Publikationen
Zeitschriftenartikel (241)
1.
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Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity. EMBO Journal 42 (2), e112372 (2023)
2.
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Translation factor accelerating peptide bond formation on the ribosome: EF-P and eIF5A as entropic catalysts and a potential drug targets. BBA Advances 3, 100074 (2023)
3.
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Ribosome selectivity and nascent chain context in modulating the incorporation of fluorescent non-canonical amino acid into proteins. Scientific Reports 12, 12848 (2022)
4.
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Altered tRNA dynamics during translocation on slippery mRNA as determinant of spontaneous ribosome frameshifting. Nature Communications 13, 4231 (2022)
5.
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Mutagenic analysis of the HIV restriction factor shiftless. Viruses 14 (7), 1454 (2022)
6.
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Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research 50 (9), S. 5282 - 5298 (2022)
7.
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Cotranslational biogenesis of membrane proteins in bacteria. Frontiers in Molecular Biosciences 9, 871121 (2022)
8.
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A switch from α‐helical to β‐strand conformation during co‐translational protein folding. The EMBO Journal 41 (4), e109175 (2022)
9.
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Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor. Nucleic Acids Research 50 (11), S. 6001 - 6019 (2022)
10.
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Kinetic control of nascent protein biogenesis by peptide deformylase. Scientific Reports 11, 24457 (2021)
11.
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Structural mechanism of GTPase-powered ribosome-tRNA movement. Nature Communications 12 (1), 5933 (2021)
12.
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Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation. RNA 27 (9), S. 981 - 990 (2021)
13.
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Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. Journal of Biological Chemistry 297 (1), 100829 (2021)
14.
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Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion. Proceedings of the National Academy of Sciences of the USA 118 (26), e2100474118 (2021)
15.
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Translation error clusters induced by aminoglycoside antibiotics. Nature Communications 12, 1830 (2021)
16.
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Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation. EMBO Journal 40 (6), e106449 (2021)
17.
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Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast. Nature Communications 12, 782 (2021)
18.
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Translational control by ribosome pausing in bacteria: How a non-uniform pace of translation affects protein production and folding. Frontiers in Microbiology 11, 619430 (2021)
19.
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Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. Nucleic Acids Research 48 (22), S. 12929 - 12942 (2020)
20.
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Gradual compaction of nascent peptide during cotranslational folding on the ribosome. eLife 9, e60895 (2020)
21.
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Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nature Communications 11, 4106 (2020)
22.
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Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 39 (15), e104054 (2020)
23.
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Polysomes bypass a 50-nucleotide coding gap less efficiently than monosomes due to attenuation of a 5′ mRNA stem–loop and enhanced drop-off. Journal of Molecular Biology 432 (16), S. 4369 - 4387 (2020)
24.
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Translational recoding: Canonical translation mechanisms reinterpreted. Nucleic Acids Research 48 (3), S. 1056 - 1067 (2020)
25.
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Cotranslational folding of proteins on the ribosome. Biomolecules 10 (1), 97 (2020)
26.
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Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 5 (12), eaax8030 (2019)
27.
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Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 401 (1), S. 131 - 142 (2019)
28.
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Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 10, 4598 (2019)
29.
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Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 593 (13), S. 1468 - 1482 (2019)
30.
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The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 593 (13), S. 1483 - 1493 (2019)
31.
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EF-G-induced ribosome sliding along the noncoding mRNA. Science Advances 5 (6), eaaw9049 (2019)
32.
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Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance. Nucleic Acids Research 47 (10), S. 5210 - 5222 (2019)
33.
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Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3. Nucleic Acids Research 47 (9), S. 4798 - 4813 (2019)
34.
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Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 47 (6), S. 2932 - 2945 (2019)
35.
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Elongation factor Tu's nucleotide binding is governed by a thermodynamic landscape unique among bacterial translation factors. Journal of the American Chemical Society 141 (26), S. 10236 - 10246 (2019)
36.
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Decomposition of time-dependent fluorescence signals reveals codon-specific kinetics of protein synthesis. Nucleic Acids Research 46 (22), e130 (2018)
37.
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Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting. Nucleic Acids Research 46 (16), S. 8079 - 8089 (2018)
38.
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Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2. Genes and Development 32 (17-18), S. 1226 - 1241 (2018)
39.
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Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nature Communications 9, 3053 (2018)
40.
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Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon. Scientific Reports 8 (1), 9922 (2018)
41.
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Co-translational folding trajectory of the HemK helical domain. Biochemistry 57 (25), S. 3460 - 3464 (2018)
42.
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Dynamics of ribosomes and release factors during translation termination in E-coli. eLife 7, e34252 (2018)
43.
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Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA. Proceedings of the National Academy of Sciences of the United States of America 115 (17), S. 4411 - 4416 (2018)
44.
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Translation in prokaryotes. Cold Spring Harbor Perspectives in Biology 10 (9), a032664 (2018)
45.
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Deciphering the reading of the genetic code by near-cognate tRNA. Proceedings of the National Academy of Sciences of the United States of America 115 (12), S. 3018 - 3023 (2018)
46.
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Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence. Nucleic Acids Research 45 (20), S. 11858 - 11866 (2017)
47.
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Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P. Molecular Cell 68 (3), S. 515 - 527 (2017)
48.
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Non-canonical binding site for bacterial initiation factor 3 on the large ribosomal subunit. Cell Reports 20 (13), S. 3113 - 3122 (2017)
49.
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Effect of fusidic acid on the kinetics of molecular motions during EF-G-induced translocation on the ribosome. Scientific Reports 7, 10536 (2017)
50.
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An antimicrobial peptide that inhibits translation by trapping release factor trap. Nature Structural and Molecular Biology 24 (9), S. 752 - 757 (2017)
51.
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Ribosome rearrangements at the onset of translational bypassing. Science Advances 3 (6), e1700147 (2017)
52.
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Conditional switch between frameshifting regimes upon translation of dnaX mRNA. Molecular Cell 66 (4), S. 558 - 567 (2017)
53.
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Signal recognition particle prevents N-terminal processing of bacterial membrane proteins. Nature Communications 8, 15562 (2017)
54.
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Thio-modification of tRNA at the wobble position as regulator of the kinetics of decoding and translocation on the ribosome. Journal of the American Chemical Society 139 (16), S. 5857 - 5864 (2017)
55.
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Ribosome dynamics during decoding. Philosophical Transactions of the Royal Society B 372 (1716), 20160182 (2017)
56.
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Co-translational protein folding: Progress and methods. Current Opinion in Structural Biology 42, S. 83 - 89 (2017)
57.
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The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature 540 (7631), S. 80 - 85 (2016)
58.
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NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. The EMBO Journal 35 (19), S. 2104 - 2119 (2016)
59.
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The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 102 (1), S. 152 - 167 (2016)
60.
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Kinetics of spontaneous and EF-G-accelerated rotation of ribosomal subunits. Cell Reports 16 (8), S. 2187 - 2196 (2016)
61.
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Electrostatics and intrinsic disorder drive translocon binding of the SRP receptor FtsY. Angewandte Chemie International Edition 55 (33), S. 9544 - 9547 (2016)
62.
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Translational GTPases. Biopolymers 105 (8), S. 463 - 475 (2016)
63.
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The ribosome in action: Tuning of translational efficiency and protein folding. Protein Science 25 (8), S. 1390 - 1406 (2016)
64.
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Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling. Nature Communications 7, 11657 (2016)
65.
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Protein elongation, co-translational folding and targeting. Journal of Molecular Biology 428 (10, P. B), S. 2165 - 2185 (2016)
66.
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Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proceedings of the National Academy of Sciences of the United States of America 113 (16), S. E2286 - E2295 (2016)
67.
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Choreography of molecular movements during ribosome progression along mRNA. Nature Structural and Molecular Biology 23 (4), S. 342 - 348 (2016)
68.
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Synonymous codons direct cotranslational folding toward different protein conformations. Molecular Cell 61 (3), S. 341 - 351 (2016)
69.
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tRNA wobble modifications and protein homeostasis. Translation 4 (1), e1143076 (2016)
70.
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Translocation as continuous movement through the ribosome. RNA Biology 13 (12), S. 1197 - 1203 (2016)
71.
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Directional transition from initiation to elongation in bacterial translation. Nucleic Acids Research 43 (22), S. 10700 - 10712 (2015)
72.
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Two-state intramolecular charge transfer (ICT) with 3,5-dimethyl-4(dimethylamino)benzonitrile (MMD) and its meta-isomer mMMD. Ground state amino twist not essential for ICT. Journal of Physical Chemistry A 119 (49), S. 11820 - 11836 (2015)
73.
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Activities of the peptidyl transferase center of ribosomes lacking protein L27. RNA 21 (12), S. 2047 - 2052 (2015)
74.
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Cotranslational protein folding on the ribosome monitored in real time. Science 250 (6264), S. 1104 - 1107 (2015)
75.
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Entropic contribution of elongation factor P to proline positioning at the catalytic center of the ribosome. Journal of the American Chemical Society 137 (40), S. 12997 - 13006 (2015)
76.
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Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon. Journal of Cell Biology 211 (1), S. 91 - 104 (2015)
77.
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Partitioning between recoding and termination at a stop codon-selenocysteine insertion sequence. Nucleic Acids Research 43 (13), S. 6426 - 6438 (2015)
78.
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Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nature Communications 6, 7442 (2015)
79.
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Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proceedings of the National Academy of Sciences of the United States of America 112 (19), S. 6033 - 6037 (2015)
80.
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Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting. Trends in Biochemical Sciences 40 (5), S. 265 - 274 (2015)
81.
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Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 520 (7548), S. 567 - 570 (2015)
82.
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Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 15 (5-6), S. 862 - 879 (2015)
83.
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Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell 56 (4), S. 531 - 540 (2014)
84.
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Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro. PLoS Computational Biology 10 (10), e1003909 (2014)
85.
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Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion. Nature Communications 5, 5263 (2014)
86.
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Ribosome-induced tuning of GTP hydrolysis by a translational GTPase. Proceedings of the National Academy of Sciences of the United States of America 111 (40), S. 14418 - 14423 (2014)
87.
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Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis. BioEssays 36 (10), S. 908 - 918 (2014)
88.
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Structural basis for the inhibition of the eukaryotic ribosome. Nature 513 (7519), S. 517 - 522 (2014)
89.
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High-efficiency translational bypassing of non-coding nucleotides specified by mRNA structure and nascent peptide. Nature communications 5, 4459 (2014)
90.
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Programmed –1 frameshifting by kinetic partitioning during impeded translocation. Cell 157 (7), S. 1619 - 1631 (2014)
91.
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Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 5, 4180 (2014)
92.
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GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 33 (9), S. 1073 - 1085 (2014)
93.
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Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 42 (3), S. 1812 - 1820 (2014)
94.
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Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 20 (12), S. 1390 - 1396 (2013)
95.
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Elongation factor P: Function and effects on bacterial fitness. Biopolymers 99 (11), S. 837 - 845 (2013)
96.
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A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. Journal of the American Chemical Society 135 (45), S. 17031 - 17038 (2013)
97.
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The ribosome as a versatile catalyst: Reactions at the peptidyl transferase center. Current Opinion in Structural Biology 23 (4), S. 595 - 602 (2013)
98.
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tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding. Proceedings of the National Academy of Sciences of the United States of America 110 (30), S. 12289 - 12294 (2013)
99.
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Translocation in action. Science 340 (6140), S. 1534 - 1535 (2013)