Publikationen
Zeitschriftenartikel (261)
1.
Zeitschriftenartikel
Identification of the lydiamycin biosynthetic gene cluster in a plant pathogen guides structural revision and identification of molecular target. Proceedings of the National Academy of Sciences of the United States of America 122 (21), e2424388122 (2025)
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Translation dysregulation in cancer as a source for targetable antigens. Cancer Cell 43 (5), S. 823 - 840.e18 (2025)
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Modulation of protein activity by small RNA base pairing internal to coding sequences. Molecular Cell 85 (9), S. 1824 - 1837.e7 (2025)
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Structural basis for translational control by the human 48S initiation complex. Nature Structural & Molecular Biology 32, S. 62 - 72 (2025)
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Phosphorylation of P-stalk proteins defines the ribosomal state for interaction with auxiliary protein factors. EMBO Reports 25, S. 5478 - 5506 (2024)
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Kinetic mechanism and determinants of EF-P recruitment to translating ribosomes. Nucleic Acids Research 52 (19), S. 11870 - 11883 (2024)
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Cooperation of regulatory RNA and the RNA degradosome in transcript surveillance. Nucleic Acids Research 52 (15), S. 9161 - 9173 (2024)
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Sophisticated natural products as antibiotics. Nature 632 (8023), S. 39 - 49 (2024)
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Translation Rates and Protein Folding. Journal of Molecular Biology 436 (14), 168384 (2024)
10.
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Interferon-Stimulated Genes that Target Retrovirus Translation. Viruses 16 (6), 933 (2024)
11.
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Kinetics of programmed and spontaneous ribosome sliding along the mRNA. Nucleic Acids Research 52 (11), S. 6507 - 6517 (2024)
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Decomposing bulk signals to reveal hidden information in processive enzyme reactions: A case study in mRNA translation. PLOS Computational Biology 20 (3), e1011918 (2024)
13.
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Peptidyl-tRNA hydrolase as a key player in the liberation of truncated nascent chains from the ribosomal subunit. Molecular Cell 84 (4), S. 614 - 615 (2024)
14.
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How the ribosome shapes cotranslational protein folding. Current Opinion in Structural Biology 84, 102740 (2024)
15.
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The Inhibition of Gag-Pol Expression by the Restriction Factor Shiftless Is Dispensable for the Restriction of HIV-1 Infection. Viruses 16 (4), 583 (2024)
16.
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Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications. ACS Chemical Biology 18 (12), S. 2441 - 2449 (2023)
17.
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Lost and Found in Translation: Why Ribosomal Frameshifting Might Be the Next Antiviral Target. Resonance 28 (9), S. 1391 - 1400 (2023)
18.
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Modulation of translational decoding by m6A modification of mRNA. Nature Communications 14, 4784 (2023)
19.
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Decoding and Recoding of mRNA Sequences by the Ribosome. Annual Review of Biophysics 52, S. 161 - 182 (2023)
20.
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The many faces of ribosome translocation along the mRNA: reading frame maintenance, ribosome frameshifting and translational bypassing. Biological Chemistry 404 (8-9), S. 755 - 767 (2023)
21.
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Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity. EMBO Journal 42 (2), e112372 (2023)
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Translation factor accelerating peptide bond formation on the ribosome: EF-P and eIF5A as entropic catalysts and a potential drug targets. BBA Advances 3, 100074 (2023)
23.
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Ribosome selectivity and nascent chain context in modulating the incorporation of fluorescent non-canonical amino acid into proteins. Scientific Reports 12, 12848 (2022)
24.
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Altered tRNA dynamics during translocation on slippery mRNA as determinant of spontaneous ribosome frameshifting. Nature Communications 13, 4231 (2022)
25.
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Mutagenic analysis of the HIV restriction factor shiftless. Viruses 14 (7), 1454 (2022)
26.
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Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research 50 (9), S. 5282 - 5298 (2022)
27.
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Cotranslational biogenesis of membrane proteins in bacteria. Frontiers in Molecular Biosciences 9, 871121 (2022)
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A switch from α‐helical to β‐strand conformation during co‐translational protein folding. The EMBO Journal 41 (4), e109175 (2022)
29.
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Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor. Nucleic Acids Research 50 (11), S. 6001 - 6019 (2022)
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Kinetic control of nascent protein biogenesis by peptide deformylase. Scientific Reports 11, 24457 (2021)
31.
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Structural mechanism of GTPase-powered ribosome-tRNA movement. Nature Communications 12 (1), 5933 (2021)
32.
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Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation. RNA 27 (9), S. 981 - 990 (2021)
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Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. Journal of Biological Chemistry 297 (1), 100829 (2021)
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Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion. Proceedings of the National Academy of Sciences of the USA 118 (26), e2100474118 (2021)
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Translation error clusters induced by aminoglycoside antibiotics. Nature Communications 12, 1830 (2021)
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Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation. EMBO Journal 40 (6), e106449 (2021)
37.
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Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast. Nature Communications 12, 782 (2021)
38.
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Translational control by ribosome pausing in bacteria: How a non-uniform pace of translation affects protein production and folding. Frontiers in Microbiology 11, 619430 (2021)
39.
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Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. Nucleic Acids Research 48 (22), S. 12929 - 12942 (2020)
40.
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Gradual compaction of nascent peptide during cotranslational folding on the ribosome. eLife 9, e60895 (2020)
41.
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Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nature Communications 11, 4106 (2020)
42.
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Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 39 (15), e104054 (2020)
43.
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Polysomes bypass a 50-nucleotide coding gap less efficiently than monosomes due to attenuation of a 5′ mRNA stem–loop and enhanced drop-off. Journal of Molecular Biology 432 (16), S. 4369 - 4387 (2020)
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Translational recoding: Canonical translation mechanisms reinterpreted. Nucleic Acids Research 48 (3), S. 1056 - 1067 (2020)
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Cotranslational folding of proteins on the ribosome. Biomolecules 10 (1), 97 (2020)
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Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 5 (12), eaax8030 (2019)
47.
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Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 401 (1), S. 131 - 142 (2019)
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Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 10, 4598 (2019)
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Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 593 (13), S. 1468 - 1482 (2019)
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The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 593 (13), S. 1483 - 1493 (2019)