Publications

52.

Journal Article

Belardinelli, R.; Rodnina, M. V.: Effect of fusidic acid on the kinetics of molecular motions during EF-G-induced translocation on the ribosome. Scientific Reports 7, 10536 (2017)

MPG.PuRe

53.

Journal Article

Florin, T.; Maracci, C.; Graf, M.; Karki, P.; Klepacki, D.; Berninghausen, O.; Beckmann, R.; Vazquez-Laslop, N.; Wilson, D. N.; Rodnina, M. V. et al.; Mankin, A. S.: An antimicrobial peptide that inhibits translation by trapping release factor trap. Nature Structural and Molecular Biology 24 (9), pp. 752 - 757 (2017)

MPG.PuRe

54.

Journal Article

Agirrezabala, X.; Samatova, E. N.; Klimova, M.; Zamora, M.; Gil-Carton, D.; Rodnina, M. V.; Valle, M.: Ribosome rearrangements at the onset of translational bypassing. Science Advances 3 (6), e1700147 (2017)

MPG.PuRe

55.

Journal Article

Caliskan, N.; Wohlgemuth, I.; Korniy, N.; Pearson, M.; Peske, F.; Rodnina, M. V.: Conditional switch between frameshifting regimes upon translation of dnaX mRNA. Molecular Cell 66 (4), pp. 558 - 567 (2017)

MPG.PuRe

56.

Journal Article

Ranjan, A.; Mercier, E.; Bhatt, A.; Wintermeyer, W.: Signal recognition particle prevents N-terminal processing of bacterial membrane proteins. Nature Communications 8, 15562 (2017)

MPG.PuRe

57.

Journal Article

Ranjan, N.; Rodnina, M. V.: Thio-modification of tRNA at the wobble position as regulator of the kinetics of decoding and translocation on the ribosome. Journal of the American Chemical Society 139 (16), pp. 5857 - 5864 (2017)

MPG.PuRe

58.

Journal Article

Rodnina, M. V.; Fischer, N.; Maracci, C.; Stark, H.: Ribosome dynamics during decoding. Philosophical Transactions of the Royal Society B 372 (1716), 20160182 (2017)

MPG.PuRe

59.

Journal Article

Thommen, M.; Holtkamp, W.; Rodnina, M. V.: Co-translational protein folding: Progress and methods. Current Opinion in Structural Biology 42, pp. 83 - 89 (2017)

MPG.PuRe

60.

Journal Article

Fischer, N.; Neumann, P.; Bock, l. V.; Maracci, C.; Wang, Z.; Paleskava, A.; Konevega, A. L.; Schröder, G. F.; Grubmüller, H.; Ficner, R. et al.; Rodnina, M. V.; Stark, H.: The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature 540 (7631), pp. 80 - 85 (2016)

MPG.PuRe

61.

Journal Article

Haag, S.; Sloan, K. E.; Ranjan, N.; Warda, A. S.; Kretschmer, J.; Blessing, C.; Hübner, B.; Seikowski, J.; Dennerlein, S.; Rehling, P. et al.; Rodnina, M. V.; Höbartner, C.; Bohnsack, M. T.: NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. The EMBO Journal 35 (19), pp. 2104 - 2119 (2016)

MPG.PuRe

62.

Journal Article

Draycheva, A.; Bornemann, T.; Ryazanov, S.; Lakomek, N. A.; Wintermeyer, W.: The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 102 (1), pp. 152 - 167 (2016)

MPG.PuRe

63.

Journal Article

Sharma, H.; Adio, S.; Senyushkina, T.; Belardinelli, R.; Peske, F.; Rodnina, M. V.: Kinetics of spontaneous and EF-G-accelerated rotation of ribosomal subunits. Cell Reports 16 (8), pp. 2187 - 2196 (2016)

MPG.PuRe

64.

Journal Article

Lakomek, N. A.; Draycheva, A.; Bornemann, T.; Wintermeyer, W.: Electrostatics and intrinsic disorder drive translocon binding of the SRP receptor FtsY. Angewandte Chemie International Edition 55 (33), pp. 9544 - 9547 (2016)

MPG.PuRe

65.

Journal Article

Maracci, C.; Rodnina, M. V.: Translational GTPases. Biopolymers 105 (8), pp. 463 - 475 (2016)

MPG.PuRe

66.

Journal Article

Rodnina, M. V.: The ribosome in action: Tuning of translational efficiency and protein folding. Protein Science 25 (8), pp. 1390 - 1406 (2016)

MPG.PuRe

67.

Journal Article

Katoh, T.; Wohlgemuth, I.; Nagano, M.; Rodnina, M. V.; Suga, H.: Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling. Nature Communications 7, 11657 (2016)

MPG.PuRe

68.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: Protein elongation, co-translational folding and targeting. Journal of Molecular Biology 428 (10, P. B), pp. 2165 - 2185 (2016)

MPG.PuRe

69.

Journal Article

Fabbretti, A.; Schedlbauer, A.; Brandi, L.; Kaminishi, T.; Giuliodori, A. M.; Garofalo, R.; Ochoa-Lizarralde, B.; Takemoto, C.; Yokoyama, S.; Connell, S. R. et al.; Gualerzi, C. O.; Fucini, P.: Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proceedings of the National Academy of Sciences of the United States of America 113 (16), pp. E2286 - E2295 (2016)

MPG.PuRe

70.

Journal Article

Belardinelli, R.; Sharma, H.; Caliskan, N.; da Cunha, C. E. L.; Peske, F.; Wintermeyer, W.; Rodnina, M. V.: Choreography of molecular movements during ribosome progression along mRNA. Nature Structural and Molecular Biology 23 (4), pp. 342 - 348 (2016)

MPG.PuRe

71.

Journal Article

Buhr, F.; Jha, S.; Thommen, M.; Mittelstät, J.; Kutz, F.; Schwalbe, H.; Rodnina, M. V.; Komar, A. A.: Synonymous codons direct cotranslational folding toward different protein conformations. Molecular Cell 61 (3), pp. 341 - 351 (2016)

MPG.PuRe

72.

Journal Article

Ranjan, N.; Rodnina, M. V.: tRNA wobble modifications and protein homeostasis. Translation 4 (1), e1143076 (2016)

MPG.PuRe

73.

Journal Article

Belardinelli, R.; Sharma, H.; Peske, F.; Wintermeyer, W.; Rodnina, M. V.: Translocation as continuous movement through the ribosome. RNA Biology 13 (12), pp. 1197 - 1203 (2016)

MPG.PuRe

74.

Journal Article

Goyal, A.; Belardinelli, R.; Maracci, C.; Milon, P.; Rodnina, M. V.: Directional transition from initiation to elongation in bacterial translation. Nucleic Acids Research 43 (22), pp. 10700 - 10712 (2015)

MPG.PuRe

75.

Journal Article

Druzhinin, S. I.; Galievsky, V. A.; Demeter, A.; Kovalenko, S. A.; Senyushkina, T.; Dubbaka, S. R.; Knoche, P.; Mayer, P.; Grosse, C.; Stalke, D. et al.; Zachariasse, K. A.: Two-state intramolecular charge transfer (ICT) with 3,5-dimethyl-4(dimethylamino)benzonitrile (MMD) and its meta-isomer mMMD. Ground state amino twist not essential for ICT. Journal of Physical Chemistry A 119 (49), pp. 11820 - 11836 (2015)

MPG.PuRe

76.

Journal Article

Maracci, C.; Wohlgemuth, I.; Rodnina, M. V.: Activities of the peptidyl transferase center of ribosomes lacking protein L27. RNA 21 (12), pp. 2047 - 2052 (2015)

MPG.PuRe

77.

Journal Article

Holtkamp, W.; Kokic, G.; Jäger, M.; Mittelstät, J.; Komar, A.; Rodnina, M. V.: Cotranslational protein folding on the ribosome monitored in real time. Science 250 (6264), pp. 1104 - 1107 (2015)

MPG.PuRe

78.

Journal Article

Dörfel, L. K.; Wohlgemuth, I.; Kubyshkin, V.; Starosta, A. L.; Wilson, D. N.; Budisa, N.; Rodnina, M. V.: Entropic contribution of elongation factor P to proline positioning at the catalytic center of the ribosome. Journal of the American Chemical Society 137 (40), pp. 12997 - 13006 (2015)

MPG.PuRe

79.

Journal Article

Kuhn, P.; Draycheva, A.; Vogt, A.; Petriman, N. A.; Sturm, L.; Drepper, F.; Warscheid, B.; Wintermeyer, W.; Koch, H. G.: Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon. Journal of Cell Biology 211 (1), pp. 91 - 104 (2015)

MPG.PuRe

80.

Journal Article

Kotini, S. B.; Peske, F.; Rodnina, M. V.: Partitioning between recoding and termination at a stop codon-selenocysteine insertion sequence. Nucleic Acids Research 43 (13), pp. 6426 - 6438 (2015)

MPG.PuRe

81.

Journal Article

Adio, S.; Senyushkina, T.; Peske, F.; Fischer, N.; Wintermeyer, W.; Rodnina, M. V.: Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nature Communications 6, 7442 (2015)

MPG.PuRe

82.

Journal Article

Byrne, R. T.; Jenkins, H. T.; Peters, D. T.; Whelan, F.; Stowell, J.; Aziz, N.; Kasatzky, P.; Rodnina, M. V.; Koonin, E. V.; Konevega, A. L. et al.; Antson, A. A.: Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proceedings of the National Academy of Sciences of the United States of America 112 (19), pp. 6033 - 6037 (2015)

MPG.PuRe

83.

Journal Article

Caliskan, N.; Peske, F.; Rodnina, M. V.: Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting. Trends in Biochemical Sciences 40 (5), pp. 265 - 274 (2015)

MPG.PuRe

84.

Journal Article

Fischer, N.; Neumann, P.; Konevega, A. L.; Bock, L. V.; Ficner, R.; Rodnina, M. V.; Stark, H.: Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 520 (7548), pp. 567 - 570 (2015)

MPG.PuRe

85.

Journal Article

Wohlgemuth, I.; Lenz, C.; Urlaub, H.: Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 15 (5-6), pp. 862 - 879 (2015)

MPG.PuRe

86.

Journal Article

Polikanov, Y. S.; Osterman, I. A.; Szal, T.; Tashlitsky, V. N.; Serebryakova, M. V.; Kusochek, P.; Bulkley, D.; Malanicheva, I. A.; Efimenko, T. A.; Efremenkova, O. V. et al.; Konevega, A. L.; Shaw, k.J.; Bogdanov, A. A.; Rodnina, M. V.; Dontsova, O. A.; Mankin, A. S.; Steitz, T. A.; Sergiev, P. V.: Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell 56 (4), pp. 531 - 540 (2014)

MPG.PuRe

87.

Journal Article

Rudorf, S.; Thommen, M.; Rodnina, M. V.; Lipowsky, R.: Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro. PLoS Computational Biology 10 (10), e1003909 (2014)

MPG.PuRe

88.

Journal Article

Ge, Y.; Draycheva, A.; Bornemann, T.; Rodnina, M. V.; Wintermeyer, W.: Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion. Nature Communications 5, 5263 (2014)

MPG.PuRe

89.

Journal Article

Maracci, C.; Peske, F.; Dannies, E.; Pohl, C.; Rodnina, M. V.: Ribosome-induced tuning of GTP hydrolysis by a translational GTPase. Proceedings of the National Academy of Sciences of the United States of America 111 (40), pp. 14418 - 14423 (2014)

MPG.PuRe

90.

Journal Article

Holtkamp, W.; Wintermeyer, W.; Rodnina, M. V.: Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis. BioEssays 36 (10), pp. 908 - 918 (2014)

MPG.PuRe

copyright-transfer-agreement

91.

Journal Article

Garreau de Loubresse, N.; Prokhorova, I.; Holtkamp, W.; Rodnina, M. V.; Yusupova , G.; Yusupov, M.: Structural basis for the inhibition of the eukaryotic ribosome. Nature 513 (7519), pp. 517 - 522 (2014)

MPG.PuRe

92.

Journal Article

Samatova, E. N.; Konevega, A. L.; Wills, N. M.; Atkins, J. F.; Rodnina, M. V.: High-efficiency translational bypassing of non-coding nucleotides specified by mRNA structure and nascent peptide. Nature communications 5, 4459 (2014)

MPG.PuRe

93.

Journal Article

Caliskan, N.; Katunin, V. I.; Belardinelli, R.; Peske, F.; Rodnina, M. V.: Programmed –1 frameshifting by kinetic partitioning during impeded translocation. Cell 157 (7), pp. 1619 - 1631 (2014)

MPG.PuRe

94.

Journal Article

Bornemann, T.; Holtkamp, W.; Wintermeyer, W.: Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 5, 4180 (2014)

MPG.PuRe

95.

Journal Article

Holtkamp, W.; da Cunha, C. E. L.; Peske, F.; Konevega, A. L.; Wintermeyer, W.; Rodnina, M. V.: GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 33 (9), pp. 1073 - 1085 (2014)

MPG.PuRe

96.

Journal Article

Peske, F.; Kuhlenkötter, S.; Rodnina, M. V.; Wintermeyer, W.: Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 42 (3), pp. 1812 - 1820 (2014)

MPG.PuRe

97.

Journal Article

Bock, L. V.; Blau, C.; Schröder, G. F.; Davydov, I. I.; Fischer, N.; Stark, H.; Rodnina, M. V.; Vaiana, A. C.; Grubmüller, H.: Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 20 (12), pp. 1390 - 1396 (2013)

MPG.PuRe

98.

Journal Article

Dörfel, L. K.; Rodnina, M. V.: Elongation factor P: Function and effects on bacterial fitness. Biopolymers 99 (11), pp. 837 - 845 (2013)

MPG.PuRe

99.

Journal Article

Mittelstät, J.; Konevega, A. L.; Rodnina, M. V.: A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. Journal of the American Chemical Society 135 (45), pp. 17031 - 17038 (2013)

MPG.PuRe

100.

Journal Article

Rodnina, M. V.: The ribosome as a versatile catalyst: Reactions at the peptidyl transferase center. Current Opinion in Structural Biology 23 (4), pp. 595 - 602 (2013)

MPG.PuRe