Max Planck Institute for Multidisciplinary Sciences

Publications

Journal Article (260)

1.

Journal Article

Weller, C.; Bartok, O.; McGinnis, C. S.; Palashati, H.; Chang, T.-G.; Malko, D.; Shmueli, M. D.; Nagao, A.; Hayoun, D.; Murayama, A. et al.; Sakaguchi, Y.; Poulis, P.; Khatib, A.; Erlanger Avigdor, B.; Gordon, S.; Cohen Shvefel, S.; Zemanek, M. J.; Nielsen, M. M.; Boura-Halfon, S.; Sagie, S.; Gumpert, N.; Yang, W.; Alexeev, D.; Kyriakidou, P.; Yao, W.; Zerbib, M.; Greenberg, P.; Benedek, G.; Litchfield, K.; Petrovich-Kopitman, E.; Nagler, A.; Oren, R.; Ben-Dor, S.; Levin, Y.; Pilpel, Y.; Rodnina, M. V.; Cox, J.; Merbl, Y.; Satpathy, A. T.; Carmi, Y.; Erhard, F.; Suzuki, T.; Buskirk, A. R.; Olweus, J.; Ruppin, E.; Schlosser, A.; Samuels, Y.: Translation dysregulation in cancer as a source for targetable antigens. Cancer Cell 43 (5), pp. 823 - 840.e18 (2025)

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2.

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Thongdee, N.; Alaniz, M. M.; Samatova, E.; Zhong, A.; Esnault, C.; Zhang, H.; Dale, R. K.; Rodnina, M. V.; Storz, G.: Modulation of protein activity by small RNA base pairing internal to coding sequences. Molecular Cell 85 (9), pp. 1824 - 1837.e7 (2025)

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3.

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Petrychenko, V.; Yi, S.-H.; Liedtke, D.; Peng, B.-Z.; Rodnina, M. V.; Fischer, N.: Structural basis for translational control by the human 48S initiation complex. Nature Structural & Molecular Biology 32, pp. 62 - 72 (2025)

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4.

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Filipek, K.; Blanchet, S.; Molestak, E.; Zaciura, M.; Wu, C. C.-C.; Horbowicz-Drożdżal, P.; Grela, P.; Zalewski, M.; Kmiecik, S.; González-Ibarra, A. et al.; Krokowski, D.; Latoch, P.; Starosta, A. L.; Mołoń, M.; Shao, Y.; Borkiewicz, L.; Michalec-Wawiórka, B.; Wawiórka, L.; Kubiński, K.; Socała, K.; Wlaź, P.; Cunningham, K. W.; Green, R.; Rodnina, M. V.; Tchórzewski, M.: Phosphorylation of P-stalk proteins defines the ribosomal state for interaction with auxiliary protein factors. EMBO Reports 25, pp. 5478 - 5506 (2024)

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5.

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Mudryi, V.; Frister, J. O.; Peng, B.-Z.; Wohlgemuth, I.; Peske, F.; Rodnina, M. V.: Kinetic mechanism and determinants of EF-P recruitment to translating ribosomes. Nucleic Acids Research 52 (19), pp. 11870 - 11883 (2024)

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6.

Journal Article

Bandyra, K. J.; Fröhlich, K. S.; Vogel, J.; Rodnina, M. V.; Goyal, A.; Luisi, B.: Cooperation of regulatory RNA and the RNA degradosome in transcript surveillance. Nucleic Acids Research 52 (15), pp. 9161 - 9173 (2024)

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7.

Journal Article

Lewis, K.; Lee, R. E.; Brötz-Oesterhelt, H.; Hiller, S.; Rodnina, M. V.; Schneider, T.; Weingarth, M.; Wohlgemuth, I.: Sophisticated natural products as antibiotics. Nature 632 (8023), pp. 39 - 49 (2024)

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8.

Journal Article

Komar, A.A.; Samatova, E.; Rodnina, M. V.: Translation Rates and Protein Folding. Journal of Molecular Biology 436 (14), 168384 (2024)

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9.

Journal Article

Jäger, N.; Pöhlmann, S.; Rodnina, M. V.; Ayyub, S. A.: Interferon-Stimulated Genes that Target Retrovirus Translation. Viruses 16 (6), 933 (2024)

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10.

Journal Article

Senyushkina, T.; Samatova, E.; Klimova, M.; Rodnina, M. V.: Kinetics of programmed and spontaneous ribosome sliding along the mRNA. Nucleic Acids Research 52 (11), pp. 6507 - 6517 (2024)

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11.

Journal Article

Haase, N.; Holtkamp, W.; Christ, S.; Heinemann, D.; Rodnina, M. V.; Rudorf, S.: Decomposing bulk signals to reveal hidden information in processive enzyme reactions: A case study in mRNA translation. PLOS Computational Biology 20 (3), e1011918 (2024)

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12.

Journal Article

Rodnina, M. V.: Peptidyl-tRNA hydrolase as a key player in the liberation of truncated nascent chains from the ribosomal subunit. Molecular Cell 84 (4), pp. 614 - 615 (2024)

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13.

Journal Article

Samatova, E.; Komar, A.A.; Rodnina, M. V.: How the ribosome shapes cotranslational protein folding. Current Opinion in Structural Biology 84, 102740 (2024)

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14.

Journal Article

Jäger, N.; Ayyub, S. A.; Peske, F.; Liedtke, D.; Bohne, J.; Hoffmann, M.; Rodnina, M. V.; Pöhlmann, S.: The Inhibition of Gag-Pol Expression by the Restriction Factor Shiftless Is Dispensable for the Restriction of HIV-1 Infection. Viruses 16 (4), 583 (2024)

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15.

Journal Article

Helm, M.; Bohnsack, M.T.; Carell, T.; Dalpke, A.; Entian, K.-D.; Ehrenhofer-Murray, A.; Ficner, R.; Hammann, C.; Höbartner, C.; Jäschke, A. et al.; Jeltsch, A.; Kaiser, S.; Klassen, R.; Leidel, S.A.; Marx, A.; Mörl, M.; Meier, J.C.; Meister, G.; Rentmeister, A.; Rodnina, M. V.; Roignant, J.-Y.; Schaffrath, R.; Stadler, P.; Stafforst, T.: Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications. ACS Chemical Biology 18 (12), pp. 2441 - 2449 (2023)

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16.

Journal Article

Ayyub, S. A.: Lost and Found in Translation: Why Ribosomal Frameshifting Might Be the Next Antiviral Target. Resonance 28 (9), pp. 1391 - 1400 (2023)

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17.

Journal Article

Jain, S.; Koziej, L.; Poulis, P.; Kaczmarczyk, I.; Gaik, M.; Rawski, M.; Ranjan, N.; Glatt, S.; Rodnina, M. V.: Modulation of translational decoding by m⁶A modification of mRNA. Nature Communications 14, 4784 (2023)

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18.

Journal Article

Rodnina, M. V.: Decoding and Recoding of mRNA Sequences by the Ribosome. Annual Review of Biophysics 52, pp. 161 - 182 (2023)

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19.

Journal Article

Poulis, P.; Peske, F.; Rodnina, M. V.: The many faces of ribosome translocation along the mRNA: reading frame maintenance, ribosome frameshifting and translational bypassing. Biological Chemistry 404 (8-9), pp. 755 - 767 (2023)

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20.

Journal Article

Han, W.; Peng, B.-Z.; Wang, C.; Townsend II, G. E.; Barry, N. A.; Peske, F.; Goodman, A. L.; Liu, J.; Rodnina, M. V.; Groisman, E. A.: Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity. EMBO Journal 42 (2), e112372 (2023)

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21.

Journal Article

Mudryi, V.; Peske, F.; Rodnina, M. V.: Translation factor accelerating peptide bond formation on the ribosome: EF-P and eIF5A as entropic catalysts and a potential drug targets. BBA Advances 3, 100074 (2023)

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22.

Journal Article

Thommen, M.; Draycheva, A.; Rodnina, M. V.: Ribosome selectivity and nascent chain context in modulating the incorporation of fluorescent non-canonical amino acid into proteins. Scientific Reports 12, 12848 (2022)

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23.

Journal Article

Poulis, P.; Patel, A.; Rodnina, M. V.; Adio, S.: Altered tRNA dynamics during translocation on slippery mRNA as determinant of spontaneous ribosome frameshifting. Nature Communications 13, 4231 (2022)

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24.

Journal Article

Jäger, N.; Ayyub, S. A.; Korniy, N.; Peske, F.; Hoffmann, M.; Rodnina, M. V.; Pöhlmann, S.: Mutagenic analysis of the HIV restriction factor shiftless. Viruses 14 (7), 1454 (2022)

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25.

Journal Article

Yi, S.-H.; Petrychenko, V.; Schliep, J. E.; Goyal, A.; Linden, A.; Chari, A.; Urlaub, H.; Stark, H.; Rodnina, M. V.; Adio, S. et al.; Fischer, N.: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research 50 (9), pp. 5282 - 5298 (2022)

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26.

Journal Article

Mercier, E.; Wang, X.; Bögeholz, L. A. K.; Wintermeyer, W.; Rodnina, M. V.: Cotranslational biogenesis of membrane proteins in bacteria. Frontiers in Molecular Biosciences 9, 871121 (2022)

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27.

Journal Article

Agirrezabala, X.; Samatova, E.; Macher, M.; Liutkute, M.; Maiti, M.; Gil‐Carton, D.; Novacek, J.; Valle, M.; Rodnina, M. V.: A switch from α‐helical to β‐strand conformation during co‐translational protein folding. The EMBO Journal 41 (4), e109175 (2022)

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28.

Journal Article

Karki, P.; Carney, T. D.; Maracci, C.; Yatsenko, A. S.; Shcherbata, H. R.; Rodnina, M. V.: Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor. Nucleic Acids Research 50 (11), pp. 6001 - 6019 (2022)

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29.

Journal Article

Bögeholz, L. A. K.; Mercier, E.; Wintermeyer, W.; Rodnina, M. V.: Kinetic control of nascent protein biogenesis by peptide deformylase. Scientific Reports 11, 24457 (2021)

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30.

Journal Article

Petrychenko, V.; Peng, B. Z.; Schwarzer, A. C. d. A. P.; Peske, F.; Rodnina, M. V.; Fischer, N.: Structural mechanism of GTPase-powered ribosome-tRNA movement. Nature Communications 12 (1), 5933 (2021)

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31.

Journal Article

Belardinelli, R.; Sharma, H.; Peske, F.; Rodnina, M. V.: Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation. RNA 27 (9), pp. 981 - 990 (2021)

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32.

Journal Article

Absmeier, E.; Vester, K.; Ghane, T.; Burakovskiy, D. E.; Milon, P.; Imhof, P.; Rodnina, M. V.; Santos, K. F.; Wahl, M. C.: Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. Journal of Biological Chemistry 297 (1), 100829 (2021)

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33.

Journal Article

Mercier, E.; Wang, X.; Maiti, M.; Wintermeyer, W.; Rodnina, M. V.: Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion. Proceedings of the National Academy of Sciences of the USA 118 (26), e2100474118 (2021)

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34.

Journal Article

Wohlgemuth, I.; Garofalo, R.; Samatova, E. N.; Günenç, A. N.; Lenz, C.; Urlaub, H.; Rodnina, M. V.: Translation error clusters induced by aminoglycoside antibiotics. Nature Communications 12, 1830 (2021)

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35.

Journal Article

Ranjan, N.; Pochopien, A. A.; Wu, C. C.-C.; Beckert, B.; Blanchet, S.; Green, R.; Rodnina, M. V.; Wilson, D. N.: Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation. EMBO Journal 40 (6), e106449 (2021)

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36.

Journal Article

Zhang, Y.; Laurentiis, E. D.; Bohnsack, K. E.; Wahlig, M.; Ranjan, N.; Gruseck, S.; Hackert, P.; Wölfle, T.; Rodnina, M. V.; Schwappach, B. et al.; Rospert, S.: Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast. Nature Communications 12, 782 (2021)

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37.

Journal Article

Samatova, E. N.; Daberger, J.; Liutkute, M.; Rodnina, M. V.: Translational control by ribosome pausing in bacteria: How a non-uniform pace of translation affects protein production and folding. Frontiers in Microbiology 11, 619430 (2021)

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38.

Journal Article

Lavdovskaia, E.; Denks, K.; Nadler, F.; Steube, E.; Linden, A.; Urlaub, H.; Rodnina, M. V.; Richter-Dennerlein, R.: Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes. Nucleic Acids Research 48 (22), pp. 12929 - 12942 (2020)

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39.

Journal Article

Liutkute, M.; Maiti, M.; Samatova, E. N.; Enderlein, J.; Rodnina, M. V.: Gradual compaction of nascent peptide during cotranslational folding on the ribosome. eLife 9, e60895 (2020)

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40.

Journal Article

Chan, K.-H.; Petrychenko, V.; Mueller, C.; Maracci, C.; Holtkamp, W.; Wilson, D. N.; Fischer, N.; Rodnina, M. V.: Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nature Communications 11, 4106 (2020)

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supplementary-material

41.

Journal Article

Mercier, E.; Wintermeyer, W.; Rodnina, M. V.: Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 39 (15), e104054 (2020)

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supplementary-material

42.

Journal Article

O'Loughlin, S.; Capece, M. C.; Klimova, M.; Wills, N. M.; Coakley, A.; Samatova, E. N.; O'Connor, P.k. B. F.; Loughran, G.; Weissman, J. S.; Baranov, P. V. et al.; Rodnina, M. V.; Puglisi, J.h. D.; Atkins, J. F.: Polysomes bypass a 50-nucleotide coding gap less efficiently than monosomes due to attenuation of a 5′ mRNA stem–loop and enhanced drop-off. Journal of Molecular Biology 432 (16), pp. 4369 - 4387 (2020)

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43.

Journal Article

Rodnina, M. V.; Korniy, N.; Klimova, M.; Karki, P.; Peng, B. Z.; Senyushkina, T.; Belardinelli, R.; Maracci, C.; Wohlgemuth, I.; Samatova, E. N. et al.; Peske, F.: Translational recoding: Canonical translation mechanisms reinterpreted. Nucleic Acids Research 48 (3), pp. 1056 - 1067 (2020)

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44.

Journal Article

Liutkute, M.; Samatova, E. N.; Rodnina, M. V.: Cotranslational folding of proteins on the ribosome. Biomolecules 10 (1), 97 (2020)

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45.

Journal Article

Peng, B. Z.; Bock, L. V.; Belardinelli, R.; Peske, F.; Grubmüller, H.; Rodnina, M. V.: Active role of elongation factor G in maintaining the mRNA reading frame during translation. Science Advances 5 (12), eaax8030 (2019)

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46.

Journal Article

Rodnina, M. V.; Peske, F.; Peng, B. Z.; Belardinelli, R.; Wintermeyer, W.: Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 401 (1), pp. 131 - 142 (2019)

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47.

Journal Article

Bock, L. V.; Caliskan, N.; Korniy, N.; Peske, F.; Rodnina, M. V.; Grubmüller, H.: Thermodynamic control of −1 programmed ribosomal frameshifting. Nature Communications 10, 4598 (2019)

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48.

Journal Article

Korniy, N.; Samatova, E. N.; Anokhina, M. M.; Peske, F.; Rodnina, M. V.: Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 593 (13), pp. 1468 - 1482 (2019)

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49.

Journal Article

Ranjan, N.; Leidel, S. A.: The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin? FEBS Letters 593 (13), pp. 1483 - 1493 (2019)

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50.

Journal Article

Klimova, M.; Senyushkina, T.; Samatova, E. N.; Peng, B. Z.; Pearson, M.; Peske, F.; Rodnina, M. V.: EF-G-induced ribosome sliding along the noncoding mRNA. Science Advances 5 (6), eaaw9049 (2019)

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