15 November 2019 Our paper on the effect of ER-aminopeptidase 1 on the processing and presentation of immunotherapy-relevant melanoma epitopes is now published in the European Journal of Immunology. more

15 November 2019 Our paper introducing an in silico—in vitro pipeline identifying an HLA-A^*02:01⁺ KRAS G12V⁺ spliced epitope candidate for a broad tumor-immune response in cancer patients was published in Frontiers in Immunology. more

23 October 2019 Juliane Liepe gives a seminar on “Systems Biology of the MHC-I antigen presentation pathway"  at Melbourne Integrative Genomics Center, University of Melbourne (Melbourne, Australia).

01 October 2019 Hanna will continue to work with us on characterisation and prediction of proteasome-catalysed peptide splicing using Deep Learning.

12 September 2019 Yehor presented his work "Characterization of MHC-I immunopeptidome to eradicate senescent lymphoma cells after Doxorubicin chemotherapy” on a poster at the ICSA (Cellular senescence - The bright & dark side) in Athens.

01 August 2019 Hanna Rötschke joined our team. Welcome, Hanna! Hanna is doing a summer internship with us, before starting her BSc studies in Biochemistry at the University of Göttingen. She will work with our team on the systems biology of the MHC-I antigen presentation pathway.

19 June 2019 Our group went on a hiking trip to the Harz mountains. We visited the Unicorn Cave and the ruins of Schwarzfels near Herzberg.

13-15 June 2019 The second IMPRS-GS retreat took place in Volpriehausen. All students of the program presented their work, networked and exchanged ideas. Sarah gave a talk and Artem and Yehor presented their work on posters.

10 May 2019 Our work on the differences between the 20S thymoproteasome and immunoproteasome and the effect on the processing of antigens associated to tumors and autoimmune diseases is published in Journal of Biological Chemistry. more

26 April 2019: Sarah presented her work on "Bayesian statistical inference based on MCMC facilitates the analysis of protease dynamics using tandem mass spectrometry measurements" at the workshop MASAMB 2019 at EMBL-EBI in Cambridge. She won a prize for giving the best student talk. Congratulations Sarah! more

April 2019 We welcome Sophie-Asako Xerri to our team!

01 April 2019 Yehor will do his PhD with us on multi-omics integration for immune epitope prediction.

20 March 2019 Our paper on modelling the dynamics of the extracellular proteasome osteopontin circuit in Multiple Sclerosis is out in Cells. more

05 March 2019 We welcome Gerd Specht to our team! Gerd will join us to work on his Bachelor thesis.

01 February 2019 Debdas Paul joins our team as postdoc. Welcome Debdas! He will work on machine learning approaches in immunology.
 

January 2019 Our paper showing the frequency and characteristics of spliced peptides in cancer cell lines is now published in Cancer Immunology Research. more