Publikationen von Tiago Fleming Outeiro

Ali, T. T.; Merghani, M.; Al-Azzani, M.; Gatzemeier, L. M.; Hoppert, M.; Kaloyanova, D.; Outeiro, T. F.; Neumann, P.; Popova, B.; Braus, G. H.: Rationally designed peptides inhibit the formation of α-synuclein fibrils and oligomers. European Journal of Medicinal Chemistry 289, 117452 (2025)

Amaral, L.; Martins, M.; Côrte-Real, M.; Outeiro, T. F.; Chaves, S. R.; Rego, A.: The neurotoxicity of pesticides: Implications for Parkinson's disease. Chemosphere 377, 144348 (2025)

Koss, D. J.; Todd, O.; Menon, H.; Anderson, Z.; Yang, T.; Findlay, L.; Graham, B.; Palmowski, P.; Porter, A.; Morrice, N. et al.; Walker, L.; Attems, J.; Ghanem, S. S.; El-Agnaf, O.; LeBeau, F. E.; Erskine, D.; Outeiro, T. F.: A reciprocal relationship between markers of genomic DNA damage and alpha-synuclein pathology in dementia with Lewy bodies. Molecular Neurodegeneration 20, 34 (2025)

Laurent, C.; Poncet, G.; Herskovits, T.; Alves de Sousa, R.; Le Corre, L.; Al-Azzani, M.; Koenig, A.; Birman, S.; Outeiro, T. F.; Mansuy, D. et al.; Dairou, J.: Inhibition of the Parkinson’s Disease-Related Protein DJ-1 by Endogenous Neurotoxins of the 1,2,3,4-Tetrahydroisoquinoline Family. ACS Chemical Neuroscience 16 (6), S. 1034 - 1042 (2025)

Flores-León, M.; Outeiro, T. F.: Expanding our understanding of synucleinopathies: proteinopathy, proteinopenia, and lipidopathy. The FEBS Journal (2025)

Coles, N. P.; Elsheikh, S.; Quesnel, A.; Butler, L.; Jennings, C.; Tarzi, C.; Achadu, O. J.; Islam, M.; Kalesh, K.; Occhipinti, A. et al.; Angione, C.; Marles-Wright, J.; Koss, D. J.; Thomas, A. J.; Outeiro, T. F.; Filippou, P. S.; Khundakar, A. A.: Molecular Insights into α-Synuclein Fibrillation: A Raman Spectroscopy and Machine Learning Approach. ACS Chemical Neuroscience 16 (4), S. 687 - 698 (2025)

Outeiro, T. F.; Höglinger, G.; Lang, A. E.; Vieira, T. C. R. G.: Protein misfolding: understanding biology to classify and treat synucleinopathies. Journal of Neural Transmission (2025)

Lang, A. E.; Höglinger, G. U.; Adler, C. H.; Berg, D.; Klein, C.; Outeiro, T. F.; Poewe, W.; Postuma, R.; Stoessl, A. J.: Initial biological classification of Lewy body diseases: No consensus on terminology. Alzheimer's & Dementia 21 (2), e14449 (2025)

da Silva, I. S.; Cardoso, A. R.; Reimer, L.; König, A.; van Riesen, C.; Outeiro, T. F.; Jensen, P. H.; Sales, M. G. F.: α-Synuclein plastic antibody applied to monitor monomeric structures and discriminate aggregated forms in human CSF. Biosensors and Bioelectronics 268, 116880 (2025)

Fonseca-Fonseca, L. A.; Fuentes, N. P.; Sánchez, J. R.; Iglesias, Á. T.; Outeiro, T. F.; Silva, V. D. A. d.; Costa, S. L.; Núñez-Figueredo, Y.: Correlational assessment of the effects of JM-20 in a rat model of parkinsonism. Behavioural Brain Research 476, 115269 (2025)

Coles, N. P.; Elsheikh, S.; Quesnel, A.; Butler, L.; Achadu, O.; Islam, M.; Kalesh, K.; Occhipinti, A.; Angione, C.; Marles-Wright, J. et al.; Koss, D. J.; Thomas, A. J.; Outeiro, T. F.; Filippou, P. S.; Khundakar, A. A.: Alpha-synuclein aggregation induces prominent cellular lipid changes as revealed by Raman spectroscopy and machine learning analysis. Brain Communications 7 (2), fcaf133 (2025)

Soares, E. S.; Queiroz, L. Y.; Gerhardt, E.; Prediger, R. D. S.; Outeiro, T. F.; Cimarosti, H. I.: SUMOylation modulates mitochondrial dynamics in an in vitro rotenone model of Parkinson's disease. Molecular and Cellular Neuroscience 131, 103969 (2024)

Amaro-Leal, Â.; Afonso, A. I.; Machado, F.; Shvachiy, L.; Rocha, I.; Outeiro, T. F.; Geraldes, V.: Dose-Dependent Cognitive Decline, Anxiety, and Locomotor Impairments Induced by Doxorubicin: Evidence from an Animal Model. Biology 13 (11), 939 (2024)

de Bruyn, E.; Dorn, A.E.; Rossetti, G.; Fernandez, C.; Outeiro, T. F.; Schulz, J.B.; Carloni, P.: Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution. Journal of Chemical Information and Modeling 64 (21), S. 8215 - 8226 (2024)

Abdelrasol, H.; Chopra, A.; Shvachiy, L.; Beutner, D.; Outeiro, T. F.; Setz, C.: Stress granules formation in HEI-OC1 auditory cells and in H4 human neuroglioma cells secondary to cisplatin exposure. Cell Stress 8 (1), S. 83 - 98 (2024)

Gatzemeier, L. M.; Meyer, F.; Outeiro, T. F.: Synthesis and Semi-Synthesis of Alpha-Synuclein: Insight into the Chemical Complexity of Synucleinopathies. Chembiochem 25 (20), e202400253 (2024)

Shaib, A. H.; Chouaib, A. A.; Chowdhury, R.; Altendorf, J.; Mihaylov, D.; Zhang, C.; Krah, D.; Imani, V.; Spencer, R. K. W.; Georgiev, S. V. et al.; Mougios, N.; Monga, M.; Reshetniak, S.; Mimoso, T.; Chen, H.; Fatehbasharzad, P.; Crzan, D.; Saal, K.-A.; Alawieh, M. M.; Alawar, N.; Eilts, J.; Kang, J.; Soleimani, A.; Müller, M.; Pape, C.; Alvarez, L.; Trenkwalder, C.; Mollenhauer, B.; Outeiro, T. F.; Köster, S.; Preobraschenski, J.; Becherer, U.; Moser, T.; Boyden, E. S.; Aricescu, A. R.; Sauer, M.; Opazo, F.; Rizzoli, S. O.: One-step nanoscale expansion microscopy reveals individual protein shapes. Nature Biotechnology (2024)

Fonseca-Gomes, J.; Costa-Coelho, T.; Ferreira-Manso, M.; Inteiro-Oliveira, S.; Vaz, S.H.; Alemãn-Serrano, N.; Atalaia-Barbacena, H.; Ribeiro-Rodrigues, L.; Ramalho, R.M.; Pinto, R. et al.; Vicente Miranda, H.; Tanqueiro, S.R.; de Almeida-Borlido, C.; Ramalho, M.J.; Miranda-Lourenço, C.; Belo, R.F.; Ferreira, C.B.; Neves, V.; Rombo, D.M.; Viais, R.; Martins, I.C.; Jerónimo-Santos, A.; Caetano, A.; Manso, N.; Mäkinen, P.; Marttinen, M.; Takalo, M.; Bremang, M.; Pike, I.; Haapasalo, A.; Loureiro, J.A.; Pereira, M.C.; Santos, N.C.; Outeiro, T. F.; Castanho, M.A.R.B.; Fernandes, A.; Hiltunen, M.; Duarte, C.B.; Castrén, E.; de Mendonça, A.; Sebastião, A.M.; Rodrigues, T.M.; Diógenes, M.J.: A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease. Molecular Therapy 32 (10), S. 3372 - 3401 (2024)

da Silva Correia, A.; Schmitz, M.; Fischer, A.; da Silva Correia, S.; Simonetti, F. L.; Saher, G.; Goya‐Maldonado, R.; Arora, A. S.; Fischer, A.; Outeiro, T. F. et al.; Zerr, I.: Cellular prion protein acts as mediator of amyloid beta uptake by caveolin‐1 causing cellular dysfunctions in vitro and in vivo. Alzheimer's & Dementia 20 (10), S. 6776 - 6792 (2024)

Amaral, L.; Mendes, F.; Côrte-Real, M.; Rego, A.; Outeiro, T. F.; Chaves, S. R.: A versatile yeast model identifies the pesticides cymoxanil and metalaxyl as risk factors for synucleinopathies. Chemosphere 364, 143039 (2024)