Publikationen von Julia M. Edgar

Steyer, A. M.; Buscham, T. J.; Lorenz, C.; Hümmert, S.; Eichel‐Vogel, M. A.; Schadt, L. C.; Edgar, J. M.; Köster, S.; Möbius, W.; Nave, K.-A. et al.; Werner, H. B.: Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag. Glia 71 (3), S. 509 - 523 (2023)

Edgar, J. M.; McGowan, E.; Chapple, K. J.; Möbius, W.; Lemgruber, L.; Insall, R. H.; Nave, K.-A.; Boullerne, A.: Río‐Hortega's drawings revisited with fluorescent protein defines a cytoplasm‐filled channel system of CNS myelin. Journal of Anatomy 239 (6), S. 1241 - 1255 (2021)

Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L.; Depp, C.; Sasmita, A. O.; Vasileva, M. H.; Scholz, P.; Zhao, Y.; Krüger, D. et al.; Wichert, S.; Brown, E. R.; Michail, K.; Nave, K.-A.; Bonn, S.; Odoardi, F.; Rossner, M.; Ischebeck, T.; Edgar, J. M.; Saher, G.: Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice. Cell Reports 37 (4), 109889 (2021)

Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L.; Schlaphoff, L.; Depp, C.; Düking, T.; Winchenbach, J.; Neuber, J.; Ewers, D. et al.; Scholz, P.; van der Meer, F.; Cantuti-Castelvetri, L.; Sasmita, A. O.; Meschkat, M.; Ruhwedel, T.; Möbius, W.; Sankowski, R.; Prinz, M.; Huitinga, I.; Sereda, M. W.; Odoardi, F.; Ischebeck, T.; Simons, M.; Stadelmann-Nessler, C.; Edgar, J. M.; Nave, K.-A.; Saher, G.: Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis. Nature Neuroscience 24, S. 47 - 60 (2021)

Gruenenfelder, F. I.; McLaughlin, M.; Griffiths, I. R.; Garbern, J.; Thomson, G.; Kuzman, P.; Barrie, J. A.; McCulloch, M.-l.; Penderis, J.; Stassart, R. et al.; Nave, K.-A.; Edgar, J. M.: Neural stem cells restore myelin in a demyelinating model of Pelizaeus-Merzbacher disease. Brain 143 (5), S. 1383 - 1399 (2020)

Stassart, R. M.; Möbius, W.; Nave, K.-A.; Edgar, J. M.: The Axon-myelin unit in development and degenerative disease. Frontiers in Neuroscience 12, 467 (2018)

Cumberworth, S. L.; Barrie, J. A.; Cunningham, M. E.; Gomes de Figueiredo, D. P.; Schultz, V.; Wilder-Smith, A. J.; Brennan, B.; Pena, L. J.; Freitas de Oliveira França, R.; Linington, C. et al.; Barnett, S. C.; Willison, H. J.; Kohl, A.; Edgar, J. M.: Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected. Acta neuropathologica communications 5, 50 (2017)

Berghoff, S. A.; Gerndt, N.; Winchenbach, J.; Stumpf, S. K.; Hosang, L.; Odoardi, F.; Ruhwedel, T.; Böhler, C.; Barrette, B.; Stassart, R. et al.; Liebetanz, D.; Dibaj, P.; Möbius, W.; Edgar, J. M.; Saher, G.: Dietary cholesterol promotes repair of demyelinated lesions in the adult brain. Nature Communications 8, 14241 (2017)

Goebbels, S.; Wieser, G. L.; Pieper, A.; Spitzer, S.; Weege, B.; Yan, K.; Edgar, J. M.; Yagensky, O.; Wichert, S. P.; Agarwal, A. et al.; Karram, K.; Renier, N.; Tessier-Lavigne, M.; Rossner, M. J.; Káradóttir, R. T.; Nave, K.-A.: A neuronal PI(3,4,5)P₃-dependent program of oligodendrocyte precursor recruitment and myelination. Nature Neuroscience 20 (1), S. 10 - 15 (2017)

Prukop, T.; Epplen, D. B.; Nientiedt, T.; Wichert, S. P.; Fledrich, R.; Stassart, R. M.; Rossner, M. J.; Edgar, J. M.; Werner, H. B.; Nave, K.-A. et al.; Sereda, M. W.: Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model. The American Journal of Human Genetics 94 (4), S. 533 - 546 (2014)

Richert, S.; Kleinecke, S.; Günther, J.; Schaumburg, F.; Edgar, J.; Nienhaus, G. U.; Nave, K.-A.; Kassmann, C. M.: In vivo labeling of peroxisomes by photoconvertible mEos2 in myelinating glia of mice. Biochimie 98, S. 127 - 134 (2014)

Snaidero, N.; Möbius, W.; Czopka, T.; Hekking, L. H. P.; Mathisen, C.; Verkleij, D.; Goebbels, S.; Edgar, J.; Merkler, D.; Lyons, D. A. et al.; Nave, K.-A.; Simons, M.: Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue. Cell 156 (1-2), S. 277 - 290 (2014)

Barrette, B.; Nave, K.-A.; Edgar, J. M.: Molecular triggers of neuroinflammation in mouse models of demyelinating diseases. Biological Chemistry 394 (12), S. 1571 - 1581 (2013)

Monasterio-Schrader, P. d.; Patzig, J.; Möbius, W.; Barrette, B.; Wagner, T. L.; Kusch, K.; Edgar, J. M.; Brophy, P. J.; Werner, H. B.: Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2. Glia 61 (11), S. 1832 - 1847 (2013)

Ip, C. W.; Kroner, A.; Groh, J.; Huber, M.; Klein, D.; Spahn, I.; Diem, R.; Williams, S. K.; Nave, K.-A.; Edgar, J. M. et al.; Martini, R.: Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. PLoS One 7 (8), e42554 (2012)

Fünfschilling, U.; Supplie, L. M.; Mahad, D.; Boretius, S.; Saab, A. S.; Edgar, J. M.; Brinkmann, B. G.; Kassmann, C. M.; Tzvetanova, I.; Möbius, W. et al.; Diaz, F.; Meijer, D.; Suter, U.; Hamprecht, B.; Sereda, M. W.; Moraes, C. T.; Frahm, J.; Goebbels, S.; Nave, K.-A.: Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature 485 (7399), S. 517 - 521 (2012)

Karim, S. A.; Barrie, J. A.; McCulloch, M. C.; Montague, P.; Edgar, J. M.; Iden, D. L.; Anderson, T. J.; Nave, K.-A.; Griffiths, I. R.; McLaughlin, M.: PLP/DM20 expression and turnover in a transgenic mouse model of Pelizaeus-Merzbacher disease. Glia 58 (14), S. 1727 - 1738 (2010)

Edgar, J. M.; McCulloch, M. C.; Montague, P.; Brown, A. M.; Thilemann, S.; Pratola, L.; Gruenenfelder, F. I.; Griffiths, I. R.; Nave, K.-A.: Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease. Embo Molecular Medicine 2, S. 42 - 50 (2010)

Edgar, J. M.; Nave, K.-A.: The role of CNS glia in preserving axon function. Current Opinion in Neurobiology 19 (5), S. 498 - 504 (2009)

Karim, S. A.; Barrie, J. A.; McCulloch, M. C.; Montague, P.; Edgar, J. M.; Kirkham, D.; Anderson, T. J.; Nave, K.-A.; Griffiths, I. R.; Mclaughlin, M.: PLP overexpression perturbs myelin protein composition and myelination in a mouse model of Pelizaeus-Merzbacher disease. Glia 55 (4), S. 341 - 351 (2007)