Publikationen von Luis A. Pardo

Severin, M.; Hansen, R. K.; Rolver, M. G.; Hels, T.; Maeda, K.; Pardo, L. A.; Pedersen, S. F.: Tumor acidosis supports cancer cell lipid uptake via a rapid, transporter-independent mechanism. Journal of Cell Science (2025)

Lohrberg, M.; Mortensen, L. S.; Thomas, C.; Fries, F.; van der Meer, F.; Götz, A.; Landt, C.; Rhee, H. J.; Rhee, J. S.; Gómez-Varela, D. et al.; Schmidt, M.; Möbius, W.; Ruhwedel, T.; Pardo, L. A.; Remling, L.; Kramann, N.; Wrzos, C.; Bahn, E.; Stadelmann, C.; Barrantes-Freer, A.: Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination. Journal of Neuroinflammation 22, 47 (2025)

Sterle, M.; Habjan, E.; Piga, M.; Peršolja, P.; Durcik, M.; Dernovšek, J.; Szili, P.; Czikkely, M. S.; Zidar, N.; Janez, I. et al.; Pal, C.; Accetto, T.; Pardo, L. A.; Kikelj, D.; Peterlin Mašič, L.; Tomašič, T.; Bitter, W.; Cotman, A. E.; Speer, A.; Zega, A.: Development of narrow-spectrum topoisomerase-targeting antibacterials against mycobacteria. European Journal of Medicinal Chemistry 276, 116693 (2024)

Abdelaziz, R.; Tomczak, A. P.; Neef, A.; Pardo, L. A.: Revealing a hidden conducting state by manipulating the intracellular domains in K_V10.1 exposes the coupling between two gating mechanisms. eLife 12, RP91420 (2024)

Gubič, Š.; Montalbano, A.; Sala, C.; Becchetti, A.; Hendrickx, L. A.; Theemsche, K. M. V.; Pinheiro-Junior, E. L.; Altadonna, G. C.; Peigneur, S.; Ilaš, J. et al.; Labro, A. J.; Pardo, L. A.; Tytgat, J.; Tomašič, T.; Arcangeli, A.; Mašič, L. P.: Immunosuppressive effects of new thiophene-based K_V1.3 inhibitors. European Journal of Medicinal Chemistry 259, 115561 (2023)

Pardo, L. A.: Ion Channel Lateral Diffusion Reveals the Maturation Process of the Neuronal Actin Cytoskeleton. Function 4 (4), zqad029 (2023)

Severin, M.; Pedersen, E.L.; Borre, M.T.; Axholm, I.; Christiansen, F.B.; Ponniah, M.; Czaplinska, D.; Larsen, T.; Pardo, L. A.; Pedersen, S.F.: Dynamic localization of the Na⁺-HCO₃^- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia. Journal of Cell Science 136 (7), jcs260687 (2023)

Durcik, M.; Cotman, A. E.; Toplak, Ž.; Možina, Š.; Skok, Ž.; Szili, P. E.; Czikkely, M.; Maharramov, E.; Vu, T. H.; Piras, M. V. et al.; Zidar, N.; Ilaš, J.; Zega, A.; Trontelj, J.; Pardo, L. A.; Hughes, D.; Huseby, D.; Berruga-Fernández, T.; Cao, S.; Simoff, I.; Svensson, R.; Korol, S. V.; Jin, Z.; Vicente, F.; Ramos, M. C.; Mundy, J. E. A.; Maxwell, A.; Stevenson, C. E. M.; Lawson, D. M.; Glinghammar, B.; Sjöström, E.; Bohlin, M.; Oreskär, J.; Alvér, S.; Janssen, G. V.; Sterk, G. J.; Kikelj, D.; Pal, C.; Tomašič, T.; Mašič, L. P.: New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus. Journal of Medicinal Chemistry 66 (6), S. 3968 - 3994 (2023)

Pardo, L. A.: Watching Ion Channels on the Move. Function 4 (1), zqac072 (2022)

Rolver, M. G.; Holland, L. K. K.; Ponniah, M.; Prasad, N. S.; Yao, J.; Schnipper, J.; Kramer, S.; Elingaard-Larsen, L.; Pedraz-Cuesta, E.; Liu, B. et al.; Pardo, L. A.; Maeda, K.; Sandelin, A.; Pedersen, S. F.: Chronic acidosis rewires cancer cell metabolism through PPARα signaling. International Journal of Cancer 152 (8), S. 1668 - 1684 (2022)

Gubič, Š.; Toplak, Ž.; Shi, X.; Dernovšek, J.; Hendrickx, L. A.; Pinheiro-Junior, E. L.; Peigneur, S.; Tytgat, J.; Pardo, L. A.; Mašič, L. P. et al.; Tomašič, T.: New Diarylamine K_V10.1 Inhibitors and Their Anticancer Potential. Pharmaceutics 14 (9), 1963 (2022)

Wildung, M.; Herr, C.; Riedel, D.; Wiedwald, C.; Moiseenko, A.; Ramirez, F.; Tasena, H.; Heimerl, M.; Alevra, M.; Movsisyan, N. et al.; Schuldt, M.; Volceanov-Hahn, L.; Provoost, S.; Noethe-Menchen, T.; Urrego, D.; Freytag, B.; Wallmeier, J.; Beisswenger, C.; Bals, R.; van den Berge, M.; Timens, W.; Hiemstra, P. S.; Brandsma, C.-A.; Maes, T.; Andreas, S.; Heijink, I. H.; Pardo, L. A.; Lize, M.: miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly. International Journal of Molecular Sciences 23 (14), 7749 (2022)

Pardo, L. A.: Voltage-Gated Potassium Channels Beyond the Action Potential. Bioelectricity 4 (2), S. 117 - 125 (2022)

Gubic, S.; Hendrickx, L. A.; Shi, X.; Toplak, Z.; Mozina, S.; Van Theemsche, K. M.; Pinheiro-Junior, E. L.; Peigneur, S.; Labro, A. J.; Pardo, L. A. et al.; Tytgat, J.; Tomasic, T.; Masic, L. P.: Design of New Potent and Selective Thiophene-Based K_V1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 14 (11), 2595 (2022)

Toplak, Z.; Hendrickx, L. A.; Abdelaziz, R.; Shi, X.; Peigneur, S.; Tomasic, T.; Tytgat, J.; Peterlin-Masic, L.; Pardo, L. A.: Overcoming challenges of HERG potassium channel liability through rational design: Eag1 inhibitors for cancer treatment. Medicinal Research Reviews (2022)

Vieira, A. M.; Zahed, F.; Crispim, A. C.; de Souza Bento, E.; de Freitas Oliveira França, R.; Pinheiro, I. O.; Pardo, L. A.; Carvalho, B. M.: Production of levan from Bacillus subtilis var. natto and apoptotic effect on SH-SY5Y neuroblastoma cells. Carbohydrate Polymers 273, 118613 (2021)

Gubic, S.; Hendrickx, L. A.; Toplak, Z.; Sterle, M.; Peigneur, S.; Tomasic, T.; Pardo, L. A.; Tytgat, J.; Zega, A.; Masic, L. P.: Discovery of K_V1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges. Medicinal Research Reviews 41 (4), S. 2423 - 2473 (2021)

Pedersen, S. F.; Flinck, M.; Pardo, L. A.: The interplay between dysregulated ion transport and mitochondrial architecture as a dangerous liaison in cancer. International Journal of Molecular Sciences 22 (10), 5209 (2021)

Ghazaryan, N.; Movsisyan, N.; Macedo, J. C.; Vaz, S.; Ayvazyan, N.; Pardo, L. A.; Logarinho, E.: Macrovipera lebetina obtusa Snake Venom as a Modulator of Antitumor Effect in S-180 Sarcoma Mouse Model. Molecular Biology 55 (3), S. 405 - 412 (2021)

Ghazaryan, N.; Movsisyan, N.; Macedo, J. C.; Vaz, S.; Ayvazyan, N.; Pardo, L.; Logarinho, E.: The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model. Investigational new drugs, 10.1007/s1037-019-00734-2 (2019)