Publications

Callegari, S.; Richter, F.; Chojnacka, K.; Jans, D. C.; Lorenzi, I.; Pacheu-Grau, D.; Jakobs, S.; Lenz, C.; Urlaub, H.; Dudek, J. et al.; Chacinska, A.; Rehling, P.: TIM29 is a subunit of the human carrier translocase required for protein transport. FEBS Letters 590 (23), pp. 4147 - 4158 (2016)

Strenzke, N.; Chakrabarti, R.; Al-Moyed, H.; Müller, A.; Hoch, G.; Pangrsic, T.; Yamanbaeva, G.; Lenz, C.; Pan, K. T.; Auge, E. et al.; Geiss-Friedlander, R.; Urlaub, H.; Brose, N.; Wichmann, C.; Reisinger, E.: Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants. EMBO Journal 35 (23), pp. 2519 - 2535 (2016)

Zhang, J. N.; Michel, U.; Lenz, C.; Friedel, C. C.; Köster, S.; d'Hedouville, Z.; Tönges, L.; Urlaub, H.; Bähr, M.; Lingor, P. et al.; Koch, J. C.: Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration. Scientific Reports 6, 37050 (2016)

Manno, B.; Oellerich, T.; Schnyder, T.; Corso, J.; Lösing, M.; Neumann, K.; Urlaub, H.; Batista, F. D.; Engelke, M.; Wienands, J.: The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner. European Journal of Immunology 46 (11), pp. 2520 - 2530 (2016)

Cretu, C.; Schmitzova, J.; Ponce-Salvatierra, A.; Dybkov, O.; De Laurentiis, E.; Sharma, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: Molecular architecture of SF3b and structural consequences of its cancer-related mutations. Molecular Cell 64 (2), pp. 307 - 319 (2016)

Martin, S.; Bellora, N.; González-Vallinas, J.; Irimia, M.; Chebli, K.; DeToledo, M.; Raabe, M.; Eyras, E.; Urlaub, H.; Blencowe, B. J. et al.; Tazi, J.: Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum. Journal of Neurochemistry 139 (3), pp. 349 - 368 (2016)

Hsu, M. F.; Pan, K. T.; Chang, F. Y.; Khoo, K. H.; Urlaub, H.; Cheng, C. F.; Chang, G. D.; Haj, F. G.; Meng, T. C.: S-nitrosylation of endogenous protein tyrosine phosphatases in endothelial insulin signaling. Free Radical Biology and Medicine 99, pp. 199 - 213 (2016)

Rauhut, R.; Fabrizio, P.; Dybkov, O.; Hartmuth, K.; Pena, V.; Chari, A.; Kumar, V.; Lee, C. T.; Urlaub, H.; Kastner, B. et al.; Stark, H.; Lührmann, R.: Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 353 (6306), pp. 1399 - 1405 (2016)

Justa-Schuch, D.; Silvia-Garcia, M.; Pilla, E.; Engelke, M.; Kilisch, M.; Lenz, C.; Möller, U.; Nakamura, F.; Urlaub, H.; Geiss-Friedlander, R.: DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. eLife 5, e16370 (2016)

Veit, J.; Sachsenberg, T.; Chernev, A.; Aichler, F.; Urlaub, H.; Kohlbacher, O.: LFQProfiler and RNPxl: Open-source tools for label-free quantification and protein-RNA cross-linking integrated into Proteome Discoverer. Journal of Proteome Research 15 (9), pp. 3441 - 3448 (2016)

Agafonov, D. E.; van Santen, M.; Kastner, B.; Dube, P.; Will, C. L.; Urlaub, H.; Lührmann, R.: ATPγS stalls splicing after B complex formation but prior to spliceosome activation. RNA 22 (9), pp. 1329 - 1337 (2016)

Narayanan, P.; Sondermann, J.; Rouwette, T.; Karaca, S.; Urlaub, H.; Mitkovski, M.; Gomez-Varela, D.; Schmidt, M.: Native Piezo2 interactomics identifies pericentrin as a novel regulator of Piezo2 in somatosensory neurons. Journal of Proteome Research 15 (8), pp. 2676 - 2687 (2016)

Helmke, C.; Raab, M.; Rödel, F.; Matthess, Y.; Oellerich, T.; Mandal, R.; Sanhaji, M.; Urlaub, H.; Rödel, C.; Becker, S. et al.; Strebhardt, K.: Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8. Cell Research 26 (8), pp. 914 - 934 (2016)

Lazzaretti, D.; Veith, K.; Kramer, K.; Basquin, C.; Urlaub, H.; Iron, U.; Bono, F.: The bicoid mRNA localization factor Exuperantia is an RNA-binding pseudonuclease. Nature Structural and Molecular Biology 23 (8), pp. 705 - 713 (2016)

Gleditzsch, D.; Müller-Esparza, H.; Pausch, P.; Sharma, K.; Dwarakanath, S.; Urlaub, H.; Bange, G.; Randau, L.: Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system. Nucleic Acids Research 44 (12), pp. 5872 - 5882 (2016)

Seehusen, F.; Kiel, K.; Jottini, S.; Wohlsein, P.; Habierski, H.; Seibel, K.; Vogel, T.; Urlaub, H.; Kollmar, M.; Baumgärtner, W. et al.; Teichmann, U.: Axonopathy in the central nervous system is the hallmark of mice with a novel intragenic null mutation of dystonin. Genetics 204 (1), pp. 191 - 203 (2016)

Boesler, C.; Rigo, N.; Anokhina, M. M.; Tauchert, M. J.; Agafonov, D. E.; Kastner, B.; Urlaub, H.; Ficner, R.; Will, C. L.; Lührmann, R.: A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity. Nature Communications 7, 11997 (2016)

Mühlhausen, S.; Findeisen, P.; Plessmann, U.; Urlaub, H.; Kollmar, M.: A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes. Genome Research 26 (7), pp. 945 - 955 (2016)

Kühn, J.; Wong, L. E.; Pirkuliyeva, S.; Schulz, K.; Schwiegk, C.; Fünfgeld, K.; Keppler, S.; Batista, F. D.; Urlaub, H.; Habeck, M. et al.; Becker, S.; Griesinger, C.; Wienands, J.: The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation. Science Signaling 9 (434), ra66 (2016)

Butkevich, E.; Hartig, W.; Nikolov, M.; Erck, C.; Grosche, J.; Urlaub, H.; Schmidt, C. F.; Klopfenstein, D. R.; Chua, J. J. E.: Phosphorylation of FEZ1 by microtubule affinity regulating kinases regulates its function in presynaptic protein trafficking. Scientific Reports 6, 26965 (2016)

Bareth, B.; Nikolov, M.; Lorenzi, I.; Hildenbeutel, M.; Mick, D. U.; Helbig, C.; Urlaub, H.; Ott, M.; Rehling, P.; Dennerlein, S.: Oms1 associates with cytochrome c oxidase assembly intermediates to stabilize newly synthesized Cox1. Molecular Biology of the Cell 27 (10), pp. 1570 - 1580 (2016)

Corso, J.; Pan, K. T.; Walter, R.; Doebele, C.; Mohr, S.; Bohnenberger, H.; Ströbel, P.; Lenz, C.; Slabicki, M.; Hüllein, J. et al.; Comoglio, F.; Rieger, M. A.; Zenz, T.; Wienands, J.; Engelke, M.; Serve, H.; Urlaub, H.; Oellerich, T.: Elucidation of tonic and activated B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survival. Proceedings of the National Academy of Sciences of the United States of America 113 (20), pp. 5688 - 5693 (2016)

Fourmann, J. B.; Dybkov, O.; Agafonov, D. E.; Tauchert, M. J.; Urlaub, H.; Ficner, R.; Fabrizio, P.; Lührmann, R.: The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction. eLife 5, e15564 (2016)

Kohansalnodehi, M.; Chua, J. J.; Urlaub, H.; Jahn, R.; Czernik, D.: Analysis of protein phosphorylation in nerve terminal reveals extensive changes in active zone proteins upon exocytosis. eLife 5, e14530 (2016)

Hiragami-Hamada, K.; Sörös, S.; Nikolov, M.; Wilkins, B.; Kreuz, S.; Chen, C.; De La Rosa-Velazquez, I. A.; Zenn, H. M.; Kost, N.; Pohl, W. et al.; Chernev, A.; Schwarzer, D.; Jenuwein, T.; Lorincz, M.; Zimmermann, B.; Walla, P. J.; Neumann, H.; Baubec, T.; Urlaub, H.; Fischle, W.: Dynamic and flexible H3K9me3 bridging via HP1beta dimerization establishes a plastic state of condensed chromatin. Nature Communications 7, 11310 (2016)

Shao, Y. M.; Richter , H.; Sun, S.; Sharma, K.; Urlaub, H.; Randau, L.: A non-stem-loop CRISPR RNA is processed by dual binding Cas6. Structure 24 (4), pp. 547 - 554 (2016)

Khan, N.; Lenz, C.; Binder, L.; Pantakani, D. V. K.; Asif, A. R.: Active and repressive chromatin-associated proteome after MPA treatment and the role of midkine in epithelial monolayer permeability. International Journal of Molecular Sciences 17 (4), 597 (2016)

Agafonov, D. E.; Kastner, B.; Dybkov, O.; Hofele, R. V.; Liu, W.; Urlaub, H.; Lührmann, R.; Stark, H.: Molecular architecture of the human U4/U6.U5 tri-snRNP. Science 351 (6280), pp. 1416 - 1420 (2016)

Heininger, A. U.; Hackert, P.; Andreou, A. Z.; Boon, K. L.; Memet, I.; Prior, M.; Clancy, A.; Schmidt, B.; Urlaub, H.; Schleiff, E. et al.; Sloan, K. E.; Deckers, M.; Lührmann, R.; Enderlein, J.; Klostermeier, D.; Rehling, P.; Bohnsack, M. T.: Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways. RNA Biology 13 (3), pp. 320 - 330 (2016)

Cicek, I. Ö.; Karaca, S.; Brankatschk, M.; Eaton, S.; Urlaub, H.; Shcherbata, H. R.: Hedgehog signaling strength is orchestrated by the mir-310 cluster of microRNAs in response to diet. Genetics 202 (3), pp. 1167 - 1183 (2016)

Koch, H.; Raabe, M.; Urlaub, H.; Bindereif, A.; Preußer, C.: The polyadenylation complex of Trypanosoma brucei: Characterization of the functional poly(A) polymerase. RNA Biology 13 (2), pp. 221 - 231 (2016)

Lenz, C.; Dihazi, H.: Introduction to proteomics technologies. In: Statistical analysis in proteomics, pp. 3 - 27 (Ed. Jung, K.). Springer; Humana Pr., New York, N.Y. (2016)