Publications

102.

Journal Article

Bornemann, T.; Holtkamp, W.; Wintermeyer, W.: Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 5, 4180 (2014)

MPG.PuRe

103.

Journal Article

Holtkamp, W.; da Cunha, C. E. L.; Peske, F.; Konevega, A. L.; Wintermeyer, W.; Rodnina, M. V.: GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 33 (9), pp. 1073 - 1085 (2014)

MPG.PuRe

104.

Journal Article

Peske, F.; Kuhlenkötter, S.; Rodnina, M. V.; Wintermeyer, W.: Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 42 (3), pp. 1812 - 1820 (2014)

MPG.PuRe

105.

Journal Article

Bock, L. V.; Blau, C.; Schröder, G. F.; Davydov, I. I.; Fischer, N.; Stark, H.; Rodnina, M. V.; Vaiana, A. C.; Grubmüller, H.: Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 20 (12), pp. 1390 - 1396 (2013)

MPG.PuRe

106.

Journal Article

Dörfel, L. K.; Rodnina, M. V.: Elongation factor P: Function and effects on bacterial fitness. Biopolymers 99 (11), pp. 837 - 845 (2013)

MPG.PuRe

107.

Journal Article

Mittelstät, J.; Konevega, A. L.; Rodnina, M. V.: A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. Journal of the American Chemical Society 135 (45), pp. 17031 - 17038 (2013)

MPG.PuRe

108.

Journal Article

Rodnina, M. V.: The ribosome as a versatile catalyst: Reactions at the peptidyl transferase center. Current Opinion in Structural Biology 23 (4), pp. 595 - 602 (2013)

MPG.PuRe

109.

Journal Article

Rezgui, V. A. N.; Kshitiz, T.; Namit, R.; Konevega, A. L.; Mittelstät, J.; Rodnina, M. V.; Peter, M.; Pedrioli, P. G. A.: tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding. Proceedings of the National Academy of Sciences of the United States of America 110 (30), pp. 12289 - 12294 (2013)

MPG.PuRe

110.

Journal Article

Rodnina, M. V.: Translocation in action. Science 340 (6140), pp. 1534 - 1535 (2013)

MPG.PuRe

111.

Journal Article

da Cunha, C. E. L.; Belardinelli, R.; Peske, F.; Holtkamp, W.; Wintermeyer, W.; Rodnina, M. V.: Dual use of GTP hydrolysis by elongation factor G on the ribosome. Translation 1 (1), e24315 (2013)

MPG.PuRe

112.

Journal Article

Davydov, I.; Wohlgemuth, I.; Artamonova, I. I.; Urlaub, H.; Tonevitzky, A. G.; Rodnina, M. V.: Evolution of the protein stoichiometry in the L12 stalk of bacterial and organellar ribosomes. Nature Communications 4, 1387 (2013)

MPG.PuRe

113.

Journal Article

Doerfel, L. K.; Wohlgemuth, I.; Kothe, C.; Peske, F.; Urlaub, H.; Rodnina, M. V.: EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science 339 (6115), pp. 85 - 88 (2013)

MPG.PuRe

114.

Journal Article

Holtkamp, W.; Lee, S.; Bornemann, T.; Senyushkina, T.; Rodnina, M. V.; Wintermeyer, W.: Dynamic switch of the signal recognition particle from scanning to targeting. Nature Structural and Molecular Biology 19 (12), pp. 1332 - 1337 (2012)

MPG.PuRe

115.

Journal Article

Khoshnevis, S.; Hauer, F.; Milon, P.; Stark, H.; Ficner, R.: Novel insights into the architecture and protein interaction network of yeast eIF3. RNA 18 (12), pp. 2306 - 2319 (2012)

MPG.PuRe

116.

Journal Article

Paleskava, A.; Konevega, A. L.; Rodnina, M. V.: Thermodynamics of the GTP-GDP operated conformational switch of selenocysteine-specific translation factor SelB. Journal of Biological Chemistry 287 (33), pp. 27906 - 27912 (2012)

MPG.PuRe

117.

Journal Article

Milon, P.; Rodnina, M. V.: Kinetic control of translation initiation in bacteria. Critical Reviews in Biochemistry and Molecular Biology 47 (4), pp. 334 - 348 (2012)

MPG.PuRe

118.

Journal Article

Burakovsky, D. E.; Prokhorova, I. V.; Sergiev, P. V.; Milon, P.; Sergeeva, O. V.; Bogdanov, A. A.; Rodnina, M. V.; Dontsova, O. A.: Impact of methylations of m2G966/m5C967 in 16S rRNA on bacterial fitness and translation initiation. Nucleic Acids Research 40 (16), pp. 7885 - 7895 (2012)

MPG.PuRe

119.

Journal Article

Cox, G.; Thompson, G. S.; Jenkins, H. T.; Peske, F.; Savelsbergh, A.; Rodnina, M. V.; Wintermeyer, W.; Homans, S. W.; Edwards, T. A.; O'Neill, A. J.: Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid. Proceedings of the National Academy of Sciences of the United States of America 109 (6), pp. 2102 - 2107 (2012)

MPG.PuRe

120.

Journal Article

Milon, P.; Maracci, C.; Filonava, L.; Gualerzi, C. O.; Rodnina, M. V.: Real-time assembly landscape of bacterial 30S translation initiation complex. Nature Structural and Molecular Biology 19 (6), pp. 609 - 615 (2012)

MPG.PuRe

121.

Journal Article

Tzivelekidis, T.; Jank, T.; Pohl, C.; Schlosser, A.; Rospert, S.; Knudsen, C. R.; Rodnina, M. V.; Belyi, Y.; Aktories, K.: Aminoacyl-tRNA-charged eukaryotic elongation factor 1A is the bona fide substrate for legionella pneumophila effector glucosyltransferases. PLoS One 6 (12), e29525 (2011)

MPG.PuRe

122.

Journal Article

Wohlgemuth, I.; Pohl, C.; Mittelstät, J.; Konevega, A. L.; Rodnina, M. V.: Evolutionary optimization of speed and accuracy of decoding on the ribosome. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 366 (1580), pp. 2979 - 2986 (2011)

MPG.PuRe

123.

Journal Article

Burakovsky, D. E.; Sergiev, P. V.; Steblyanko, M. A.; Konevega, A. L.; Bogdanov, A. A.; Dontsova, O. A.: The structure of helix 89 of 23S rRNA is important for peptidyl transferase function of Escherichia coli ribosome. FEBS Letters 585 (19), pp. 3073 - 3078 (2011)

MPG.PuRe

124.

Journal Article

Kuhlenkötter, S.; Wintermeyer, W.; Rodnina, M. V.: Different substrate-dependent transition states in the active site of the ribosome. Nature 476, pp. 351 - 354 (2011)

MPG.PuRe

125.

Journal Article

Julian, P.; Milon, P.; Agirrezabala, X.; Lasso, G.; Gil, D.; Rodnina, M. V.; Valle, M.: The cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli. PLoS Biology 9 (7), e1001095 (2011)

MPG.PuRe

126.

Journal Article

Mittelstät, J.; Konevega, A. L.; Rodnina, M. V.: Distortion of tRNA upon near-cognate codon recognition on the ribosome. Journal of Biological Chemistry 286 (10), pp. 8158 - 8164 (2011)

MPG.PuRe

127.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: The ribosome as a molecular machine: The mechanism of tRNA–mRNA movement in translocation. Biochemical Society Transactions 39, pp. 658 - 662 (2011)

MPG.PuRe

128.

Journal Article

Wintermeyer, W.; Rodnina, M. V.: Genauigkeit und Geschwindigkeit der Proteinsynthese. Biospektrum 17 (4), pp. 389 - 392 (2011)

MPG.PuRe

129.

Journal Article

Wohlgemuth, I.; Pohl, W.; Rodnina, M. V.: Optimization of speed and accuracy of decoding in translation. The EMBO Journal 29 (21), pp. 3701 - 3709 (2010)

MPG.PuRe

130.

Journal Article

Milon, P.; Carotti, M.; Konevega, A. L.; Wintermeyer, W.; Rodnina, M. V.; Gualerzi, C. O.: The ribosome-bound initiation factor 2 recruits initiator tRNA to the 30S initiation complex. EMBO Reports 11 (4), pp. 312 - 316 (2010)

MPG.PuRe

131.

Journal Article

Rodnina, M. V.: Protein synthesis meets ABC ATPases: new roles for Rli1/ABCE1. EMBO Reports 11 (3), pp. 143 - 144 (2010)

MPG.PuRe

132.

Journal Article

Paleskava, A.; Konevega, A. L.; Rodnina, M. V.: Thermodynamic and kinetic framework of selenocysteyl-tRNA(Sec) recognition by elongation factor SelB. The Journal of Biological Chemistry 285 (5), pp. 3014 - 3020 (2010)

MPG.PuRe

133.

Journal Article

Burakovsky, D. E.; Sergiev, P. V.; Steblyanko, M. A.; Kubarenko, A. V.; Konevega, A. L.; Bogdanov, A. A.; Rodnina, M. V.; Dontsova, O. A.: Mutations at the accommodation gate of the ribosome impair RF2-dependent translation termination. RNA 16 (9), pp. 1848 - 1853 (2010)

MPG.PuRe

134.

Journal Article

Byrne, R. T.; Konevega, A. L.; Rodnina, M. V.; Antson, A. A.: The crystal structure of unmodified tRNA^Phe from Escherichia coli. Nucleic Acids Research 38 (12), pp. 4154 - 4162 (2010)

MPG.PuRe

135.

Journal Article

Fischer, N.; Konevega, A. L.; Wintermeyer, W.; Rodnina, M. V.; Stark, H.: Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy. Nature 466 (7304), pp. 329 - 333 (2010)

MPG.PuRe

136.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: The ribosome goes Nobel. Trends in Biochemical Sciences 35 (1), pp. 1 - 5 (2010)

MPG.PuRe

137.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: Recent mechanistic insight into eukaryotic ribosomes. Current Opinion in Cell Biology 21 (3), pp. 435 - 443 (2009)

MPG.PuRe

138.

Journal Article

Savelsbergh, A.; Rodnina, M. V.; Wintermeyer, W.: Distinct functions of elongation factor G in ribosome recycling and translocation. RNA 15 (5), pp. 772 - 780 (2009)

MPG.PuRe

139.

Journal Article

Rodnina, M. V.: Long-range signalling in activation of the translational GTPase EF-Tu. EMBO Journal 28 (6), pp. 619 - 620 (2009)

MPG.PuRe

140.

Journal Article

Rodnina, M. V.: Visualizing the protein synthesis machinery: New focus on the translational GTPase elongation factor Tu. Proceedings of the National Academy of Sciences of the United States of America 106 (4), pp. 969 - 970 (2009)

MPG.PuRe

141.

Journal Article

Buskiewicz, I. A.; Jöckel, J.; Rodnina, M. V.; Wintermeyer, W.: Conformation of the signal recognition particle in ribosomal targeting complexes. RNA 15 (1), pp. 44 - 54 (2009)

MPG.PuRe

142.

Journal Article

Wohlgemuth, I.; Brenne, S.; Beringer, M.; Rodnina, M. V.: Modulation of the rate of peptidyl transfer on the ribosome by the nature of substrates. Journal of Biological Chemistry 283 (47), pp. 32229 - 32235 (2008)

MPG.PuRe

143.

Journal Article

Bruell, C. M.; Eichholz, C.; Kubarenko, A.; Post, V.; Katunin, V. I.; Hobbie, S. N.; Rodnina, M. V.; Boettger, E. C.: Conservation of bacterial protein synthesis machinery: initiation and elongation in mycobacterium smegmatis. Biochemistry 47 (34), pp. 8828 - 8839 (2008)

MPG.PuRe

144.

Journal Article

Lancaster, L. E.; Savelsbergh, A.; Kleanthous, C.; Wintermeyer, W.; Rodnina, M. V.: Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes. Molecular Microbiology 69 (2), pp. 390 - 401 (2008)

MPG.PuRe

145.

Journal Article

Milon, P.; Konevega, A. L.; Gualerzi, C. O.; Rodnina, M. V.: Kinetic checkpoint at a late step in translation initiation. Molecular Cell 30 (6), pp. 712 - 720 (2008)

MPG.PuRe

146.

Journal Article

Kingery, D. A.; Pfund, E.; Voorhees, R. M.; Okuda, K.; Wohlgemuth, I.; Kitchen, D. E.; Rodnina, M. V.; Strobel, S. A.: An uncharged amine in the transition state of the ribosornal peptidyl transfer reaction. Chemistry and Biology 15 (5), pp. 493 - 500 (2008)

MPG.PuRe

147.

Journal Article

Bornemann, T.; Joeckel, J.; Rodnina, M. V.; Wintermeyer, W.: Signal sequence–independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel. Nature Structural and Molecular Biology 15, pp. 494 - 499 (2008)

MPG.PuRe

148.

Journal Article

Julian, P.; Konevega, A. L.; Scheres, S. H. W.; Lazaro, M.; Gil, D.; Wintermeyer, W.; Rodnina, M. V.; Valle, M.: Structure of ratcheted ribosomes with tRNAs in hybrid states. Proceedings of the National Academy of Sciences of the United States of America 105 (44), pp. 16924 - 16927 (2008)

MPG.PuRe