We Published!

We Published!

10. Januar 2023 Our paper “InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides” is now available in Scientific Data. more

News of 2022

Lara receives Deutschlandstipendium (German Scholarship)

Lara receives Deutschlandstipendium (German Scholarship)

The Deutschlandstipendium supports talented and high-performing students. Congratulations!
After her internship at QSB, Lara will continue to work with us on the proteasome as student assistant.
QSB hosts Happy Hour!

QSB hosts Happy Hour!

18. November 2022 We hosted a very successful edition of the institute’s Happy Hour! It was a night of music, cocktails, and good conversation as the first snow of winter came down outside.
Hanna holds online workshop on the new affinitySPI  software tool.

Hanna holds online workshop on the new affinitySPI  software tool.

November 4, 2022  Hanna held a workshop on the newly developed affinitySPI tool. affinitySPI identifies immunologically relevant peptides.
Hanna moved to London!

Hanna moved to London!

21. October 2022 Hanna graduated from her BSc studies in Biochemistry and moved to the Molecular Immunobiology group of Dr. Michele Mishto at Kings College London to conduct her PhD studies. We are happy that Hanna will remain a team member of QSB through extended research stays (Front to back: Hanna Rötschke, Hassnae Afrache, Connie Fourny, KCL).
 
Wai Tuck and Nyet Cheng arrive in London!

Wai Tuck and Nyet Cheng arrive in London!

21. October 2022 To learn new techniques and collect data for their projects Wai Tuck and Nyet Cheng are currently on a research stay for 10 weeks hosted by the Molecular Immunobiology group of Dr. Michele Mishto at the Francis Crick institute in London (left to right: Ying Thong (Crick), Nyet Cheng Chiam (QSB), Wai Tuck Soh (QSB) and Bei Fang Teo (Crick)).
We published!

We published!

20. October 2022 Our paper “inSPIRE: An open-source tool for increased mass spectrometry identification rates using Prosit spectral prediction” is now available in Molecular & Cellular Proteomics. more
From Göttingen to London and back.

From Göttingen to London and back.

15. October 2022 To further increase interaction and exchange between 'wet' and 'dry' labs, we have weekly joint group meetings between QSB and the Molecular Immunobiology group of Dr. Michele Mishto at King's College and the Francis Crick Institute in London.
We published!

We published!

03. October 2022 Our paper “iBench:  A ground truth approach for advanced validation of mass spectrometry identification method” is now available in Proteomics. more
Welcome Martin!

Welcome Martin!

October 01. 2022 A warm welcome to Martin Pašen! Martin started as a PhD student in our team. His project will focus on on quantitative and statistical approaches to modelling the APP (antigen processing and presentation) pathway.
John presents poster at theHorizons in Molecular Biology Symposium

John presents poster at the
Horizons in Molecular Biology Symposium

15. September 2022 John presented a poster on “iBench & inSPIRE: Getting peptide sequences right” at the 19th Horizons in Molecular Biology Symposium.
Wai Tuck attends Advanced Proteomics Summer School!

Wai Tuck attends Advanced Proteomics Summer School!

31. July 2022 Wai Tuck took part the 14th Advanced Proteomics Summer School. At the conference, he presented a poster on Characterization of the Antigen Processing by Proteasomes.
Sarah Graduates!

Sarah Graduates!

04. July 2022 We warmly congratulate Dr. Sarah Henze, who received her PhD at QSB. Sarah was awarded her PhD for her research into absolute quantification of peptides with a computational approach using Bayesian inference.
Welcome Iina!

Welcome Iina!

01. June 2022 We warmly welcome Iina Takala to our team! Iina has joined our team after completing her masters at the University of Turku. She is working on multi-omics analysis of proteasome subtype expression effects.
Welcome Sahil!

Welcome Sahil!

01. June 2022 A warm welcome to Sahil Khan! Sahil has started as a PhD student on our team. His project will focus on developing a mechanistic model for APP (Antigen Processing and Presentation) pathway.
Welcome, Lara!

Welcome, Lara!

02 May 2022 Lara has joined our team, welcome! Lara is doing a 3-months internship before starting her BSc studies in Biochemistry in October. During her time here she will get introduced to enzyme biochemistry, experimental work e.g. pipetting and computer-based data analysis.
Artem Graduates!

Artem Graduates!

20. April 2022 We warmly congratulate Dr. Artem Mansurkhodzhaev who was awarded his PhD. Artem earned his PhD for his research into the role of proteasome generated spliced peptides in the adaptive immune response, immune evasion by pathogens and autoimmunity.
Wai Tuck is awarded the Marie Sklodowska-Curie Actions fellowship!

Wai Tuck is awarded the Marie Sklodowska-Curie Actions fellowship!

21 Mar 2022 We congratulate Wai Tuck for being awarded the Marie Sklodowska-Curie Actions fellowship by the European Commission! The project is about PROTAC-driven Protein degradation by Proteasome during Antigen Processing and Presentation (ProAPP) and will be funded for 24 months. more

Welcome, Vera!

14 Mar 2022 We welcome Vera Subrakova to our team! Vera studies Biotechnology at AgroParisTech University Paris and joins us for a 6-month master project. She is interested in anti-cancer drug development and with us she will work on the prediction of peptide splicing in order to identify possible cancer-specific spliced peptides.
Welcome, Nyet Cheng!

Welcome, Nyet Cheng!

01 March 2022 A warm welcome to Nyet Cheng Chiam, who joins our team as postdoc! Nyet Cheng is a trained molecular biologist and she will work experimentally on proteasome-mediated antigen processing and MHC-1 presentation.
John holds internal online workshop on the rescoring tool Caravan

John holds internal online workshop on the rescoring tool Caravan

25 Feb 2022 Caravan uses Percolator and Prosit tools to generate high confidence peptide-spectrum matches from mass spectrometry search results using recent advances in spectral prediction.

Welcome, Lorenz!

21 Feb 2022 We welcome Lorenz Mammen to our team! Lorenz is currently doing his undergraduate studies in biology and maths at the University of Tuebingen. He joins us for an internship of six weeks. During his stay, he will work on modelling of the antigen presenting pathway.
We published!

We published!

20 Feb 2022 Our paper “Database search engines and target database features impinge upon the identification of post-translationally cis-spliced peptides in HLA class I immunopeptidomes” was published in Proteomics. more
Hanna receives PhD studentship from Wellcome Trust UK!

Hanna receives PhD studentship from Wellcome Trust UK!

31 Jan 2022 Hanna receives a PhD studentship from the Wellcome Trust in UK. Congratuations, Hanna! She will join the Neuro-Immune Interactions in Health & Disease Programme at King's College London in September. more
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