Publications
Journal Article (241)
1.
Journal Article
42 (2), e112372 (2023)
Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity. EMBO Journal 2.
Journal Article
3, 100074 (2023)
Translation factor accelerating peptide bond formation on the ribosome: EF-P and eIF5A as entropic catalysts and a potential drug targets. BBA Advances 3.
Journal Article
12, 12848 (2022)
Ribosome selectivity and nascent chain context in modulating the incorporation of fluorescent non-canonical amino acid into proteins. Scientific Reports 4.
Journal Article
13, 4231 (2022)
Altered tRNA dynamics during translocation on slippery mRNA as determinant of spontaneous ribosome frameshifting. Nature Communications 5.
Journal Article
14 (7), 1454 (2022)
Mutagenic analysis of the HIV restriction factor shiftless. Viruses 6.
Journal Article
50 (9), pp. 5282 - 5298 (2022)
Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research 7.
Journal Article
9, 871121 (2022)
Cotranslational biogenesis of membrane proteins in bacteria. Frontiers in Molecular Biosciences 8.
Journal Article
41 (4), e109175 (2022)
A switch from α‐helical to β‐strand conformation during co‐translational protein folding. The EMBO Journal 9.
Journal Article
50 (11), pp. 6001 - 6019 (2022)
Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor. Nucleic Acids Research 10.
Journal Article
11, 24457 (2021)
Kinetic control of nascent protein biogenesis by peptide deformylase. Scientific Reports 11.
Journal Article
12 (1), 5933 (2021)
Structural mechanism of GTPase-powered ribosome-tRNA movement. Nature Communications 12.
Journal Article
27 (9), pp. 981 - 990 (2021)
Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation. RNA 13.
Journal Article
297 (1), 100829 (2021)
Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. Journal of Biological Chemistry 14.
Journal Article
118 (26), e2100474118 (2021)
Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion. Proceedings of the National Academy of Sciences of the USA 15.
Journal Article
12, 1830 (2021)
Translation error clusters induced by aminoglycoside antibiotics. Nature Communications 16.
Journal Article
40 (6), e106449 (2021)
Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation. EMBO Journal 17.
Journal Article
12, 782 (2021)
Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast. Nature Communications 18.
Journal Article
11, 619430 (2021)
Translational control by ribosome pausing in bacteria: How a non-uniform pace of translation affects protein production and folding. Frontiers in Microbiology 19.
Journal Article
48 (22), pp. 12929 - 12942 (2020)
Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. Nucleic Acids Research 20.
Journal Article
9, e60895 (2020)
Gradual compaction of nascent peptide during cotranslational folding on the ribosome. eLife 21.
Journal Article
11, 4106 (2020)
Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nature Communications 22.
Journal Article
39 (15), e104054 (2020)
Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 23.
Journal Article
432 (16), pp. 4369 - 4387 (2020)
Polysomes bypass a 50-nucleotide coding gap less efficiently than monosomes due to attenuation of a 5′ mRNA stem–loop and enhanced drop-off. Journal of Molecular Biology 24.
Journal Article
48 (3), pp. 1056 - 1067 (2020)
Translational recoding: Canonical translation mechanisms reinterpreted. Nucleic Acids Research 25.
Journal Article
10 (1), 97 (2020)
Cotranslational folding of proteins on the ribosome. Biomolecules 26.
Journal Article
5 (12), eaax8030 (2019)
Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 27.
Journal Article
401 (1), pp. 131 - 142 (2019)
Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 28.
Journal Article
10, 4598 (2019)
Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 29.
Journal Article
593 (13), pp. 1468 - 1482 (2019)
Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 30.
Journal Article
593 (13), pp. 1483 - 1493 (2019)
The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 31.
Journal Article
5 (6), eaaw9049 (2019)
EF-G-induced ribosome sliding along the noncoding mRNA. Science Advances 32.
Journal Article
47 (10), pp. 5210 - 5222 (2019)
Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance. Nucleic Acids Research 33.
Journal Article
47 (9), pp. 4798 - 4813 (2019)
Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3. Nucleic Acids Research 34.
Journal Article
47 (6), pp. 2932 - 2945 (2019)
Broad range of missense error frequencies in cellular proteins. Nucleic Acids Research 35.
Journal Article
141 (26), pp. 10236 - 10246 (2019)
Elongation factor Tu's nucleotide binding is governed by a thermodynamic landscape unique among bacterial translation factors. Journal of the American Chemical Society 36.
Journal Article
46 (22), e130 (2018)
Decomposition of time-dependent fluorescence signals reveals codon-specific kinetics of protein synthesis. Nucleic Acids Research 37.
Journal Article
46 (16), pp. 8079 - 8089 (2018)
Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting. Nucleic Acids Research 38.
Journal Article
32 (17-18), pp. 1226 - 1241 (2018)
Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2. Genes and Development 39.
Journal Article
9, 3053 (2018)
Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nature Communications 40.
Journal Article
8 (1), 9922 (2018)
Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon. Scientific Reports 41.
Journal Article
57 (25), pp. 3460 - 3464 (2018)
Co-translational folding trajectory of the HemK helical domain. Biochemistry 42.
Journal Article
7, e34252 (2018)
Dynamics of ribosomes and release factors during translation termination in E-coli. eLife 43.
Journal Article
115 (17), pp. 4411 - 4416 (2018)
Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA. Proceedings of the National Academy of Sciences of the United States of America 44.
Journal Article
10 (9), a032664 (2018)
Translation in prokaryotes. Cold Spring Harbor Perspectives in Biology 45.
Journal Article
115 (12), pp. 3018 - 3023 (2018)
Deciphering the reading of the genetic code by near-cognate tRNA. Proceedings of the National Academy of Sciences of the United States of America 46.
Journal Article
45 (20), pp. 11858 - 11866 (2017)
Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence. Nucleic Acids Research 47.
Journal Article
68 (3), pp. 515 - 527 (2017)
Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P. Molecular Cell 48.
Journal Article
20 (13), pp. 3113 - 3122 (2017)
Non-canonical binding site for bacterial initiation factor 3 on the large ribosomal subunit. Cell Reports 49.
Journal Article
7, 10536 (2017)
Effect of fusidic acid on the kinetics of molecular motions during EF-G-induced translocation on the ribosome. Scientific Reports 50.
Journal Article
24 (9), pp. 752 - 757 (2017)
An antimicrobial peptide that inhibits translation by trapping release factor trap. Nature Structural and Molecular Biology 51.
Journal Article
3 (6), e1700147 (2017)
Ribosome rearrangements at the onset of translational bypassing. Science Advances 52.
Journal Article
66 (4), pp. 558 - 567 (2017)
Conditional switch between frameshifting regimes upon translation of dnaX mRNA. Molecular Cell 53.
Journal Article
8, 15562 (2017)
Signal recognition particle prevents N-terminal processing of bacterial membrane proteins. Nature Communications 54.
Journal Article
139 (16), pp. 5857 - 5864 (2017)
Thio-modification of tRNA at the wobble position as regulator of the kinetics of decoding and translocation on the ribosome. Journal of the American Chemical Society 55.
Journal Article
372 (1716), 20160182 (2017)
Ribosome dynamics during decoding. Philosophical Transactions of the Royal Society B 56.
Journal Article
42, pp. 83 - 89 (2017)
Co-translational protein folding: Progress and methods. Current Opinion in Structural Biology 57.
Journal Article
540 (7631), pp. 80 - 85 (2016)
The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature 58.
Journal Article
35 (19), pp. 2104 - 2119 (2016)
NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation. The EMBO Journal 59.
Journal Article
102 (1), pp. 152 - 167 (2016)
The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 60.
Journal Article
16 (8), pp. 2187 - 2196 (2016)
Kinetics of spontaneous and EF-G-accelerated rotation of ribosomal subunits. Cell Reports 61.
Journal Article
55 (33), pp. 9544 - 9547 (2016)
Electrostatics and intrinsic disorder drive translocon binding of the SRP receptor FtsY. Angewandte Chemie International Edition 62.
Journal Article
105 (8), pp. 463 - 475 (2016)
Translational GTPases. Biopolymers 63.
Journal Article
25 (8), pp. 1390 - 1406 (2016)
The ribosome in action: Tuning of translational efficiency and protein folding. Protein Science 64.
Journal Article
7, 11657 (2016)
Essential structural elements in tRNAPro for EF-P-mediated alleviation of translation stalling. Nature Communications 65.
Journal Article
428 (10, P. B), pp. 2165 - 2185 (2016)
Protein elongation, co-translational folding and targeting. Journal of Molecular Biology 66.
Journal Article
113 (16), pp. E2286 - E2295 (2016)
Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proceedings of the National Academy of Sciences of the United States of America 67.
Journal Article
23 (4), pp. 342 - 348 (2016)
Choreography of molecular movements during ribosome progression along mRNA. Nature Structural and Molecular Biology 68.
Journal Article
61 (3), pp. 341 - 351 (2016)
Synonymous codons direct cotranslational folding toward different protein conformations. Molecular Cell 69.
Journal Article
4 (1), e1143076 (2016)
tRNA wobble modifications and protein homeostasis. Translation 70.
Journal Article
13 (12), pp. 1197 - 1203 (2016)
Translocation as continuous movement through the ribosome. RNA Biology 71.
Journal Article
43 (22), pp. 10700 - 10712 (2015)
Directional transition from initiation to elongation in bacterial translation. Nucleic Acids Research 72.
Journal Article
119 (49), pp. 11820 - 11836 (2015)
Two-state intramolecular charge transfer (ICT) with 3,5-dimethyl-4(dimethylamino)benzonitrile (MMD) and its meta-isomer mMMD. Ground state amino twist not essential for ICT. Journal of Physical Chemistry A 73.
Journal Article
21 (12), pp. 2047 - 2052 (2015)
Activities of the peptidyl transferase center of ribosomes lacking protein L27. RNA 74.
Journal Article
250 (6264), pp. 1104 - 1107 (2015)
Cotranslational protein folding on the ribosome monitored in real time. Science 75.
Journal Article
137 (40), pp. 12997 - 13006 (2015)
Entropic contribution of elongation factor P to proline positioning at the catalytic center of the ribosome. Journal of the American Chemical Society 76.
Journal Article
211 (1), pp. 91 - 104 (2015)
Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon. Journal of Cell Biology 77.
Journal Article
43 (13), pp. 6426 - 6438 (2015)
Partitioning between recoding and termination at a stop codon-selenocysteine insertion sequence. Nucleic Acids Research 78.
Journal Article
6, 7442 (2015)
Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nature Communications 79.
Journal Article
112 (19), pp. 6033 - 6037 (2015)
Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proceedings of the National Academy of Sciences of the United States of America 80.
Journal Article
40 (5), pp. 265 - 274 (2015)
Changed in translation: mRNA recoding by −1 programmed ribosomal frameshifting. Trends in Biochemical Sciences 81.
Journal Article
520 (7548), pp. 567 - 570 (2015)
Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM. Nature 82.
Journal Article
15 (5-6), pp. 862 - 879 (2015)
Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 83.
Journal Article
56 (4), pp. 531 - 540 (2014)
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell 84.
Journal Article
10 (10), e1003909 (2014)
Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro. PLoS Computational Biology 85.
Journal Article
5, 5263 (2014)
Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion. Nature Communications 86.
Journal Article
111 (40), pp. 14418 - 14423 (2014)
Ribosome-induced tuning of GTP hydrolysis by a translational GTPase. Proceedings of the National Academy of Sciences of the United States of America 87.
Journal Article
36 (10), pp. 908 - 918 (2014)
Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis. BioEssays 88.
Journal Article
513 (7519), pp. 517 - 522 (2014)
Structural basis for the inhibition of the eukaryotic ribosome. Nature 89.
Journal Article
5, 4459 (2014)
High-efficiency translational bypassing of non-coding nucleotides specified by mRNA structure and nascent peptide. Nature communications 90.
Journal Article
157 (7), pp. 1619 - 1631 (2014)
Programmed –1 frameshifting by kinetic partitioning during impeded translocation. Cell 91.
Journal Article
5, 4180 (2014)
Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 92.
Journal Article
33 (9), pp. 1073 - 1085 (2014)
GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 93.
Journal Article
42 (3), pp. 1812 - 1820 (2014)
Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 94.
Journal Article
20 (12), pp. 1390 - 1396 (2013)
Energy barriers and driving forces in tRNA translocation through the ribosome. Nature Structural and Molecular Biology 95.
Journal Article
99 (11), pp. 837 - 845 (2013)
Elongation factor P: Function and effects on bacterial fitness. Biopolymers 96.
Journal Article
135 (45), pp. 17031 - 17038 (2013)
A kinetic safety gate controlling the delivery of unnatural amino acids to the ribosome. Journal of the American Chemical Society 97.
Journal Article
23 (4), pp. 595 - 602 (2013)
The ribosome as a versatile catalyst: Reactions at the peptidyl transferase center. Current Opinion in Structural Biology 98.
Journal Article
110 (30), pp. 12289 - 12294 (2013)
tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding. Proceedings of the National Academy of Sciences of the United States of America 99.
Journal Article
340 (6140), pp. 1534 - 1535 (2013)
Translocation in action. Science