Publications of Thomas Güttler

Solà Colom, M.; Fu, Z.; Gunkel, P.; Güttler, T.; Trakhanov, S.; Srinivasan, V.; Gregor, K.; Pleiner, T.; Görlich, D.: A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies. The EMBO Journal 43 (11), pp. 2198 - 2232 (2024)

Aksu, M.; Kumar, P.; Güttler, T.; Taxer, W.; Gregor, K.; Mußil, B.; Rymarenko, O.; Stegmann, K.M.; Dickmanns, A.; Gerber, S. et al.; Reineking, W.; Schulz, C.; Henneck, T.; Mohamed, A.; Pohlmann, G.; Ramazanoglu, M.; Mese, K.; Groß, U.; Ben-Yedidia, T.; Ovadia, O.; Fischer, D.W.; Kamensky, M.; Reichman, A.; Baumgärtner, W.; von Köckritz-Blickwede, M.; Dobbelstein, M.; Görlich, D.: Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters. Antiviral Research 221, 105778 (2024)

Güttler, T.; Dobbelstein, M.; Görlich, D.: Therapeutische Nanobodies gegen SARS-CoV-2. Biospektrum 28, pp. 39 - 42 (2022)

Güttler, T.; Aksu, M.; Dickmanns, A.; Stegmann, K. M.; Gregor, K.; Rees, R.; Taxer, W.; Rymarenko, O.; Schünemann, J.; Dienemann, C. et al.; Gunkel, P.; Mussil, B.; Krull, J.; Teichmann, U.; Groß, U.; Cordes, V.; Dobbelstein, M.; Görlich, D.: Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 40 (19), e107985 (2021)

Ng, S. C.; Güttler, T.; Görlich, D.: Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide. Nature Communications 12, 4047 (2021)

Güttler, T.; Görlich, D.: Ran-dependent nuclear export mediators: A structural perspective. EMBO Journal 30 (17), pp. 3457 - 3474 (2011)

Madl, T.; Güttler, T.; Görlich, D.; Sattler, M.: Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements. Angewandte Chemie International Edition 50 (17), pp. 3993 - 3997 (2011)

Güttler, T.; Madl, T.; Neumann, P.; Deichsel, D.; Lorenzo, C.; Monecke, T.; Ficner, R.; Sattler, M.; Görlich, D.: NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nature Structural and Molecular Biology 17 (11), pp. 1367 - 1376 (2010)

Mohr, D.; Frey, S.; Fischer, T.; Güttler, T.; Görlich, D.: Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO Journal 28, pp. 2541 - 2553 (2009)

Monecke, T.; Güttler, T.; Neumann, P.; Dickmanns, A.; Görlich, D.; Ficner, R.: Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Science 324 (5930), pp. 1087 - 1091 (2009)

Gontan, C.; Güttler, T.; Engelen, E.; Demmers, J.; Fornerod, M.; Grosveld, F.; Tibboel, D.; Görlich, D.; Poot, A.; Rottier, R.: Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. Journal of Cell Biology 185 (1), pp. 27 - 34 (2009)

Hantschel, O.; Wiesner, S.; Güttler, T.; Mackereth, C. D.; Remsing Rix, L. L.; Mikes, Z.; Dehne, J.; Görlich, D.; Sattler, M.; Superti-Furga, G.: Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl. Molecular Cell 19 (4), pp. 461 - 473 (2005)

Gontan, P.; Güttler, T.; Demmers, J.; Grosveld, F.; Tibboel, D.; Fornerod, M.; Görlich, D.; Poot, R.; Rottier, R.: Interactors of Sox2 in embryonic stem cells. Developmental Biology 319 (2), pp. 553 - 554 (2008)

Güttler, T.: Structural and functional analysis of exportin-cargo recognition. Dissertation, Universität Göttingen, Göttingen (2010)