Publikationen

Kirli, K.; Karaca, S.; Dehne, H. J.; Samwer, M.; Pan, K. T.; Lenz, C.; Urlaub, H.; Görlich, D.: A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. eLife 4, e11466 (2015)

Absmeier, E.; Wollenhaupt, J.; Mozaffari-Jovin, S.; Becke, C.; Lee, C. T.; Preussner, M.; Heyd, F.; Urlaub, H.; Lührmann, R.; Santos, K. F. et al.; Wahl, M. C.: The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes and Development 29 (24), S. 2576 - 2587 (2015)

Pleiner, T.; Bates, M.; Trakhanov, S.; Lee, C. T.; Schliep, J. E.; Chug, H.; Böhning, M.; Stark, H.; Urlaub, H.; Görlich, D.: Nanobodies: Site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. eLife 4, e11349 (2015)

Crisci, C.; Raleff, F.; Bagdul, I.; Raabe, M.; Urlaub, H.; Rain, J. C.; Krämer, A.: Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins. Nucleic Acids Research 43 (21), S. 10456 - 10473 (2015)

Zaman, U.; Richter, F. M.; Hofele, R. V.; Kramer, K.; Sachsenberg, T.; Kohlbacher, O.; Lenz, C.; Urlaub, H.: Dithiothreitol (DTT) acts as a specific, UV-inducible cross-linker in elucidation of protein-RNA interactions. Molecular and Cellular Proteomics 14 (12), S. 3196 - 3210 (2015)

Sharma, K.; Hrle, A.; Kramer, K.; Sachsenberg, T.; Staals, R. H. J.; Randau, L.; Marchfelder, A.; van der Oost, J.; Kohlbacher, O.; Conti, E. et al.; Urlaub, H.: Analysis of protein–RNA interactions in CRISPR proteins and effector complexes by UV-induced cross-linking and mass spectrometry. Methods 89, S. 138 - 148 (2015)

Port, S. A.; Monecke, T.; Dickmanns, A.; Spillner, C.; Hofele, R.; Urlaub, H.; Ficner, R.; Kehlenbach, H.: Structural and functional characterization of CRM1-Nup214 interactions reveals multiple FG-binding sites involved in nuclear export. Cell Reports 13 (4), S. 690 - 702 (2015)

Sakin, V.; Richter, S. M.; Hsiao, H. H.; Urlaub, H.; Melchior, F.: Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 ligase complex. Journal of Biological Chemistry 290 (39), S. 23598 - 23602 (2015)

Boesler, C.; Rigo, N.; Agafonov, D. E.; Kastner, B.; Urlaub, H.; Will, C. L.; Lührmann, R.: Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5‘ splice site. RNA 21 (11), S. 1993 - 2005 (2015)

Diaz, S. A.; Malonoski, A. P.; Susumu, K.; Hofele, R. V.; Oh, E.; Medintz, I. L.: Probing the kinetics of quantum dot-based proteolytic sensors. Analytical and Bioanalytical Chemistry 407 (24), S. 7307 - 7318 (2015)

Salat , D.; Winkler, A.; Urlaub, H.; Gessler, M.: Hey bHLH proteins interact with a FBXO45 containing SCF ubiquitin ligase complex and induce its translocation into the nucleus. PLOS One 10 (6), e0130288 (2015)

Kuvardina, O. N.; Herglotz, J.; Kolodziej, S.; Kohrs, N.; Herkt, S.; Wojcik, B.; Oellerich, T.; Corso, J.; Behrens, K.; Kumar, A. et al.; Hussong, H.; Urlaub, H.; Koch, J.; Serve, H.; Bonig, H.; Stocking, C.; Rieger, M. A.; Lausen, J.: RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation. Blood 125 (23), S. 3570 - 3579 (2015)

Kadavath, H.; Hofele, R. V.; Biernat, J.; Kumar, S.; Tepper, K.; Urlaub, H.; Mandelkow, E.; Zweckstetter, M.: Tau stabilizes microtubules by binding at the interface between tubulin heterodimers. Proceedings of the National Academy of Sciences of the United States of America 112 (24), S. 7501 - 7506 (2015)

Cass, S. D. B.; Haas, K. A.; Stoll, B.; Alkhnbashi, O. S.; Sharma, K.; Urlaub, H.; Backofen, R.; Marchfelder, A.; Bolt, E. L.: The role of Cas8 in type I CRISPR interference. Bioscience Reports 35 (3), e00197 (2015)

Kost, N.; Kaiser, S.; Ostwal, Y.; Riedel, D.; Stützer, A.; Nikolov, M.; Rathke, C.; Renkawitz-Pohl, R.; Fischle, W.: Multimerization of Drosophila sperm protein Mst77F causes a unique condensed chromatin structure. Nucleic Acids Research 43 (6), S. 3033 - 3045 (2015)

Oellerich, T.; Mohr, S.; Corso, J.; Beck, J.; Döbele, C.; Braun, H.; Cremer, A.; Münch, S.; Wicht, J.; Oellerich, M. F. et al.; Bug, G.; Bohnenberger, H.; Perske, C.; Schütz, E.; Urlaub, H.; Serve, H.: FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation. Blood 125 (12), S. 1936 - 1947 (2015)

Jorrin-Novo, J. V.; Pascual, J.; Sanchez-Lucas, R.; Romero-Rodriguez, M. C.; Rodriguez-Ortega, M. J.; Lenz, C.; Valledor, L.: Fourteen years of plant proteomics reflected in Proteomics: Moving from model species and 2DE-based approaches to orphan species and gel-free platforms. Proteomics 15 (5-6), S. 1089 - 1112 (2015)

Lin, T. Y.; Voronovsky, A.; Raabe, M.; Urlaub, H.; Sander, B.; Golas, M. M.: Dual tagging as an approach to isolate endogenous chromatin remodeling complexes from Saccharomyces cerevisiae. Biochimica et Biophysica Acta - Proteins and Proteomics 1854 (3), S. 198 - 208 (2015)

Timm, T.; Lenz, C.; Merkel, D.; Sadiffo, C.; Grabitzki, J.; Klein, J.; Lochnit, G.: Detection and site localization of phosphorylcholine-modified peptides by NanoLC-ESI-MS/MS using precursor ion scanning and multiple reaction monitoring experiments. Journal of the American Society of Mass Spectrometry 26 (3), S. 460 - 471 (2015)

Wohlgemuth, I.; Lenz, C.; Urlaub, H.: Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 15 (5-6), S. 862 - 879 (2015)

Bohnenberger, H.; Ströbel, P.; Mohr, S.; Corso, J.; Berg, T.; Urlaub, H.; Lenz, C.; Serve, H.; Oellerich, T.: Quantitative mass spectrometric profiling of cancer-cell proteomes derived from liquid and solid tumors. Journal of Visualized Experiments 96, e52435 (2015)

De, I.; Bessonov, S.; Hofele, R.; Dos Santos, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: The RNA helicase ​Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology 22 (2), S. 138 - 144 (2015)

Lugassy, J.; Corso, J.; Beach, D.; Petrik, T.; Oellerich, T.; Urlaub, H.; Yablonski, D.: Modulation of TCR responsiveness by the Grb2-family adaptor, Gads. Cellular Signalling 27 (1), S. 125 - 134 (2015)

Qamar, S.; Kramer, K.; Urlaub, H.: Studying RNA-protein interactions of pre-mRNA complexes by mass spectrometry. In: Structures of large RNA molecules and their complexes, S. 417 - 463 (Hg. Woodson, S. A.; Allain, F. H. T.). Elsevier, Amsterdam (2015)