Our publicaton “Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing” is now available in Nature Communications. more

02. November 2023 The team of Melina Schuh published their paper “Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices” in Cell. Congratulations to Yehor, Iina, and Juliane who collaborated with the Schuh lab on this paper. more

19. September 2023 Wai Tuck attended a conference at his alma mater, University of Salzburg in Austria. He presented his work on the Identification and Characterization of spliced peptides catalyzed by human 20S proteasomes. Wai Tuck is supported by the Marie Skłodowska-Curie Actions postdoctoral fellowship.

26. July 2023 We held a very successful retreat in Caparica, Portugal. Days consisted of a group work, presentations by team members, and scientific discussion.

20. July 2023 Congratulations to Hanna and Nyet Cheng who won 2 of the 3 awards for most excellent posters presented at the 5th International Caparica Conference in SPLICING 2023, Caparica, Portugal.

18. July 2023 Congratulations to Hanna, John, Julia, Lara, Martin, Nyet Cheng, Sahil, Wai Tuck, and Yehor who all presented posters at the 5th International Caparica Conference in SPLICING 2023, Caparica, Portugal.

17. July 2023 Congratulations to Hanna, Wai Tuck, Yehor, John, and Juliane who all gave short talks at the 5th International Caparica Conference in SPLICING 2023, Caparica, Portugal. It was the first time presenting at a conference for Hanna, Yehor, and John. This work was co-funded by ERC. Wai Tuck is supported by the Marie Skłodowska-Curie Actions postdoctoral fellowship.

16. July 2023 Our team is travelling to the 5th International Caparica Conference in SPLICING 2023, Caparica, Portugal at which multiple group members will give talks and present posters. After the conference, the we will remain in Caparica for a team retreat.

25. June 2023 Wai Tuck got nominated by the European Commission (Marie Skłodowska-Curie Actions) to attend the 72nd Lindau Nobel Laureate Meeting. Together with 600 young scientists and Nobel laureates, they spent a week (25-30th June 2023) in Lindau to foster scientific exchange among them. Wai Tuck is supported by the Marie Skłodowska-Curie Actions postdoctoral fellowship.

03. Mai 2023 Hanna presented her work about “Insights into proteasome catalysis gained from in vitro experiments - the key towards understanding MHC-I epitope generation?” at the Immunology Interest Group Seminar at the Francis Crick Institute.
 

6. February 2023 We warmly welcome Julia Stachowiak to our team! 
Julia is a medical student and joined us for her medical doctoral thesis. She will be working on neoepitopes in oncological diseases.

12. January 2023 Congratulations to John who presented at the MPI-NAT campus seminar. John gave a talk entitled “The Search for Immunogenic Peptides: Finding Needles in Haystacks”.

10. Januar 2023 Our paper “InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides” is now available in Scientific Data. more

The Deutschlandstipendium supports talented and high-performing students. Congratulations!
After her internship at QSB, Lara will continue to work with us on the proteasome as student assistant.

18. November 2022 We hosted a very successful edition of the institute’s Happy Hour! It was a night of music, cocktails, and good conversation as the first snow of winter came down outside.

November 4, 2022  Hanna held a workshop on the newly developed affinitySPI tool. affinitySPI identifies immunologically relevant peptides.

21. October 2022 Hanna graduated from her BSc studies in Biochemistry and moved to the Molecular Immunobiology group of Dr. Michele Mishto at Kings College London to conduct her PhD studies. We are happy that Hanna will remain a team member of QSB through extended research stays (Front to back: Hanna Rötschke, Hassnae Afrache, Connie Fourny, KCL).
 

20. October 2022 Our paper “inSPIRE: An open-source tool for increased mass spectrometry identification rates using Prosit spectral prediction” is now available in Molecular & Cellular Proteomics. more

15. October 2022 To further increase interaction and exchange between 'wet' and 'dry' labs, we have weekly joint group meetings between QSB and the Molecular Immunobiology group of Dr. Michele Mishto at King's College and the Francis Crick Institute in London.

03. October 2022 Our paper “iBench:  A ground truth approach for advanced validation of mass spectrometry identification method” is now available in Proteomics. more

04. July 2022 We warmly congratulate Dr. Sarah Henze, who received her PhD at QSB. Sarah was awarded her PhD for her research into absolute quantification of peptides with a computational approach using Bayesian inference.

20. April 2022 We warmly congratulate Dr. Artem Mansurkhodzhaev who was awarded his PhD. Artem earned his PhD for his research into the role of proteasome generated spliced peptides in the adaptive immune response, immune evasion by pathogens and autoimmunity.