Publikationen

Zeitschriftenartikel (531)

1.
Zeitschriftenartikel
Rodríguez-González, I.; Kohlhause, D.; Lenz, C.; Urlaub, H.; Spillner, C.; Kehlenbach, R. H.: VAPA at the inner nuclear membrane affects nuclear lamins and nuclear morphology. Journal of Cell Science 139 (12), jcs264298 (2026)
2.
Zeitschriftenartikel
Liutkute, A.; Berrandou, T.-E.; Kestel, S.; Schnelle, M.; Dschun, O.; Amedei, H. A.; Neuenroth, L.; Rytkin, E.; Kyshynska, O.; Kensah, G. et al.; El-Essawi, A.; Jebran, A. F.; Danner, B. C.; Baraki, H.; Kutschka, I.; Bremmer, F.; Urlaub, H.; Schmidt, C.; Bouatia-Naji, N.; Efimov, I. R.; Brundel, B. J. J. M.; Lenz, C.; Voigt, N.: Mass spectrometric proteome profiling using a deep spectral library reveals homogenization of right and left atrial proteomes in persistent atrial fibrillation patients. Cardiovascular Research (2026)
3.
Zeitschriftenartikel
Wegener, J. B.; Zuhlke, Y.; Fleischhacker, C.; Marks, J.; Foo, B.; Bader, N.; Riedemann, G. C.; Wedemeyer, J.; Vu, K.-C.; Leon, A. M. V. et al.; Paulke, N. J.; Kohl, T.; Urlaub, H.; Schmidt, C.; Hasenfuss, G.; Moser, T.; Rog-Zielinska, E. A.; Lenz, C.; Lehnart, S. E.; Brandenburg, S.: Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction. Scientific Reports 16, 10488 (2026)
4.
Zeitschriftenartikel
Thomé, C. C.; Lemus-Diaz, N.; Bloch von Blottnitz, K. I.; Tagnères, S.; Klein Helmkamp, M.; Honemann-Capito, M.; Hackert, P.; Moshkovskii, S.; Lenz, C.; Bohnsack, M. T. et al.; Urlaub, H.; Bohnsack, K. E.: Distinct steps of nuclear maturation of human pre-60S complexes require the activity of GTPases including GNL3L. Nucleic Acids Research 54 (5) (2026)
5.
Zeitschriftenartikel
Kanzow, P.; Lenz, C.; Schlarmann, F.; Barke, S.; Rohland, B.; Schmidt, A.; Gorshkova, A.; Neuenroth, L.; Wiegand, A.: Saliva and salivary pellicle composition and proteomic profile in smokers vs. non-smokers and its effect on dental erosion. Journal of Dentistry 166, 106517 (2026)
6.
Zeitschriftenartikel
Neumann, P.; Dybkov, O.; Urlaub, H.; Ficner, R.; Dickmanns, A.: Alphafold 3-guided insights into the Importinβ: Importin7 heterodimer interaction and its binding to histone H1. Structure 34 (3), S. 414 - 425.e4 (2026)
7.
Zeitschriftenartikel
Imad, H.; Strange, K. E.; Dianzani, C.; Soh, W. T.; Siddons, S.; Kordasti, S.; Gigliotti, C. L.; Chiocchetti, A.; Urlaub, H.; Nott, T. J. et al.; Dianzani, U.; Liepe, J.; Mishto, M.: OPN-Derived Peptides Generated by Proteasomes Can Promote Cell Migration via CD44 Activation. Journal of Immunology Research 2026, 2726052 (2026)
8.
Zeitschriftenartikel
Kohlhause, D.; Spillner, C.; Zapata, V. A.; Lenz, C.; Urlaub, H.; Kohl, T.; Lehnart, S. E.; Gerace, L.; Kehlenbach, R. H.: The nuclear envelope protein TMEM209 is an integral component of the nuclear pore complex and interacts with Nup210. Journal of Cell Science 139 (12), jcs264534 (2026)
9.
Zeitschriftenartikel
Machado de Amorim, A.; Xue, G.; He, W.; Dittmers, T.; Lewandowski, S.; Perez-Borrajero, C.; Bethmann, J.; Mateva, N.; Krage, C.; Nandana, V. et al.; Loll, B.; Hilal, T.; Hennig, J.; Urlaub, H.; Marzluff, W. F.; Chakrabarti, S.: Mechanistic insights into recruitment and regulation of the RNA helicase UPF1 in replication-dependent histone mRNA decay. Nature Communications 17, 155 (2026)
10.
Zeitschriftenartikel
Auvray, M.; Koenen, T.; Dybkov, O.; Urlaub, H.; Lukinavičius, G.: Biocompatible sulfonium-based covalent probes for endogenous tubulin fluorescence nanoscopy in live and fixed cells. Nature Communications 16, 11107 (2025)
11.
Zeitschriftenartikel
Rathore, S.; Conrad, J.; De Silva, D.; Ferrari, A.; Bouquio, D.; Kim, H.-J.; Salvatori, R.; Linden, A.; Dybkov, O.; Urlaub, H. et al.; Ott, M.; Barrientos, A.: The late stages of yeast mitoribosome large subunit biogenesis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1872 (8), 120051 (2025)
12.
Zeitschriftenartikel
Ghosh Dastidar, N.; Freyer, N. S.; Petrychenko, V.; de A. P. Schwarzer, A. C.; Peng, B.-Z.; Samatova, E.; Kothe, C.; Schmidt, M.; Peske, F.; Politi, A. Z. et al.; Urlaub, H.; Fischer, N.; Rodnina, M. V.; Wohlgemuth, I.: Selective silencing of antibiotic-tethered ribosomes as a resistance mechanism against aminoglycosides. Nature Communications 16, 9568 (2025)
13.
Zeitschriftenartikel
Walshe, J. L.; Ochmann, M.; Neef, U.; Dybkov, O.; Dienemann, C.; Oberthür, C.; Zheenbekova, A.; Urlaub, H.; Cramer, P.: Molecular mechanism of co-transcriptional H3K36 methylation by SETD2. Nature Communications 16, 9565 (2025)
14.
Zeitschriftenartikel
Avilov, I.; Horokhovskyi, Y.; Mehta, P.; Welp, L.; Jakobi, J.; Cai, M.; Orzechowski, A.; Urlaub, H.; Liepe, J.; Lenart, P.: Phosphoproteomic identification of Mos–MAPK targets in meiotic cell cycle and asymmetric oocyte divisions. Journal of Cell Biology 224 (12), e202312140 (2025)
15.
Zeitschriftenartikel
Reshetniak, S.; Bogaciu, C. A.; Bonn, S.; Brose, N.; Cooper, B. H.; D'Este, E.; Fauth, M.; Fernández‐Busnadiego, R.; Fiosins, M.; Fischer, A. et al.; Georgiev, S. V.; Jakobs, S.; Klumpp, S.; Köster, S.; Lange, F.; Lipstein, N.; Macarrón‐Palacios, V.; Milovanovic, D.; Moser, T.; Müller, M.; Opazo, F.; Outeiro, T. F.; Pape, C.; Priesemann, V.; Rehling, P.; Salditt, T.; Schlüter, O.; Simeth, N.; Steinem, C.; Tchumatchenko, T.; Tetzlaff, C.; Tirard, M.; Urlaub, H.; Wichmann, C.; Wolf, F.; Rizzoli, S. O.: The synaptic vesicle cluster as a controller of pre‐ and postsynaptic structure and function. The Journal of Physiology 603 (20), S. 5935 - 5964 (2025)
16.
Zeitschriftenartikel
Fokkens, T. J.; Rauh, E. T.; Wolter, M.; Sebald, H.; Mitnacht, M.; Ainatzi, S.; Sprick, S.; Teschke, L.; Eisenhuth, N.; Huibregtse, J. M. et al.; Butter, F.; Urlaub, H.; Karnkowska, A.; Steinchen, W.; Schleicher, U.; Janzen, C. J.; Lorenz, S.: A Leishmania virulence factor harnesses an allosteric kinase switch to regulate its ubiquitin ligase activity. Molecular Cell 85 (19), S. 3711 - 3728.e11 (2025)
17.
Zeitschriftenartikel
Orth, B.; Pohl, P.; Aust, F.; Ji, Y.; Seenivasan, A.; Dybkov, O.; Liang, X. J.; Bock, L.; Leidner, F.; Levantovsky, S. et al.; Schardey, P.; Sander, P.; Disch, N. J.; Trautz, M. L.; Mizi, A.; Papantonis, A.; Lenz, C.; Grubmüller, H.; Steinchen, W.; Behrends, C.; Urlaub, H.; Gehringer, M.; Lorenz, S.: Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1. Nature Communications 16, 8182 (2025)
18.
Zeitschriftenartikel
Scholl, L.-S.; Demleitner, A. F.; Riedel, J.; Adachi, S.; Neuenroth, L.; Meijs, C.; Tzeplaeff, L.; Caldi Gomes, L.; Galhoz, A.; Cordts, I. et al.; Lenz, C.; Menden, M.; Lingor, P.: Identification and validation of a tear fluid-derived protein biomarker signature in patients with amyotrophic lateral sclerosis. Acta Neuropathologica Communications 13, 187 (2025)
19.
Zeitschriftenartikel
Fenech, E. J.; Kupervaser, M.; Boshnakovska, A.; Ravid, S.; Castro, I. G.; Asraf, Y.; Callegari, S.; Lenz, C.; Urlaub, H.; Rehling, P. et al.; Schuldiner, M.: Profiling the LAM Family of Contact Site Tethers Provides Insights into Their Regulation and Function. Contact 8, S. 1 - 17 (2025)
20.
Zeitschriftenartikel
Welp, L. M.; Wulf, A.; Chernev, A.; Horokhovskyi, Y.; Moshkovskii, S.; Dybkov, O.; Neumann, P.; Pašen, M.; Siraj, A.; Raabe, M. et al.; Göthert, H.; Walshe, J.; Infante, D. A.; de A P Schwarzer, A.; Dickmanns, A.; Johannsson, S.; Schmitzová, J.; Wohlgemuth, I.; Netz, E.; He, Y.; Fritzemeier, K.; Delanghe, B.; Viner, R.; Vos, S.; Oberbeckmann, E.; Bohnsack, K.; Bohnsack, M.; Cramer, P.; Ficner, R.; Kohlbacher, O.; Liepe, J.; Sachsenberg, T.; Urlaub, H.: Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid–protein interaction sites by mass spectrometry. Nucleic Acids Research 53 (15), gkaf727 (2025)
21.
Zeitschriftenartikel
Zheenbekova, A.; Walshe, J. L.; Ochmann, M.; Bäuerle, M.; Neef, U.; Maier, K. C.; Rus, P.; Yan, Y.; Urlaub, H.; Cramer, P. et al.; Žumer, K.: IWS1 positions downstream DNA to globally stimulate Pol II elongation. Nature Communications 16, 7747 (2025)
22.
Zeitschriftenartikel
Grune, J.; Lenz, C.; Cochain, C.; Momin, N.: More than myocytes: The heart's electrical ensemble. The Journal of Physiology (2025)
23.
Zeitschriftenartikel
Cretu, C.; Chernev, A.; Szabó, C. Z. K.; Pena, V.; Urlaub, H.; Moser, T.; Preobraschenski, J.: Structural insights into lipid membrane binding by human ferlins. The EMBO Journal 44 (14), S. 3926 - 3958 (2025)
24.
Zeitschriftenartikel
Urbach, L.; Wieland, L.; Penz, F.; Samuel, R. D.; Küffer, S.; Klein, L.; Lenz, C.; Sax, U.; Ghadimi, M.; Schulz-Heddergott, R. et al.; Hessmann, E.; Ellenrieder, V.; Dusetti, N.; Singh, S. K.: TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer. Science Advances 11 (27), eadu2339 (2025)
25.
Zeitschriftenartikel
Boshnakovska, A.; Pronto, J. R.; Gall, T.; Aich, A.; Prochazka, J.; Nichtova, Z.; Sedlacek, R.; Sobitov, I.; Ainatzi, S.; Lenz, C. et al.; Katschinski, D. M.; Urlaub, H.; Voigt, N.; Rehling, P.; Kremer, L. S.: SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart. Cell Reports 44 (6), 115723 (2025)
26.
Zeitschriftenartikel
Güran, A.; Ji, Y.; Fang, P.; Pan, K.-T.; Urlaub, H.; Avkiran, M.; Lenz, C.; Weeks, K. L.: PP2A-B56α is a key determinant of cardiac protein phosphorylation and functional responses to β-adrenergic signalling. Journal of Molecular and Cellular Cardiology Plus 12, 100301 (2025)
27.
Zeitschriftenartikel
Soni, K.; Horvath, A.; Dybkov, O.; Schwan, M.; Trakansuebkul, S.; Flemming, D.; Wild, K.; Urlaub, H.; Fischer, T.; Sinning, I.: Structures of aberrant spliceosome intermediates on their way to disassembly. Nature Structural & Molecular Biology 32, S. 914 - 925 (2025)
28.
Zeitschriftenartikel
Choezom, D.; Plum, J.-M.; Karuna M, P.; Danieli-Mackay, A.; Lenz, C.; Brockmeyer, P.; Gross, J. C.: The Ceramide-Dependent EV Secretome Differentially Affects Prostate Cancer Cell Migration. Cells 14 (7), 547 (2025)
29.
Zeitschriftenartikel
Ainatzi, S.; Kaufmann, S. V.; Silbern, I.; Georgiev, S. V.; Lorenz, S.; Rizzoli, S. O.; Urlaub, H.: Ca2+-triggered (de)ubiquitination events in synapses. Molecular & Cellular Proteomics 24 (4), 100946 (2025)
30.
Zeitschriftenartikel
Cormican, J. A.; Medfai, L.; Wawrzyniuk, M.; Pašen, M.; Afrache, H.; Fourny, C.; Khan, S.; Gneiße, P.; Soh, W. T.; Timelli, A. et al.; Nolfi, E.; Pannekoek, Y.; Cope, A.; Urlaub, H.; Sijts, A. J.A. M.; Mishto, M.; Liepe, J.: PEPSeek-mediated identification of novel epitopes from viral and bacterial pathogens and the impact on host cell immunopeptidomes. Molecular & Cellular Proteomics 24 (4), 100937 (2025)
31.
Zeitschriftenartikel
Gobran, M.; Politi, A. Z.; Welp, L. M.; Jakobi, J.; Urlaub, H.; Lenart, P.: PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division. The EMBO Journal 44 (7), S. 1891 - 1920 (2025)
32.
Zeitschriftenartikel
Sala, F. A.; Ditter, K.; Dybkov, O.; Urlaub, H.; Hillen, H. S.: Structural basis of Nipah virus RNA synthesis. Nature Communications 16, 2261 (2025)
33.
Zeitschriftenartikel
Fendler, N. L.; Ly, J.; Welp, L. M.; Lu, D.; Schulte, F.; Urlaub, H.; Vos, S. M.: Identification and characterization of a human MORC2 DNA binding region that is required for gene silencing. Nucleic Acids Research 53 (4), gkae1273 (2025)
34.
Zeitschriftenartikel
Sailer, A.-L.; Brendel, J.; Chernev, A.; König, S.; Bischler, T.; Gräfenhan, T.; Urlaub, H.; Gophna, U.; Marchfelder, A.: Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system. Frontiers in Microbiology 16, 1543464 (2025)
35.
Zeitschriftenartikel
Jennrich, J.; Farkas, Á.; Urlaub, H.; Schwappach, B.; Bohnsack, K. E.: The formation of chaperone-rich GET bodies depends on the tetratricopeptide repeat region of Sgt2 and is reversed by NADH. Journal of Cell Science 138 (6), jcs263616 (2025)
36.
Zeitschriftenartikel
Yousefi, R.; Cruz-Zaragoza, L.D.; Valpadashi, A.; Hansohn, C.; Dahal, D.; Richter-Dennerlein, R.; Rizzoli, S.; Urlaub, H.; Rehling, P.; Pacheu-Grau, D.: A microscopy-based screen identifies cellular kinases modulating mitochondrial translation. Cell Reports 44 (1), 115143 (2025)
37.
Zeitschriftenartikel
Di Cianni, N.; Bolsinger, S.; Brendel, J.; Raabe, M.; König, S.; Mitchell, L.; Bischler, T.; Gräfenhan, T.; Read, C.; Erdmann, S. et al.; Allers, T.; Walther, P.; Urlaub, H.; Dyall-Smith, M.; Pfeiffer, F.; Marchfelder, A.: Provirus deletion from Haloferax volcanii affects motility, stress resistance, and CRISPR RNA expression. microLife 6, uqaf008 (2025)
38.
Zeitschriftenartikel
Xylaki, M.; Chopra, A.; Kyriachenko, Y.; Scherer, J.; Otte, B.; Dakna, M.; Bartl, M.; Weber, S.; Schade, S.; Lenz, C. et al.; Mollenhauer, B.: Proteomic Exploration of L1CAM+-Extracellular Vesicles from Plasma of Manifest and Prodromal Parkinson’s Disease. International Journal of Molecular Sciences 26 (23), 11564 (2025)
39.
Zeitschriftenartikel
Hollstein, M. M.; Traidl, S.; Heetfeld, A.; Forkel, S.; Leha, A.; Alkon, N.; Ruwisch, J.; Lenz, C.; Schön, M. P.; Schmelz, M. et al.; Brunner, P.; Steinhoff, M.; Buhl, T.: Skin microdialysis detects distinct immunologic patterns in chronic inflammatory skin diseases. The Journal of Allergy and Clinical Immunology 154 (6), S. 1450 - 1461 (2024)
40.
Zeitschriftenartikel
Lavdovskaia, E.; Hanitsch, E.; Linden, A.; Pašen, M.; Challa, V.; Horokhovskyi, Y.; Roetschke, H. P.; Nadler, F.; Welp, L.; Steube, E. et al.; Heinrichs, M.; Mai, M. M.-Q.; Urlaub, H.; Liepe, J.; Richter-Dennerlein, R.: A roadmap for ribosome assembly in human mitochondria. Nature Structural & Molecular Biology 31, S. 1898 - 1908 (2024)
41.
Zeitschriftenartikel
Swarnkar, A.; Leidner, F.; Rout, A. K.; Ainatzi, S.; Schmidt, C. C.; Becker, S.; Urlaub, H.; Griesinger, C.; Grubmüller, H.; Stein, A.: Determinants of chemoselectivity in ubiquitination by the J2 family of ubiquitin-conjugating enzymes. The EMBO Journal 43 (24), S. 6705 - 6739 (2024)
42.
Zeitschriftenartikel
Altas, B.; Tuffy, L. P.; Patrizi, A.; Dimova, K.; Soykan, T.; Brandenburg, C.; Romanowski, A. J.; Whitten, J. R.; Robertson, C. D.; Khim, S. N. et al.; Crutcher, G. W.; Ambrozkiewicz, M.; Yagensky, O.; Krüger-Burg, D. D.; Hammer, M.; Hsiao, H.-H.; Laskowski, P. R.; Dyck, L.; Puche, A. C.; Sassoè-Pognetto, M.; Chua, J. J. E.; Urlaub, H.; Jahn, O.; Brose, N.; Poulopoulos, A.: Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses. Biological Psychiatry 96 (10), S. 815 - 828 (2024)
43.
Zeitschriftenartikel
Foo, B.; Amedei, H.; Kaur, S.; Jaawan, S.; Boshnakovska, A.; Gall, T.; de Boer, R. A.; Silljé, H. H. W.; Urlaub, H.; Rehling, P. et al.; Lenz, C.; Lehnart, S. E.: Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts. PLOS ONE 19 (10), e0311203 (2024)
44.
Zeitschriftenartikel
Fokken, C.; Silbern, I.; Shomroni, O.; Pan, K.-T.; Ryazanov, S.; Leonov, A.; Winkler, N.; Urlaub, H.; Griesinger, C.; Becker, D.: Interfering with aggregated α-synuclein in advanced melanoma leads to a major upregulation of MHC class II proteins. Melanoma Research 34 (5), S. 393 - 407 (2024)
45.
Zeitschriftenartikel
Lahiri, S. K.; Lu, J.; Aguilar-Sanchez, Y.; Li, H.; Moreira, L. M.; Hulsurkar, M. M.; Mendoza, A.; Turkieltaub Paredes, M. R.; Navarro-Garcia, J. A.; Munivez, E. et al.; Horist, B.; Moore, O. M.; Weninger, G.; Brandenburg, S.; Lenz, C.; Lehnart, S. E.; Sayeed, R.; Krasopoulos, G.; Srivastava, V.; Zhang, L.; Karch, J. M.; Reilly, S.; Wehrens, X. H.T.: Targeting calpain-2-mediated junctophilin-2 cleavage delays heart failure progression following myocardial infarction. Journal of Molecular and Cellular Cardiology 194, S. 85 - 95 (2024)
46.
Zeitschriftenartikel
Sailer, A.-L.; Jevtic, Z.; Stoll, B.; Wörtz, J.; Sharma, K.; Urlaub, H.; Dyall-Smith, M.; Pfeiffer, F.; Marchfelder, A.; Lenz, C.: Iron starvation results in up-regulation of a probable Haloferax volcanii siderophore transporter. Frontiers in Microbiology 15, 1422844 (2024)
47.
Zeitschriftenartikel
Aich, A.; Boshnakovska, A.; Witte, S.; Gall, T.; Unthan-Fechner, K.; Yousefi, R.; Chowdhury, A.; Dahal, D.; Methi, A.; Kaufmann, S. et al.; Silbern, I.; Prochazka, J.; Nichtova, Z.; Palkova, M.; Raishbrook, M.; Koubkova, G.; Sedlacek, R.; Tröder, S.E.; Zevnik, B.; Riedel, D.; Michanski, S.; Möbius, W.; Ströbel, P.; Lüchtenborg, C.; Giavalisco, P.; Urlaub, H.; Fischer, A.; Brügger, B.; Jakobs, S.; Rehling, P.: Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Nature Communications 15, 6914 (2024)
48.
Zeitschriftenartikel
Amedei, H.; Paul, N. B.; Foo, B.; Neuenroth, L.; Lehnart, S. E.; Urlaub, H.; Lenz, C.: mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes. Frontiers in Analytical Science 4, 1425190 (2024)
49.
Zeitschriftenartikel
Bilger, R.; Migur, A.; Wulf, A.; Steglich, C.; Urlaub, H.; Hess, W. R.: A type III-Dv CRISPR-Cas system is controlled by the transcription factor RpaB and interacts with the DEAD-box RNA helicase CrhR. Cell Reports 43 (7), 114485 (2024)
50.
Zeitschriftenartikel
Zhang, Z.; Kumar, V.; Dybkov, O.; Will, C. L.; Zhong, J.; Ludwig, S. E. J.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature 630, S. 1012 - 1019 (2024)
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