Publikationen

Zeitschriftenartikel (466)

1.
Zeitschriftenartikel
Phelan, J. D.; Scheich, S.; Choi, J.; Wright, G. W.; Häupl, B.; Young, R. M.; Rieke, S. A.; Pape, M.; Ji, Y.; Urlaub, H. et al.; Bolomsky, A.; Doebele, C.; Zindel, A.; Wotapek, T.; Kasbekar, M.; Collinge, B.; Huang, D. W.; Coulibaly, Z. A.; Morris, V. M.; Zhuang, X.; Enssle, J. C.; Yu, X.; Xu, W.; Yang, Y.; Zhao, H.; Wang, Z.; Tran, A. D.; Shoemaker, C. J.; Shevchenko, G.; Hodson, D. J.; Shaffer, A. L.; Staudt, L. M.; Oellerich, T.: Response to Bruton’s tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy. Cancer Cell 42 (2), S. 238 - 252.e9 (2024)
2.
Zeitschriftenartikel
Düring, J.; Wolter, M.; Toplak, J. J.; Torres, C.; Dybkov, O.; Fokkens, T. J.; Bohnsack, K. E.; Urlaub, H.; Steinchen, W.; Dienemann, C. et al.; Lorenz, S.: Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1. Nature Structural & Molecular Biology 31, S. 364 - 377 (2024)
3.
Zeitschriftenartikel
Soh, W. T.; Roetschke, H. P.; Cormican, J. A.; Teo, B.F.; Chiam, N. C.; Raabe, M.; Pflanz, R.; Henneberg, F.; Becker, S.; Chari, A. et al.; Liu, H.; Urlaub, H.; Liepe, J.; Mishto, M.: Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing. Nature Communications 15 (1), 1147 (2024)
4.
Zeitschriftenartikel
Kokic, G.; Yakoub, G.; van den Heuvel, D.; Wondergem, A. P.; van der Meer, P. J.; van der Weegen, Y.; Chernev, A.; Fianu, I.; Fokkens, T. J.; Lorenz, S. et al.; Urlaub, H.; Cramer, P.; Luijsterburg, M. S.: Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair. Nature Structural & Molecular Biology (2024)
5.
Zeitschriftenartikel
Carmona, A.; Carboni, E.; Gomes, L.C.; Roudeau, S.; Maass, F.; Lenz, C.; Ortega, R.; Lingor, P.: Metal dyshomeostasis in the substantia nigra of patients with Parkinson's disease or multiple sclerosis. Journal of Neurochemistry 168 (2), S. 128 - 141 (2024)
6.
Zeitschriftenartikel
Cepeda, A. P.; Ninov, M.; Neef, J.; Parfentev, I.; Kusch, K.; Reisinger, E.; Jahn, R.; Moser, T.; Urlaub, H.: Proteomic Analysis Reveals the Composition of Glutamatergic Organelles of Auditory Inner Hair Cells. Molecular & Cellular Proteomics 23 (2), 100704 (2024)
7.
Zeitschriftenartikel
Egbert, J. R.; Silbern, I.; Uliasz, T. F.; Lowther, K. M.; Yee, S.-P.; Urlaub, H.; Jaffe, L. A.: Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase. Biology of Reproduction 110 (1), S. 102 - 115 (2024)
8.
Zeitschriftenartikel
Altas, B.; Tuffy, L. P.; Patrizi, A.; Dimova, K.; Soykan, T.; Brandenburg, C.; Romanowski, A. J.; Whitten, J. R.; Robertson, C. D.; Khim, S. N. et al.; Crutcher, G. W.; Ambrozkiewicz, M.; Yagensky, O.; Krüger-Burg, D. D.; Hammer, M.; Hsiao, H.-H.; Laskowski, P. R.; Dyck, L.; Puche, A. C.; Sassoè-Pognetto, M.; Chua, J. J. E.; Urlaub, H.; Jahn, O.; Brose, N.; Poulopoulos, A.: Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses. Biological Psychiatry, in press (2023)
9.
Zeitschriftenartikel
Kanwal, N.; Krogh, N.; Memet, I.; Lemus-Diaz, N.; Thomé, C. C.; Welp, L. M.; Mizi, A.; Hackert, P.; Papantonis, A.; Urlaub, H. et al.; Nielsen, H.; Bohnsack, K. E.; Bohnsack, M. T.: GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners. Nucleic Acids Research, gkad1202 (2023)
10.
Zeitschriftenartikel
Wicke, D.; Neumann, P.; Goessringer, M.; Chernev, A.; Davydov, S.; Poehlein, A.; Daniel, R.; Urlaub, H.; Hartmann, R. K.; Ficner, R. et al.; Stuelke, J.: The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis in vitro. Nucleic Acids Research 52 (3), S. 1404 - 1409 (2023)
11.
Zeitschriftenartikel
Jentoft, I. M. A.; Bäuerlein, F. J.B.; Welp, L. M.; Cooper, B. H.; Petrovic, A.; So, C.; Penir, S. M.; Politi, A. Z.; Horokhovskyi, Y.; Takala, I. et al.; Eckel, H.; Moltrecht, R.; Lenart, P.; Cavazza, T.; Liepe, J.; Brose, N.; Urlaub, H.; Fernández-Busnadiego, R.; Schuh, M.: Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Cell 186 (24), S. 5308 - 5327.e25 (2023)
12.
Zeitschriftenartikel
Dreyer, A.; Lenz, C.; Groß, U.; Bohne, W.; Zautner, A.E.: Characterization of Campylobacter jejuni proteome profiles in co-incubation scenarios. Frontiers in Microbiology 14, 1247211 (2023)
13.
Zeitschriftenartikel
Saxena, K.; Roverato, N. D.; Reithmann, M.; Mah, M. M.; Schregle, R.; Schmidtke, G.; Silbern, I.; Urlaub, H.; Aichem, A.: FAT10 is phosphorylated by IKKβ to inhibit the antiviral type-I interferon response. Life science alliance 7 (1), e202101282 (2023)
14.
Zeitschriftenartikel
Chen, Y.; Kokic, G.; Dienemann, C.; Dybkov, O.; Urlaub, H.; Cramer, P.: Structure of the transcribing RNA polymerase II–Elongin complex. Nature Structural & Molecular Biology 30, S. 1925 - 1935 (2023)
15.
Zeitschriftenartikel
Binotti, B.; Ninov, M.; Cepeda, A. P.; Ganzella, M.; Matti, U.; Riedel, D.; Urlaub, H.; Sambandan, S.; Jahn, R.: ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals. Autophagy (2023)
16.
Zeitschriftenartikel
Gruenberger, F.; Schmid, G.; El Ahmad, Z.; Fenk, M.; Vogl, K.; Reichelt, R.; Hausner, W.; Urlaub, H.; Lenz, C.; Grohmann, D.: Uncovering the temporal dynamics and regulatory networks of thermal stress response in a hyperthermophile using transcriptomics and proteomics. mBio 14 (6), e02174-23 (2023)
17.
Zeitschriftenartikel
Alfaro, A. J.; Dittner, C.; Becker, J.; Loft, A.; Mhamane, A.; Maida, A.; Georgiadi, A.; Tsokanos, F.-F.; Klepac, K.; Molocea, C.-E. et al.; El-Merahbi, R.; Motzler, K.; Geppert, J.; Karikari, R. A.; Szendroedi, J.; Feuchtinger, A.; Hofmann, S.; Karaca, S.; Urlaub, H.; Berriel Diaz, M.; Melchior, F.; Herzig, S.: Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism. EMBO Reports 24 (10), e55981| (2023)
18.
Zeitschriftenartikel
Chowdhury, A.; Boshnakovska, A.; Aich, A.; Methi, A.; Vergel Leon, A. M.; Silbern, I.; Lüchtenborg, C.; Cyganek, L.; Prochazka, J.; Sedlacek, R. et al.; Lindovsky, J.; Wachs, D.; Nichtova, Z.; Zudova, D.; Koubkova, G.; Fischer, A.; Urlaub, H.; Brügger, B.; Katschinski, D. M.; Dudek, J.; Rehling, P.: Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome. Embo Molecular Medicine 15 (9), e17399 (2023)
19.
Zeitschriftenartikel
Grahn, E.; Kaufmann, S. V.; Askarova, M.; Ninov, M.; Welp, L. M.; Berger, T.K.; Urlaub, H.; Kaupp, U.B.: Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm. Nature Communications 14, 5395 (2023)
20.
Zeitschriftenartikel
Warth Perez Arias, C. C.; Silbern, I.; Gomes, L. C.; Wartmann, H.; Dambeck, V.; Fanz, J.; Neuenroth, L.; Baehr, M.; Outeiro, T. F.; Bonn, S. et al.; Stadelmann-Nessler, C.; Rizzoli, S. O.; Lenz, C.; Urlaub, H.; Lingor, P.: Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease. Journal of Neurochemistry 166 (5), S. 862 - 874 (2023)
21.
Zeitschriftenartikel
Wolfram-Schauerte, M.; Pozhydaieva, N.; Grawenhoff, J.; Welp, L. M.; Silbern, I.; Wulf, A.; Billau, F. A.; Glatter, T.; Urlaub, H.; Jäschke, A. et al.; Höfer, K.: A viral ADP-ribosyltransferase attaches RNA chains to host proteins. Nature 620, S. 1054 - 1062 (2023)
22.
Zeitschriftenartikel
Garg, G.; Dienemann, C.; Farnung, L.; Schwarz, J.; Linden, A.; Urlaub, H.; Cramer, P.: Structural insights into human co-transcriptional capping. Molecular Cell 83 (14), S. 2464 - 2477.e5 (2023)
23.
Zeitschriftenartikel
Dai, Y.; Ignatyeva, N.; Xu, H.; Wali, R.; Toischer, K.; Brandenburg, S.; Lenz, C.; Pronto, J.; Fakuade, F. E.; Sossalla, S. et al.; Zeisberg, E. M.; Janshoff, A.; Kutschka, I.; Voigt, N.; Urlaub, H.; Rasmussen, T. B.; Mogensen, J.; Lehnart, S. E.; Hasenfuss, G.; Ebert, A.: An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes. Circulation Research 133 (2), S. e19 - e46 (2023)
24.
Zeitschriftenartikel
Witzenberger, M.; Burczyk, S.; Settele, D.; Mayer, W.; Welp, L. M.; Heiss, M.; Wagner, M.; Monecke, T.; Janowski, R.; Carell, T. et al.; Urlaub, H.; Hauck, S. M.; Voigt, A.; Niessing, D.: Human TRMT2A methylates tRNA and contributes to translation fidelity. Nucleic Acids Research, gkad565 (2023)
25.
Zeitschriftenartikel
Nguyen, A.; Lugarini, F.; David, C.; Hosnani, P.; Alagöz, Ç.; Friedrich, A.; Schlütermann, D.; Knotkova, B.; Patel, A.; Parfentev, I. et al.; Urlaub, H.; Meinecke, M.; Stork, B.; Faesen, A. C.: Metamorphic proteins at the basis of human autophagy initiation and lipid transfer. Molecular Cell 83 (12), S. 2077 - 2090.e12 (2023)
26.
Zeitschriftenartikel
Quentin, D.; Schuhmacher, J.S.; Klink, B.U.; Lauer, J.; Shaikh, T.R.; Huis in ’t Veld, P.J.; Welp, L. M.; Urlaub, H.; Zerial, M.; Raunser, S.: Structural basis of mRNA binding by the human FERRY Rab5 effector complex. Molecular Cell 83 (11), S. 1856 - 1871.e9 (2023)
27.
Zeitschriftenartikel
Schmitzová, J.; Cretu, C.; Dienemann, C.; Urlaub, H.; Pena, V.: Structural basis of catalytic activation in human splicing. Nature 617, S. 842 - 850 (2023)
28.
Zeitschriftenartikel
Scheich, S.; Chen, J.; Liu, J.; Schnutgen, F.; Enssle, J. C.; Ceribelli, M.; Thomas, C. J.; Choi, J.; Morris, V.; Hsiao, T. et al.; Nguyen, H.; Wang, B.; Bolomsky, A.; Phelan, J. D.; Corcoran, S.; Urlaub, H.; Young, R. M.; Haupl, B.; Wright, G. W.; Huang, D. W.; Ji, Y.; Yu, X.; Xu, W.; Yang, Y.; Zhao, H.; Muppidi, J.; Pan, K.-T.; Oellerich, T.; Staudt, L. M.: Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas. Cancer Discovery, CD-22-1401 (2023)
29.
Zeitschriftenartikel
Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian Oocytes Store mRNAs in a Mitochondria-Associated Membraneless Compartment. Obstetrical & Gynecological Survey 78 (5), S. 280 - 281 (2023)
30.
Zeitschriftenartikel
Jia, J.; Hilal, T.; Bohnsack, K. E.; Chernev, A.; Tsao, N.; Bethmann, J.; Arumugam, A.; Parmely, L.; Holton, N.; Loll, B. et al.; Mosammaparast, N.; Bohnsack, M. T.; Urlaub, H.; Wahl, M. C.: Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex. Nature Communications 14, 1886 (2023)
31.
Zeitschriftenartikel
Dybkov, O.; Preußner, M.; El Ayoubi, L.; Feng, V.-Y.; Harnisch, C.; Merz, K.; Leupold, P.; Yudichev, P.; Agafonov, D. E.; Will, C. L. et al.; Girard, C.; Dienemann, C.; Urlaub, H.; Kastner, B.; Heyd, F.; Lührmann, R.: Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins. Science Advances 9 (9), eadf178 (2023)
32.
Zeitschriftenartikel
Pörschke, M.; Rodríguez-González, I.; Parfentev, I.; Urlaub, H.; Kehlenbach, R. H.: Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein. Journal of Biological Chemistry 299 (3), 102932 (2023)
33.
Zeitschriftenartikel
Schminke, B.; Kauffmann, P.; Brockmeyer, P.; Miosge, N.; Lenz, C.; Schubert, A.: The Proteomes of Oral Cells Change during Co-Cultivation with Aggregatibacter actinomycetemcomitans and Eikenella corrodens. Biomedicines 11 (3), 700 (2023)
34.
Zeitschriftenartikel
Castro-Hernández, R.; Berulava, T.; Metelova, M.; Epple, R.; Centeno, T. P.; Richter, J.; Kaurani, L.; Pradhan, R.; Sakiba, M. S.; Burkhardt, S. et al.; Ninov, M.; Bohnsack, K. E.; Bohnsack, M. T.; Delalle, I.; Fischer, A.: Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts. Proceedings of the National Academy of Sciences of the United States of America 120 (9), e2204933120 (2023)
35.
Zeitschriftenartikel
Wang, H.; Schilbach, S.; Ninov, M.; Urlaub, H.; Cramer, P.: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nature Structural and Molecular Biology 30, S. 226 - 232 (2023)
36.
Zeitschriftenartikel
Keil, P.; Wulf, A.; Kachariya, N.; Reuscher, S.; Huhn, K.; Silbern, I.; Altmuller, J.; Keller, M.; Stehle, R.; Zarnack, K. et al.; Sattler, M.; Urlaub, H.; Sträßer, K.: Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA. Nucleic Acids Research 51 (2), S. 831 - 851 (2023)
37.
Zeitschriftenartikel
Schoger, E.; Bleckwedel, F.; Germena, G.; Rocha, C.; Tucholla, P.; Sobitov, I.; Möbius, W.; Sitte, M.; Lenz, C.; Samak, M. et al.; Hinkel, R.; Varga, Z. V.; Giricz, Z.; Salinas, G.; Gross, J. C.; Zelarayan, L. C.: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling. Communications Biology 6 (1), 79 (2023)
38.
Zeitschriftenartikel
Franz, A.; Weber, A. I.; Preussner, M.; Dimos, N.; Stumpf, A.; Ji, Y.; Moreno-Velasquez, L.; Voigt, A.; Schulz, F.; Neumann, A. et al.; Kuropka, B.; Kuehn, R.; Urlaub, H.; Schmitz, D.; Wahl, M. C.; Heyd, F.: Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP. Life science alliance 6 (3), e202201826 (2022)
39.
Zeitschriftenartikel
Brás, I. C.; Khani, M. H.; Vasili, E.; Möbius, W.; Riedel, D.; Parfentev, I.; Gerhardt, E.; Fahlbusch, C.; Urlaub, H.; Zweckstetter, M. et al.; Gollisch, T.; Outeiro, T. F.: Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity. Journal of Parkinson's Disease: JPD 12, S. 2397 - 2422 (2022)
40.
Zeitschriftenartikel
Brandenburg, S.; Drews, L.; Schönberger, H.-L.; Jacob, C. F.; Paulke, N. J.; Beuthner, B. E.; Topci, R.; Kohl, T.; Neuenroth, L.; Kutschka, I. et al.; Urlaub, H.; Kück, F.; Leha, A.; Friede, T.; Seidler, T.; Jacobshagen, C.; Toischer, K.; Puls, M.; Hasenfuß, G.; Lenz, C.; Lehnart, S. E.: Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis. Journal of Molecular and Cellular Cardiology (London) 173, S. 1 - 15 (2022)
41.
Zeitschriftenartikel
Giménez, E.; Urlaub, H.; Lockhart, L. J. F.: Photo-tuneable protein nitration by sensitiser tris(bipyridine)-Ruthenium(II) chloride complex. Nitric Oxide - Biology and Chemistry 129 (1), S. 63 - 73 (2022)
42.
Zeitschriftenartikel
Rengachari, S.; Schilbach, S.; Kaliyappan, T.; Gouge, J.; Zumer, K.; Schwarz, J.; Urlaub, H.; Dienemann, C.; Vannini, A.; Cramer, P.: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nature Structural and Molecular Biology 29, S. 1159 - 1169 (2022)
43.
Zeitschriftenartikel
Ditte, Z.; Silbern, I.; Ditte, P.; Urlaub, H.; Eichele, G.: Extracellular vesicles derived from the choroid plexus trigger the differentiation of neural stem cells. Journal of extracellular vesicles 11 (11), 12276 (2022)
44.
Zeitschriftenartikel
Brás, I. C.; Khani, M. H.; Riedel, D.; Parfentev, I.; Gerhardt, E.; van Riesen, C.; Urlaub, H.; Gollisch, T.; Outeiro, T. F.: Ectosomes and exosomes modulate neuronal spontaneous activity. Journal of Proteomics 269, 104721 (2022)
45.
Zeitschriftenartikel
Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment. Science 378 (6617), eabq4835 (2022)
46.
Zeitschriftenartikel
Bolgi, O.; Silva-Garcia, M.; Ross, B.; Pilla, E.; Kari, V.; Killisch, M.; Spitzner, M.; Stark, N.; Lenz, C.; Weiss, K. et al.; Donzelli, L.; Gorrell, M. D.; Grade, M.; Riemer, J.; Urlaub, H.; Dobbelstein, M.; Huber, R.; Geiss-Friedlander, R.: Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair. EMBO Reports 23 (10), e54136 (2022)
47.
Zeitschriftenartikel
Jarausch, J.; Neuenroth, L.; Andag, R.; Leha, A.; Fischer, A.; Asif, A. R.; Lenz, C.; Eidizadeh, A.: Influence of Shear Stress, Inflammation and BRD4 Inhibition on Human Endothelial Cells: A Holistic Proteomic Approach. Cells 11 (19), 3086 (2022)
48.
Zeitschriftenartikel
Stejerean-Todoran, I.; Zimmermann, K.; Gibhardt, C. S.; Vultur, A.; Ickes, C.; Shannan, B.; Rio, Z. B. d.; Wölling, A.; Cappello, S.; Sung, H.-M. et al.; Shumanska, M.; Zhang, X.; Nanadikar, M.; Latif, M. U.; Wittek, A.; Lange, F.; Waters, A.; Brafford, P.; Wilting, J.; Urlaub, H.; Katschinski, D. M.; Rehling, P.; Lenz, C.; Jakobs, S.; Ellenrieder, V.; Roesch, A.; Schön, M. P.; Herlyn, M.; Stanisz, H.; Bogeski, I.: MCU controls melanoma progression through a redox-controlled phenotype switch. EMBO Reports 23, e54746 (2022)
49.
Zeitschriftenartikel
Krebs, T.; Kilic, I.; Neuenroth, L.; Wasselin, T.; Ninov, M.; Tetens, J.; Lenz, C.: A multiplexed parallel reaction monitoring assay to monitor bovine pregnancy-associated glycoproteins throughout pregnancy and after gestation. PLoS One 17 (9), e0271057 (2022)
50.
Zeitschriftenartikel
Linnemannstöns, K.; Karuna M, P.; Witte, L.; Choezom, D.; Honemann-Capito, M.; Lagurin, A. S.; Schmidt, C. V.; Shrikhande, S.; Steinmetz, L.-K.; Möbius, W. et al.; Lenz, C.; Gross, J. C.: Microscopic and biochemical monitoring of endosomal trafficking and extracellular vesicle secretion in an endogenous in vivo model. Journal of extracellular vesicles 11 (9), 12263 (2022)
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