Max-Planck-Institut für Multidisziplinäre Naturwissenschaften

Publikationen

Zeitschriftenartikel (389)

1.

Zeitschriftenartikel

Upmanyu, N.; Jin, J.; Emde, H. v. d.; Ganzella, M.; Bösche, L.; Malviya, V. N.; Zhuleku, E.; Politi, A. Z.; Ninov, M.; Silbern, I. et al.; Leutenegger, M.; Urlaub, H.; Riedel, D.; Preobraschenski, J.; Milosevic, I.; Hell, S. W.; Jahn, R.; Sambandan, S.: Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3. Neuron, In Press (2022)

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Georgiou, M.; Yang, C.; Atkinson, R.; Pan, K.‐.; Buskin, A.; Molina, M. M.; Collin, J.; Al‐Aama, J.; Goertler, F.; Ludwig, S. E. J. et al.; Davey, T.; Lührmann, R.; Nagaraja‐Grellscheid, S.; Johnson, C. A.; Ali, R.; Armstrong, L.; Korolchuk, V.; Urlaub, H.; Mozaffari‐Jovin, S.; Lako, M.: Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient‐induced pluripotent stem cell‐derived retinal pigment epithelium cells. Clinical and Translational Medicine 12 (3), e759 (2022)

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3.

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Mishto, M.; Horokhovskyi, Y.; Cormican, J. A.; Yang, X.; Lynham, S.; Urlaub, H.; Liepe, J.: Database search engines and target database features impinge upon the identification of post‐translationally cis‐spliced peptides in HLA class I immunopeptidomes. Proteomics, In Press; 2100226 (2022)

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4.

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James, C.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Sequestosome 1 is part of the interaction network of VAPB. International Journal of Molecular Sciences 22 (24), 13271 (2021)

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5.

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Güran, A.; Ji, Y.; Fang, P.; Pan, K.-T.; Urlaub, H.; Avkiran, M.; Lenz, C.: Quantitative analysis of the cardiac phosphoproteome in response to acute β-adrenergic receptor stimulation in vivo. International Journal of Molecular Sciences 22 (22), 12584 (2021)

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6.

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Fianu, I.; Chen, Y.; Dienemann, C.; Dybkov, O.; Linden, A.; Urlaub, H.; Cramer, P.: Structural basis of Integrator-mediated transcription regulation. Science 374 (6569), S. 883 - 887 (2021)

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7.

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Cruz-Zaragoza, L. D.; Dennerlein, S.; Linden, A.; Yousefi, R.; Lavdovskaia, E.; Aich, A.; Falk, R. R.; Gomkale, R.; Schöndorf, T.; Bohnsack, M. T. et al.; Richter-Dennerlein, R.; Urlaub, H.; Rehling, P.: An in vitro system to silence mitochondrial gene expression. Cell 184 (23), S. 5824 - 5837.e15 (2021)

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8.

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Aquino, G. R. R.; Hackert, P.; Krogh, N.; Pan, K. T.; Jaafar, M.; Henras, A. K.; Nielsen, H.; Urlaub, H.; Bohnsack, K. E.; Bohnsack, M. T.: The RNA helicase Dbp7 promotes domain V/VI compaction and stabilization of inter-domain interactions during early 60S assembly. Nature Communications 12, 6152 (2021)

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9.

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Kokic, G.; Wagner, F. R.; Chernev, A.; Urlaub, H.; Cramer, P.: Structural basis of human transcription–DNA repair coupling. Nature 598 (7880), S. 368 - 372 (2021)

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10.

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Gomkale, R.; Linden, A.; Neumann, P.; Schendzielorz, A. B.; Stoldt, S.; Dybkov, O.; Kilisch, M.; Schulz, C.; Cruz-Zaragoza, L. D.; Schwappach, B. et al.; Ficner, R.; Jakobs, S.; Urlaub, H.; Rehling, P.: Mapping protein interactions in the active TOM-TIM23 supercomplex. Nature Communications 12, 5715 (2021)

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11.

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Zhang, Z.; Rigo, N.; Dybkov, O.; Fourmann, J. B.; Will, C. L.; Kumar, V.; Urlaub, H.; Stark, H.; Lührmann, R.: Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature 596 (7871), S. 296 - 300 (2021)

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12.

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Helm, M. S.; Dankovich, T. M.; Mandad, S.; Rammner, B.; Jähne, S.; Salimi, V.; Koerbs, C.; Leibrandt, R.; Urlaub, H.; Schikorski, T. et al.; Rizzoli, S. O.: A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines. Nature Neuroscience 24 (8), S. 1151 - 1162 (2021)

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13.

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Chen, Y.; Vos, S. M.; Dienemann, C.; Ninov, M.; Urlaub, H.; Cramer, P.: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 81 (16), S. 3386 - 3399.e10 (2021)

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14.

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Fang, P.; Ji , Y.; Silbern, I.; Viner, R.; Oellerich, T.; Pan, K. T.; Urlaub, H.: Evaluation and optimization of high-field asymmetric waveform ion-mobility spectrometry for multiplexed quantitative site-specific N-glycoproteomics. Analytical Chemistry 93 (25), S. 8846 - 8855 (2021)

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15.

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Martinez Hernandez, A.; Silbern, I.; Geffers, I.; Tatenhorst, L.; Becker, S.; Urlaub, H.; Zweckstetter, M.; Griesinger, C.; Eichele, G.: Low-Expressing synucleinopathy mouse models based on oligomer-forming mutations and C-terminal truncation of α-synuclein. Frontiers in Neuroscience 15, 643391 (2021)

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16.

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Hillen, H. S.; Lavdovskaia, E.; Nadler, F.; Hanitsch, E.; Linden, A.; Bohnsack, K. E.; Urlaub, H.; Richter-Dennerlein, R.: Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling. Nature Communications 12, 3672 (2021)

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17.

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Yildirim, A.; Mozaffari-Jovin, S.; Wallisch, A. K.; Schäfer, J.; Ludwig, S. E. J.; Urlaub, H.; Lührmann, R.; Wolfrum, U.: SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes. Nucleic Acids Research 49 (10), S. 5845 - 5866 (2021)

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18.

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Osman, S.; Mohammad, E.; Lidschreiber, M.; Stuetzer, A.; Bazsó, F. L.; Maier, K. C.; Urlaub, H.; Cramer, P.: The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 296, 100734 (2021)

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19.

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Wensien, M.; Rabe von Pappenheim, F.; Funk, L. M.; Kloskowski, P.; Curth, U.; Diederichsen, U.; Uranga, J.; Ye, J.; Fang, P.; Pan, K. T. et al.; Urlaub, H.; Mata, R. A.; Sautner, V.; Tittmann, K.: A lysine–cysteine redox switch with an NOS bridge regulates enzyme function. Nature 593 (7859), S. 460 - 464 (2021)

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20.

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Hallumi, E.; Shalah, R.; Lo, W. L.; Corso, J.; Oz, I.; Beach, D.; Wittman, S.; Isenberg, A.; Sela, M.; Urlaub, H. et al.; Weiss, A.; Yablonski, D.: Itk promotes the integration of TCR and CD28 costimulation through its direct substrates SLP-76 and Gads. The Journal of Immunology 206 (10), S. 2322 - 2337 (2021)

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21.

Zeitschriftenartikel

Naarman-de Vries, I. S.; Senatore, R.; Moritz, B.; Marx, G.; Urlaub, H.; Niessing, D.; Ostareck, D. H.; Ostareck-Lederer, A.: Methylated HNRNPK acts on RPS19 to regulate ALOX15 synthesis in erythropoiesis. Nucleic Acids Research 49 (6), S. 3507 - 3523 (2021)

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22.

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Wohlgemuth, I.; Garofalo, R.; Samatova, E. N.; Günenç, A. N.; Lenz, C.; Urlaub, H.; Rodnina, M. V.: Translation error clusters induced by aminoglycoside antibiotics. Nature Communications 12, 1830 (2021)

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23.

Zeitschriftenartikel

Yatsenko, A. S.; Kucherenko, M. M.; Xie, Y.; Urlaub, H.; Shcherbata, H. R.: Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization. eLife 10, e63868 (2021)

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24.

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Zheng, X.; Zhang, L.; Kuang, Y.; Venkataramani, V.; Jin, F.; Hein, K.; Zafeiriou, M. P.; Lenz, C.; Moebius, W.; Kilic, E. et al.; Hermann, D. M.; Weber, M. S.; Urlaub, H.; Zimmermann, W.-H.; Bähr, M.; Doeppner, T. R.: Extracellular vesicles derived from neural progenitor cells: A preclinical evaluation for stroke treatment in mice. Translational Stroke Research 12 (1), S. 185 - 203 (2021)

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25.

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Valpadashi, A.; Callegari, S.; Linden, A.; Neumann, P.; Ficner, R.; Urlaub, H.; Deckers, M.; Rehling, P.: Defining the architecture of the human TIM22 complex by chemical crosslinking. FEBS Letters 595 (2), S. 157 - 168 (2021)

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26.

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Kraxner, J.; Lorenz, C.; Menzel, J.; Parfentev, I.; Silbern, I.; Denz, M.; Urlaub, H.; Schwappach, B.; Köster, S.: Post-translational modifications soften vimentin intermediate filaments. Nanoscale 13 (1), S. 380 - 387 (2021)

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27.

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Blersch, K. F.; Burchert, J.-P.; August, S.-C.; Welp, L.; Neumann, P.; Köster, S.; Urlaub, H.; Ficner, R.: Structural model of the M7G46 methyltransferase TrmB in complex with tRNA. RNA Biology 18 (12), S. 2466 - 2479 (2021)

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28.

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Silbern, I.; Pan, K. T.; Fiosins, M.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.; Urlaub, H.; Jahn, R.: Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling. Molecular and Cellular Proteomics 20, 100061 (2021)

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29.

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Townsend, C.; Leelaram, M. N.; Agafonov, D. E.; Dybkov, O.; Will, C. L.; Bertram, K.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science 370 (6523), eabc3753 (2020)

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30.

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Lavdovskaia, E.; Denks, K.; Nadler, F.; Steube, E.; Linden, A.; Urlaub, H.; Rodnina, M. V.; Richter-Dennerlein, R.: Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. Nucleic Acids Research 48 (22), S. 12929 - 12942 (2020)

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31.

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Netz, E.; Dijkstra, T. M. H.; Sachsenberg, T.; Zimmermann, L.; Walzer, M.; Monecke, T.; Ficner, R.; Dybkov, O.; Urlaub, H.; Kohlbacher, O.: OpenPepXL: An open-source tool for sensitive identification of cross-linked peptides in XL-MS. Molecular and Cellular Proteomics 19 (12), S. 2157 - 2167 (2020)

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32.

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Leitner, A.; Bonvin, A. M. J. J.; Borchers, C. H.; Chalkley, R. J.; Chamot-Rooke, J.; Combe, C. W.; Cox, J.; Dong, M.-Q.; Fischer, L.; Götze, M. et al.; Gozzo, F. C.; Heck, A. J. R.; Hoopmann, M. R.; Huang, L.; Ishihama, Y.; Jones, A. R.; Kalisman, N.; Kohlbacher, O.; Mechtler, K.; Moritz, R. L.; Netz, E.; Novak, P.; Petrotchenko, E.; Sali, A.; Scheltema, R. A.; Schmidt, C.; Schriemer, D.; Sinz, A.; Sobott, F.; Stengel, F.; Thalassinos, K.; Urlaub, H.; Viner, R.; Vizcaíno, J. A.; Wilkins, M. R.; Rappsilber, J.: Toward increased reliability, transparency, and accessibility in cross-linking mass spectrometry. Structure 28 (11), S. 1259 - 1268 (2020)

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33.

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Fish, K.; Comoglio, F.; Shaffer, A. L.; Jia, Y.; Pan, K. T.; Scheich, S.; Oellerich, A.; Doebele, C.; Ikeda, M.; Schaller, S. J. et al.; Nguyen, H.; Muppidi, J.; Wright, G. W.; Urlaub, H.; Serve, H.; Staudtd, L. M.; Longnecker, R.; Oellerich, T.: Rewiring of B cell receptor signaling by Epstein–Barr virus LMP2A. Proceedings of the National Academy of Sciences of the USA 117 (42), S. 26318 - 26327 (2020)

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34.

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Liess, A. K. L.; Kucerova, A.; Schweimer, K.; Schlesinger, D.; Dybkov, O.; Urlaub, H.; Mansfeld, J.; Lorenz, S.: Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. Science Signaling 13 (654), eaba8208 (2020)

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35.

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Stützer, A.; Welp, L.; Raabe, M.; Sachsenberg, T.; Kappert, C.; Wulf, A.; Lau, A. M.; David, S.-S.; Chernev, A.; Kramer, K. et al.; Politis, A.; Kohlbacher, O.; Fischle, W.; Urlaub, H.: Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry. Nature Communications 11, 5250 (2020)

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36.

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Bertram, K.; El Ayoubi, L.; Dybkov, O.; Agafonov, D.; Will, C. L.; Hartmuth, K.; Urlaub, H.; Kastner, B.; Stark, H.; Lührmann, R.: Structural insights into the roles of metazoan-specific splicing factors in the human step 1 spliceosome. Molecular Cell 80 (1), S. 127 - 139.e6 (2020)

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37.

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Vahsen, B. F.; Ribas, V. T.; Sundermeyer, J.; Boecker, A.; Dambeck, V.; Lenz, C.; Shomroni, O.; Gomes, L. C.; Tatenhorst, L.; Barski, E. et al.; Roser, A.-E.; Michel, U.; Urlaub, H.; Salinas, G.; Bähr, M.; Koch, J. C.; Lingor, P.: Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. Cell Death and Differentiation 27 (10), S. 2810 - 2827 (2020)

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38.

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Menzel, J.; Kownatzki-Danger, D.; Tokar, S.; Ballone, A.; Unthan-Fechner, K.; Kilisch, M.; Lenz, C.; Urlaub, H.; Mori, M.; Ottmann, C. et al.; Shattock, M. J.; Lehnart, S. E.; Schwappach, B.: 14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban. Science Signaling 13 (647), eaaz1436 (2020)

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39.

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Ukmar-Godec, T.; Fang, P.; Ibáñez de Opakua, A.; Henneberg, F.; Godec, A.; Pan, K. T.; Cima-Omori, M.-S.; Chari, A.; Mandelkow, E.; Urlaub, H. et al.; Zweckstetter, M.: Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 6 (30), eaba3916 (2020)

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supplementary-material

40.

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Zhang, Z.; Will, C. L.; Bertram, K.; Dybkov, O.; Hartmuth, K.; Agafonov, D. E.; Hofele, R. V.; Urlaub, H.; Kastner, B.; Lührmann, R. et al.; Stark, H.: Molecular architecture of the human 17S U2 snRNP. Nature 583 (7815), S. 310 - 313 (2020)

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41.

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Königsmann, T.; Parfentev, I.; Urlaub, H.; Riedel, D.; Schuh, R.: The bicistronic gene würmchen encodes two essential components for epithelial development in Drosophila. Developmental Biology 463 (1), S. 53 - 62 (2020)

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42.

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Linden, A.; Deckers, M.; Parfentev, I.; Pflanz, R.; Homberg, B.; Neumann, P.; Ficner, R.; Rehling, P.; Urlaub, H.: A Cross-linking mass spectrometry approach defines protein interactions in yeast mitochondria. Molecular and Cellular Proteomics 19 (7), S. 1161 - 1178 (2020)

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43.

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Vos, S. M.; Farnung, L.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation. Nature Structural and Molecular Biology 27 (7), S. 668 - 677 (2020)

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44.

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Schulze, S.; Adams, Z.; Cerletti, M.; Castro, R. D.; Ferreira-Cerca, S.; Fufezan, C.; Giménez, M. I.; Hippler, M.; Jevtic, Z.; Knüppel, R. et al.; Legerme, G.; Lenz, C.; Marchfelder, A.; Maupin-Furlow, J.; Paggi, R. A.; Pfeiffer, F.; Poetsch, A.; Urlaub, H.; Pohlschroder, M.: The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics. Nature Communications 11, 3145 (2020)

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45.

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Parfentev, I.; Schilbach, S.; Cramer, P.; Urlaub, H.: An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples. Journal of proteomics 220, 103754 (2020)

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46.

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Specht, G.; Roetschke, H. P.; Mansurkhodzhaev, A.; Henklein, P.; Textoris-Taube, K.; Urlaub, H.; Mishto, M.; Liepe, J.: Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes. Scientific Data 7, 146 (2020)

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47.

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Singh, K.; Graf, B.; Linden, A.; Sautner, V.; Urlaub, H.; Tittmann, K.; Stark, H.; Chari, A.: Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 180 (6), S. 1130 - 1143.e20 (2020)

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48.

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Wagner, F. R; Dienemann, C.; Wang, H.; Stützer, A.; Tegunov, D.; Urlaub, H.; Cramer, P.: Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome. Nature 579 (7799), S. 448 - 451 (2020)

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49.

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Müller, M.; James, C.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Probing the environment of emerin by Enhanced ascorbate peroxidase 2 (APEX2)-mediated proximity labeling. Cells 9 (3), 605 (2020)

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50.

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Volland, C.; Schott, P.; Didié, M.; Männer, J.; Unsöld, B.; Toischer, K.; Schmidt, C.; Urlaub, H.; Nickels, K.; Knöll, R. et al.; Schmidt, A.; Guan, K.; Hasenfuß, G.; Seidler, T.: Control of p21^Cip by BRAP is critical for cardiomyocyte cell cycle progression and survival. Cardiovascular Research 116 (3), S. 592 - 604 (2020)

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51.

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Koziolek, M.; Mueller, G. A.; Dihazi, G. H.; Jung, K.; Altubar, C.; Wallbach, M.; Markovic, I.; Raddatz, D.; Jahn, O.; Karaköse, H. et al.; Lenz, C.; Urlaub, H.; Dihazi, A.; El Meziane, A.; Dihazi, H.: Urine E-cadherin: A Marker for early detection of kidney injury in diabetic patients. Journal of Clinical Medicine 9 (3), 639 (2020)

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52.

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Hamann, F.; Schmitt, A.; Favretto, F.; Hofele, R.; Neumann, P.; Xiang, S. Q.; Urlaub, H.; Zweckstetter, M.; Ficner, R.: Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proceedings of the National Academy of Sciences of the United States of America 117 (6), S. 2948 - 2956 (2020)

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53.

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Yatsenko, A. S.; Kucherenko, M. M.; Xie, Y.; Aweida, D.; Urlaub, H.; Scheibe, R. J.; Cohen, S.; Shcherbata, H. R.: Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. BMC Medicine 18 (1), 8 (2020)

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54.

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Völkel, S.; Hein, S.; Benker, N.; Pfeifer, F.; Lenz, C.; Losensky, G.: How to cope with heavy metal ions: Cellular and proteome-level stress response to divalent copper and nickel in Halobacterium salinarum R1 planktonic and biofilm cells. Frontiers in Microbiology 10, 3056 (2020)

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55.

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Godavarthy, P. S.; Kumar, R.; Herkt, S. C.; Pereira, R. S.; Hayduk, N.; Weissenberger, E. S.; Aggoune, D.; Manavski, Y.; Lucas, T.; Pan, K. T. et al.; Voutsinas, J. M.; Wu, Q.; Müller, M. C.; Saussele, S.; Oellerich, T.; Oehler, V. G.; Lausen, J.; Krause, D. S.: The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. Haematologica 105 (1), S. 136 - 147 (2020)

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56.

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Wang, H.; Dienemann, C.; Stützer, A.; Urlaub, H.; Cheung, A. C. M.; Cramer, P.: Structure of the transcription coactivator SAGA. Nature 577, S. 717 - 720 (2020)

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57.

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Keihani, S.; Klüver, V.; Mandad, S.; Bansal, V.; Rahman, R.; Fritsch, E.; Gomes, L. C.; Gärtner, A.; Kügler, S.; Urlaub, H. et al.; Wren, J. D.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.: The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43. Science Advances 5 (12), eaay2670 (2019)

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58.

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Grimm, C.; Hillen, H. S.; Bedenk, K.; Bartuli, J.; Neyer, S.; Zhang, Q.; Hüttenhofer, A.; Erlacher, M.; Dienemann, C.; Schlosser, A. et al.; Urlaub, H.; Böttcher, B.; Szalay, A. A.; Cramer, P.; Fischer, U.: Structural basis of poxvirus transcription: Vaccinia RNA polymerase complexes. Cell 179 (7), S. 1537 - 1550 (2019)

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59.

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Gowravaram, M.; Schwarz, J.; Khilji, S. K.; Urlaub, H.; Chakrabarti, S.: Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. Nature Communications 10 (1), 5054 (2019)

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60.

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Alevra, M.; Mandad, S.; Ischebeck, T.; Urlaub, H.; Rizzoli, S. O.; Fornasiero, E. F.: A mass spectrometry workflow for measuring protein turnover rates in vivo. Nature Protocols 14 (12), S. 3333 - 3365 (2019)

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61.

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Ayoubi, L. E.; Dumay-Odelot, H.; Chernev, A.; Boissier, F.; Minvielle-Sébastia, L.; Urlaub, H.; Fribourg, S.; Teichmann, M.: The hRPC62 subunit of human RNA polymerase III displays helicase activity. Nucleic Acids Research 47 (19), S. 10313 - 10326 (2019)

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62.

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James, C.; Müller, M.; Goldberg, M. W.; Lenz, C.; Urlaub, H.; Kehlenbach, R. H.: Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. The Journal of Biological Chemistry 294 (44), S. 16241 - 16254 (2019)

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63.

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Blazquez, R.; Rietkötter, E.; Wenske, B.; Wlochowitz, D.; Sparrer, D.; Vollmer, E.; Müller, G.; Seegerer, J.; Sun, X.; Dettmer, K. et al.; Barrantes-Freer, A.; Stange, L.; Utpatel, K.; Bleckmann, A.; Treiber, H.; Bohnenberger, H.; Lenz, C.; Schulz, M.; Reimelt, C.; Hackl, C.; Grade, M.; Büyüktas, D.; Siam, L.; Balkenhol, M.; Stadelmann, C.; Kube, D.; Krahn, M. P.; Proescholdt, M. A.; Riemenschneider, M. J.; Evert, M.; Oefner, P. J.; Klein, C. A.; Hanisch, U. K.; Binder, C.; Pukrop, T.: LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer. International Journal of Cancer, (in press) (2019)

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Erdmann, J.; Thöming, J. G.; Pohl, S.; Pich, A.; Lenz, C.; Häussler, S.: The core proteome of biofilm-grown clinical pseudomonas aeruginosa isolates. Cells 8 (10), 1129 (2019)

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Jevtic, Z.; Stoll, B.; Pfeiffer, F.; Sharma, K.; Urlaub, H.; Marchfelder, A.; Lenz, C.: The response of Haloferax volcanii to salt and temperature stress: A proteome study by label-free mass spectrometry. Proteomics 19 (20), 1840091 (2019)

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Bremmer, F.; Bohnenberger, H.; Küffer, S.; Oellerich, T.; Serve, H.; Urlaub, H.; Strauss, A.; Maatoug, Y.; Behnes, C. L.; Oing, C. et al.; Radzun, H. J.; Ströbel, P.; Balabanov, S.; Honecker, F.: Proteomic comparison of malignant human germ cell tumor cell lines. Disease Markers 2019, 8298524 (2019)

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Yagensky, O.; Kohansal-Nodehi, M.; Gunaseelan, S.; Rabe, T.; Zafar, S.; Zerr, I.; Haertig, W.; Urlaub, H.; Chua, J.: Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 8, e47498 (2019)

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Alsina, K. M.; Hulsurkar, M.; Brandenburg, S.; Kownatzki-Danger, D.; Lenz, C.; Urlaub, H.; Abu-Taha, I.; Kamler, M.; Chiang, D. Y.; Lahiri, S. K. et al.; Reynolds, J. O.; Quick, A. P.; Scott, L.; Word, T. A.; Gelves, M. D.; Heck, A. J. R.; Li, N.; Dobrev, D.; Lehnart, S. E.; Wehrens, X. H. T.: Loss of protein phosphatase 1 regulatory subunit PPP1R3A promotes atrial fibrillation. Circulation 140 (8), S. 681 - 693 (2019)

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Liess, A. K. L.; Kucerova, A.; Schweimer, K.; Yu, L.; Roumeliotis, T. I.; Diebold, M.; Dybkov, O.; Sotriffer, C.; Urlaub, H.; Choudhary, J. S. et al.; Mansfeld, J.; Lorenz, S.: Autoinhibition mechanism of the ubiquitin-conjugating enzyme UBE2S by autoubiquitination. Structure 27 (8), S. 1195 - 1210 (2019)

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Callegari, S.; Müller, T.; Schulz, C.; Lenz, C.; Jans, D. C.; Wissel, M.; Opazo, F.; Rizzoli, S. O.; Jakobs, S.; Urlaub, H. et al.; Rehling, P.; Deckers, M.: A MICOS-TIM22 association promotes carrier import into human mitochondria. Journal of Molecular Biology 431 (15), S. 2835 - 2851 (2019)

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Kokic, G.; Chernev, A.; Tegunov, D.; Dienemann, C.; Urlaub, H.; Cramer, P.: Structural basis of TFIIH activation for nucleotide excision repair. Nature Communications 10, 2885 (2019)

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Coy-Vergara, J.; Rivera-Monroy, J.; Urlaub, H.; Lenz, C.; Schwappach, B.: A trap mutant reveals the physiological client spectrum of TRC40. Journal of Cerll Science, (in press) (2019)

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Chachami, G.; Stankovic-Valentin, N.; Karagiota, A.; Basagianni, A.; Pleßmann, U.; Urlaub, H.; Melchior, F.; Simos, G.: Hypoxia-induced changes in SUMO conjugation affect transcriptional regulation under low oxygen. Molecular and Cellular Proteomics 18 (6), S. 1197 - 1209 (2019)

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Garofalo, R.; Wohlgemuth, I.; Pearson, M.; Lenz, C.; Urlaub, H.; Rodnina, M. V.: Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 47 (6), S. 2932 - 2945 (2019)

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Papathanasiou, P.; Erdmann, S.; Leon-Sobrino, C.; Sharma, K.; Urlaub, H.; Garrett, R. A.; Peng, X.: Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1. RNA Biology 16 (4), S. 557 - 565 (2019)

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Schroeder, M. P.; Bastian, L.; Eckert, C.; Gökbuget, N.; James, A. R.; Ortiz Tanchez, J.; Schlee, C.; Isaakidis, K.; Häupl, B.; Baum, K. et al.; Lozano, O. A. M.; Kouidri, K.; Pan, K. T.; Urlaub, H.; Schwartz, S.; Burmeister, T.; von Stackelberg, A.; Hoelzer, D.; Pfeiffer, H.; Rieger, M. A.; Göllner, S.; Oellerich, T.; Horstman, M.; Schrappe, M.; Wolf, J.; Kirschner-Schwabe, R.; Brüggemann, M.; Müller-Tidow, C.; Serve, H.; Neumann, M.; Baldus, C. D.: Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures. Scientific Reports 9 (1), 4188 (2019)

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Michels, B. E.; Mosa, M. H.; Grebbin, B. M.; Yepes, D.; Darvishi, T.; Hausmann, J.; Urlaub, H.; Zeuzem, S.; Kvasnicka, H. M.; Oellerich, T. et al.; Farin, H. F.: Human colon organoids reveal distinct physiologic and oncogenic Wnt responses. Journal of Experimental Medicine 216 (3), 704 (2019)

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Richter, F.; Dennerlein, S.; Nikolov, M.; Jans, D. C.; Naumenko, N.; Aich, A.; MacVicar, T.; Linden, A.; Jakobs, S.; Urlaub, H. et al.; Langer, T.; Rehling, P.: ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. The Journal of Cell Biology 218 (2), 598 (2019)

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Maier, L. K.; Stachler, A. E.; Brendel, J.; Stoll, B.; Fischer, S.; Haas, K.; Schwarz, T.; Alkhnbashi, O. S.; Sharma, K.; Urlaub, H. et al.; Backofen, R.; Gophna, U.; Marchfelder, A.: The nuts and bolts of the Haloferax CRISPR-Cas system I-B. RNA Biology 16 (4), S. 469 - 480 (2019)

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Masanta, W. O.; Zautner, A. E.; Lugert, R.; Bohne, W.; Gross, U.; Leha, A.; Dakna, M.; Lenz, C.: Proteome profiling by label‐free mass spectrometry reveals differentiated response of Campylobacter jejuni 81–176 to sublethal concentrations of bile acids. Proteomics 13 (3), 1800083 (2019)

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Mishto, M.; Mansurkhodzhaev, A.; Ying, G.; Bitra, A.; Cordfunke, R. A.; Henze, S.; Paul, D.; Sidney, J.; Urlaub, H.; Neefjes, J. et al.; Sette, A.; Zajonc, D. M.; Liepe, J.: An in silico-in vitro pipeline identifying an HLA-A^*02:01⁺ KRAS G12V⁺ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 10, 2572 (2019)

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Özcan, A.; Pausch, P.; Linden, A.; Wulf, A.; Schühle, K.; Heider, J.; Urlaub, H.; Heimerl, T.; Bange, G.; Randau, L.: Type IV CRISPR RNA processing and effector complex formation in Aromatoleum aromaticum. Nature Microbiology 4 (1), S. 89 - 96 (2019)

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Ramani, A.; Mariappan, A.; Gottardo, M.; Mandad, S.; Urlaub, H.; Avidor-Reiss, T.; Riparbelli, M.; Giuliano, C.; Debec, A.; Feederle, R. et al.; Gopalakrishnan, J.: Plk1/Polo phosphorylates Sas-4 at the onset of mitosis for an efficient recruitment of pericentriolar material to centrosomes. Cell Reports 25 (13), S. 3618 - 3630 (2018)

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Brüning, L.; Hackert, P.; Martin, R.; Gallesio, J. D.; Aquino, G. R. R.; Urlaub, H.; Sloan, K. E.; Bohnsack, M. T.: RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes. Nature Communications 9, 5383 (2018)

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Braun, J.; Fischer, S.; Xu, Z. Z.; Dalia, S.; Ghoneim, D. H.; Gimbel, A. T.; Plessmann, U.; Urlaub, H.; Mathews, D. H.; Weigand, J. E.: Identification of new high affinity targets for Roquin based on structural conservation. Nucleic Acids Research 46 (22), S. 12109 - 12125 (2018)

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Mandad, S.; Rahman, R. U.; Centeno, T. P.; Vidal, R. O.; Wildhagen, H.; Rammner, B.; Keihani, S.; Opazo, F.; Urban, I.; Ischebeck, T. et al.; Kirli, K.; Benito, E.; Fischer, A.; Yousefi, R. Y.; Dennerlein, S.; Rehling, P.; Feussner, I.; Urlaub, H.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.: The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Scientific Reports 8, 16913 (2018)

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Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C. T.; Perez-Lara, A.; Chakraborty, P.; Hofele, R. V.; Baker, J. D.; Blair, L. J.; Biernat, J. et al.; Urlaub, H.; Mandelkow, E.; Dickey, C. A.; Zweckstetter, M.: Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 9, 4532 (2018)

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Lavdovskaia, E.; Kolander, E.; Steube, E.; Mai, M. M.; Urlaub, H.; Richter-Dennerlein, R.: The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis. Nucleic Acids Research 46 (16), S. 8471 - 8482 (2018)

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Blaschke, M.; Koepp, R.; Lenz, C.; Kruppa, J.; Jung, K.; Siggelkow, H.: Crohn's disease patient serum changes protein expression in a human mesenchymal stem cell model in a linear relationship to patients' disease stage and to bone mineral density. Journal of Clinical and Translational Endocrinology 13, S. 26 - 38 (2018)

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Vos, S. M.; Farnung, L.; Böhning, M.; Wigge, C.; Linden, A.; Urlaub, H.; Cramer, P.: Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature 560 (7720), S. 607 - 612 (2018)

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Vos, S. M.; Farnung, L.; Urlaub, H.; Cramer, P.: Structure of paused transcription complex Pol II–DSIF–NELF. Nature 560 (7720), S. 601 - 606 (2018)

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Mühlhausen, S.; Schmitt, H. D.; Pan, K. T.; Plessmann, U.; Urlaub, H.; Hurst, L. D.; Kollmar, M.: Endogenous stochastic decoding of the CUG codon by competing Ser- and Leu-tRNAs in Ascoidea asiatica. Current Biology 28 (13), S. 2046 - 2057 (2018)

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Aksu, M.; Pleiner, T.; Karaca, S.; Kappert, C.; Dehne, H. J.; Seibel, K.; Urlaub, H.; Bohnsack, M. T.; Görlich, D.: Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 217 (7), S. 2329 - 2340 (2018)

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Cyganek, L.; Tiburcy, M.; Sekeres, K.; Gerstenberg, K.; Bohnenberger, H.; Lenz, C.; Henze, S.; Stauske, M.; Salinas, G.; Zimmermann, W. H. et al.; Hasenfuss, G.; Guan, K.: Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes. JCI Insight 3 (12), e99941 (2018)

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Johannsson, S.; Neumann, P.; Wulf, A.; Welp, L. M.; Gerber, H. D.; Krull, M.; Diederichsen, U.; Urlaub, H.; Ficner, R.: Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. Scientific Reports 8, 8880 (2018)

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