology 12, 679836 (2021)

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43.

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Fang, P.; Ji , Y.; Silbern, I.; Viner, R.; Oellerich, T.; Pan, K. T.; Urlaub, H.: Evaluation and optimization of high-field asymmetric waveform ion-mobility spectrometry for multiplexed quantitative site-specific N-glycoproteomics. Analytical Chemistry 93 (25), S. 8846 - 8855 (2021)

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44.

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Martinez Hernandez, A.; Silbern, I.; Geffers, I.; Tatenhorst, L.; Becker, S.; Urlaub, H.; Zweckstetter, M.; Griesinger, C.; Eichele, G.: Low-Expressing synucleinopathy mouse models based on oligomer-forming mutations and C-terminal truncation of α-synuclein. Frontiers in Neuroscience 15, 643391 (2021)

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45.

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Hillen, H. S.; Lavdovskaia, E.; Nadler, F.; Hanitsch, E.; Linden, A.; Bohnsack, K. E.; Urlaub, H.; Richter-Dennerlein, R.: Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling. Nature Communications 12, 3672 (2021)

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46.

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Yildirim, A.; Mozaffari-Jovin, S.; Wallisch, A. K.; Schäfer, J.; Ludwig, S. E. J.; Urlaub, H.; Lührmann, R.; Wolfrum, U.: SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes. Nucleic Acids Research 49 (10), S. 5845 - 5866 (2021)

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47.

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Osman, S.; Mohammad, E.; Lidschreiber, M.; Stuetzer, A.; Bazsó, F. L.; Maier, K. C.; Urlaub, H.; Cramer, P.: The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 296, 100734 (2021)

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48.

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Wensien, M.; Rabe von Pappenheim, F.; Funk, L. M.; Kloskowski, P.; Curth, U.; Diederichsen, U.; Uranga, J.; Ye, J.; Fang, P.; Pan, K. T. et al.; Urlaub, H.; Mata, R. A.; Sautner, V.; Tittmann, K.: A lysine–cysteine redox switch with an NOS bridge regulates enzyme function. Nature 593 (7859), S. 460 - 464 (2021)

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49.

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Hallumi, E.; Shalah, R.; Lo, W. L.; Corso, J.; Oz, I.; Beach, D.; Wittman, S.; Isenberg, A.; Sela, M.; Urlaub, H. et al.; Weiss, A.; Yablonski, D.: Itk promotes the integration of TCR and CD28 costimulation through its direct substrates SLP-76 and Gads. The Journal of Immunology 206 (10), S. 2322 - 2337 (2021)

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50.

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Naarman-de Vries, I. S.; Senatore, R.; Moritz, B.; Marx, G.; Urlaub, H.; Niessing, D.; Ostareck, D. H.; Ostareck-Lederer, A.: Methylated HNRNPK acts on RPS19 to regulate ALOX15 synthesis in erythropoiesis. Nucleic Acids Research 49 (6), S. 3507 - 3523 (2021)

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51.

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Wohlgemuth, I.; Garofalo, R.; Samatova, E. N.; Günenç, A. N.; Lenz, C.; Urlaub, H.; Rodnina, M. V.: Translation error clusters induced by aminoglycoside antibiotics. Nature Communications 12, 1830 (2021)

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52.

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Peper, J.; Kownatzki-Danger, D.l.; Weninger, G.; Seibertz, F.; Pronto, J. R. D.; Sutanto, H.; Pacheu-Grau, D.; Hindmarsh, R.; Brandenburg, S.; Kohl, T. et al.; Hasenfuss, G.; Gotthardt, M.; Rog-Zielinska, E. A.; Wollnik, B.; Rehling, P.; Urlaub, H.; Wegener, J.; Heijman, J.; Voigt, N.; Cyganek, L.; Lenz, C.; Lehnart, S. E.: Caveolin3 stabilizes McT1-mediated lactate/proton transport in cardiomyocytes. Circulation Research 128 (6), S. e102 - e120 (2021)

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53.

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Barysch, S. V.; Stankovic‐Valentin, N.; Miedema, K.-T.; Karaca, S.; Doppel, J.; Nait Achour, T.; Vasudeva, A.; Wolf, L.; Sticht, C.; Urlaub, H. et al.; Melchior, F.: Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling. EMBO Reports 22 (3), e49651 (2021)

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54.

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Yatsenko, A. S.; Kucherenko, M. M.; Xie, Y.; Urlaub, H.; Shcherbata, H. R.: Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization. eLife 10, e63868 (2021)

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55.

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Szczęśniak, P.; Henke, T.; Fröhlich, S.; Plessmann, U.; Urlaub, H.; Leng, L.; Bucala, R.; Grosse, R.; Meinhardt, A.; Klug, J.: Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independent of its receptor CD74/CD44. Journal of Cell Science 134 (3), jcs217356 (2021)

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56.

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Zheng, X.; Zhang, L.; Kuang, Y.; Venkataramani, V.; Jin, F.; Hein, K.; Zafeiriou, M. P.; Lenz, C.; Moebius, W.; Kilic, E. et al.; Hermann, D. M.; Weber, M. S.; Urlaub, H.; Zimmermann, W.-H.; Bähr, M.; Doeppner, T. R.: Extracellular vesicles derived from neural progenitor cells: A preclinical evaluation for stroke treatment in mice. Translational Stroke Research 12 (1), S. 185 - 203 (2021)

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57.

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Valpadashi, A.; Callegari, S.; Linden, A.; Neumann, P.; Ficner, R.; Urlaub, H.; Deckers, M.; Rehling, P.: Defining the architecture of the human TIM22 complex by chemical crosslinking. FEBS Letters 595 (2), S. 157 - 168 (2021)

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58.

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Kraxner, J.; Lorenz, C.; Menzel, J.; Parfentev, I.; Silbern, I.; Denz, M.; Urlaub, H.; Schwappach, B.; Köster, S.: Post-translational modifications soften vimentin intermediate filaments. Nanoscale 13 (1), S. 380 - 387 (2021)

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59.

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Blersch, K. F.; Burchert, J.-P.; August, S.-C.; Welp, L.; Neumann, P.; Köster, S.; Urlaub, H.; Ficner, R.: Structural model of the M7G46 methyltransferase TrmB in complex with tRNA. RNA Biology 18 (12), S. 2466 - 2479 (2021)

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Sievers, K.; Welp, L.; Urlaub, H.; Ficner, R.: Structural and functional insights into human tRNA guanine transgylcosylase. RNA Biology 18 (Suppl. 1), S. 382 - 396 (2021)

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Silbern, I.; Pan, K. T.; Fiosins, M.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.; Urlaub, H.; Jahn, R.: Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling. Molecular and Cellular Proteomics 20, 100061 (2021)

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Townsend, C.; Leelaram, M. N.; Agafonov, D. E.; Dybkov, O.; Will, C. L.; Bertram, K.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science 370 (6523), eabc3753 (2020)

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Lavdovskaia, E.; Denks, K.; Nadler, F.; Steube, E.; Linden, A.; Urlaub, H.; Rodnina, M. V.; Richter-Dennerlein, R.: Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. Nucleic Acids Research 48 (22), S. 12929 - 12942 (2020)

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Netz, E.; Dijkstra, T. M. H.; Sachsenberg, T.; Zimmermann, L.; Walzer, M.; Monecke, T.; Ficner, R.; Dybkov, O.; Urlaub, H.; Kohlbacher, O.: OpenPepXL: An open-source tool for sensitive identification of cross-linked peptides in XL-MS. Molecular and Cellular Proteomics 19 (12), S. 2157 - 2167 (2020)

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Leitner, A.; Bonvin, A. M. J. J.; Borchers, C. H.; Chalkley, R. J.; Chamot-Rooke, J.; Combe, C. W.; Cox, J.; Dong, M.-Q.; Fischer, L.; Götze, M. et al.; Gozzo, F. C.; Heck, A. J. R.; Hoopmann, M. R.; Huang, L.; Ishihama, Y.; Jones, A. R.; Kalisman, N.; Kohlbacher, O.; Mechtler, K.; Moritz, R. L.; Netz, E.; Novak, P.; Petrotchenko, E.; Sali, A.; Scheltema, R. A.; Schmidt, C.; Schriemer, D.; Sinz, A.; Sobott, F.; Stengel, F.; Thalassinos, K.; Urlaub, H.; Viner, R.; Vizcaíno, J. A.; Wilkins, M. R.; Rappsilber, J.: Toward increased reliability, transparency, and accessibility in cross-linking mass spectrometry. Structure 28 (11), S. 1259 - 1268 (2020)

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Fish, K.; Comoglio, F.; Shaffer, A. L.; Jia, Y.; Pan, K. T.; Scheich, S.; Oellerich, A.; Doebele, C.; Ikeda, M.; Schaller, S. J. et al.; Nguyen, H.; Muppidi, J.; Wright, G. W.; Urlaub, H.; Serve, H.; Staudtd, L. M.; Longnecker, R.; Oellerich, T.: Rewiring of B cell receptor signaling by Epstein–Barr virus LMP2A. Proceedings of the National Academy of Sciences of the USA 117 (42), S. 26318 - 26327 (2020)

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Stützer, A.; Welp, L.; Raabe, M.; Sachsenberg, T.; Kappert, C.; Wulf, A.; Lau, A. M.; David, S.-S.; Chernev, A.; Kramer, K. et al.; Politis, A.; Kohlbacher, O.; Fischle, W.; Urlaub, H.: Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry. Nature Communications 11, 5250 (2020)

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Bertram, K.; El Ayoubi, L.; Dybkov, O.; Agafonov, D.; Will, C. L.; Hartmuth, K.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Structural insights into the roles of metazoan-specific splicing factors in the human step 1 spliceosome. Molecular Cell 80 (1), S. 127 - 139.e6 (2020)

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Vahsen, B. F.; Ribas, V. T.; Sundermeyer, J.; Boecker, A.; Dambeck, V.; Lenz, C.; Shomroni, O.; Gomes, L. C.; Tatenhorst, L.; Barski, E. et al.; Roser, A.-E.; Michel, U.; Urlaub, H.; Salinas, G.; Bähr, M.; Koch, J. C.; Lingor, P.: Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. Cell Death and Differentiation 27 (10), S. 2810 - 2827 (2020)

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Menzel, J.; Kownatzki-Danger, D.; Tokar, S.; Ballone, A.; Unthan-Fechner, K.; Kilisch, M.; Lenz, C.; Urlaub, H.; Mori, M.; Ottmann, C. et al.; Shattock, M. J.; Lehnart, S. E.; Schwappach, B.: 14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban. Science Signaling 13 (647), eaaz1436 (2020)

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Ukmar-Godec, T.; Fang, P.; Ibáñez de Opakua, A.; Henneberg, F.; Godec, A.; Pan, K. T.; Cima-Omori, M.-S.; Chari, A.; Mandelkow, E.; Urlaub, H. et al.; Zweckstetter, M.: Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 6 (30), eaba3916 (2020)

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Zhang, Z.; Will, C. L.; Bertram, K.; Dybkov, O.; Hartmuth, K.; Agafonov, D. E.; Hofele, R. V.; Urlaub, H.; Kastner, B.; Lührmann, R. et al.; Stark, H.: Molecular architecture of the human 17S U2 snRNP. Nature 583 (7815), S. 310 - 313 (2020)

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Königsmann, T.; Parfentev, I.; Urlaub, H.; Riedel, D.; Schuh, R.: The bicistronic gene würmchen encodes two essential components for epithelial development in Drosophila. Developmental Biology 463 (1), S. 53 - 62 (2020)

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Linden, A.; Deckers, M.; Parfentev, I.; Pflanz, R.; Homberg, B.; Neumann, P.; Ficner, R.; Rehling, P.; Urlaub, H.: A Cross-linking mass spectrometry approach defines protein interactions in yeast mitochondria. Molecular and Cellular Proteomics 19 (7), S. 1161 - 1178 (2020)

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Vos, S. M.; Farnung, L.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 27 (7), S. 668 - 677 (2020)

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Schulze, S.; Adams, Z.; Cerletti, M.; Castro, R. D.; Ferreira-Cerca, S.; Fufezan, C.; Giménez, M. I.; Hippler, M.; Jevtic, Z.; Knüppel, R. et al.; Legerme, G.; Lenz, C.; Marchfelder, A.; Maupin-Furlow, J.; Paggi, R. A.; Pfeiffer, F.; Poetsch, A.; Urlaub, H.; Pohlschroder, M.: The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics. Nature Communications 11, 3145 (2020)

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Parfentev, I.; Schilbach, S.; Cramer, P.; Urlaub, H.: An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 220, 103754 (2020)

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Specht, G.; Roetschke, H. P.; Mansurkhodzhaev, A.; Henklein, P.; Textoris-Taube, K.; Urlaub, H.; Mishto, M.; Liepe, J.: Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes. Scientific Data 7, 146 (2020)

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Singh, K.; Graf, B.; Linden, A.; Sautner, V.; Urlaub, H.; Tittmann, K.; Stark, H.; Chari, A.: Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 180 (6), S. 1130 - 1143.e20 (2020)

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Wagner, F. R; Dienemann, C.; Wang, H.; Stützer, A.; Tegunov, D.; Urlaub, H.; Cramer, P.: Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 579 (7799), S. 448 - 451 (2020)

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Müller, M.; James, C.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Probing the environment of emerin by Enhanced ascorbate peroxidase 2 (APEX2)-mediated proximity labeling. Cells 9 (3), 605 (2020)

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Volland, C.; Schott, P.; Didié, M.; Männer, J.; Unsöld, B.; Toischer, K.; Schmidt, C.; Urlaub, H.; Nickels, K.; Knöll, R. et al.; Schmidt, A.; Guan, K.; Hasenfuß, G.; Seidler, T.: Control of p21^Cip by BRAP is critical for cardiomyocyte cell cycle progression and survival. Cardiovascular Research 116 (3), S. 592 - 604 (2020)

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Koziolek, M.; Mueller, G. A.; Dihazi, G. H.; Jung, K.; Altubar, C.; Wallbach, M.; Markovic, I.; Raddatz, D.; Jahn, O.; Karaköse, H. et al.; Lenz, C.; Urlaub, H.; Dihazi, A.; El Meziane, A.; Dihazi, H.: Urine E-cadherin: A Marker for early detection of kidney injury in diabetic patients. Journal of Clinical Medicine 9 (3), 639 (2020)

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Hamann, F.; Schmitt, A.; Favretto, F.; Hofele, R.; Neumann, P.; Xiang, S. Q.; Urlaub, H.; Zweckstetter, M.; Ficner, R.: Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proceedings of the National Academy of Sciences of the United States of America 117 (6), S. 2948 - 2956 (2020)

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Yatsenko, A. S.; Kucherenko, M. M.; Xie, Y.; Aweida, D.; Urlaub, H.; Scheibe, R. J.; Cohen, S.; Shcherbata, H. R.: Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. BMC Medicine 18 (1), 8 (2020)

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Völkel, S.; Hein, S.; Benker, N.; Pfeifer, F.; Lenz, C.; Losensky, G.: How to cope with heavy metal ions: Cellular and proteome-level stress response to divalent copper and nickel in Halobacterium salinarum R1 planktonic and biofilm cells. Frontiers in Microbiology 10, 3056 (2020)

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Godavarthy, P. S.; Kumar, R.; Herkt, S. C.; Pereira, R. S.; Hayduk, N.; Weissenberger, E. S.; Aggoune, D.; Manavski, Y.; Lucas, T.; Pan, K. T. et al.; Voutsinas, J. M.; Wu, Q.; Müller, M. C.; Saussele, S.; Oellerich, T.; Oehler, V. G.; Lausen, J.; Krause, D. S.: The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. Haematologica 105 (1), S. 136 - 147 (2020)

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Wang, H.; Dienemann, C.; Stützer, A.; Urlaub, H.; Cheung, A. C. M.; Cramer, P.: Structure of the transcription coactivator SAGA. Nature 577, S. 717 - 720 (2020)

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Keihani, S.; Klüver, V.; Mandad, S.; Bansal, V.; Rahman, R.; Fritsch, E.; Gomes, L. C.; Gärtner, A.; Kügler, S.; Urlaub, H. et al.; Wren, J. D.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.: The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43. Science Advances 5 (12), eaay2670 (2019)

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Grimm, C.; Hillen, H. S.; Bedenk, K.; Bartuli, J.; Neyer, S.; Zhang, Q.; Hüttenhofer, A.; Erlacher, M.; Dienemann, C.; Schlosser, A. et al.; Urlaub, H.; Böttcher, B.; Szalay, A. A.; Cramer, P.; Fischer, U.: Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 179 (7), S. 1537 - 1550 (2019)

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Gowravaram, M.; Schwarz, J.; Khilji, S. K.; Urlaub, H.; Chakrabarti, S.: Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. Nature Communications 10 (1), 5054 (2019)

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Alevra, M.; Mandad, S.; Ischebeck, T.; Urlaub, H.; Rizzoli, S. O.; Fornasiero, E. F.: A mass spectrometry workflow for measuring protein turnover rates in vivo. Nature Protocols 14 (12), S. 3333 - 3365 (2019)

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Ayoubi, L. E.; Dumay-Odelot, H.; Chernev, A.; Boissier, F.; Minvielle-Sébastia, L.; Urlaub, H.; Fribourg, S.; Teichmann, M.: The hRPC62 subunit of human RNA polymerase III displays helicase activity. Nucleic Acids Research 47 (19), S. 10313 - 10326 (2019)

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James, C.; Müller, M.; Goldberg, M. W.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. The Journal of Biological Chemistry 294 (44), S. 16241 - 16254 (2019)

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Blazquez, R.; Rietkötter, E.; Wenske, B.; Wlochowitz, D.; Sparrer, D.; Vollmer, E.; Müller, G.; Seegerer, J.; Sun, X.; Dettmer, K. et al.; Barrantes-Freer, A.; Stange, L.; Utpatel, K.; Bleckmann, A.; Treiber, H.; Bohnenberger, H.; Lenz, C.; Schulz, M.; Reimelt, C.; Hackl, C.; Grade, M.; Büyüktas, D.; Siam, L.; Balkenhol, M.; Stadelmann, C.; Kube, D.; Krahn, M. P.; Proescholdt, M. A.; Riemenschneider, M. J.; Evert, M.; Oefner, P. J.; Klein, C. A.; Hanisch, U. K.; Binder, C.; Pukrop, T.: LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer. International Journal of Cancer, (in press) (2019)

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Erdmann, J.; Thöming, J. G.; Pohl, S.; Pich, A.; Lenz, C.; Häussler, S.: The core proteome of biofilm-grown clinical pseudomonas aeruginosa isolates. Cells 8 (10), 1129 (2019)

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Jevtic, Z.; Stoll, B.; Pfeiffer, F.; Sharma, K.; Urlaub, H.; Marchfelder, A.; Lenz, C.: The response of Haloferax volcanii to salt and temperature stress: A proteome study by label-free mass spectrometry. Proteomics 19 (20), 1840091 (2019)

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Bremmer, F.; Bohnenberger, H.; Küffer, S.; Oellerich, T.; Serve, H.; Urlaub, H.; Strauss, A.; Maatoug, Y.; Behnes, C. L.; Oing, C. et al.; Radzun, H. J.; Ströbel, P.; Balabanov, S.; Honecker, F.: Proteomic comparison of malignant human germ cell tumor cell lines. Disease Markers 2019, 8298524 (2019)

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Yagensky, O.; Kohansal-Nodehi, M.; Gunaseelan, S.; Rabe, T.; Zafar, S.; Zerr, I.; Haertig, W.; Urlaub, H.; Chua, J.: Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 8, e47498 (2019)

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